Travel Information
Compare train, bus, and flight for Grenoble to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Grenoble to Frankfurt am Main among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $88 For those with little time, consider booking a flight, which has an average total journey time of 4h 49m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $88, while a flight costs an average of $542.
Distance: 367 miles (591 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$178 Average price | $88 Average price Cheapest | $542 Average price | $224 Average price (fuel + tolls) |
7h 45m Average total duration 7h 15m Onboard + 30m Additional time* | 13h 52m Average total duration 13h 22m Onboard + 30m Additional time* | 4h 49m Average total duration Fastest 2h 49m Onboard + 2h 0m Additional time* | 7h 26m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.5kg CO2 emissions | 1.8 - 3.5kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Grenoble to Frankfurt am Main:
A bus is $91 less than a train for this route with tickets for a train from Grenoble to Frankfurt am Main costing on average $178.
A bus is $454 less than a flight for this route with tickets for a flight from Grenoble to Frankfurt am Main costing on average $542.
Other travel options to Frankfurt am Main take longer:
Train takes on average 7h 45m.
Bus takes on average 13h 52m.
Tickets start at around $88 compared to roughly $224 in fuel and tolls — a saving of about $136. The journey takes 13h 22m versus 7h 26m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Grenoble to Frankfurt am Main
How to get from Grenoble to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Grenoble to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus11:30 PM13h20Grenoble, Rue Emile Gueymard (Gare Routière)12:50 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$611One-way1 transfer
Cheapest
FlixBus · FlixBus11:30 PM13h20Grenoble, Rue Emile Gueymard (Gare Routière)12:50 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$611One-way1 transfer
Fastest
LH12138:30 AM1h15Geneva International Airport9:45 AMFrankfurt am Main Airport$6341One-way0 transfers
Other options
6908+
95639:46 AM9h27Gare de Grenoble7:13 PMFrankfurt (Main) Hbf$3781One-way1 transfer
6910+
955512:47 PM8h16Gare de Grenoble9:03 PMFrankfurt (Main) Hbf$4121One-way1 transfer
17616+
6616+
956310:21 AM8h52Gare de Grenoble7:13 PMFrankfurt (Main) Hbf$4171One-way2 transfers
5132 · 5415210:25 PM14h55Grenoble, Rue Emile Gueymard (Gare Routière)1:20 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$621One-way1 transfer
FlixBus · FlixBus11:30 PM12h55Grenoble, Rue Emile Gueymard (Gare Routière)12:25 PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$661One-way1 transfer
FlixBus · FlixBus9:50 PM12h55Grenoble, Rue Emile Gueymard (Gare Routière)10:45 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$751One-way1 transfer
KL1426 · KL18176:30 AM4h35Lyon Saint Exupery Airport11:05 AMFrankfurt am Main Airport$2751One-way1 transfer
KL1426 · KL18196:30 AM7h05Lyon Saint Exupery Airport1:35 PMFrankfurt am Main Airport$2751One-way1 transfer
KL1426 · KL18256:30 AM15h30Lyon Saint Exupery Airport10:00 PMFrankfurt am Main Airport$2751One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Grenoble to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Grenoble to Frankfurt am Main.

This is compared to other travel options from Grenoble to Frankfurt am Main:
A bus is $91 less than a train for this route with tickets for a train from Grenoble to Frankfurt am Main costing on average $178.
A bus is $454 less than a flight for this route with tickets for a flight from Grenoble to Frankfurt am Main costing on average $542.
Other travel options to Frankfurt am Main take longer:
Train takes on average 7h 45m.
Bus takes on average 13h 52m.
- Around 60 flights per day.
- Around 11 buses per day.
- Around 7 trains per day.
However, we recommend checking specific travel dates for your route between Grenoble and Frankfurt am Main as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from Grenoble, Rue Emile Gueymard (Gare Routière) and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
- Trains mostly depart from Gare de Grenoble and arrive in Frankfurt (Main) Hbf.
- Flights mostly depart from Geneva International Airport and arrive in Frankfurt am Main Airport.
- Travel with BlaBlaCar Bus, FlixBus to go to Frankfurt am Main by bus.
- Travel with Société Nationale des Chemins de fer Français (SNCF) to go to Frankfurt am Main by train.
Travelling from Grenoble to Frankfurt am Main: related information
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