The cheapest and fastest trains from Siena to Milan Centrale
Cheapest price
$46
Average price
$83
Fastest journey
3 h 25 m
Average duration
3 h 53 m
Trains per day
127
Distance
294 km
The best way to find a cheap train ticket from Siena to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Milan Centrale will cost around $83 if you buy it on the day, but the cheapest tickets can be found for only $46.
It's difficult to get from Siena to Milan Centrale without transferring at least once.
Regionale 19044 · ETRUSCHI LINE 18307 · Regionale 2296
Regionale 18208 · Regionale 17816 · Regionale Veloce TTPER 2470
Regionale 18234+
Intercity 596
Regionale 19046 · Tuscany Line 4052+
Intercity 596
Regionale 18228 · Regionale 18381+
Intercity 684
Regionale Veloce 4010+
FRECCIAROSSA 1000 9508
Regionale Veloce 4010+
9908
Regionale 18242+
9962
Regionale 18238+
8158
Regionale 18236+
9954Travel Information
Compare bus, train, and flight for Siena to Milan Centrale
Omio recommends booking the train as it is the most popular option from Siena to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a train which can get you there in 4h 4m. The ticket price range depends on the travel mode: a bus costs an average of €8, and a flight costs an average of €103.
Distance: 182 miles (294 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€37 Average price | €16 Average price Cheapest | €171 Average price |
4h 34m Average total duration Fastest 4h 4m Onboard + 30m Additional time* | 5h 28m Average total duration 4h 58m Onboard + 30m Additional time* | 12h 41m Average total duration 9h 41m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Siena to Milan Centrale train times
The table below shows live departures for Siena to Milan Centrale trains for today, Thursday, February 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:41 PM Siena | 6h41 | 9:22 PM Milan Centrale | 0 transfersDirect | |
| Friday, February 6 | |||||
Regionale 19030 · Regionale 18254+ 9912 | 4:00 AM Siena station | 6h20 | 10:20 AM Milan Centrale | 2 transfers | |
Regionale 19030 · Regionale 18254+ 9904 | On time 4:00 AM Siena station | 4h20 | 8:20 AM Milan Centrale | 2 transfers | |
Regionale 19030 · Regionale 18254+ 9908 | 4:00 AM Siena station | 5h20 | 9:20 AM Milan Centrale | 2 transfers | |
Regionale 18200+ 9916 | 4:43 AM Siena station | 6h37 | 11:20 AM Milan Centrale | 1 transfer | |
Regionale 18200+ 9912 | 4:43 AM Siena station | 5h37 | 10:20 AM Milan Centrale | 1 transfer | |
Regionale 18200+ 9908 | 4:43 AM Siena station | 4h37 | 9:20 AM Milan Centrale | 1 transfer | |
Regionale 18204+ 9912 | 5:13 AM Siena station | 5h07 | 10:20 AM Milan Centrale | 1 transfer | |
Regionale 18204+ 9916 | 5:13 AM Siena station | 6h07 | 11:20 AM Milan Centrale | 1 transfer | |
Regionale 18204+ 9908 | 5:13 AM Siena station | 4h07 | 9:20 AM Milan Centrale | 1 transfer | |
Regionale Veloce 4010+ 9908 | 5:25 AM Siena station | 3h55 | 9:20 AM Milan Centrale | 1 transfer | |
Regionale Veloce 4010+ FRECCIAROSSA 1000 9508 | 5:25 AM Siena station | 3h25 | 8:50 AM Milan Centrale | 1 transfer | |
Regionale Veloce 4010+ Intercity 580 | 5:25 AM Siena station | 5h50 | 11:15 AM Milan Centrale | 1 transfer | |
Regionale Veloce 4010+ 9912 | 5:25 AM Siena station | 4h55 | 10:20 AM Milan Centrale | 1 transfer | |
Regionale Veloce 4010+ 9916 | 5:25 AM Siena station | 5h55 | 11:20 AM Milan Centrale | 1 transfer | |
Regionale 18208+ FRECCIAROSSA 9512 | 5:36 AM Siena station | 4h14 | 9:50 AM Milan Centrale | 1 transfer | |
Regionale 18208 · Regionale 17816+ Intercity 604 | 5:36 AM Siena station | 7h04 | 12:40 PM Milan Centrale | 2 transfers | |
Regionale 18208+ 9912 | 5:36 AM Siena station | 4h44 | 10:20 AM Milan Centrale | 1 transfer | |
Regionale 18208+ 9920 | 5:36 AM Siena station | 6h44 | 12:20 PM Milan Centrale | 1 transfer | |
Regionale 18208+ 9916 | 5:36 AM Siena station | 5h44 | 11:20 AM Milan Centrale | 1 transfer | |
Regionale 18208 · Regionale 17816 · Regionale Veloce TTPER 2470 | 5:36 AM Siena station | 8h09 | 1:45 PM Milan Centrale | 2 transfers | |
Regionale 18212+ FRECCIAROSSA 1000 9406 · FRECCIAROSSA 1000 9616 | 6:02 AM Siena station | 4h33 | 10:35 AM Milan Centrale | 2 transfers | |
Regionale 18212+ 9916 | 6:02 AM Siena station | 5h18 | 11:20 AM Milan Centrale | 1 transfer | |
Regionale 18212+ FRECCIAROSSA 9516 | 6:02 AM Siena station | 4h48 | 10:50 AM Milan Centrale | 1 transfer | |
Regionale 18212+ 9912 | 6:02 AM Siena station | 4h18 | 10:20 AM Milan Centrale | 1 transfer | |
Regionale 18212+ 9920 | 6:02 AM Siena station | 6h18 | 12:20 PM Milan Centrale | 1 transfer | |
Regionale 19114 · ETRUSCHI LINE 4016+ 9924 | 6:33 AM Siena station | 6h47 | 1:20 PM Milan Centrale | 2 transfers | |
Regionale 19114 · ETRUSCHI LINE 4016+ 9916 | 6:33 AM Siena station | 4h47 | 11:20 AM Milan Centrale | 2 transfers | |
Regionale 19114 · ETRUSCHI LINE 4016+ 9920 | 6:33 AM Siena station | 5h47 | 12:20 PM Milan Centrale | 2 transfers | |
Regionale 19114 · ETRUSCHI LINE 4016+ FRECCIAROSSA 9516 | 6:33 AM Siena station | 4h17 | 10:50 AM Milan Centrale | 2 transfers | |
Regionale 18214+ 9916 | 7:18 AM Siena station | 4h02 | 11:20 AM Milan Centrale | 1 transfer | |
Regionale 18214+ FRECCIAROSSA 9490 · FRECCIAROSSA 8810 | 7:18 AM Siena station | 4h12 | 11:30 AM Milan Centrale | 2 transfers | |
Regionale 18214+ 9920 | 7:18 AM Siena station | 5h02 | 12:20 PM Milan Centrale | 1 transfer | |
Regionale 18214+ 9924 | 7:18 AM Siena station | 6h02 | 1:20 PM Milan Centrale | 1 transfer | |
Regionale 18278+ 9920 | 7:48 AM Siena station | 4h32 | 12:20 PM Milan Centrale | 1 transfer | |
Regionale 18278+ 9924 | 7:48 AM Siena station | 5h32 | 1:20 PM Milan Centrale | 1 transfer | |
Regionale 18278+ 9928 | 7:48 AM Siena station | 6h32 | 2:20 PM Milan Centrale | 1 transfer | |
Regionale 18278+ FRECCIAROSSA 9520 | 7:48 AM Siena station | 4h02 | 11:50 AM Milan Centrale | 1 transfer | |
Regionale 18218+ 9928 | 8:18 AM Siena station | 6h02 | 2:20 PM Milan Centrale | 1 transfer | |
Regionale 18218+ FRECCIAROSSA 9524 | 8:18 AM Siena station | 4h32 | 12:50 PM Milan Centrale | 1 transfer | |
Regionale 18218 · Regionale 18361+ Intercity 670 | 8:18 AM Siena station | 6h37 | 2:55 PM Milan Centrale | 2 transfers | |
Regionale 18218+ 9920 | 8:18 AM Siena station | 4h02 | 12:20 PM Milan Centrale | 1 transfer | |
Regionale 18218+ 9924 | 8:18 AM Siena station | 5h02 | 1:20 PM Milan Centrale | 1 transfer | |
Regionale 19032 · TUSCANY LINE 4030+ 9932 | 9:41 AM Siena station | 5h39 | 3:20 PM Milan Centrale | 2 transfers | |
Regionale 19032 · TUSCANY LINE 4030+ FRECCIAROSSA 1000 9514 | 9:41 AM Siena station | 4h09 | 1:50 PM Milan Centrale | 2 transfers | |
Regionale 19032 · TUSCANY LINE 4030+ 8134 | 9:41 AM Siena station | 6h39 | 4:20 PM Milan Centrale | 2 transfers | |
Regionale 19032 · TUSCANY LINE 4030+ 9928 | 9:41 AM Siena station | 4h39 | 2:20 PM Milan Centrale | 2 transfers | |
Regionale 18220+ 9932 | 10:18 AM Siena station | 5h02 | 3:20 PM Milan Centrale | 1 transfer | |
Regionale 18220+ 8134 | 10:18 AM Siena station | 6h02 | 4:20 PM Milan Centrale | 1 transfer | |
Regionale 18220+ Intercity 588 · Intercity 608 | 10:18 AM Siena station | 6h27 | 4:45 PM Milan Centrale | 2 transfers | |
Regionale 18220+ 9928 | 10:18 AM Siena station | 4h02 | 2:20 PM Milan Centrale | 1 transfer | |
Regionale 18220+ FRECCIAROSSA 9532 | 10:18 AM Siena station | 4h32 | 2:50 PM Milan Centrale | 1 transfer | |
Regionale 18220+ FRECCIAROSSA 1000 8418 · FRECCIAROSSA 1000 9632 | 10:18 AM Siena station | 4h17 | 2:35 PM Milan Centrale | 2 transfers | |
Regionale 19034 · TUSCANY LINE 4032+ 8134 | 10:45 AM Siena station | 5h35 | 4:20 PM Milan Centrale | 2 transfers | |
Regionale 19034 · TUSCANY LINE 4032+ 9940 | 10:45 AM Siena station | 6h35 | 5:20 PM Milan Centrale | 2 transfers | |
Regionale 19034 · TUSCANY LINE 4032+ 9932 | 10:45 AM Siena station | 4h35 | 3:20 PM Milan Centrale | 2 transfers | |
Regionale 19034 · TUSCANY LINE 4032+ FRECCIAROSSA 9532 | 10:45 AM Siena station | 4h05 | 2:50 PM Milan Centrale | 2 transfers | |
Regionale 18222+ FRECCIAROSSA 9584 | 11:18 AM Siena station | 4h32 | 3:50 PM Milan Centrale | 1 transfer | |
Regionale 18222+ 9932 | 11:18 AM Siena station | 4h02 | 3:20 PM Milan Centrale | 1 transfer | |
Regionale 18222+ 9940 | 11:18 AM Siena station | 6h02 | 5:20 PM Milan Centrale | 1 transfer | |
Regionale 18222+ 8134 | 11:18 AM Siena station | 5h02 | 4:20 PM Milan Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Siena to Milan Centrale by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Siena to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale or Intercity to find the best option for your trip from Siena to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Siena to Milan Centrale.
Why book with Omio over Raileurope?
- Official reseller: Italo tickets can only be bought on Omio or Italo's website as Omio is the only official third party seller for Italo tickets. Raileurope do not sell Italo tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Siena to Milan Centrale.
Journey information
Overview: Train from Siena to Milan Centrale
Trains from Siena to Milan Centrale run on average 29 times per day, taking around 4h 4m. Cheap train tickets for this journey start at $29 (€23) but you can travel from only $10 (€8) by bus.
The earliest train runs at 03:40, the last at 18:23. The fastest train covers the 182 miles (294 km) distance in 5h 36m.
Distance 182 miles (294 km) |
Average train duration 4h 4m |
Cheapest ticket price $29 (€23) |
Trains per day 29 |
Fastest train 5h 36m |
First train 03:40 |
Last train 18:23 |
Train companies: Italo, Frecciarossa, Regionale, Intercity from Siena to Milan Centrale trainsItalo, Frecciarossa, Regionale, Intercity trains will get you between Siena and Milan Centrale from $10 (€8). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Regionale
Intercity
FAQs: Trains from Siena to Milan Centrale
Find answers to the most common questions about traveling from Siena to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Siena to Milan Centrale
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Siena
More options for your journey from Siena to Milan Centrale
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