- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
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Cheapest price
$224
Average price
$277
Fastest journey
5h 33m
Average duration
6h 50m
Trains per day
8
Distance
636 km
Omio recommends booking the train as it is the most popular option from Grenoble to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 2h 1m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $60.
Distance: 396 miles (638 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$186 Average price | $63 Average price Cheapest | $192 Average price | $230 Average price (fuel + tolls) |
5h 49m Average total duration 5h 19m Onboard + 30m Additional time* | 11h 57m Average total duration 11h 27m Onboard + 30m Additional time* | 5h 1m Average total duration Fastest 2h 1m Onboard + 3h 0m Additional time* | 8h 3m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 0.6 - 1.6kg CO2 emissions | 1.9 - 3.8kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Grenoble to Brussels:
A bus is $123 (€101) less than a train for this route with tickets for a train from Grenoble to Brussels costing on average $186 (€153).
A bus is $129 (€106) less than a flight for this route with tickets for a flight from Grenoble to Brussels costing on average $192 (€158).
Other travel options to Brussels take longer:
Train takes on average 5h 19m.
Bus takes on average 11h 27m.
The journey is about 2h 44m faster (5h 19m by train vs 8h 3m by car) and roughly $44 (€37) cheaper once you factor in fuel and tolls ($186 (€153) vs $230 (€190)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Grenoble to Brussels trains for today, Tuesday, July 14. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
6204+ 9477+ 17522 | Delayed 1:04 PM 1:30 PMGare de Grenoble | 6h47 | 8:17 PM Brussels-Midi | 2 transfers | |
6204+ 9393+ 17522 | Delayed 1:04 PM 1:30 PMGare de Grenoble | 9h17 | 10:47 PM Brussels-Midi | 2 transfers | |
6204+ 9377+ 17522 | Delayed 1:04 PM 1:30 PMGare de Grenoble | 6h47 | 8:17 PM Brussels-Midi | 2 transfers | |
408534+ 6626+ 9393 | On time 3:10 PM Grenoble Gare Routière | 7h37 | 10:47 PM Brussels-Midi | 2 transfers | |
408534+ 9868 | On time 3:10 PM Grenoble Gare Routière | 5h33 | 8:43 PM Brussels-Midi | 1 transfer | |
408546+ 6628+ 9393 | 4:10 PM Grenoble Gare Routière | 6h37 | 10:47 PM Brussels-Midi | 2 transfers | |
6352+ 9393 | 4:20 PM Gare de Grenoble | 6h27 | 10:47 PM Brussels-Midi | 1 transfer | |
408554+ 9882 | 5:10 PM Grenoble Gare Routière | 5h33 | 10:43 PM Brussels-Midi | 1 transfer | |
| Wednesday, July 15 | |||||
6906+ 9429 | 6:45 AM Gare de Grenoble | 5h32 | 12:17 PM Brussels-Midi | 1 transfer | |
6906+ 9341 | 6:45 AM Gare de Grenoble | 7h32 | 2:17 PM Brussels-Midi | 1 transfer | |
6906+ 9333 | 6:45 AM Gare de Grenoble | 6h02 | 12:47 PM Brussels-Midi | 1 transfer | |
6906+ 9435 | 6:45 AM Gare de Grenoble | 6h32 | 1:17 PM Brussels-Midi | 1 transfer | |
6906+ 9339 | 6:45 AM Gare de Grenoble | 6h59 | 1:44 PM Brussels-Midi | 1 transfer | |
6906+ 9329 | 6:45 AM Gare de Grenoble | 5h32 | 12:17 PM Brussels-Midi | 1 transfer | |
9854+ 17606 | 6:51 AM Gare de Grenoble | 5h20 | 12:11 PM Brussels-Midi | 1 transfer | |
17506+ 6250+ 9471 | 7:30 AM Gare de Grenoble | 11h47 | 7:17 PM Brussels-Midi | 2 transfers | |
17506+ 6250+ 9359 | 7:30 AM Gare de Grenoble | 9h48 | 5:18 PM Brussels-Midi | 2 transfers | |
17506+ 6250+ 9339 | 7:30 AM Gare de Grenoble | 6h14 | 1:44 PM Brussels-Midi | 2 transfers | |
17506+ 6250+ 9477 | 7:30 AM Gare de Grenoble | 12h47 | 8:17 PM Brussels-Midi | 2 transfers | |
6250+ 9341+ 17506 | 7:30 AM Gare de Grenoble | 6h47 | 2:17 PM Brussels-Midi | 2 transfers | |
17506+ 6250+ 9351 | 7:30 AM Gare de Grenoble | 8h14 | 3:44 PM Brussels-Midi | 2 transfers | |
6250+ 9377+ 17506 | 7:30 AM Gare de Grenoble | 12h47 | 8:17 PM Brussels-Midi | 2 transfers | |
6250+ 9451+ 17506 | 7:30 AM Gare de Grenoble | 8h14 | 3:44 PM Brussels-Midi | 2 transfers | |
17612+ 6612+ 9377 | 8:21 AM Gare de Grenoble | 11h56 | 8:17 PM Brussels-Midi | 2 transfers | |
17612+ 6612+ 9481 | 8:21 AM Gare de Grenoble | 12h26 | 8:47 PM Brussels-Midi | 2 transfers | |
17612+ 6612+ 9351 | 8:21 AM Gare de Grenoble | 7h23 | 3:44 PM Brussels-Midi | 2 transfers | |
6612+ 9477+ 17612 | 8:21 AM Gare de Grenoble | 11h56 | 8:17 PM Brussels-Midi | 2 transfers | |
6612+ 9451+ 17612 | 8:21 AM Gare de Grenoble | 7h23 | 3:44 PM Brussels-Midi | 2 transfers | |
6908+ 9377 | 9:46 AM Gare de Grenoble | 10h31 | 8:17 PM Brussels-Midi | 1 transfer | |
6908+ 9451 | 9:46 AM Gare de Grenoble | 5h58 | 3:44 PM Brussels-Midi | 1 transfer | |
6908+ 9481 | 9:46 AM Gare de Grenoble | 11h01 | 8:47 PM Brussels-Midi | 1 transfer | |
6908+ 9387 | 9:46 AM Gare de Grenoble | 11h58 | 9:44 PM Brussels-Midi | 1 transfer | |
6908+ 9351 | 9:46 AM Gare de Grenoble | 5h58 | 3:44 PM Brussels-Midi | 1 transfer | |
17618+ 6618+ 9481 | 11:21 AM Gare de Grenoble | 9h26 | 8:47 PM Brussels-Midi | 2 transfers | |
17618+ 6618+ 9387 | 11:21 AM Gare de Grenoble | 10h23 | 9:44 PM Brussels-Midi | 2 transfers | |
17618+ 6618+ 9393 | 11:21 AM Gare de Grenoble | 11h26 | 10:47 PM Brussels-Midi | 2 transfers | |
17620+ 6620+ 9481 | 12:21 PM Gare de Grenoble | 8h26 | 8:47 PM Brussels-Midi | 2 transfers | |
17620+ 6620+ 9387 | 12:21 PM Gare de Grenoble | 9h23 | 9:44 PM Brussels-Midi | 2 transfers | |
17620+ 6620+ 9393 | 12:21 PM Gare de Grenoble | 10h26 | 10:47 PM Brussels-Midi | 2 transfers | |
17520+ 9708+ 9387 | 12:30 PM Gare de Grenoble | 9h14 | 9:44 PM Brussels-Midi | 2 transfers | |
17520+ 9708+ 9393 | 12:30 PM Gare de Grenoble | 10h17 | 10:47 PM Brussels-Midi | 2 transfers | |
9708+ 9481+ 17520 | 12:30 PM Gare de Grenoble | 8h17 | 8:47 PM Brussels-Midi | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Grenoble to Brussels run on average 3 times per day, taking around 5h 19m. Cheap train tickets for this journey start at $87 (€72) but you can travel from only $34 (€28) by bus.
The earliest train runs at 06:03, the last at 18:17. The fastest train covers the 396 miles (638 km) distance in 5h 30m.
Distance 396 miles (638 km) |
Average train duration 5h 19m |
Cheapest ticket price $87 (€72) |
Trains per day 3 |
Fastest train 5h 30m |
First train 6:03 AM |
Last train 6:17 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Mon |
Best time to book 4 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels-Midi -> Brussels-Central
Find answers to the most common questions about traveling from Grenoble to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Grenoble to Brussels trains use the Gare de Grenoble to Bruxelles-Midi station pair. Use this guide to compare Grenoble and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Gare de Grenoble has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Le Gratin Dauphinois, Le Petit Bouche
Free. ATMs are available in the train station.
Ticket office support is available at Gare de Grenoble. Information desks are located in the main hall.
Luggage storage is available at Gare de Grenoble. Lost and found is available at the station.
Available at Gare de Grenoble: Parking, Taxis, WC.
Available at Gare de Grenoble: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Gare de Grenoble: Ramps, restrooms.
Nearby hotels include Residhotel Central Gare, ibis Styles Grenoble Centre Gare, Hotel Europole.
Grenoble, Gare Routière has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Le Gratin Dauphinois, Restaurant L'Inattendu
Free.
Ticket office support is available at Grenoble, Gare Routière. Information desks are located in the main hall.
Luggage storage is available at Grenoble, Gare Routière. Lost and found is available at the station.
Available at Grenoble, Gare Routière: Parking, Taxis, WC.
Available at Grenoble, Gare Routière: Bike Parking, Car Rental.
Accessibility facilities are available at Grenoble, Gare Routière: Ramps, restrooms.
Nearby hotels include Hotel Europole, Novotel Grenoble Centre, Ibis Styles Grenoble Centre Gare.
Bruxelles-Midi has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Pullman Hotel Bar, Quick Gare du Midi, Subway, EXKi Zuid, Starbucks, Häagen-Dazs, Sbarro, The Coffee Club, The Belgian Chocolate House, PAUL, & many more
Wi-Fi is available for a fee. ATMs are available at Bruxelles-Midi.
Ticket office support is available at Bruxelles-Midi. Information desks are located in the main concourse and next to the international platforms.
Luggage storage is baggage storage facility is located across from the Thalys business lounge.
Available at Bruxelles-Midi: Parking, Taxis, WC.
Available at Bruxelles-Midi: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Bruxelles-Midi: Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Nearby hotels include Les Lofts De Styliste, Park Inn by Radisson Brussels Midi, Pullman Brussels Centre Midi.
Here are some other resources that might have the information you need