The cheapest and fastest trains from Mestre to Domodossola
Cheapest price
$89
Average price
$126
Fastest journey
4 h 13 m
Average duration
4 h 39 m
Trains per day
5
Distance
314 km
The best way to find a cheap train ticket from Mestre to Domodossola is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Domodossola will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $89.
Of the 5 trains that leave Mestre for Domodossola on Thu, Nov 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct trains cover the 314 km distance in an average of 4 h 39 m but if you time it right, some trains will get you there in just 4 h 13 m .
On Thu, Nov 06 the slowest trains will take 5 h 34 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for Mestre to Domodossola
Omio recommends booking the bus as it is the most popular option from Mestre to Domodossola among Omio's users. If you are prioritising price take the bus with prices starting from €36. For those with little time consider booking a train which can get you there in 5h 48m. The ticket price range depends on the travel mode: a bus costs an average of €36, and a flight costs an average of €108.
Distance: 195 miles (314 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€53 Average price | €44 Average price Cheapest | €194 Average price |
6h 18m Average total duration Fastest 5h 48m Onboard + 30m Additional time* | 8h 57m Average total duration 8h 27m Onboard + 30m Additional time* | 13h 22m Average total duration 10h 22m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Mestre to Domodossola train times
The table below shows live departures for Mestre to Domodossola trains for today, Wednesday, November 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:28 PM Mestre | 6h36 | 9:04 PM Domodossola | 0 transfersDirect | |
| Thursday, November 6 | |||||
![]() | 8:30 AM Mestre | 7h23 | 3:53 PM Domodossola | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mestre to Domodossola by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Journey information
Overview: Train from Mestre to Domodossola
Distance 195 miles (314 km) |
Average train duration 5h 48m |
Cheapest ticket price $33 (€27) |
Trains per day 4 |
Fastest train 4h 36m |
First train 04:03 |
Last train 18:28 |
Train companies: Trenitalia EuroCity, Frecciarossa, Italo from Mestre to Domodossola trainsTrenitalia EuroCity, Frecciarossa, Italo trains will get you between Mestre and Domodossola from $33 (€27). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Trenitalia EuroCity
FAQs: Trains from Mestre to Domodossola

popular train stations
Popular train stations from Mestre to Domodossola
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available near the station, open 24/7.
- Outside the main entrance.
- €1
- Hotel Villa Sara
- Hotel Altieri
- Hotel Ducale
- Located near the main entrance
- The station has a simple layout with two platforms and a small waiting area.
- Bus: Several ACTV lines available
- Tram: Line T1
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, accessible from the main entrance.
- Ristorante La Meridiana
- Osteria Vecchio Borgo
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
- Train: Regional and Eurocity trains
- Bus: Several local lines available
Most popular train connections from Mestre
More options for your journey from Mestre to Domodossola
Here are some other resources that might have the information you need
