Siena to Milan Centrale train with Italo

Fri, Feb 06
+ Add return
Italo
Frecciarossa
Regionale
Intercity
Deutsche Bahn
1,000+ travel companies
Italo
Frecciarossa
Regionale
Intercity
Deutsche Bahn
1,000+ travel companies
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The cheapest and fastest trains from Siena to Milan Centrale

Showing times and prices for Feb 06

Cheapest price

$46

Average price

$83

Fastest journey

3 h 25 m

Average duration

3 h 53 m

Trains per day

127

Distance

294 km

Cheap tickets

The best way to find a cheap train ticket from Siena to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Siena to Milan Centrale will cost around $83 if you buy it on the day, but the cheapest tickets can be found for only $46.

Fast trains

It's difficult to get from Siena to Milan Centrale without transferring at least once.

RegionaleRegionale 19044 · ETRUSCHI LINE 18307 · Regionale 2296
04:41PM6h41
Siena station
11:22PMMilan Centrale
$461One-way
2 transfers
RegionaleRegionale 18208 · Regionale 17816 · Regionale Veloce TTPER 2470
06:36AM8h09
Siena station
02:45PMMilan Centrale
$481One-way
2 transfers
RegionaleRegionale 18234+IntercityIntercity 596
05:18PM5h59
Siena station
11:17PMMilan Centrale
$541One-way
1 transfer
RegionaleRegionale 19046 · Tuscany Line 4052+IntercityIntercity 596
05:41PM5h36
Siena station
11:17PMMilan Centrale
$541One-way
2 transfers
RegionaleRegionale 18228 · Regionale 18381+IntercityIntercity 684
03:18PM6h37
Siena station
09:55PMMilan Centrale
$591One-way
2 transfers

Travel Information

Compare bus, train, and flight for Siena to Milan Centrale

Omio recommends booking the train as it is the most popular option from Siena to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a train which can get you there in 4h 4m. The ticket price range depends on the travel mode: a bus costs an average of €8, and a flight costs an average of €103.

Distance: 182 miles (294 km)

Compare train with

Most popular
Train
Bus
Flight

€37

Average price

€16

Average price

Cheapest

€171

Average price

4h 34m

Average total duration

Fastest

4h 4m

Onboard

+

30m

Additional time*

5h 28m

Average total duration

4h 58m

Onboard

+

30m

Additional time*

12h 41m

Average total duration

9h 41m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Siena to Milan Centrale train times

The table below shows live departures for Siena to Milan Centrale trains for today, Thursday, February 5. You can also manually refresh the results below to see updated train journeys.

Last updated at 11:35 AM
ProviderDepartsDurationArrivesTransfers
Tickets
trenitaliareg2:41 PM Siena
6h41
9:22 PM Milan Centrale0 transfersDirect
Friday, February 6
trenitaliaregRegionale 19030 · Regionale 18254+italo99124:00 AM Siena station
6h20
10:20 AM Milan Centrale2 transfers
trenitaliaregRegionale 19030 · Regionale 18254+italo9904
On time
4:00 AM Siena station
4h20
8:20 AM Milan Centrale
2 transfers
trenitaliaregRegionale 19030 · Regionale 18254+italo99084:00 AM Siena station
5h20
9:20 AM Milan Centrale2 transfers
trenitaliaregRegionale 18200+italo99164:43 AM Siena station
6h37
11:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18200+italo99124:43 AM Siena station
5h37
10:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18200+italo99084:43 AM Siena station
4h37
9:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18204+italo99125:13 AM Siena station
5h07
10:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18204+italo99165:13 AM Siena station
6h07
11:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18204+italo99085:13 AM Siena station
4h07
9:20 AM Milan Centrale1 transfer
trenitaliaregRegionale Veloce 4010+italo99085:25 AM Siena station
3h55
9:20 AM Milan Centrale1 transfer
trenitaliaregRegionale Veloce 4010+frecciarossaFRECCIAROSSA 1000 95085:25 AM Siena station
3h25
8:50 AM Milan Centrale1 transfer
trenitaliaregRegionale Veloce 4010+trenitaliaintIntercity 5805:25 AM Siena station
5h50
11:15 AM Milan Centrale1 transfer
trenitaliaregRegionale Veloce 4010+italo99125:25 AM Siena station
4h55
10:20 AM Milan Centrale1 transfer
trenitaliaregRegionale Veloce 4010+italo99165:25 AM Siena station
5h55
11:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18208+frecciarossaFRECCIAROSSA 95125:36 AM Siena station
4h14
9:50 AM Milan Centrale1 transfer
trenitaliaregRegionale 18208 · Regionale 17816+trenitaliaintIntercity 6045:36 AM Siena station
7h04
12:40 PM Milan Centrale2 transfers
trenitaliaregRegionale 18208+italo99125:36 AM Siena station
4h44
10:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18208+italo99205:36 AM Siena station
6h44
12:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18208+italo99165:36 AM Siena station
5h44
11:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18208 · Regionale 17816 · Regionale Veloce TTPER 24705:36 AM Siena station
8h09
1:45 PM Milan Centrale2 transfers
trenitaliaregRegionale 18212+frecciarossaFRECCIAROSSA 1000 9406 · FRECCIAROSSA 1000 96166:02 AM Siena station
4h33
10:35 AM Milan Centrale2 transfers
trenitaliaregRegionale 18212+italo99166:02 AM Siena station
5h18
11:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18212+frecciarossaFRECCIAROSSA 95166:02 AM Siena station
4h48
10:50 AM Milan Centrale1 transfer
trenitaliaregRegionale 18212+italo99126:02 AM Siena station
4h18
10:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18212+italo99206:02 AM Siena station
6h18
12:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 19114 · ETRUSCHI LINE 4016+italo99246:33 AM Siena station
6h47
1:20 PM Milan Centrale2 transfers
trenitaliaregRegionale 19114 · ETRUSCHI LINE 4016+italo99166:33 AM Siena station
4h47
11:20 AM Milan Centrale2 transfers
trenitaliaregRegionale 19114 · ETRUSCHI LINE 4016+italo99206:33 AM Siena station
5h47
12:20 PM Milan Centrale2 transfers
trenitaliaregRegionale 19114 · ETRUSCHI LINE 4016+frecciarossaFRECCIAROSSA 95166:33 AM Siena station
4h17
10:50 AM Milan Centrale2 transfers
trenitaliaregRegionale 18214+italo99167:18 AM Siena station
4h02
11:20 AM Milan Centrale1 transfer
trenitaliaregRegionale 18214+frecciarossaFRECCIAROSSA 9490 · FRECCIAROSSA 88107:18 AM Siena station
4h12
11:30 AM Milan Centrale2 transfers
trenitaliaregRegionale 18214+italo99207:18 AM Siena station
5h02
12:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18214+italo99247:18 AM Siena station
6h02
1:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18278+italo99207:48 AM Siena station
4h32
12:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18278+italo99247:48 AM Siena station
5h32
1:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18278+italo99287:48 AM Siena station
6h32
2:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18278+frecciarossaFRECCIAROSSA 95207:48 AM Siena station
4h02
11:50 AM Milan Centrale1 transfer
trenitaliaregRegionale 18218+italo99288:18 AM Siena station
6h02
2:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18218+frecciarossaFRECCIAROSSA 95248:18 AM Siena station
4h32
12:50 PM Milan Centrale1 transfer
trenitaliaregRegionale 18218 · Regionale 18361+trenitaliaintIntercity 6708:18 AM Siena station
6h37
2:55 PM Milan Centrale2 transfers
trenitaliaregRegionale 18218+italo99208:18 AM Siena station
4h02
12:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18218+italo99248:18 AM Siena station
5h02
1:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 19032 · TUSCANY LINE 4030+italo99329:41 AM Siena station
5h39
3:20 PM Milan Centrale2 transfers
trenitaliaregRegionale 19032 · TUSCANY LINE 4030+frecciarossaFRECCIAROSSA 1000 95149:41 AM Siena station
4h09
1:50 PM Milan Centrale2 transfers
trenitaliaregRegionale 19032 · TUSCANY LINE 4030+italo81349:41 AM Siena station
6h39
4:20 PM Milan Centrale2 transfers
trenitaliaregRegionale 19032 · TUSCANY LINE 4030+italo99289:41 AM Siena station
4h39
2:20 PM Milan Centrale2 transfers
trenitaliaregRegionale 18220+italo993210:18 AM Siena station
5h02
3:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18220+italo813410:18 AM Siena station
6h02
4:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18220+trenitaliaintIntercity 588 · Intercity 60810:18 AM Siena station
6h27
4:45 PM Milan Centrale2 transfers
trenitaliaregRegionale 18220+italo992810:18 AM Siena station
4h02
2:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18220+frecciarossaFRECCIAROSSA 953210:18 AM Siena station
4h32
2:50 PM Milan Centrale1 transfer
trenitaliaregRegionale 18220+frecciarossaFRECCIAROSSA 1000 8418 · FRECCIAROSSA 1000 963210:18 AM Siena station
4h17
2:35 PM Milan Centrale2 transfers
trenitaliaregRegionale 19034 · TUSCANY LINE 4032+italo813410:45 AM Siena station
5h35
4:20 PM Milan Centrale2 transfers
trenitaliaregRegionale 19034 · TUSCANY LINE 4032+italo994010:45 AM Siena station
6h35
5:20 PM Milan Centrale2 transfers
trenitaliaregRegionale 19034 · TUSCANY LINE 4032+italo993210:45 AM Siena station
4h35
3:20 PM Milan Centrale2 transfers
trenitaliaregRegionale 19034 · TUSCANY LINE 4032+frecciarossaFRECCIAROSSA 953210:45 AM Siena station
4h05
2:50 PM Milan Centrale2 transfers
trenitaliaregRegionale 18222+frecciarossaFRECCIAROSSA 958411:18 AM Siena station
4h32
3:50 PM Milan Centrale1 transfer
trenitaliaregRegionale 18222+italo993211:18 AM Siena station
4h02
3:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18222+italo994011:18 AM Siena station
6h02
5:20 PM Milan Centrale1 transfer
trenitaliaregRegionale 18222+italo813411:18 AM Siena station
5h02
4:20 PM Milan Centrale1 transfer

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Siena to Milan Centrale by bus, train, or flight

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Why should you book Siena to Milan Centrale trains with Omio?

Italo as well as Frecciarossa, Regionale, Intercity and more offer trains services from Siena to Milan Centrale.
Omio is the only official third party seller for Italo tickets.

Why book with Omio vs Italo?

  • Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale or Intercity to find the best option for your trip from Siena to Milan Centrale.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Siena to Milan Centrale.

Why book with Omio over Raileurope?

  • Official reseller: Italo tickets can only be bought on Omio or Italo's website as Omio is the only official third party seller for Italo tickets. Raileurope do not sell Italo tickets as they are not official sellers.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Siena to Milan Centrale.

Journey information

Overview: Train from Siena to Milan Centrale

ItalyItaly
ItalyItaly
Icon of train

Trains from Siena to Milan Centrale run on average 29 times per day, taking around 4h 4m. Cheap train tickets for this journey start at $29 (€23) but you can travel from only $10 (€8) by bus.

The earliest train runs at 03:40, the last at 18:23. The fastest train covers the 182 miles (294 km) distance in 5h 36m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $10 (€8)
Distance
182 miles (294 km)
Average train duration
4h 4m
Cheapest ticket price
$29 (€23)
Trains per day
29
Fastest train
5h 36m
First train
03:40
Last train
18:23
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $10 (€8)

Train companies: Italo, Frecciarossa, Regionale, Intercity from Siena to Milan Centrale trainsItalo, Frecciarossa, Regionale, Intercity trains will get you between Siena and Milan Centrale from $10 (€8). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Italo

About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Italo frequency
8 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone

Frecciarossa

About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
7h 2m
Cheapest Price
$54 (€43)
Frecciarossa frequency
16 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone

Regionale

About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
6h 41m
Cheapest Price
$40 (€32)
Regionale frequency
6 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone

Intercity

About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
5h 36m
Cheapest Price
$25 (€20)
Intercity frequency
7 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone

FAQs: Trains from Siena to Milan Centrale

Find answers to the most common questions about traveling from Siena to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Siena to Milan Centrale can vary. The cheapest ticket starts at $29 (€23), while the average price is around $46 (€37).
The train from Siena to Milan Centrale takes 5h 36m and runs 29 per day.
The distance by train from Siena to Milan Centrale is 182 miles (294 km).
The first train from Siena to Milan Centrale leaves at 3:40 AM.
The last train from Siena to Milan Centrale leaves at 6:23 PM.
Yes, there is a high-speed train from Siena to Milan Centrale.
Yes, there is a direct train from Siena to Milan Centrale. This service operates 0 times per day, provided by Italo.
Unfortunately, there is no night train available from Siena to Milan Centrale.
The cheapest way to get from Siena to Milan Centrale is by bus, with a cost of around $10 (€8).
The train journey from Siena to Milano Centrale is moderately scenic, offering views of Tuscany's rolling hills, charming villages, and vineyards, especially in the initial part of the journey. As the train approaches Milan, the scenery becomes more urban and industrial.
A day trip from Siena to Milano Centrale is not feasible as the journey takes 5h 36m one way. However, there are 29 train trips per day covering the 182 miles (294 km) distance.
Yes, you can take the train from Siena to Milan Centrale.

popular train stations

Popular train stations from Siena to Milan Centrale

Siena
Milan
The major train station for departures in Siena is Siena. Find all the information you need to know about services, amenities and connections at Siena for your trip from Siena to Milan.
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 6:00 AM - 8:00 PM Monday - Sunday
ticketOfficeHours
Distance to city center
1 km
platformCount
Number of platforms
5
Wifi
Wifi
  • Free
Parking
Parking
  • Parking is available near the station, open 24/7.
Dining
Dining
  • Ristorante Il Vinaio
  • Osteria Le Logge
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps.
WC
WC
  • €1
Hotel
Hotel
  • Hotel Italia
  • NH Siena
  • Hotel Minerva
Lost and Found Office
Lost and Found Office
  • Located near the main entrance
Information Desk
Information Desk
  • Located near the main entrance
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • The station has a single-level layout with platforms accessible from the main hall.
Public transit options for Siena
  • Bus: Several local and regional lines available
  • Taxi: Available outside the station

More options for your journey from Siena to Milan Centrale

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