- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
Cheapest price
$44
Average price
$57
Fastest journey
8 h 15 m
Average duration
9 h 45 m
Buses per day
5
Distance
458 km
The best way to find a cheap bus ticket from Alessandria to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Alessandria to Rome will cost around $57 if you buy it on the day, but the cheapest tickets can be found for only $44.
Of the 5 buses that leave Alessandria for Rome on Sat, Jun 20, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 458 km distance in an average of 9 h 45 m but if you time it right, some buses will get you there in just 8 h 15 m .
On Sat, Jun 20 the slowest buses will take 11 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Omio recommends booking the train as it is the most popular option from Alessandria to Rome among Omio's users. If you are prioritising price take the train with prices starting from $26. For those with little time consider booking a flight which can get you there in 1h 17m. The ticket price range depends on the travel mode: a train costs an average of $26, and a flight costs an average of $50.
Distance: 284 miles (458 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$58 Average price | $58 Average price Cheapest | $107 Average price | $164 Average price (fuel + tolls) |
8h 46m Average total duration 8h 16m Onboard + 30m Additional time* | 6h 16m Average total duration 5h 46m Onboard + 30m Additional time* | 4h 17m Average total duration Fastest 1h 17m Onboard + 3h 0m Additional time* | 6h 26m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Alessandria to Rome:
A train is $0.29 (€0.24) less than a bus for this route with tickets for a bus from Alessandria to Rome costing on average $58 (€48).
A train is $49 (€40) less than a flight for this route with tickets for a flight from Alessandria to Rome costing on average $107 (€88).
Other travel options to Rome take longer:
Train takes on average 5h 46m.
Bus takes on average 8h 16m.
Tickets start at around $58 (€48) compared to roughly $164 (€134) in fuel and tolls — a saving of about $105 (€86). The journey takes 8h 16m versus 6h 26m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, Busitalia, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:30AM | Arrival Time 04:05PM | Duration 11h35 | Departure days Mon, Tue, Sat | Cheapest price $40 |
Operator FlixBus | Departure Time 05:30AM | Arrival Time 05:05PM | Duration 11h35 | Departure days Mon, Sat | Cheapest price $30 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 06:05PM | Duration 11h35 | Departure days Wed, Thu, Fri, Sun | Cheapest price $53 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 01:30PM | Duration 6h30 | Departure days Wed | Cheapest price $44 |
Operator BlaBlaCar | Departure Time 07:10AM | Arrival Time 01:50PM | Duration 6h40 | Departure days Wed | Cheapest price $47 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 03:20PM | Duration 6h10 | Departure days Wed | Cheapest price $50 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 04:10PM | Duration 6h10 | Departure days Fri | Cheapest price $68 |
Operator BlaBlaCar | Departure Time 12:50PM | Arrival Time 06:40PM | Duration 5h50 | Departure days Wed | Cheapest price $68 |
Operator Busitalia | Departure Time 02:20PM | Arrival Time 09:59PM | Duration 7h39 | Departure days Tue | Cheapest price $54 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 10:20PM | Duration 7h50 | Departure days Fri | Cheapest price $50 |
Operator Busitalia | Departure Time 03:20PM | Arrival Time 10:59PM | Duration 7h39 | Departure days Tue | Cheapest price $54 |
Operator Marino Autolinee | Departure Time 05:25PM | Arrival Time 02:30AM | Duration 9h05 | Departure days Mon, Sat | Cheapest price $57 |
Operator BlaBlaCar | Departure Time 07:00PM | Arrival Time 01:30AM | Duration 6h30 | Departure days Fri | Cheapest price $69 |
Operator Marino Autolinee | Departure Time 07:25PM | Arrival Time 04:30AM | Duration 9h05 | Departure days Wed, Thu, Fri, Sun | Cheapest price $61 |
Operator FlixBus | Departure Time 08:45PM | Arrival Time 05:00AM | Duration 8h15 | Departure days Mon, Tue, Sat | Cheapest price $51 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 06:00AM | Duration 8h15 | Departure days Mon, Sat | Cheapest price $53 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 07:00AM | Duration 8h15 | Departure days Wed, Thu, Fri, Sun | Cheapest price $61 |
The table below shows live departures for Alessandria to Rome buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 6:30 AM Alessandria, Piazzale Curiel (stazione FS) | 11h35 | 6:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
063 · 055 | 7:25 PM Alessandria, Piazzale Curiel (stazione FS) | 9h05 | 4:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 10:45 PM Alessandria, Piazzale Curiel (stazione FS) | 8h15 | 7:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Alessandria to Rome run on average 4 times per day, taking around 8h 16m. Cheap bus tickets for this journey start at $26 (€21) but you can travel from only $26 (€21) by train.
There are 2 buses per day. The earliest bus runs at 00:04, the last at 23:47. The fastest bus covers the 284 miles (458 km) distance in 7h 39m.
Distance 284 miles (458 km) |
Average bus duration 8h 16m |
Cheapest ticket price $26 (€21) |
Buses per day 4 |
Direct buses 2 |
Fastest bus 7h 39m |
First bus 12:04 AM |
Last bus 11:47 PM |
Cheapest Month Dec |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Thu |
Best time to book 7 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
One of Rome’s finest art museums, known for Bernini sculptures and paintings by Caravaggio and Raphael. Advance reservation is typically required because entry is strictly timed.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, imperial sculpture, and art with views over the Forum.
Elegant Baroque square built on an ancient stadium, lined with fountains, palaces, and lively street life. A classic area for strolling and people-watching.
Atmospheric neighborhood of narrow lanes, ivy-covered buildings, and busy evening streets. Popular with visitors but still one of Rome’s most characteristic areas.
Famous monumental staircase linking Piazza di Spagna and Trinità dei Monti. A highly photographed landmark and social-media favorite.
A classic Roman pasta with pecorino Romano and black pepper. It is one of the city’s most iconic dishes and a benchmark of Roman cooking.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is famous for its rich sauce without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino Romano, closely tied to Rome’s culinary identity and served with bucatini or rigatoni.
Rome’s most famous fine-dining restaurant, offering elegant tasting menus, panoramic views, and one of the city’s most prestigious dining experiences.
A historic trattoria near the Pantheon, famous for traditional Roman dishes such as gricia, amatriciana, and seasonal specialties.
A celebrated central Rome venue known for classic Roman pasta, exceptional cured meats, and a refined but lively atmosphere.
Rome is moderate by Western Europe standards: sights are affordable, but central hotels and tourist-area dining cost more.
Service is usually included or modest. Tipping is not required, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Alessandria to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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