The cheapest and fastest trains from Grenoble to Brussels
Cheapest price
$147
Average price
$191
Fastest journey
5 h 35 m
Average duration
6 h 6 m
Trains per day
13
Distance
638 km
The best way to find a cheap train ticket from Grenoble to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Grenoble to Brussels will cost around $191 if you buy it on the day, but the cheapest tickets can be found for only $147.
It's difficult to get from Grenoble to Brussels without transferring at least once.
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Compare train, bus, and flight for Grenoble to Brussels
Omio recommends booking the train as it is the most popular option from Grenoble to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €22. For those with little time consider booking a flight which can get you there in 2h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €22, and a train costs an average of €94.
Distance: 396 miles (638 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€159 Average price | €51 Average price Cheapest | €155 Average price |
5h 50m Average total duration 5h 20m Onboard + 30m Additional time* | 12h 1m Average total duration 11h 31m Onboard + 30m Additional time* | 5h 2m Average total duration Fastest 2h 2m Onboard + 3h 0m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 0.6 - 1.6kg CO2 emissions | 1.9 - 3.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Grenoble to Brussels train times
The table below shows live departures for Grenoble to Brussels trains for today, Sunday, November 30. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:35 AM Grenoble | 6h08 | 3:43 PM Brussels | 0 transfersDirect | |
![]() | 12:40 PM Grenoble | 6h03 | 6:43 PM Brussels | 0 transfersDirect | |
![]() | 1:21 PM Grenoble | 5h22 | 6:43 PM Brussels | 0 transfersDirect | |
![]() | 3:21 PM Grenoble | 5h22 | 8:43 PM Brussels | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Grenoble to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Grenoble to Brussels trains with Omio?
TGV as well as TGV INOUI and SNCF offer trains services from Grenoble to Brussels. Omio is an official ticket reseller for all your travel options from Grenoble to Brussels.
Why book with Omio vs TGV?
- Compare with other providers: On Omio, you can not only buy tickets for TGV, but also compare tickets for the likes of TGV INOUI and SNCF to find the best option for your trip from Grenoble to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare TGV with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Grenoble to Brussels.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While TGV tickets can be bought on TGV's website or third party sellers, Omio allows you to compare with the likes of TGV INOUI and SNCF to help you choose the right option for your journey from Grenoble to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Grenoble to Brussels.
Journey information
Overview: Train from Grenoble to Brussels
Trains from Grenoble to Brussels run on average 3 times per day, taking around 5h 20m. Cheap train tickets for this journey start at $116 (€94) but you can travel from only $27 (€22) by bus.
The earliest train runs at 05:00, the last at 18:17. The fastest train covers the 396 miles (638 km) distance in 5h 22m.
Distance 396 miles (638 km) |
Average train duration 5h 20m |
Cheapest ticket price $116 (€94) |
Trains per day 3 |
Fastest train 5h 22m |
First train 05:00 |
Last train 18:17 |
Train companies: TGV, TGV INOUI, SNCF from Grenoble to Brussels trainsTGV, TGV INOUI, SNCF trains will get you between Grenoble and Brussels from $27 (€22). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
TGV INOUI
SNCF
FAQs: Trains from Grenoble to Brussels
Find answers to the most common questions about traveling from Grenoble to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Grenoble to Brussels
- 6:00 AM - 8:00 PM Monday - Sunday, closed on May 1st
- Free
- The car park is open 7 days a week with 214 spaces available. Access via Rue Emile Gueymard.
- Le Gratin Dauphinois
- Restaurant L'Inattendu
- Outside the main entrance.
- Ramps, restrooms.
- €0.50
- Hotel Europole
- Novotel Grenoble Centre
- Ibis Styles Grenoble Centre Gare
- Located in the main hall
- 50 places, covered
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-8 for trains to Lyon, Marseille, and international destinations
- Tramway: Line A, Line B
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 1:00 a.m. Departures can be made outside of opening hours. Access via Rue Pierre Sémard.
- Restaurant Le Gratin Dauphinois
- Le Petit Bouche
- Outside the main entrance.
- Ramps, restrooms.
- €0.50
- Residhotel Central Gare
- ibis Styles Grenoble Centre Gare
- Hotel Europole
- Located in the main hall
- 180 places, covered
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-6 for trains to Lyon, Marseille, and regional destinations
- Tramway: Line A, Line B
- Bus: Several lines available
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
Most popular train connections from Grenoble
More options for your journey from Grenoble to Brussels
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