The cheapest and fastest trains from Siena to Milan Centrale
Cheapest price
$44
Average price
$86
Fastest journey
5 h 2 m
Average duration
5 h 7 m
Trains per day
58
Distance
294 km
The best way to find a cheap train ticket from Siena to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Milan Centrale will cost around $86 if you buy it on the day, but the cheapest tickets can be found for only $44.
It's difficult to get from Siena to Milan Centrale without transferring at least 2 times.
Regionale 19044 · ETRUSCHI LINE 18307 · Regionale 2596
Regionale 18224 · Regionale 18373+
Intercity 680
Regionale 18208 · Tuscany Line 4013+
Intercity 666
Regionale 18220 · Regionale 18367+
Intercity 674
Regionale 18228 · Regionale 18379+
Intercity 684
Regionale 18234 · Autobus FI148 · TUSCANY LINE 18529+
9954
Regionale 19034 · Autobus FI158+
FRECCIAROSSA 9584
Regionale 19038 · Autobus FI220+
FRECCIAROSSA 9544
Regionale 19040 · Autobus FI222+
FRECCIAROSSA 9588
Regionale 19046 · Autobus FI230+
FRECCIAROSSA 1000 9560Travel Information
Compare bus, train, and flight for Siena to Milan Centrale
Omio recommends booking the train as it is the most popular option from Siena to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a train which can get you there in 4h 4m. The ticket price range depends on the travel mode: a bus costs an average of €8, and a flight costs an average of €103.
Distance: 182 miles (294 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€37 Average price | €16 Average price Cheapest | €171 Average price |
4h 34m Average total duration Fastest 4h 4m Onboard + 30m Additional time* | 5h 28m Average total duration 4h 58m Onboard + 30m Additional time* | 12h 41m Average total duration 9h 41m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Siena to Milan Centrale train times
The table below shows live departures for Siena to Milan Centrale trains for today, Friday, November 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:15 AM Siena | 7h10 | 5:25 PM Milan Centrale | 0 transfersDirect | |
![]() | 11:18 AM Siena | 6h07 | 5:25 PM Milan Centrale | 0 transfersDirect | |
![]() | 11:30 AM Siena | 9h52 | 9:22 PM Milan Centrale | 0 transfersDirect | |
![]() | 2:02 PM Siena | 7h15 | 9:17 PM Milan Centrale | 0 transfersDirect | |
![]() | 2:41 PM Siena | 6h41 | 9:22 PM Milan Centrale | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets Siena to Milan Centrale by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 08
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Nov 11
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Nov 14
Journey information
Overview: Train from Siena to Milan Centrale
Trains from Siena to Milan Centrale run on average 29 times per day, taking around 4h 4m. Cheap train tickets for this journey start at $28 (€23) but you can travel from only $10 (€8) by bus.
The earliest train runs at 03:40, the last at 18:23. The fastest train covers the 182 miles (294 km) distance in 5h 36m.
Distance 182 miles (294 km) |
Average train duration 4h 4m |
Cheapest ticket price $28 (€23) |
Trains per day 29 |
Fastest train 5h 36m |
First train 03:40 |
Last train 18:23 |
Train companies: Italo, Frecciarossa, Regionale, Intercity from Siena to Milan Centrale trainsItalo, Frecciarossa, Regionale, Intercity trains will get you between Siena and Milan Centrale from $10 (€8). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Regionale
Intercity
FAQs: Trains from Siena to Milan Centrale
Find answers to the most common questions about traveling from Siena to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Siena to Milan Centrale
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Siena
More options for your journey from Siena to Milan Centrale
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