Travel Information
Compare train, bus, and flight for Toulouse to Lyon
Omio recommends booking the bus as it is the most popular option from Toulouse to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a flight which can get you there in 2h 52m. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $62.
Distance: 223 miles (359 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$38 Average price Cheapest | $95 Average price | $142 Average price | $160 Average price (fuel + tolls) |
7h 12m Average total duration 6h 42m Onboard + 30m Additional time* | 5h 48m Average total duration 5h 18m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 2h 52m Onboard + 3h 0m Additional time* | 5h 31m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Toulouse to Lyon:
A bus is $56 (€46) less than a train for this route with tickets for a train from Toulouse to Lyon costing on average $95 (€78).
A bus is $103 (€85) less than a flight for this route with tickets for a flight from Toulouse to Lyon costing on average $142 (€117).
Other travel options to Lyon take longer:
Train takes on average 5h 18m.
Bus takes on average 6h 42m.
Travel optionsfrom Toulouse to Lyon
How to get from Toulouse to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Toulouse to Lyon is by taking a bus because it’s the best combination of price and speed.
31876:30 AM7h10Toulouse, Gare routière Pierre Semard (Matabiau)1:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$261One-way0 transfers
Cheapest
31876:30 AM7h10Toulouse, Gare routière Pierre Semard (Matabiau)1:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$261One-way0 transfers
Fastest
AF60276:10 PM1h00Toulouse Blagnac Airport7:10 PMLyon Saint Exupery Airport$7061One-way0 transfers
Other options
68755:41 PM3h57Gare de Toulouse-Matabiau9:38 PMLyon Part Dieu$601One-way0 transfers
68733:44 PM4h06Gare de Toulouse-Matabiau7:50 PMLyon Part Dieu$801One-way0 transfers
68717:39 AM4h09Gare de Toulouse-Matabiau11:48 AMLyon Part Dieu$1111One-way0 transfers
FlixBus6:40 AM6h50Toulouse, Gare routière Pierre Semard (Matabiau)1:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$281One-way0 transfers
FlixBus8:05 AM8h30Toulouse, Gare routière Pierre Semard (Matabiau)4:35 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$281One-way0 transfers
5108212:30 PM8h25Toulouse, Gare routière Pierre Semard (Matabiau)8:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$281One-way0 transfers
SN3676+
SN35876:50 AM5h35Toulouse Blagnac Airport12:25 PMLyon Saint Exupery Airport$4821One-way1 transfer
SN3668+
SN359312:10 PM10h10Toulouse Blagnac Airport10:20 PMLyon Saint Exupery Airport$4821One-way1 transfer
AF7421 · AF73626:05 AM3h25Toulouse Blagnac Airport9:30 AMLyon Saint Exupery Airport$4971One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Toulouse to Lyon
The Best Way According to our Users
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FAQs: Travel from Toulouse to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Toulouse to Lyon.

This is compared to other travel options from Toulouse to Lyon:
A bus is $56 (€46) less than a train for this route with tickets for a train from Toulouse to Lyon costing on average $95 (€78).
A bus is $103 (€85) less than a flight for this route with tickets for a flight from Toulouse to Lyon costing on average $142 (€117).
Other travel options to Lyon take longer:
Train takes on average 5h 18m.
Bus takes on average 6h 42m.
- Around 14 flights per day.
- Around 13 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Toulouse and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Toulouse Blagnac Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Gare de Toulouse-Matabiau and arrive in Lyon Part Dieu.
- Buses mostly depart from Toulouse, Gare routière Pierre Semard (Matabiau) and arrive in Lyon, Perrache Bus Station.
- Travel with easyJet, Air France to go to Lyon by flight.
- Travel with SNCF | TGV INOUI, SNCF | Intercités, SNCF TER | Operated by SNCF Voyageurs 1187, TGV, SNCF | Intercités de nuit, TER liO | Operated by SNCF Voyageurs 1187 to go to Lyon by train.
- Travel with BlaBlaCar Bus, FlixBus, Alsa, Internorte, BlaBlaCar to go to Lyon by bus.
- 1 direct flights per day with easyJet, Air France.
- 2 direct trains per day with SNCF | TGV INOUI.
- 9 direct buses per day with BlaBlaCar Bus, FlixBus, Alsa, Internorte, BlaBlaCar.
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