- Must visit
Centro Botín
Major contemporary art center on Santander’s waterfront, known for international exhibitions, cultural programming, and its striking Renzo Piano design.
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The cheapest and fastest buses from Lyon to Santander
Showing times and prices for Jun 19
Cheapest price
$65
Average price
$85
Fastest journey
19 h 20 m
Average duration
19 h 40 m
Buses per day
2
Distance
730 km
Cheap tickets
The best way to find a cheap bus ticket from Lyon to Santander is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Santander will cost around $85 if you buy it on the day, but the cheapest tickets can be found for only $65.
Fast buses
It's difficult to get from Lyon to Santander without transferring at least once.
Normal · Normal5:15 AM20h00Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:15 AMSantander, Estación de Autobuses$651One-way1 transfer
FlixBus · FlixBus · FlixBus2:00 PM19h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:20 AMSantander, Estación de Autobuses$1051One-way2 transfers
- FlixBus · FlixBus · FlixBus2:00 PM19h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:20 AMSantander, Estación de Autobuses$1051One-way2 transfers
- Normal · Normal5:15 AM20h00Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:15 AMSantander, Estación de Autobuses$651One-way1 transfer
Travel Information
Compare train, bus, and flight for Lyon to Santander
Omio recommends booking the bus as it is the most popular option from Lyon to Santander among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a flight which can get you there in 2h 55m. The ticket price range depends on the travel mode: a bus costs an average of $37, and a flight costs an average of $85.
Distance: 453 miles (730 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$79 Average price Cheapest | $324 Average price | $205 Average price | $308 Average price (fuel + tolls) |
16h 7m Average total duration 15h 37m Onboard + 30m Additional time* | 5h 55m Average total duration Fastest 2h 55m Onboard + 3h 0m Additional time* | 23h 13m Average total duration 22h 43m Onboard + 30m Additional time* | 9h 56m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Lyon to Santander is a bus with an average price of $79 (€65).
This is compared to other travel options from Lyon to Santander:
A bus is $126 (€103) less than a train for this route with tickets for a train from Lyon to Santander costing on average $205 (€168).
A bus is $245 (€201) less than a flight for this route with tickets for a flight from Lyon to Santander costing on average $324 (€266).
The fastest way to travel from Lyon to Santander is by flight with an average journey time of 2h 55m.
Other travel options to Santander take longer:
Bus takes on average 15h 37m.
Train takes on average 22h 43m.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Santander including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from Lyon to Santander among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Lyon to Santander Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Alsa | Departure Time 05:15AM | Arrival Time 01:15AM | Duration 20h00 | Departure days Everyday | Cheapest price $54 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 09:20AM | Duration 23h20 | Departure days Wed | Cheapest price $74 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 09:20AM | Duration 19h20 | Departure days Mon, Fri, Sun | Cheapest price $102 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 09:20AM | Duration 18h05 | Departure days Tue, Thu, Sat | Cheapest price $90 |
Live departures
Lyon to Santander bus times
The table below shows live departures for Lyon to Santander buses for tomorrow, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| Normal · Normal | 5:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h00 | 1:15 AM Santander, Estación de Autobuses | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 2:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h20 | 9:20 AM Santander, Estación de Autobuses | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Santander by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Lyon to Santander buses with Omio?
Alsa as well as FlixBus or BlaBlaCar Bus offer buses services from Lyon to Santander.
Omio is an official ticket reseller for all your travel options from Lyon to Santander.
Why book with Omio vs Alsa?
- Compare with other providers: On Omio, you can not only buy tickets for Alsa, but also compare tickets for the likes of FlixBus or BlaBlaCar Bus to find the best option for your trip from Lyon to Santander.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Alsa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon to Santander.
Why book with Omio over Checkmybus, Rome2rio or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or BlaBlaCar Bus to find the best option for your trip from Lyon to Santander.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon to Santander.
Journey information
Overview: Bus from Lyon to Santander
France
Spain
Buses from Lyon to Santander run on average 2 times per day, taking around 15h 37m. Cheap bus tickets for this journey start at $37 (€30) if you book in advance.
The earliest bus runs at 01:00, the last at 20:50. The fastest bus covers the 453 miles (730 km) distance in 17h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 453 miles (730 km) |
Average bus duration 15h 37m |
Cheapest ticket price $37 (€30) |
Buses per day 2 |
Fastest bus 17h 30m |
First bus 1:00 AM |
Last bus 8:50 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 35 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Alsa, FlixBus, BlaBlaCar Bus from Lyon to SantanderYou can travel by bus between Lyon to Santander with Alsa, FlixBus, BlaBlaCar Bus for as low as $37 (€30). When you search for schedules and tickets, Omio will show you the best journey
Alsa
About
Alsa is the main provider of bus travel in Spain and a subsidiary of the UK’s National Express. It operates an extensive network of regional, national, and international routes, transporting more than 300 million passengers annually. Alsa’s modern fleet offers varying levels of comfort and amenities. The standard Alsa Normal buses include free Wi-Fi, onboard bathrooms, footrests, and entertainment. For a more premium experience, Alsa Supra, Alsa Eurobus, and Alsa Premium services provide enhanced comfort and luxury features.
Luggage & cancellation policy
Average Duration
19h 35m
Cheapest Price
$37 (€30)
Alsa frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 25kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating.
Bikes
Bikes are allowed for an additional fee; must be packed.
Pets
Small pets allowed in carriers; larger pets must travel in the hold.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
17h 30m
Cheapest Price
$83 (€68)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
20h 0m
Cheapest Price
$87 (€71)
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
Complete guide to Santander
Things to do in Santander
Discover the best of Santander — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santander trip today.
- Must visit
Museo de Prehistoria y Arqueología de Cantabria
Important archaeological museum presenting prehistoric cave culture, Roman material, and key finds from across Cantabria.
- Recommended
Museo Marítimo del Cantábrico
Leading maritime museum covering Cantabrian Sea ecology, fishing, naval history, and aquariums; a strong family-friendly cultural stop.
- Must visit
Península de la Magdalena
Scenic headland combining gardens, sea views, beaches, and the palace grounds; ideal for walking and one of the city’s top experiences.
- Must visit
Playa del Sardinero
Santander’s best-known beach area, famous for its elegant promenade, broad sands, and lively atmosphere in good weather.
- Must visit
Paseo de Pereda
Grand waterfront promenade lined with historic buildings, sculptures, and access to the bay; essential for a first walk through Santander.
Rabas
Lightly battered and fried squid rings, one of Santander’s most iconic tapas, especially popular for aperitif time by the bay.
- Gluten-free
Anchoas de Santoña
High-quality Cantabrian anchovies, usually served in olive oil on bread or as a tapa; a flagship product of the region.
- Gluten-free
Bonito del Norte
White tuna from the Cantabrian Sea, prized for its delicate texture and often served grilled, stewed, or preserved in olive oil.
El Serbal
Michelin-starred restaurant known for contemporary tasting menus rooted in Cantabrian products, with polished service and elegant ambiance.
Cañadío
Well-known Santander restaurant and tapas bar, famous for refined Cantabrian cuisine, seafood, and a lively central atmosphere.
Bodega del Riojano
Historic and established dining room serving classic Cantabrian dishes in a traditional setting with strong local character.
Euro
Moderate by Spanish standards: tapas and set lunches are affordable, while waterfront dining and summer stays cost more.
Average meal costs
- Budget
- EUR 10-15 for a simple meal or tapas.
- Mid-range
- EUR 20-35 per person at a mid-range restaurant.
- Fine dining
- EUR 50-90 per person at upscale restaurants.
- Coffee
- EUR 1.50-3 for coffee.
Tipping culture
Tipping is modest. Round up or leave 5-10% in restaurants for good service. Small change in cafes is enough. Taxis are usually rounded up, and hotel tips are appreciated but not expected.
Moovit
Get the appOfficial public transport app
Prices
- Single ticket
- 1.30 EUR
- Day pass
- None
To the city center
Santander, Estación de Autobuses -> Santander Centro
- Distance
- 0.8 km
- Travel time
- 10 min
- On TUS city buses, the standard single ticket is 1.30 EUR and fares are managed by the municipal operator. Check service updates on the official TUS Santander website.
- Card payment availability on Santander city buses is not consistently confirmed across official sources, so carry cash or a rechargeable transport card for convenience.
FAQs: Bus from Lyon to Santander
Find answers to the most common questions about traveling from Lyon to Santander by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Lyon to Santander can start from as little as $37 (€30) when you book in advance. The average bus ticket price for Lyon to Santander is $79 (€65) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Lyon to Santander is 17h 30m to travel the 453 miles (730 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Lyon to Santander leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Lyon to Santander leaves at 8:50 PM.
There are 2 buses a day from Lyon to Santander which require at least one change with Alsa, FlixBus, BlaBlaCar Bus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Lyon to Santander, you can count on Alsa, FlixBus, BlaBlaCar Bus for the best way to get you to Santander. You can also check all possible bus companies who offer a service between Lyon and Santander and compare the amenities they offer before buying a bus ticket.
When departing from Lyon , you have various bus station options to start your journey from including Lyon, Perrache Bus Station, Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), Lyon, St Exupéry Aéroport, Lyon, Givors, Plaza Jean Berry . When arriving in Santander , you can end your journey in bus stations like Santander, Estación de Autobuses .Passengers board the bus most frequently from Lyon, Perrache Bus Station, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Santander, Estación de Autobuses, located 0 away from the city centre.
A trip to Santander from Lyon is worth doing but not as a day trip with a journey time of 17h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Lyon to Santander is September.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Santander including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Lyon to Santander:
- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Lyon to Santander for bus company Alsa, FlixBus, BlaBlaCar Bus.
Some of the most interesting sights to explore in Santander are:
- Palacio de la Magdalena, a historic royal palace set on a peninsula offering stunning views and guided tours
- Centro Botín, a modern art center designed by Renzo Piano featuring exhibitions and cultural events
- Playa del Sardinero, a popular beach known for its golden sands and vibrant promenade
- Museo Marítimo del Cantábrico, a maritime museum showcasing marine life and naval history
- Jardines de Piquío, beautifully landscaped gardens offering a peaceful retreat with ocean views.
The best things to do in Santander include:
- Santander Cathedral, a Gothic-style cathedral with impressive architecture and historical significance
- Parque de Mataleñas, a scenic park ideal for hiking and enjoying nature
- Mercado de la Esperanza, a bustling market where you can experience local culture and cuisine
- Paseo de Pereda, a picturesque promenade perfect for a leisurely stroll along the waterfront
- Gran Casino del Sardinero, a historic casino offering entertainment and a glimpse into the city's glamorous past.
Whether you can cancel your bus ticket from Lyon to Santander depends on the bus companies:
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Alsa, FlixBus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Lyon to Santander.
Yes, the following luggage options are included when booking a bus ticket from Lyon to Santander:
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Lyon to Santander:
- Alsa
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Lyon to Santander. The following conditions apply:
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Lyon to Santander with the following bus company: Alsa, FlixBus, BlaBlaCar Bus
Yes, there are USB plugs on board the bus from Lyon to Santander with the following bus company: Alsa, FlixBus, BlaBlaCar Bus.
Yes, there is Wifi on board the bus from Lyon to Santander with the following bus company: Alsa, FlixBus, BlaBlaCar Bus.
Since both Lyon and Santander are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Lyon to Santander among Omio's users.
Spain uses the euro (€) as its currency. Travelers can use both cash and cards, but cards are widely accepted in cities and tourist areas, while cash may be preferred for small purchases, markets, and rural locations.
In Santander, travelers should be cautious of pickpocketing, especially in crowded areas such as public transport and popular tourist spots. Scams involving overcharging or unofficial taxi services can occur, so it's recommended to use licensed taxis and agree on fares beforehand. Additionally, travelers should be wary of distraction techniques used by thieves in busy markets or near attractions. Staying alert and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Lyon to Santander
Lyon
Santander
The major bus station for departures in Lyon is Lyon, Gare Routière de Perrache. Find all the information you need to know about services, amenities and connections at Lyon, Gare Routière de Perrache for your trip from Lyon to Santander.
Lyon, Gare Routière de Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 km
Car connection
Cours de VerdunWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
Taxis
- Available outside the main entrance
Accessibility
- Elevators, ramps
WC
- Available in the station
Public transit options for Lyon, Gare Routière de Perrache
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
information
Lyon, St Exupéry Aéroport
information
The major bus station for arrivals in Santander is Santander, Estación de Autobuses. Find all the information you need to know about services, amenities and connections at Santander, Estación de Autobuses for your trip to Santander from Lyon.
Santander, Estación de Autobuses
information
Most popular bus connections from Lyon
More options for your journey from Lyon to Santander
Here are some other resources that might have the information you need
Most popular buses to and from Santander and Lyon
Most popular bus connections to Santander
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