Travel Information
Compare train, bus, and flight for Grenoble to Brussels
Omio recommends booking the train as it is the most popular option from Grenoble to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of zł210 For those with little time, consider booking a flight, which has an average total journey time of 3h 54m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of zł210, while a train costs an average of zł682.
Distance: 396 miles (638 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
zł682 Average price | zł210 Average price Cheapest | zł542 Average price | zł886 Average price (fuel + tolls) |
5h 32m Average total duration 5h 2m Onboard + 30m Additional time* | 11h 55m Average total duration 11h 25m Onboard + 30m Additional time* | 3h 54m Average total duration Fastest 1h 54m Onboard + 2h 0m Additional time* | 8h 3m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 0.6 - 1.6kg CO2 emissions | 1.9 - 3.8kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Grenoble to Brussels:
A bus is zł104 less than a train for this route with tickets for a train from Grenoble to Brussels costing on average zł359.
A bus is zł1271 less than a flight for this route with tickets for a flight from Grenoble to Brussels costing on average zł1526.
Other travel options to Brussels take longer:
Train takes on average 5h 26m.
Bus takes on average 12h 38m.
The journey is about 3h 7m faster (4h 56m by train vs 8h 3m by car) and roughly zł528 cheaper once you factor in fuel and tolls (zł359 vs zł886). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Grenoble to Brussels
How to get from Grenoble to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Grenoble to Brussels is by taking a bus because it’s the best combination of price and speed.
5132 · 165710:25 PM13h35Grenoble, Rue Emile Gueymard (Gare Routière)12:00 PMBrussels, Brussels South (Gare du Midi)zł1481One-way1 transfer
Cheapest
5132 · 165710:25 PM13h35Grenoble, Rue Emile Gueymard (Gare Routière)12:00 PMBrussels, Brussels South (Gare du Midi)zł1481One-way1 transfer
Fastest
SN27267:05 AM1h15Geneva International Airport8:20 AMBrussels Airportzł4811One-way0 transfers
Other options
17604+
6608+
93576:21 AM10h23Gare de Grenoble4:44 PMBrussels-Midizł5101One-way2 transfers
17604+
6608+
94716:21 AM12h56Gare de Grenoble7:17 PMBrussels-Midizł6731One-way2 transfers
17604+
6608+
94476:21 AM8h56Gare de Grenoble3:17 PMBrussels-Midizł7891One-way2 transfers
FlixBus · FlixBus7:00 PM13h15Grenoble, Rue Emile Gueymard (Gare Routière)8:15 AMBrussels, Brussels South (Gare du Midi)zł2111One-way1 transfer
51984 · 510957:15 PM12h45Grenoble, Rue Emile Gueymard (Gare Routière)8:00 AMBrussels, Brussels South (Gare du Midi)zł2371One-way1 transfer
FlixBus · FlixBus10:30 PM13h50Grenoble, Rue Emile Gueymard (Gare Routière)12:20 PMBrussels, Brussels South (Gare du Midi)zł2441One-way1 transfer
SN27128:15 AM1h20Geneva International Airport9:35 AMBrussels Airportzł4351One-way0 transfers
LX2809+
LX78011:00 AM3h15Geneva International Airport2:15 PMBrussels Airportzł5601One-way1 transfer
LX2807+
LX78010:00 AM4h15Geneva International Airport2:15 PMBrussels Airportzł5601One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Grenoble to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Grenoble to Brussels.

This is compared to other travel options from Grenoble to Brussels:
A bus is zł332 less than a flight for this route with tickets for a flight from Grenoble to Brussels costing on average zł542.
A bus is zł472 less than a train for this route with tickets for a train from Grenoble to Brussels costing on average zł682.
Other travel options to Brussels take longer:
Train takes on average 5h 32m.
Bus takes on average 11h 55m.
- Around 38 flights per day.
- Around 8 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Grenoble and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Geneva International Airport and arrive in Brussels Airport.
- Trains mostly depart from Gare de Grenoble and arrive in Brussels-Midi.
- Buses mostly depart from Grenoble, Rue Emile Gueymard (Gare Routière) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with FlixBus to go to Brussels by bus.
- Travel with SNCF | TGV INOUI to go to Brussels by train.
Travelling from Grenoble to Brussels: related information
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