Travel Information
Compare train, bus, and flight for Pisa to Manchester
Omio recommends booking the flight as it is the most popular option from Pisa to Manchester among Omio's users. If you are prioritising price take the bus with prices starting from €76. For those with little time consider booking a flight which can get you there in 2h 44m. The ticket price range depends on the travel mode: a bus costs an average of €76, and a train costs an average of €501.
Distance: 885 miles (1425 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€501 Average price | €152 Average price | €141 Average price Cheapest |
24h 26m Average total duration 23h 56m Onboard + 30m Additional time* | 5h 44m Average total duration Fastest 2h 44m Onboard + 3h 0m Additional time* | 40h 36m Average total duration 40h 6m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Pisa to Manchester by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pisa to Manchester trains with Omio?
Regionale operates all train services from Pisa to Manchester. Omio is the only official third party seller for Regionale tickets.
Why book with Omio vs Regionale?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Regionale with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Manchester.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Regionale tickets can only be bought on Omio or Regionale's website as Omio is the only official third party seller for Regionale tickets. Trainline, RailEurope, and Rail.Ninja do not sell Regionale tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Manchester.
Journey information
Overview: Train from Pisa to Manchester
Trains from Pisa to Manchester run on average 1 times per day, taking around 23h 56m. Cheap train tickets for this journey start at $625 (€501) but you can travel from only $40 (€32) by flight.
The earliest train runs at 01:51, the last at 18:00. The fastest train covers the 885 miles (1425 km) distance in 23h 56m.
Distance 885 miles (1425 km) |
Average train duration 23h 56m |
Cheapest ticket price $625 (€501) |
Trains per day 1 |
Fastest train 23h 56m |
First train 01:51 |
Last train 18:00 |
Train companies: Regionale from Pisa to Manchester trainsRegionale trains will get you between Pisa and Manchester from $40 (€32). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
FAQs: Trains from Pisa to Manchester
Find answers to the most common questions about traveling from Pisa to Manchester by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Manchester, this guide helps you travel smarter and with confidence.

Most popular train connections from Pisa
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