- Must visit
Vatican Museums
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
Cheapest price
$24
Average price
$24
Fastest journey
5 h 45 m
Average duration
5 h 45 m
Buses per day
2
Distance
399 km
The best way to find a cheap bus ticket from Cassano All’Ionio to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Cassano All’Ionio to Rome will cost around $24 if you buy it on the day, but the cheapest tickets can be found for only $24.
Of the 2 buses that leave Cassano All’Ionio for Rome on Wed, Jul 01, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 01 the direct buses cover the 399 km distance in an average of 5 h 45 m but if you time it right, some buses will get you there in just 5 h 45 m .
On Wed, Jul 01 the slowest buses will take 5 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Cassano All’Ionio to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $17. For those with little time consider booking a flight which can get you there in 1h 14m. The ticket price range depends on the travel mode: a bus costs an average of $17, and a flight costs an average of $81.
Distance: 247 miles (399 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$31 Average price Cheapest | $173 Average price | $51 Average price | $92 Average price (fuel + tolls) |
6h 27m Average total duration 5h 57m Onboard + 30m Additional time* | 4h 14m Average total duration Fastest 1h 14m Onboard + 3h 0m Additional time* | 9h 48m Average total duration 9h 18m Onboard + 30m Additional time* | 4h 38m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Cassano All’Ionio to Rome:
A bus is $20 (€16) less than a train for this route with tickets for a train from Cassano All’Ionio to Rome costing on average $51 (€42).
A bus is $142 (€117) less than a flight for this route with tickets for a flight from Cassano All’Ionio to Rome costing on average $173 (€142).
Other travel options to Rome take longer:
Bus takes on average 5h 57m.
Train takes on average 9h 18m.
Tickets start at around $31 (€25) compared to roughly $92 (€75) in fuel and tolls — a saving of about $61 (€50). The journey takes 5h 57m versus 4h 38m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Itabus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:25AM | Arrival Time 11:40AM | Duration 5h15 | Departure days Fri | Cheapest price $26 |
Operator Marino Autolinee | Departure Time 07:10AM | Arrival Time 12:35PM | Duration 5h25 | Departure days Mon | Cheapest price $34 |
Operator Itabus | Departure Time 12:10PM | Arrival Time 05:55PM | Duration 5h45 | Departure days Wed, Thu, Fri, Sat | Cheapest price $17 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 06:10PM | Duration 5h15 | Departure days Sun | Cheapest price $59 |
Operator Itabus | Departure Time 01:10PM | Arrival Time 06:55PM | Duration 5h45 | Departure days Wed | Cheapest price $24 |
Operator FlixBus | Departure Time 01:55PM | Arrival Time 07:10PM | Duration 5h15 | Departure days Thu | Cheapest price $17 |
Operator FlixBus | Departure Time 10:20PM | Arrival Time 03:35AM | Duration 5h15 | Departure days Fri | Cheapest price $27 |
Operator Marino Autolinee | Departure Time 11:05PM | Arrival Time 04:30AM | Duration 5h25 | Departure days Sun | Cheapest price $32 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Cassano All’Ionio to Rome run on average 12 times per day, taking around 5h 57m. Cheap bus tickets for this journey start at $17 (€14) if you book in advance.
There are 11 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 247 miles (399 km) distance in 5h 15m.
Distance 247 miles (399 km) |
Average bus duration 5h 57m |
Cheapest ticket price $17 (€14) |
Buses per day 12 |
Direct buses 11 |
Fastest bus 5h 15m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 56 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
A celebrated villa museum with major works by Bernini, Caravaggio, and Canova, set inside Villa Borghese gardens. Timed-entry tickets are required and usually need advance reservation.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, sculpture, paintings, and superb views over the Forum area.
A grand Baroque square lined with fountains, churches, and elegant facades. It remains one of Rome’s classic walking and people-watching spots.
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti, popular for photos, shopping nearby, and city atmosphere.
A characterful district of narrow lanes, ivy-covered facades, and lively evening atmosphere, widely loved for wandering and street photography.
A classic Roman pasta with Pecorino Romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, Pecorino Romano, and black pepper. It is a defining dish of Rome and should not contain cream.
Pasta with tomato, guanciale, Pecorino Romano, and chili. Though linked with Amatrice, it is a staple on Roman menus and deeply rooted in local cooking.
A historic trattoria near the Pantheon, respected for traditional Roman dishes such as carbonara, amatriciana, and seasonal specialties in an intimate atmosphere.
A celebrated central Rome dining room and delicatessen known for classic Roman pasta, cured meats, and an exceptional wine list in a lively upscale setting.
A famous Trastevere trattoria known for authentic Roman comfort food, including cacio e pepe, meatballs, and artichokes, with a classic casual feel.
Moderate for Western Europe: food and coffee can be reasonable, but hotels and major tourist areas cost more.
Service is often included or modest. Locals may round up or leave EUR 1-2 for coffee, 5-10% for good restaurant service; tips are appreciated, not required.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Cassano All’Ionio to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Cassano All’Ionio to Rome buses use the Frascineto, SP263 (Ristorante IL Baffo) to Roma, Autostazione Tiburtina station pair, with some services arriving at Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine". Use this guide to compare Cassano All’Ionio and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need