- Must visit
Musical Instruments Museum
Major museum in an Art Nouveau landmark with an outstanding collection of instruments from around the world and panoramic rooftop views.


Cheapest price
$146
Average price
$146
Fastest journey
20h 40m
Average duration
20h 53m
Buses per day
2
Distance
262 km
Omio recommends booking the flight as it is the most popular option from Manchester to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from $28. For those with little time consider booking a flight which can get you there in 2h 3m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.5 - 1.3kg. The ticket price range depends on the travel mode: a flight costs an average of $28, and a train costs an average of $399.
Distance: 333 miles (536 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$399 Average price | $121 Average price Cheapest | $122 Average price | $110 Average price (fuel + tolls) |
6h 48m Average total duration 6h 18m Onboard + 30m Additional time* | 5h 3m Average total duration Fastest 2h 3m Onboard + 3h 0m Additional time* | 15h 39m Average total duration 15h 9m Onboard + 30m Additional time* | 8h 18m Average total duration (door-to-door) |
- CO2 emissions | 1.6 - 3.2kg CO2 emissions | 0.5 - 1.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Manchester to Brussels:
A flight is $0.41 (€0.34) less than a bus for this route with tickets for a bus from Manchester to Brussels costing on average $122 (€100).
A flight is $277 (€228) less than a train for this route with tickets for a train from Manchester to Brussels costing on average $399 (€328).
Other travel options to Brussels take longer:
Train takes on average 6h 18m.
Bus takes on average 15h 9m.
You'll arrive about 2h 0m sooner (6h 18m by train vs 8h 18m by car). Tickets start at around $399 (€328) compared to roughly $110 (€90) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Manchester to Brussels trains for today, Sunday, July 12. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:56 PM Manchester | 13h09 | 10:05 AM Brussels | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Manchester to Brussels run on average 7 times per day, taking around 6h 18m. Cheap train tickets for this journey start at $399 (€328) but you can travel from only $28 (€23) by flight.
The earliest train runs at 05:05, the last at 17:50. The fastest train covers the 333 miles (536 km) distance in 5h 20m.
Distance 333 miles (536 km) |
Average train duration 6h 18m |
Cheapest ticket price $399 (€328) |
Trains per day 7 |
Fastest train 5h 20m |
First train 5:05 AM |
Last train 5:50 PM |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Fri |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Major museum in an Art Nouveau landmark with an outstanding collection of instruments from around the world and panoramic rooftop views.
Leading museum dedicated to René Magritte, presenting a large collection of surrealist works in the Royal Museums complex.
Flagship fine arts museums covering Flemish masters, Belgian art, and major temporary exhibitions in central Brussels.
Elegant 19th-century covered arcade lined with historic shops and cafes, popular for architecture, strolling, and photos.
Terraced garden and viewpoint with one of the most recognizable panoramas in central Brussels.
Stylish square known for antiques, architecture, and an upscale yet distinctly Brussels atmosphere.
Mussels steamed with white wine, celery, and herbs, served with fries. It is one of Belgium’s most iconic comfort dishes and a staple in Brussels brasseries.
A traditional Belgian beef and onion stew slowly cooked with dark Belgian beer, often slightly sweet-sour and served with fries or bread.
A rustic Brussels side dish of mashed potatoes mixed with vegetables such as carrots, leeks, or spinach, commonly served with sausage or meat dishes.
One of Brussels’ most famous fine dining institutions, celebrated for refined Belgian-French cuisine and elegant historic interiors.
Popular traditional restaurant known for generous Belgian comfort food, beer-based dishes, and an informal, bustling atmosphere.
Historic, long-running brasserie best known for moules-frites and classic Belgian dishes in a lively central setting.
Brussels is pricier than many Belgian cities. Hotels and dining add up, but transit and casual eats are manageable.
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for great service is appreciated. Round up taxi fares; small tips are optional at cafes and bars.
Official public transport app
Brussels-Midi, Brussels -> Brussels-Central, Brussels
Find answers to the most common questions about traveling from Manchester to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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