The cheapest and fastest trains from Siena to Milan Centrale
Cheapest price
$34
Average price
$42
Fastest journey
1 h 55 m
Average duration
5 h 31 m
Trains per day
5
Distance
294 km
The best way to find a cheap train ticket from Siena to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Milan Centrale will cost around $42 if you buy it on the day, but the cheapest tickets can be found for only $34.
Of the 5 trains that leave Siena for Milan Centrale on Thu, May 07, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 07 the direct trains cover the 294 km distance in an average of 5 h 31 m but if you time it right, some trains will get you there in just 1 h 55 m .
On Thu, May 07 the slowest trains will take 6 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:25 PM1h55Siena11:20 PMMilan Centrale$341One-way0 transfers
4:41 PM5h36Siena10:17 PMMilan Centrale$361One-way0 transfers
3:41 PM6h44Siena10:25 PMMilan Centrale$401One-way0 transfers
2:18 PM6h37Siena8:55 PMMilan Centrale$441One-way0 transfers
12:18 PM6h45Siena7:03 PMMilan Centrale$591One-way0 transfers
9:25 PM1h55Siena11:20 PMMilan Centrale$341One-way0 transfers
4:41 PM5h36Siena10:17 PMMilan Centrale$361One-way0 transfers
2:18 PM6h37Siena8:55 PMMilan Centrale$441One-way0 transfers
3:41 PM6h44Siena10:25 PMMilan Centrale$401One-way0 transfers
12:18 PM6h45Siena7:03 PMMilan Centrale$591One-way0 transfers
Travel Information
Compare bus and train for Siena to Milan Centrale
Omio recommends booking the train as it is the most popular option from Siena to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $11. For those with little time consider booking a train which can get you there in 4h 4m. The ticket price range depends on the travel mode: a bus costs an average of $11, and a train costs an average of $29.
Distance: 182 miles (294 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$41 Average price | $19 Average price Cheapest | $107 Average price (fuel + tolls) |
4h 34m Average total duration Fastest 4h 4m Onboard + 30m Additional time* | 5h 42m Average total duration 5h 12m Onboard + 30m Additional time* | 3h 44m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Siena to Milan Centrale:
A bus is $22 (€17) less than a train for this route with tickets for a train from Siena to Milan Centrale costing on average $41 (€33).
Other travel options to Milan Centrale take longer:
Bus takes on average 5h 12m.
Tickets start at around $41 (€33) compared to roughly $107 (€86) in fuel and tolls — a saving of about $66 (€53). The journey takes 4h 4m versus 3h 44m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Siena to Milan Centrale train times
The table below shows live departures for Siena to Milan Centrale trains for tomorrow, Thursday, May 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:18 PM Siena | 6h45 | 7:03 PM Milan Centrale | 0 transfersDirect | |
![]() | 2:18 PM Siena | 6h37 | 8:55 PM Milan Centrale | 0 transfersDirect | |
![]() | 3:41 PM Siena | 6h44 | 10:25 PM Milan Centrale | 0 transfersDirect | |
![]() | 4:41 PM Siena | 5h36 | 10:17 PM Milan Centrale | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Siena to Milan Centrale by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 07
May 08
May 09
May 10
May 11
May 12
May 13
May 14
May 15
May 16
May 17
May 18
May 19
May 20
Why should you book Siena to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale or Intercity to find the best option for your trip from Siena to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus and train to ensure you get the best deal for traveling from Siena to Milan Centrale.
Journey information
Overview: Train from Siena to Milan Centrale
Trains from Siena to Milan Centrale run on average 30 times per day, taking around 4h 4m. Cheap train tickets for this journey start at $29 (€23) but you can travel from only $11 (€9) by bus.
The earliest train runs at 05:25, the last at 21:25. The fastest train covers the 182 miles (294 km) distance in 1h 55m.
Distance 182 miles (294 km) |
Average train duration 4h 4m |
Cheapest ticket price $29 (€23) |
Trains per day 30 |
Fastest train 1h 55m |
First train 5:25 AM |
Last train 9:25 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Train companies: Italo, Frecciarossa, Regionale, Intercity from Siena to Milan Centrale trainsItalo, Frecciarossa, Regionale, Intercity trains will get you between Siena and Milan Centrale from $11 (€9). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Regionale
Intercity
FAQs: Trains from Siena to Milan Centrale
Find answers to the most common questions about traveling from Siena to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Siena to Milan Centrale
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Siena
More options for your journey from Siena to Milan Centrale
Here are some other resources that might have the information you need

