- Recommended
Palazzo San Francesco - Musei Civici Gian Giacomo Galletti
The city museum inside a former Franciscan complex, presenting local archaeology, art, and historical collections linked to Ossola and Domodossola.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest trains from Mestre to Domodossola
Showing times and prices for Jun 20
Cheapest price
$40
Average price
$40
Fastest journey
4 h 36 m
Average duration
4 h 36 m
Trains per day
1
Distance
314 km
Cheap tickets
The best way to find a cheap train ticket from Mestre to Domodossola is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Domodossola will cost around $40 if you buy it on the day, but the cheapest tickets can be found for only $40.
Fast trains
Of the 1 trains that leave Mestre for Domodossola on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct trains cover the 314 km distance in an average of 4 h 36 m but if you time it right, some trains will get you there in just 4 h 36 m .
On Sat, Jun 20 the slowest trains will take 4 h 36 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:28 PM4h36Mestre6:04 PMDomodossola$401One-way0 transfers
- 1:28 PM4h36Mestre6:04 PMDomodossola$401One-way0 transfers
Travel Information
Compare train, bus, and flight for Mestre to Domodossola
Omio recommends booking the train as it is the most popular option from Mestre to Domodossola among Omio's users. If you are prioritising price take the bus with prices starting from $45. For those with little time consider booking a train which can get you there in 3h 55m. The ticket price range depends on the travel mode: a bus costs an average of $45, and a flight costs an average of $147.
Distance: 195 miles (314 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$63 Average price | $45 Average price Cheapest | $147 Average price | $78 Average price (fuel + tolls) |
4h 25m Average total duration Fastest 3h 55m Onboard + 30m Additional time* | 6h 45m Average total duration 6h 15m Onboard + 30m Additional time* | 12h 55m Average total duration 9h 55m Onboard + 3h 0m Additional time* | 3h 32m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Mestre to Domodossola is a bus with an average price of $45 (€37).
This is compared to other travel options from Mestre to Domodossola:
A bus is $18 (€15) less than a train for this route with tickets for a train from Mestre to Domodossola costing on average $63 (€52).
A bus is $102 (€84) less than a flight for this route with tickets for a flight from Mestre to Domodossola costing on average $147 (€121).
The fastest way to travel from Mestre to Domodossola is by train with an average journey time of 3h 55m.
Other travel options to Domodossola take longer:
Bus takes on average 6h 15m.
Flight takes on average 9h 55m.
It's helpful to compare your options as there are 3 ways to travel between Mestre and Domodossola including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Mestre to Domodossola among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Trenitalia EuroCity.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Mestre to Domodossola train times
The table below shows live departures for Mestre to Domodossola trains for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:28 PM Mestre | 4h36 | 6:04 PM Domodossola | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mestre to Domodossola by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sat
Jun 20
Jun 20
Sun
Jun 21
Jun 21
Mon
Jun 22
Jun 22
Tue
Jun 23
Jun 23
Wed
Jun 24
Jun 24
Thu
Jun 25
Jun 25
Fri
Jun 26
Jun 26
Why should you book Mestre to Domodossola trains with Omio?
Italo as well as Trenitalia EuroCity or Frecciarossa offer trains services from Mestre to Domodossola.
Omio is the only official third party seller for Italo tickets.
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Trenitalia EuroCity or Frecciarossa to find the best option for your trip from Mestre to Domodossola.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mestre to Domodossola.
Journey information
Overview: Train from Mestre to Domodossola
ItalyItaly
Trains from Mestre to Domodossola run on average 7 times per day, taking around 3h 55m. Cheap train tickets for this journey start at $40 (€32) if you book in advance.
The earliest train runs at 04:03, the last at 18:28. The fastest train covers the 195 miles (314 km) distance in 4h 36m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 195 miles (314 km) |
Average train duration 3h 55m |
Cheapest ticket price $40 (€32) |
Trains per day 7 |
Fastest train 4h 36m |
First train 4:03 AM |
Last train 6:28 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 7 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Train companies: Italo, Trenitalia EuroCity, Frecciarossa from Mestre to Domodossola trainsItalo, Trenitalia EuroCity, Frecciarossa trains will get you between Mestre and Domodossola from $40 (€32). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
4h 34m
Cheapest Price
$151 (€124)
Italo frequency
1 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
4h 36m
Cheapest Price
$40 (€32)
Frecciarossa frequency
4 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Trenitalia EuroCity
Luggage & cancellation policy
Average Duration
4h 13m
Cheapest Price
$146 (€120)
Trenitalia EuroCity frequency
2 a day
Complete guide to Domodossola
Things to do in Domodossola
Discover the best of Domodossola — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Domodossola trip today.
Museo Sempioniano
A local history museum focused on the Simplon area, useful for understanding the Alpine routes, trade, and military history that shaped Domodossola.
Museo di Scienze Naturali Mellerio Rosmini
A small natural science museum with zoological, mineral, and botanical displays, appreciated by visitors interested in regional nature and education.
- Must visit
Piazza del Mercato
Domodossola's signature square, lined with arcades and historic buildings, famous for markets, events, and its highly photogenic old-town atmosphere.
- Must visit
Centro Storico di Domodossola
The old town is the best area for strolling, with cobbled lanes, arcades, stone houses, and a lively but compact historic core.
- Recommended
Via Briona
One of the most characteristic streets in the center, appreciated for its traditional architecture, arcaded sections, and local boutiques.
- Vegetarian
- Gluten-free
Polenta Concia
Rich mountain polenta enriched with local butter and melted alpine cheese, a classic Ossola comfort dish tied to the valleys around Domodossola.
- Gluten-free
Tapulone D'Ossola
A slow-cooked minced meat stew, traditionally flavored with wine and herbs, commonly served with polenta in the Ossola area.
- Vegetarian
Gnocchi All'ossolana
Rustic potato gnocchi prepared in local style, often with butter, cheese, and sometimes cured meat, reflecting hearty alpine cooking.
Atelier Restaurant E Bistrot
Modern dining venue in Domodossola appreciated for creative Italian cooking, careful presentation, and a more contemporary ambiance.
Ristorante La Meridiana
Established restaurant in Domodossola known for refined Piedmontese and Ossola dishes in an elegant, traditional setting.
Osteria Vecchio Borgo
Well-regarded casual spot serving regional mountain cuisine, local wines, and classic comfort dishes in a warm historic atmosphere.
Euro
Generally moderate by Italian standards: coffee and casual meals are reasonable, while hotel and tourist-area prices can be higher.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or a simple lunch.
- Mid-range
- EUR 20-35 per person for a standard restaurant meal.
- Fine dining
- EUR 50-90 per person at upscale restaurants.
- Coffee
- EUR 1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or covered by a coperto. Tipping is not obligatory; round up or leave EUR 1-2 at cafes, 5-10% for excellent restaurant service, and round up taxis.
MooneyGo
Get the appOfficial public transport app
Prices
- Single ticket
- 1.50 EUR
- Day pass
- None
To the city center
Domodossola Railway Station, Domodossola -> Piazza del Mercato, Domodossola
- Distance
- 0.6 km
- Travel time
- 8 min
- Urban buses in Domodossola are operated by VCO Trasporti; check route and timetable updates before travel in the official app or on the operator website.
- On local buses, buying tickets before boarding is recommended; card payment on board is not consistently available.
FAQs: Trains from Mestre to Domodossola
Find answers to the most common questions about traveling from Mestre to Domodossola by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Domodossola, this guide helps you travel smarter and with confidence.
Train ticket prices from Mestre to Domodossola can vary. The cheapest ticket starts at $40 (€32), while the average price is around $63 (€52).
The train from Mestre to Domodossola takes 4h 36m and runs 7 per day.
The first train from Mestre to Domodossola leaves at 4:03 AM.
The distance by train from Mestre to Domodossola is 195 miles (314 km).
The last train from Mestre to Domodossola leaves at 6:28 PM.
Yes, there is a high-speed train from Mestre to Domodossola.
Yes, there is a direct train from Mestre to Domodossola. This service operates 0 times per day, provided by Trenitalia EuroCity.
Unfortunately, there is no night train available from Mestre to Domodossola.
The train station in Mestre that goes to Domodossola is Venezia Mestre Ospedale, which connects to Domodossola station.
The cheapest way to get from Mestre to Domodossola is by train, with a cost of around $40 (€32).
Yes, the train journey from Mestre to Domodossola is scenic, as it traverses through picturesque landscapes including the Italian countryside, Alpine foothills, and charming towns, offering travelers stunning views along the way.
A day trip from Mestre to Domodossola is not feasible as the journey takes 4h 36m. There are 4 train trips available per day.
In Domodossola, visitors can enjoy skiing and snowboarding at the Domobianca Ski Resort during winter. The town offers a rich cultural experience with guided tours of the historic town center and exploration of local markets and shops for unique Italian goods. Notable sights include the Piazza del Mercato, Sacro Monte Calvario, Palazzo Silva, and the Collegiate Church of Saints Gervasius and Protasius. Nature enthusiasts can hike in the surrounding mountains and the Val Grande National Park. Additionally, visiting local wineries provides an opportunity to taste regional wines and learn about winemaking.
A stay of 2 to 3 days in Domodossola is ideal to explore its historic town center, enjoy the local cuisine, and take day trips to nearby attractions such as the Sacro Monte Calvario and the scenic routes of the Ossola Valley.
Yes, you can take the train from Mestre to Domodossola.
Since both Mestre and Domodossola are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Domodossola include Milan, Zermatt, Brig-Glis, Stresa, Interlaken.
We recommend using the train as it is the most popular way to get from Mestre to Domodossola among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Domodossola, travelers should be mindful of typical urban safety concerns such as pickpocketing, especially in crowded areas like markets and train stations. It is advisable to keep personal belongings secure and avoid displaying valuables openly. Scams are relatively rare, but travelers should be cautious of unofficial taxi drivers or overly persistent street vendors. Staying aware of surroundings and using licensed services helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Mestre to Domodossola
Mestre
Domodossola
The major train station for departures in Mestre is Venezia Mestre Ospedale. Find all the information you need to know about services, amenities and connections at Venezia Mestre Ospedale for your trip from Mestre to Domodossola.
Amenities at train station
Parking
Dining
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Information Deskinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
2 km
Number of platforms
2Parking
- Parking is available near the station, open 24/7
Taxis
- Outside the main entrance
WC
- €1
Hotel
- Hotel Villa Sara
- Hotel Altieri
- Hotel Ducale
Information Desk
- Located near the main entrance
Station Plan
- The station has a simple layout with two platforms and a small waiting area.
Public transit options for Venezia Mestre Ospedale
- Bus: Several ACTV lines available
- Tram: Line T1
The major train station for arrivals in Domodossola is Domodossola. Find all the information you need to know about services, amenities and connections at Domodossola for your journey to Domodossola from Mestre.
Amenities at train station
Wifi
LockersParkingDining
ATMTaxisAccessibilityWCHotel
Lost and Found OfficeTicket OfficeBike Parking
Car RentalInformation Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 8:00 PM Monday - Sunday
Number of platforms
5Wifi
- Free
Parking
- The car park is open 7 days a week, accessible from the main entrance
Dining
- Ristorante La Meridiana
- Osteria Vecchio Borgo
Taxis
- Outside the main entrance
Accessibility
- Elevators, ramps
WC
- €1
Hotel
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
Public transit options for Domodossola
- Train: Regional and Eurocity trains
- Bus: Several local lines available
Most popular train connections from Mestre
More options for your journey from Mestre to Domodossola
Here are some other resources that might have the information you need
Most popular trains to and from Domodossola and Mestre
Most popular train connections to Domodossola
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
