- Must visit
Greensboro Science Center
A popular family-friendly complex combining an aquarium, museum, and zoo, known for interactive exhibits and broad appeal.
Cheapest price
$136
Average price
$137
Fastest journey
11 h 45 m
Average duration
11 h 45 m
Buses per day
2
Distance
355 km
The best way to find a cheap bus ticket from North Charleston, SC to Greensboro, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from North Charleston, SC to Greensboro, NC will cost around $137 if you buy it on the day, but the cheapest tickets can be found for only $136.
Of the 2 buses that leave North Charleston, SC for Greensboro, NC on Fri, Jun 19, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 355 km distance in an average of 11 h 45 m but if you time it right, some buses will get you there in just 11 h 45 m .
On Fri, Jun 19 the slowest buses will take 11 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from North Charleston, SC to Greensboro, NC among Omio's users. If you are prioritising price take the bus with prices starting from $84. For those with little time consider booking a flight which can get you there in 6h 24m. The ticket price range depends on the travel mode: a bus costs an average of $84, and a flight costs an average of $309.
Distance: 220 miles (355 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$121 Average price Cheapest | $167 Average price | $461 Average price |
12h 27m Average total duration 11h 57m Onboard + 30m Additional time* | 8h 0m Average total duration 7h 30m Onboard + 30m Additional time* | 9h 24m Average total duration Fastest 6h 24m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from North Charleston, SC to Greensboro, NC:
A bus is $45 (€37) less than a train for this route with tickets for a train from North Charleston, SC to Greensboro, NC costing on average $167 (€136).
A bus is $339 (€277) less than a flight for this route with tickets for a flight from North Charleston, SC to Greensboro, NC costing on average $461 (€376).
Other travel options to Greensboro, NC take longer:
Train takes on average 7h 30m.
Bus takes on average 11h 57m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:15PM | Arrival Time 03:00AM | Duration 11h45 | Departure days Tue, Thu, Fri, Sun | Cheapest price $92 |
Operator Greyhound | Departure Time 04:15PM | Arrival Time 04:00AM | Duration 11h45 | Departure days Mon, Tue, Wed, Fri, Sat | Cheapest price $84 |
The table below shows live departures for North Charleston, SC to Greensboro, NC buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:15 PM North Charleston, SC | 11h45 | 3:00 AM Greensboro, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from North Charleston, SC to Greensboro, NC run on average 1 times per day, taking around 11h 57m. Cheap bus tickets for this journey start at $84 (€68) if you book in advance.
The earliest bus runs at 11:15, the last at 23:10. The fastest bus covers the 220 miles (355 km) distance in 11h 45m.
Distance 220 miles (355 km) |
Average bus duration 11h 57m |
Cheapest ticket price $84 (€68) |
Buses per day 1 |
Fastest bus 11h 45m |
First bus 11:15 AM |
Last bus 11:10 PM |
Cheapest Month Jan |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Greensboro — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greensboro trip today.
A popular family-friendly complex combining an aquarium, museum, and zoo, known for interactive exhibits and broad appeal.
A nationally significant museum at the former Woolworth building, interpreting the Greensboro sit-ins and the civil rights movement.
The university art museum with a strong modern and contemporary collection, widely regarded as one of the city’s best cultural stops.
The city’s main walkable core, mixing historic blocks, murals, theaters, museums, and nightlife-oriented public spaces.
A large historic park with trails, monuments, and interpretive stops, combining outdoor walking with Revolutionary War history.
A landscaped public garden with seasonal color, sculptures, and easy paths, popular for photos and quiet walks.
Slow-smoked pork shoulder chopped or pulled and dressed in a tangy vinegar-based sauce, a classic Piedmont and statewide barbecue tradition.
A regional red slaw made with cabbage and a lightly sweet vinegar-tomato dressing, commonly served on barbecue sandwiches across central North Carolina.
Fluffy Southern biscuits filled with salty cured ham, a breakfast staple in North Carolina and a familiar comfort food in Greensboro.
A popular casual spot recognized for creative burgers, good beer selection, and lively neighborhood energy.
A polished bistro at Proximity Hotel known for seasonal American fare, strong brunch, and an upscale yet relaxed setting.
An established restaurant offering European-influenced American cuisine, dependable service, and a refined dining room popular for dinner and brunch.
Costs are generally moderate for U.S. travel, with affordable dining and parking, while hotels vary by season and events.
Tip 18-20% at restaurants; 20%+ for excellent service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from North Charleston, SC to Greensboro, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greensboro, NC, this guide helps you travel smarter and with confidence.

Most North Charleston, SC to Greensboro, NC buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Greensboro, E Washington St (Greyhound Bus Station) station pair. Use this guide to compare North Charleston, SC and Greensboro, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need