- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price
$46
Average price
$62
Fastest journey
10 h 45 m
Average duration
13 h 4 m
Buses per day
4
Distance
573 km
The best way to find a cheap bus ticket from Lyon Saint Exupery Airport to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon Saint Exupery Airport to Brussels will cost around $62 if you buy it on the day, but the cheapest tickets can be found for only $46.
Of the 4 buses that leave Lyon Saint Exupery Airport for Brussels on Thu, Aug 06, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct buses cover the 573 km distance in an average of 13 h 4 m but if you time it right, some buses will get you there in just 10 h 45 m .
On Thu, Aug 06 the slowest buses will take 18 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Buses from Lyon Saint Exupery Airport to Brussels run on average 7 times per day, taking around 11h 38m. Cheap bus tickets for this journey start at $42 if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:40, the last at 23:50. The fastest bus covers the 356 miles (573 km) distance in 10h 45m.
Distance 356 miles (573 km) |
Average bus duration 11h 38m |
Cheapest ticket price $42 |
Buses per day 7 |
Direct buses 1 |
Fastest bus 10h 45m |
First bus 12:40 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Fri |
Least Busy Day Fri |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:40AM | Arrival Time 02:50PM | Duration 14h10 | Departure days Fri | Cheapest price $66 |
Operator FlixBus | Departure Time 12:45AM | Arrival Time 02:50PM | Duration 14h05 | Departure days Sun | Cheapest price $95 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 01:45PM | Duration 10h45 | Departure days Wed, Thu | Cheapest price $88 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 03:55PM | Duration 12h25 | Departure days Tue | Cheapest price $58 |
Operator FlixBus | Departure Time 04:25AM | Arrival Time 04:55PM | Duration 12h30 | Departure days Mon | Cheapest price $54 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 07:35PM | Duration 12h25 | Departure days Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 08:10AM | Arrival Time 08:35PM | Duration 12h25 | Departure days Sat | Cheapest price $62 |
Operator FlixBus | Departure Time 11:30AM | Arrival Time 10:35PM | Duration 11h05 | Departure days Mon | Cheapest price $70 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 07:15AM | Duration 18h45 | Departure days Thu | Cheapest price $46 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 02:05AM | Duration 11h50 | Departure days Tue, Fri | Cheapest price $54 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 07:15AM | Duration 16h45 | Departure days Wed | Cheapest price $45 |
Operator BlaBlaCar Bus | Departure Time 05:20PM | Arrival Time 04:20AM | Duration 11h00 | Departure days Mon, Fri, Sat | Cheapest price $42 |
Operator BlaBlaCar Bus | Departure Time 05:45PM | Arrival Time 06:00AM | Duration 12h15 | Departure days Sat, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 07:25PM | Arrival Time 06:15AM | Duration 10h50 | Departure days Wed | Cheapest price $75 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 04:55PM | Duration 21h25 | Departure days Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 07:15AM | Duration 10h50 | Departure days Wed, Thu, Sat | Cheapest price $48 |
Operator FlixBus | Departure Time 10:10PM | Arrival Time 10:20AM | Duration 12h10 | Departure days Thu | Cheapest price $140 |
Operator FlixBus | Departure Time 10:50PM | Arrival Time 10:45AM | Duration 11h55 | Departure days Wed | Cheapest price $51 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 11:45AM | Duration 11h55 | Departure days Sat | Cheapest price $59 |
The table below shows live departures for Lyon Saint Exupery Airport to Brussels buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:30 PM Lyon Saint Exupery Airport | 16h45 | 7:15 AM Brussels | 0 transfersDirect | |
![]() | 7:25 PM Lyon Saint Exupery Airport | 10h50 | 6:15 AM Brussels | 0 transfersDirect | |
![]() | 8:25 PM Lyon Saint Exupery Airport | 10h50 | 7:15 AM Brussels | 0 transfersDirect | |
| Thursday, August 6 | |||||
![]() | 3:00 AM Lyon Saint Exupery Airport | 10h45 | 1:45 PM Brussels | 0 transfersDirect | |
![]() | 12:30 PM Lyon Saint Exupery Airport | 18h45 | 7:15 AM Brussels | 0 transfersDirect | |
Find all the dates and times for this journey
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Lyon Saint Exupery Airport to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Lyon Saint Exupery Airport to Brussels buses use the Lyon, Gare Routière de Perrache to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord). Use this guide to compare Lyon Saint Exupery Airport and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Brussels-Noord.
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
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