- Must visit
National Museum
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
Cheapest price
$75
Average price
$75
Fastest journey
15 h 50 m
Average duration
15 h 50 m
Buses per day
1
Distance
848 km
The best way to find a cheap bus ticket from Lyon Saint Exupery Airport to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon Saint Exupery Airport to Prague will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $75.
Of the 1 buses that leave Lyon Saint Exupery Airport for Prague on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 848 km distance in an average of 15 h 50 m but if you time it right, some buses will get you there in just 15 h 50 m .
On Sun, Jun 21 the slowest buses will take 15 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from Lyon Saint Exupery Airport to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $64. For those with little time consider booking a flight which can get you there in 2h 5m. The ticket price range depends on the travel mode: a bus costs an average of $64, and a flight costs an average of $56.
Distance: 526 miles (848 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$81 Average price Cheapest | $169 Average price | $266 Average price (fuel + tolls) |
16h 33m Average total duration 16h 3m Onboard + 30m Additional time* | 5h 5m Average total duration Fastest 2h 5m Onboard + 3h 0m Additional time* | 11h 17m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon Saint Exupery Airport to Prague:
A bus is $88 (€72) less than a flight for this route with tickets for a flight from Lyon Saint Exupery Airport to Prague costing on average $169 (€139).
Other travel options to Prague take longer:
Bus takes on average 16h 3m.
Tickets start at around $81 (€67) compared to roughly $266 (€218) in fuel and tolls — a saving of about $185 (€151). The journey takes 16h 3m versus 11h 17m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:25AM | Arrival Time 01:50AM | Duration 24h25 | Departure days Wed | Cheapest price $103 |
Operator FlixBus | Departure Time 03:20AM | Arrival Time 10:25PM | Duration 19h05 | Departure days Mon, Tue, Fri, Sat | Cheapest price $71 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 11:25PM | Duration 19h05 | Departure days Mon | Cheapest price $66 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 11:45AM | Duration 24h40 | Departure days Wed | Cheapest price $64 |
Operator FlixBus | Departure Time 01:10PM | Arrival Time 08:20AM | Duration 19h10 | Departure days Wed | Cheapest price $86 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 07:20AM | Duration 16h20 | Departure days Thu | Cheapest price $111 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 06:55AM | Duration 15h50 | Departure days Sat | Cheapest price $90 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 07:55AM | Duration 15h50 | Departure days Mon, Fri, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 08:20AM | Duration 15h05 | Departure days Mon | Cheapest price $81 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 02:10PM | Duration 18h10 | Departure days Wed | Cheapest price $75 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 01:35PM | Duration 17h05 | Departure days Tue | Cheapest price $78 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 03:10PM | Duration 18h10 | Departure days Fri | Cheapest price $78 |
The table below shows live departures for Lyon Saint Exupery Airport to Prague buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:05 PM Lyon Saint Exupery Airport | 15h50 | 6:55 AM Prague | 0 transfersDirect | |
![]() | 4:05 PM Lyon Saint Exupery Airport | 15h50 | 7:55 AM Prague | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lyon Saint Exupery Airport to Prague run on average 9 times per day, taking around 16h 3m. Cheap bus tickets for this journey start at $64 (€52) but you can travel from only $56 (€46) by flight.
There are 4 buses per day. The earliest bus runs at 01:25, the last at 21:00. The fastest bus covers the 526 miles (848 km) distance in 15h 5m.
Distance 526 miles (848 km) |
Average bus duration 16h 3m |
Cheapest ticket price $64 (€52) |
Buses per day 9 |
Direct buses 4 |
Fastest bus 15h 5m |
First bus 1:25 AM |
Last bus 9:00 PM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Sun |
Least Busy Day Sun |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
A significant museum complex preserving Jewish history and heritage through synagogues, ceremonial objects, and exhibitions in Josefov.
A highly regarded design museum with glass, ceramics, fashion, graphics, and decorative arts in a historic building near the Old Town.
Prague’s ceremonial heart, surrounded by historic facades, churches, and major landmarks; essential for first-time visitors.
A picturesque historic district below Prague Castle with baroque streets, embassies, gardens, and a romantic atmosphere.
A major boulevard-like square central to modern Czech history, shopping, and public life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the best-known classic Czech festive dishes.
Roast pork served with dumplings and braised cabbage. This is a cornerstone of traditional Czech home-style cooking and pub menus.
Czech-style goulash is usually a rich beef stew with onions, paprika, and bread dumplings. It is a hearty staple often eaten in historic Prague pubs.
Established traditional restaurant known for duck, old-Bohemian recipes, and elegant historic interiors. A strong choice for a refined Czech meal.
Well-known Old Town restaurant offering polished Czech classics and seasonal dishes in a stylish but approachable atmosphere.
A famous modern Czech beer hall serving classic dishes, fresh Pilsner, and dependable traditional cooking in a lively central setting.
Moderate by European standards. Beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip needed for counter service, though small change is appreciated.
Official public transport app
Praha Hlavní Nádraží, Prague -> Václavské Náměstí, Prague
Find answers to the most common questions about traveling from Lyon Saint Exupery Airport to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Lyon Saint Exupery Airport to Prague buses use the Lyon, Gare Routière de Perrache to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Lyon Saint Exupery Airport and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need