Travel Information from Karlsruhe to Palermo
| 790 miles (1274 km) | |
| Train or bus | |
| $446 - $91 | |
| Bus • $91 (€82) • 31 h 35 min | |
| Train • $446 (€402) • 27 h 51 min | |
| FlixBus, Ryanair or Deutsche Bahn |
Travel 790 miles (1274 km) by train or bus to Palermo from Karlsruhe. The most popular travel companies which serve this trip are FlixBus, Ryanair or Deutsche Bahn among others. Travelers can even take a direct bus, flight or train from Karlsruhe to Palermo.
Travel optionsfrom Karlsruhe to Palermo
How to get from Karlsruhe to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Palermo is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBusCheapest
FlixBus · FlixBusFastest
ICE 78 · ICE 1012+
AZ7291 · AZ1771Other options
FlixTrain+
FlixBus · FlixBus
FlixBus · FlixBus
ICE 78 · ICE 1012+
AZ7291 · AZ1773
ICE 206+
AZ7291 · AZ1773
ICE 374 · ICE 614+
AZ7291 · AZ1773Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Karlsruhe to Palermo

There are 2 ways to get from Karlsruhe to Palermo: train or bus.
The cheapest way to get from Karlsruhe to Palermo is by taking a bus with average ticket prices of $91 (€82) compared to other travel options to Palermo:
Taking a bus costs () less than taking a flight, which costs on average () for the same trip.
A bus is $355 (€320) less than a train for this journey with tickets for a train from Karlsruhe to Palermo costing on average $446 (€402).
The fastest way to get to Palermo from Karlsruhe is by train with an average travel time of 27 h 51 min.
Other travel options to Palermo take longer:
Bus takes 31 h 35 min on average.
The Karlsruhe to Palermo distance is around 790 miles (1274 km).
The average frequency per day from Karlsruhe to Palermo is:
- 2 buses a day.
- Around 57 flights per day.
- 1 train per day.
However, we recommend checking specific travel dates for your journey from Karlsruhe to Palermo as scheduled services by train or bus can vary by season or day of the week.
These are the most popular departure and arrival points when traveling from Karlsruhe to Palermo:
The following travel companies offer services from Karlsruhe to Palermo:
- Travel with FlixBus for buses to Palermo. If you’re looking for a good deal on tickets, check for FlixBus Karlsruhe to Palermo tickets on Omio for $91 (€82).
- Ryanair can take you to Palermo by plane. If searching for a good deal on flights, you can find tickets for Ryanair from Karlsruhe to Palermo for $63 (€57).
- Deutsche Bahn can take you to Palermo by train. If searching for a good deal on trains, you can find tickets for Deutsche Bahn from Karlsruhe to Palermo for $446 (€402).
Yes, there are direct services available from Karlsruhe to Palermo with the following travel companies:
- Direct services by bus with.
- Direct services by plane with.
- Direct services by train with.
Direct services tend to save you time and add more convenience in getting you to Palermo as you won't need to transfer at another stop in between, so it's worth paying attention to before booking your tickets to Palermo from Karlsruhe.
Travelling from Karlsruhe to Palermo: related information
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