The cheapest and fastest trains from Wuppertal to Prague
Cheapest price
$122
Average price
$153
Fastest journey
8 h 51 m
Average duration
8 h 58 m
Trains per day
8
Distance
528 km
The best way to find a cheap train ticket from Wuppertal to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Wuppertal to Prague will cost around $153 if you buy it on the day, but the cheapest tickets can be found for only $122.
It's difficult to get from Wuppertal to Prague without transferring at least 2 times.
S 30929 · ICE 547 · rj 17710:23 AM8h52Wuppertal Hbf7:15 PMPrague-Holešovice$1221One-way2 transfers
RE 26411 · ICE 1547 · rj 17710:07 AM9h08Wuppertal Hbf7:15 PMPrague-Holešovice$1221One-way2 transfers
S8 · ICE 625 · 3573+
36110:38 AM9h43Wuppertal Hbf8:21 PMPrague hlavní nádraží$1311One-way3 transfers
S 30921 · ICE 545 · rj 3838:23 AM9h02Wuppertal Hbf5:25 PMPrague hlavní nádraží$1541One-way2 transfers
S9 · ICE 545 · RJ 3838:23 AM9h02Wuppertal Hbf5:25 PMPrague hlavní nádraží$1591One-way2 transfers
S9 · ICE 547 · RJ 17710:23 AM8h51Wuppertal Hbf7:14 PMPrague-Holešovice$1881One-way2 transfers
S 30929 · ICE 547 · rj 17710:23 AM8h52Wuppertal Hbf7:15 PMPrague-Holešovice$1221One-way2 transfers
S 30921 · ICE 545 · rj 3838:23 AM9h02Wuppertal Hbf5:25 PMPrague hlavní nádraží$1541One-way2 transfers
S9 · ICE 545 · RJ 3838:23 AM9h02Wuppertal Hbf5:25 PMPrague hlavní nádraží$1591One-way2 transfers
S9 · ICE 549 · ECE 38512:23 PM9h02Wuppertal Hbf9:25 PMPrague hlavní nádraží$1881One-way2 transfers
Travel Information
Compare train, bus, and flight for Wuppertal to Prague
Omio recommends booking the train as it is the most popular option from Wuppertal to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a flight which can get you there in 1h 17m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $37, and a flight costs an average of $55.
Distance: 328 miles (528 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$89 Average price | $163 Average price | $59 Average price Cheapest |
9h 25m Average total duration 8h 55m Onboard + 30m Additional time* | 4h 17m Average total duration Fastest 1h 17m Onboard + 3h 0m Additional time* | 10h 4m Average total duration 9h 34m Onboard + 30m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.2kg CO2 emissions | 0.5 - 1.3kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Wuppertal to Prague train times
The table below shows live departures for Wuppertal to Prague trains for today, Tuesday, May 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
S9 · ICE 549 · ECE 385 | 12:23 PM Wuppertal Hbf | 9h02 | 9:25 PM Prague hlavní nádraží | 2 transfers | |
| Wednesday, May 6 | |||||
S9 · ICE 545 · RJ 383 | 8:23 AM Wuppertal Hbf | 9h02 | 5:25 PM Prague hlavní nádraží | 2 transfers | |
S 30921 · ICE 545 · rj 383 | On time 8:23 AM Wuppertal Hbf | 9h02 | 5:25 PM Prague hlavní nádraží | 2 transfers | |
S8 · ICE 621 · 3569+ 359 | 8:38 AM Wuppertal Hbf | 9h43 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
RE 26411 · ICE 1547 · rj 177 | 10:07 AM Wuppertal Hbf | 9h08 | 7:15 PM Prague-Holešovice | 2 transfers | |
S9 · ICE 547 · RJ 177 | 10:23 AM Wuppertal Hbf | 8h51 | 7:14 PM Prague-Holešovice | 2 transfers | |
S 30929 · ICE 547 · rj 177 | On time 10:23 AM Wuppertal Hbf | 8h52 | 7:15 PM Prague-Holešovice | 2 transfers | |
S8 · ICE 625 · 3573+ 361 | 10:38 AM Wuppertal Hbf | 9h43 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Wuppertal to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 06
May 07
May 08
May 09
May 10
May 11
May 12
Why should you book Wuppertal to Prague trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH to find the best option for your trip from Wuppertal to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Wuppertal to Prague.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH to find the best option for your trip from Wuppertal to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Wuppertal to Prague.
Journey information
Overview: Train from Wuppertal to Prague
Trains from Wuppertal to Prague run on average 10 times per day, taking around 8h 55m. Cheap train tickets for this journey start at $39 (€31) but you can travel from only $37 (€30) by bus.
The earliest train runs at 00:23, the last at 23:58. The fastest train covers the 328 miles (528 km) distance in 8h 0m.
Distance 328 miles (528 km) |
Average train duration 8h 55m |
Cheapest ticket price $39 (€31) |
Trains per day 10 |
Fastest train 8h 0m |
First train 12:23 AM |
Last train 11:58 PM |
Cheapest Month Apr |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Fri |
Train companies: Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH from Wuppertal to Prague trainsDeutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH trains will get you between Wuppertal and Prague from $37 (€30). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
alex-Länderbahn und Vogtlandbahn-GmbH
České dráhy
FAQs: Trains from Wuppertal to Prague
Find answers to the most common questions about traveling from Wuppertal to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Wuppertal to Prague
- Monday: 08:00 - 18:00
- Tuesday: 08:00 - 18:00
- Wednesday: 08:00 - 18:00
- Thursday: 08:00 - 18:00
- Friday: 08:00 - 18:00
- Saturday: 09:00 - 14:00
- Vidaleo
- Cafe Extrablatt
- McDonald's
- KYTO Coffee Wuppertal
- Central-Hotel
- Ibis Wuppertal City
- Hotel Astor
- Arcade
- Vidaleo
- KYTO Coffee Wuppertal
- Laurenz
- Milia´s Coffee
- Central-Hotel
- Hotel Astor
- Hotel Hanseatic
- Arcade
- Yom Döner
- Hardt-Stübchen
- Subway
- Cafeteria im Amtsgericht
- Also-Hotel an der Hardt
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
Most popular train connections from Wuppertal
More options for your journey from Wuppertal to Prague
Here are some other resources that might have the information you need


