The cheapest and fastest trains from Mestre to Domodossola
Cheapest price
$95
Average price
$118
Fastest journey
4 h 13 m
Average duration
4 h 26 m
Trains per day
5
Distance
314 km
The best way to find a cheap train ticket from Mestre to Domodossola is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Domodossola will cost around $118 if you buy it on the day, but the cheapest tickets can be found for only $95.
Of the 5 trains that leave Mestre for Domodossola on Sun, Mar 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct trains cover the 314 km distance in an average of 4 h 26 m but if you time it right, some trains will get you there in just 4 h 13 m .
On Sun, Mar 22 the slowest trains will take 4 h 34 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for Mestre to Domodossola
Omio recommends booking the train as it is the most popular option from Mestre to Domodossola among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a train which can get you there in 3h 55m. The ticket price range depends on the travel mode: a bus costs an average of $43, and a flight costs an average of $132.
Distance: 195 miles (314 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$56 Average price | $177 Average price | $53 Average price Cheapest |
4h 25m Average total duration Fastest 3h 55m Onboard + 30m Additional time* | 10h 30m Average total duration 7h 30m Onboard + 3h 0m Additional time* | 8h 57m Average total duration 8h 27m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Mestre to Domodossola train times
The table below shows live departures for Mestre to Domodossola trains for today, Saturday, March 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:00 PM Mestre | 4h43 | 4:43 PM Domodossola | 1 transfer | |
| Sunday, March 22 | |||||
![]() | 6:30 AM Mestre | 4h39 | 11:09 AM Domodossola | 1 transfer | |
![]() | 8:09 AM Mestre | 4h34 | 12:43 PM Domodossola | 1 transfer | |
![]() | 8:30 AM Mestre | 5h23 | 1:53 PM Domodossola | 1 transfer | |
![]() | 9:09 AM Mestre | 5h34 | 2:43 PM Domodossola | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Mestre to Domodossola by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Mestre to Domodossola trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Trenitalia EuroCity or Frecciarossa to find the best option for your trip from Mestre to Domodossola.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mestre to Domodossola.
Journey information
Overview: Train from Mestre to Domodossola
Trains from Mestre to Domodossola run on average 6 times per day, taking around 3h 55m. Cheap train tickets for this journey start at $40 (€32) if you book in advance.
The earliest train runs at 04:03, the last at 17:56. The fastest train covers the 195 miles (314 km) distance in 4h 36m.
Distance 195 miles (314 km) |
Average train duration 3h 55m |
Cheapest ticket price $40 (€32) |
Trains per day 6 |
Fastest train 4h 36m |
First train 04:03 |
Last train 17:56 |
Cheapest month Oct |
Cheapest day Sat |
High season Oct - Dec |
Low season Jan - Mar |
Busiest day Thu |
Least busy day Thu |
Best day to book ahead 7 days |
Train companies: Italo, Trenitalia EuroCity, Frecciarossa from Mestre to Domodossola trainsItalo, Trenitalia EuroCity, Frecciarossa trains will get you between Mestre and Domodossola from $40 (€32). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Trenitalia EuroCity
FAQs: Trains from Mestre to Domodossola
Find answers to the most common questions about traveling from Mestre to Domodossola by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Domodossola, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mestre to Domodossola
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available near the station, open 24/7.
- Outside the main entrance.
- €1
- Hotel Villa Sara
- Hotel Altieri
- Hotel Ducale
- Located near the main entrance
- The station has a simple layout with two platforms and a small waiting area.
- Bus: Several ACTV lines available
- Tram: Line T1
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, accessible from the main entrance.
- Ristorante La Meridiana
- Osteria Vecchio Borgo
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
- Train: Regional and Eurocity trains
- Bus: Several local lines available
Most popular train connections from Mestre
More options for your journey from Mestre to Domodossola
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