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Travel Information
Compare train, bus, and flight for Frankfurt am Main to Pisa
Omio recommends booking the bus as it is the most popular option from Frankfurt am Main to Pisa among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €90 For those with little time, consider booking a flight, which has an average total journey time of 4h 22m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.7 - 1.8kg. Average ticket prices depend on the travel mode: a bus costs an average of €90, while a flight costs an average of €225.
Distance: 449 miles (723 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
€90 Average price Cheapest | €225 Average price | €235 Average price (fuel + tolls) |
16h 39m Average total duration 16h 9m Onboard + 30m Additional time* | 4h 22m Average total duration Fastest 2h 22m Onboard + 2h 0m Additional time* | 10h 28m Average total duration (door-to-door) |
0.7 - 1.8kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | - CO2 emissions |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Pisa:
A bus is €135 less than a flight for this route with tickets for a flight from Frankfurt am Main to Pisa costing on average €225.
A bus is €235 less than a train for this route with tickets for a train from Frankfurt am Main to Pisa costing on average €325.
Other travel options to Pisa take longer:
Bus takes on average 16h 39m.
Train takes on average 20h 55m.
Tickets start at around €90 compared to roughly €235 in fuel and tolls — a saving of about €145. The journey takes 16h 9m versus 10h 28m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Frankfurt am Main to Pisa
How to get from Frankfurt am Main to Pisa by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Pisa is by taking a bus because it’s the best combination of price and speed.
- FlixBus · FlixBus12:45 AM20h50Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:35 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)€671One-way1 transfer
Cheapest
- FlixBus · FlixBus12:45 AM20h50Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:35 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)€671One-way1 transfer
Fastest
- FlixBus · FlixBus · FlixBus8:35 PM16h45Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)1:20 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)€691One-way2 transfers
Other options
FlixTrain+FlixBus · FlixBus8:03 PM17h17Frankfurt South station1:20 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)€681One-way2 transfers- FlixBus · FlixBus · FlixBus8:10 PM17h10Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)1:20 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)€691One-way2 transfers
- FlixBus · FlixBus · FlixBus5:55 AM18h55Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)12:50 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)€701One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Frankfurt am Main to Pisa
Travel to Pisa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Pisa.
This is compared to other travel options from Frankfurt am Main to Pisa:
A bus is €342 less than a flight for this route with tickets for a flight from Frankfurt am Main to Pisa costing on average €460.
Other travel options to Pisa take longer:
Bus takes on average 17h 31m.
- Around 9 flights per day.
- Around 9 buses per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Pisa as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Pisa International Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Pisa Centrale.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
- Travel with FlixBus to go to Pisa by bus.
- Travel with British Airways, Transavia France, Air Dolomiti to go to Pisa by flight.
- 3 direct flights per day with Air Dolomiti.
Travelling from Frankfurt am Main to Pisa: related information
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