Travel Information
Compare train, bus, and flight for Grenoble to Brussels
Omio recommends booking the train as it is the most popular option from Grenoble to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 2h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a train costs an average of $79.
Distance: 396 miles (638 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$178 Average price | $58 Average price Cheapest | $174 Average price |
5h 50m Average total duration 5h 20m Onboard + 30m Additional time* | 11h 57m Average total duration 11h 27m Onboard + 30m Additional time* | 5h 2m Average total duration Fastest 2h 2m Onboard + 3h 0m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 0.6 - 1.6kg CO2 emissions | 1.9 - 3.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Grenoble to Brussels
How to get from Grenoble to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Grenoble to Brussels is by taking a bus because it’s the best combination of price and speed.
5132 · 1657Cheapest
5132 · 1657Fastest
LX790Other options
17614+
9862
17626+
9868
17624+
5192 · 9894
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
SN2722
LX798
SN2724Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Grenoble to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Grenoble to Brussels.

This is compared to other travel options from Grenoble to Brussels:
A bus is $34 (€28) less than a flight for this route with tickets for a flight from Grenoble to Brussels costing on average $66 (€54).
A bus is $47 (€38) less than a train for this route with tickets for a train from Grenoble to Brussels costing on average $79 (€64).
Other travel options to Brussels take longer:
Train takes on average 5h 22m.
Bus takes on average 11h 35m.
- Around 37 flights per day.
- Around 9 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Grenoble and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Trains mostly depart from Gare de Grenoble and arrive in Brussels-Midi.
- Flights mostly depart from Geneva International Airport and arrive in Brussels Airport.
- Buses mostly depart from Grenoble, Rue Emile Gueymard (Gare Routière) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar to go to Brussels by bus.
- Travel with TGV, TGV INOUI to go to Brussels by train.
- Travel with Brussels Airlines, easyJet, SWISS, Vueling Airlines, Air Baltic to go to Brussels by flight.
- 0 direct buses per day with BlaBlaCar.
- 7 direct flights per day with Brussels Airlines, easyJet, SWISS, Air Baltic.
Travelling from Grenoble to Brussels: related information
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