- Must visit
Pinacoteca di Brera
Milan’s premier fine-art gallery, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$73
Average price
$97
Fastest journey
17 h 30 m
Average duration
18 h 19 m
Buses per day
13
Distance
964 km
The best way to find a cheap bus ticket from Messina to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Messina to Milan will cost around $97 if you buy it on the day, but the cheapest tickets can be found for only $73.
Of the 13 buses that leave Messina for Milan on Fri, Jul 10, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 10 the direct buses cover the 964 km distance in an average of 18 h 19 m but if you time it right, some buses will get you there in just 17 h 30 m .
On Fri, Jul 10 the slowest buses will take 19 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2126
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBusOmio recommends booking the bus as it is the most popular option from Messina to Milan among Omio's users. If you are prioritising price take the flight with prices starting from $33. For those with little time consider booking a flight which can get you there in 1h 56m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.9kg. The ticket price range depends on the travel mode: a flight costs an average of $33, and a train costs an average of $69.
Distance: 599 miles (964 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$68 Average price | $134 Average price | $39 Average price Cheapest | $325 Average price (fuel + tolls) |
16h 56m Average total duration 16h 26m Onboard + 30m Additional time* | 16h 13m Average total duration 15h 43m Onboard + 30m Additional time* | 4h 56m Average total duration Fastest 1h 56m Onboard + 3h 0m Additional time* | 12h 43m Average total duration (door-to-door) |
1.0 - 2.4kg CO2 emissions | 0.3 - 0.9kg CO2 emissions Lowest | 2.9 - 5.8kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Messina to Milan:
A flight is $29 (€24) less than a bus for this route with tickets for a bus from Messina to Milan costing on average $68 (€56).
A flight is $96 (€79) less than a train for this route with tickets for a train from Messina to Milan costing on average $134 (€111).
Other travel options to Milan take longer:
Train takes on average 15h 43m.
Bus takes on average 16h 26m.
Tickets start at around $68 (€56) compared to roughly $325 (€267) in fuel and tolls — a saving of about $257 (€212). The journey takes 16h 26m versus 12h 43m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Itabus, FlixBus, BlaBlaCar, Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 09:40PM | Duration 20h10 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 05:55AM | Duration 19h00 | Departure days Everyday | Cheapest price $98 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 07:50AM | Duration 18h25 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 01:45PM | Duration 17h30 | Departure days Everyday | Cheapest price $88 |
Operator Salemi | Departure Time 09:15PM | Arrival Time 01:10PM | Duration 15h55 | Departure days Mon, Wed, Sat | Cheapest price $107 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 05:10PM | Duration 19h40 | Departure days Everyday | Cheapest price $89 |
Operator Itabus | Departure Time 09:35PM | Arrival Time 04:40PM | Duration 19h05 | Departure days Everyday | Cheapest price $73 |
The table below shows live departures for Messina to Milan buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 10:55 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 19h00 | 5:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 10:55 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 25h00 | 11:55 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus | 10:55 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 18h20 | 5:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 8:15 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 17h30 | 1:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 8:15 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 18h20 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 9:30 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 19h40 | 5:10 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:30 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 23h25 | 8:55 PM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus | 9:30 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 21h00 | 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
2126 | 9:35 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 19h05 | 4:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
| Friday, July 10 | |||||
FlixBus · FlixBus | 1:30 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 21h25 | 10:55 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 1:30 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 19h25 | 8:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Messina to Milan run on average 12 times per day, taking around 16h 26m. Cheap bus tickets for this journey start at $35 (€29) but you can travel from only $33 (€27) by flight.
There are 4 buses per day. The earliest bus runs at 00:25, the last at 23:50. The fastest bus covers the 599 miles (964 km) distance in 16h 35m.
Distance 599 miles (964 km) |
Average bus duration 16h 26m |
Cheapest ticket price $35 (€29) |
Buses per day 12 |
Direct buses 4 |
Fastest bus 16h 35m |
First bus 12:25 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 21 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
Milan’s premier fine-art gallery, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
A leading museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist and modern collections.
A major design-forward museum for world cultures and blockbuster temporary exhibitions in the Tortona area.
Milan’s canal district, loved for waterside walks, lively atmosphere, and photogenic bridges and alleys.
A charming central neighborhood with elegant streets, galleries, boutiques, and a classic Milan atmosphere.
Milan’s main square and symbolic heart, framed by the cathedral, museums, and major historic buildings.
Creamy saffron risotto, one of Milan’s signature dishes, prized for its rich color and elegant flavor.
Braised veal shank, often served with risotto alla Milanese, a classic celebratory dish from Milanese cuisine.
Breaded veal cutlet fried until golden, a famous Milan specialty often compared with schnitzel but traditionally thicker.
Legendary casual stop near the Duomo, famous for panzerotti and a beloved institution for quick, affordable bites.
Well-known modern Milanese restaurant near Porta Nuova, celebrated for refined local classics in a stylish setting.
Historic trattoria serving traditional Milanese and Lombard dishes in an old-fashioned, atmospheric dining room.
Prices are high by Italian standards, especially for hotels and central dining, though transit and casual food stay manageable.
Tipping is modest. Service may be included. Round up or leave EUR 1-2 for coffee, 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
Orio al Serio Milan Bergamo Airport Bus Station, Bergamo -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Messina to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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