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Compare train and bus for Frankfurt am Main to Avignon
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Avignon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €78 For those with little time, consider booking a train, which has an average total journey time of 7h 40m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a bus costs an average of €78, while a train costs an average of €117.
Distance: 463 miles (746 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
€117 Average price | €78 Average price Cheapest | €207 Average price (fuel + tolls) |
7h 40m Average total duration Fastest 7h 10m Onboard + 30m Additional time* | 14h 51m Average total duration 14h 21m Onboard + 30m Additional time* | 9h 29m Average total duration (door-to-door) |
0.2 - 0.7kg CO2 emissions Lowest | 0.7 - 1.9kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Frankfurt am Main to Avignon
Compare the available ways to get from Frankfurt am Main to Avignon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Frankfurt am Main to Avignon:
A bus is €39 less than a train for this route with tickets for a train from Frankfurt am Main to Avignon costing on average €117.
Other travel options to Avignon take longer:
Bus takes on average 14h 51m.
The journey is about 2h 19m faster (7h 10m by train vs 9h 29m by car) and roughly €91 cheaper once you factor in fuel and tolls (€117 vs €207). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Frankfurt am Main to Avignon
How to get from Frankfurt am Main to Avignon by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Avignon is by taking a bus because it’s the best combination of price and speed.

7:05 PM 15h10 Frankfurt am Main 10:15 AM Avignon €49 1 One-way 0 transfers
Cheapest

7:05 PM 15h10 Frankfurt am Main 10:15 AM Avignon €49 1 One-way 0 transfers
Fastest

7:10 PM 15h05 Frankfurt am Main 10:15 AM Avignon €51 1 One-way 0 transfers
Other options

6:45 PM 15h30 Frankfurt am Main 10:15 AM Avignon €50 1 One-way 0 transfers
1:03 PM 21h12 Frankfurt am Main 10:15 AM Avignon €56 1 One-way 0 transfers
12:03 PM 21h12 Frankfurt am Main 9:15 AM Avignon €65 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Frankfurt am Main to Avignon
Travel to Avignon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Avignon.

This is compared to other travel options from Frankfurt am Main to Avignon:
A bus is €39 less than a train for this route with tickets for a train from Frankfurt am Main to Avignon costing on average €117.
Other travel options to Avignon take longer:
Bus takes on average 14h 51m.
- Around 15 trains per day.
- Around 9 buses per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Avignon as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Avignon TGV.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle).
- Travel with SNCF | TGV INOUI, TGV, SNCF | Intercités de nuit to go to Avignon by train.
- Travel with FlixBus, BlaBlaCar Bus, Sindbad to go to Avignon by bus.
- 1 direct trains per day with SNCF | TGV INOUI, TGV.
- 1 direct buses per day with BlaBlaCar Bus, Sindbad.
Travelling from Frankfurt am Main to Avignon: related information
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