Travel Information
Compare train, bus, and flight for Karlsruhe to Palermo
Omio recommends booking the bus as it is the most popular option from Karlsruhe to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $98. For those with little time consider booking a train which can get you there in 30h 58m. The ticket price range depends on the travel mode: a bus costs an average of $98, and a train costs an average of $442.
Distance: 792 miles (1275 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$154 Average price Cheapest | $467 Average price |
36h 39m Average total duration 36h 9m Onboard + 30m Additional time* | 31h 28m Average total duration Fastest 30h 58m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Travel optionsfrom Karlsruhe to Palermo
How to get from Karlsruhe to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Palermo is by taking a bus because it’s the best combination of price and speed.
10:40 PM35h20Karlsruhe10:00 AMPalermo$1661One-way0 transfers
Cheapest
10:40 PM35h20Karlsruhe10:00 AMPalermo$1661One-way0 transfers
Fastest
10:40 PM35h20Karlsruhe10:00 AMPalermo$1661One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Karlsruhe to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Palermo.

This is compared to other travel options from Karlsruhe to Palermo:
A bus is $344 (€276) less than a train for this route with tickets for a train from Karlsruhe to Palermo costing on average $442 (€355).
Other travel options to Palermo take longer:
Bus takes on average 30h 45m.
- Around 4 buses per day.
- Around 1 flights per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Palermo as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from Karlsruhe Hbf and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Flights mostly depart from Karlsruhe/Baden-Baden Airport and arrive in Palermo Airport.
- Travel with Ryanair to go to Palermo by flight.
- Travel with FlixBus to go to Palermo by bus.
- Travel with Deutsche Bahn to go to Palermo by train.
Travelling from Karlsruhe to Palermo: related information
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