Travel Information
Compare train and bus for Karlsruhe to Avignon
Omio recommends booking the train as it is the most popular option from Karlsruhe to Avignon among Omio's users. If you are prioritising price take the bus with prices starting from $40. For those with little time consider booking a train which can get you there in 5h 59m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $40, and a train costs an average of $75.
Distance: 388 miles (625 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$164 Average price | $59 Average price Cheapest | $223 Average price (fuel + tolls) |
6h 29m Average total duration Fastest 5h 59m Onboard + 30m Additional time* | 11h 23m Average total duration 10h 53m Onboard + 30m Additional time* | 8h 11m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 0.6 - 1.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Avignon:
A bus is $105 (€86) less than a train for this route with tickets for a train from Karlsruhe to Avignon costing on average $164 (€134).
Other travel options to Avignon take longer:
Bus takes on average 10h 53m.
Travel optionsfrom Karlsruhe to Avignon
How to get from Karlsruhe to Avignon by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Avignon is by taking a bus because it’s the best combination of price and speed.
515109:05 PM10h50Karlsruhe, Hinterm Hauptbahnhof (Südeingang)7:55 AMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$731One-way0 transfers
Cheapest
515109:05 PM10h50Karlsruhe, Hinterm Hauptbahnhof (Südeingang)7:55 AMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$731One-way0 transfers
Fastest
9572+
61293:32 PM6h45Karlsruhe Hbf10:17 PMAvignon TGV$4651One-way1 transfer
Other options
4719+
5488 · 5124+
874229:07 AM14h07Karlsruhe Hbf11:14 PMAvignon TGV$3581One-way3 transfers
TGV 9574+
5488 · 512411:32 AM11h42Karlsruhe Hbf11:14 PMAvignon TGV$3701One-way2 transfers
TGV 9576+
5488 · 51249:53 AM13h21Karlsruhe Hbf11:14 PMAvignon TGV$3701One-way2 transfers
FlixBus8:20 PM10h55Karlsruhe Hbf7:15 AMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$811One-way0 transfers
FlixBus · FlixBus3:20 PM12h45Karlsruhe Hbf4:05 AMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$891One-way1 transfer
FlixBus · FlixBus4:05 AM13h00Karlsruhe Hbf5:05 PMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$891One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Karlsruhe to Avignon
Travel to Avignon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Avignon.

This is compared to other travel options from Karlsruhe to Avignon:
A bus is $105 (€86) less than a train for this route with tickets for a train from Karlsruhe to Avignon costing on average $164 (€134).
Other travel options to Avignon take longer:
Bus takes on average 10h 53m.
- Around 9 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Avignon as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Avignon TGV.
- Buses mostly depart from Karlsruhe Hbf and arrive in Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle).
- Travel with BlaBlaCar Bus, FlixBus to go to Avignon by bus.
- Travel with TGV, SNCF | TGV INOUI, Deutsche Bahn Intercity (DB IC) to go to Avignon by train.
- 2 direct buses per day with BlaBlaCar Bus, FlixBus.
- 1 direct trains per day with TGV, SNCF | TGV INOUI.
Travelling from Karlsruhe to Avignon: related information
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