The cheapest and fastest trains from Prague to Grenoble
Cheapest price
$0
Average price
$-0
Fastest journey
16 h 5 m
Average duration
16 h 5 m
Trains per day
1
Distance
848 km
The best way to find a cheap train ticket from Prague to Grenoble is to book your journey as far in advance as possible and to avoid traveling at rush hour.
It's difficult to get from Prague to Grenoble without transferring at least 4 times.


Travel Information
Compare train, bus, and flight for Prague to Grenoble
Omio recommends booking the flight as it is the most popular option from Prague to Grenoble among Omio's users. If you are prioritising price take the bus with prices starting from €51. For those with little time consider booking a flight which can get you there in 2h 11m. The ticket price range depends on the travel mode: a bus costs an average of €51, and a flight costs an average of €37.
Distance: 526 miles (848 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
€104 Average price | €75 Average price Cheapest |
5h 11m Average total duration Fastest 2h 11m Onboard + 3h 0m Additional time* | 20h 16m Average total duration 19h 46m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Prague to Grenoble train times
The table below shows live departures for Prague to Grenoble trains for tomorrow, Tuesday, December 23. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:35 AM Prague | 16h05 | 9:40 PM Grenoble | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Grenoble by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 22
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Why should you book Prague to Grenoble trains with Omio?
ÖBB | Euro City (EC) operates all train services from Prague to Grenoble. Omio is the only official third party seller for ÖBB | Euro City (EC) tickets.
Why book with Omio vs ÖBB | Euro City (EC)?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare ÖBB | Euro City (EC) with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Grenoble.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: ÖBB | Euro City (EC) tickets can only be bought on Omio or ÖBB | Euro City (EC)'s website as Omio is the only official third party seller for ÖBB | Euro City (EC) tickets. Trainline, RailEurope, and Rail.Ninja do not sell ÖBB | Euro City (EC) tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Grenoble.
Journey information
Overview: Train from Prague to Grenoble
Take a train from Prague to Grenoble and enjoy the approximately 526 miles (848 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 05:35, the last at 05:35. The fastest train covers the 526 miles (848 km) distance in 16h 5m.
Distance 526 miles (848 km) |
Average train duration 16h 5m |
Trains per day 1 |
Fastest train 16h 5m |
First train 05:35 |
Last train 05:35 |
Train companies: ÖBB | Euro City (EC) from Prague to Grenoble trainsÖBB | Euro City (EC) trains will get you between Prague and Grenoble from $46 (€37). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
ÖBB | Euro City (EC)
FAQs: Trains from Prague to Grenoble
Find answers to the most common questions about traveling from Prague to Grenoble by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Grenoble, this guide helps you travel smarter and with confidence.

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