Travel Information
Compare train and bus for Karlsruhe to Avignon
Omio recommends booking the train as it is the most popular option from Karlsruhe to Avignon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $88 For those with little time, consider booking a train, which has an average total journey time of 6h 39m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $88, while a train costs an average of $163.
Distance: 388 miles (625 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$163 Average price | $88 Average price Cheapest | $220 Average price (fuel + tolls) |
6h 39m Average total duration Fastest 6h 9m Onboard + 30m Additional time* | 11h 51m Average total duration 11h 21m Onboard + 30m Additional time* | 8h 11m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 0.6 - 1.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Avignon:
A bus is $76 (€64) less than a train for this route with tickets for a train from Karlsruhe to Avignon costing on average $163 (€137).
Other travel options to Avignon take longer:
Bus takes on average 11h 51m.
The journey is about 2h 2m faster (6h 9m by train vs 8h 11m by car) and roughly $56 (€47) cheaper once you factor in fuel and tolls ($163 (€137) vs $220 (€184)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Karlsruhe to Avignon
How to get from Karlsruhe to Avignon by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Avignon is by taking a bus because it’s the best combination of price and speed.
FlixBus8:20 PM10h55Karlsruhe Hbf7:15 AMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$631One-way0 transfers
Cheapest
FlixBus8:20 PM10h55Karlsruhe Hbf7:15 AMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$631One-way0 transfers
Fastest
EN89108:30 AM1h20Frankfurt am Main Airport9:50 AMLyon Saint Exupery Airport$6691One-way0 transfers
Other options
4721+
5537+
8742610:09 AM9h00Karlsruhe Hbf7:09 PMAvignon TGV$901One-way2 transfers
4719+
5537+
874229:07 AM10h02Karlsruhe Hbf7:09 PMAvignon TGV$901One-way2 transfers
ICE 9590+
553712:08 PM7h01Karlsruhe Hbf7:09 PMAvignon TGV$1011One-way1 transfer
FlixBus11:55 PM11h20Karlsruhe Hbf11:15 AMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$671One-way0 transfers
FlixBus · FlixBus12:55 AM15h15Karlsruhe Hbf4:10 PMLe Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)$1171One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Karlsruhe to Avignon
Travel to Avignon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Avignon.

This is compared to other travel options from Karlsruhe to Avignon:
A bus is $76 (€64) less than a train for this route with tickets for a train from Karlsruhe to Avignon costing on average $163 (€137).
Other travel options to Avignon take longer:
Bus takes on average 11h 51m.
- Around 19 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Avignon as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Avignon TGV.
- Buses mostly depart from Karlsruhe Hbf and arrive in Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle).
- Travel with SNCF | TGV INOUI, SNCF | Intercités de nuit, TGV to go to Avignon by train.
- Travel with BlaBlaCar Bus, FlixBus to go to Avignon by bus.
- 1 direct trains per day with SNCF | TGV INOUI.
- 3 direct buses per day with BlaBlaCar Bus, FlixBus.
Travelling from Karlsruhe to Avignon: related information
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