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The cheapest and fastest trains from Mestre to Rome
Showing times and prices for Mar 22
Cheapest price
$65
Average price
$99
Fastest journey
4 h 7 m
Average duration
4 h 53 m
Trains per day
9
Distance
400 km
Cheap tickets
The best way to find a cheap train ticket from Mestre to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Rome will cost around $99 if you buy it on the day, but the cheapest tickets can be found for only $65.
Fast trains
It's difficult to get from Mestre to Rome without transferring at least once.
Regionale 16831+
InterCityNotte 77009:26PM9h09
Venezia Mestre Ospedale06:35AMRome Termini
$651One-way
1 transfer
Regionale 16825 · Regionale 33691+InterCityNotte 76308:28PM9h38
Venezia Mestre Ospedale06:06AMRome Termini
$721One-way
2 transfers
Regionale 16811+
Intercity 58408:36AM7h44
Venezia Mestre Ospedale04:20PMRome Termini
$731One-way
1 transfer
Regionale 16777 · Regionale Veloce 3975+Intercity 59712:26PM8h54
Venezia Mestre Ospedale09:20PMRome Ostiense
$781One-way
2 transfers
Regionale 16811 · Regionale Veloce 3967+
FRECCIAROSSA 931108:36AM5h48
Venezia Mestre Ospedale02:24PMRome Termini
$1021One-way
2 transfers
Regionale 16238+FRECCIAROSSA 946607:58AM4h07
Venezia Mestre Ospedale12:05PMRome Termini
$1261One-way
1 transfer
Regionale 16037+FRECCIAROSSA 940105:20AM4h13
Venezia Mestre Ospedale09:33AMRome Termini
$1261One-way
1 transfer
Regionale 16812 · Regionale Veloce 3665+FRECCIAROSSA 943505:34PM4h51
Venezia Mestre Ospedale10:25PMRome Termini
$1261One-way
2 transfers
Regionale 16680+FRECCIAROSSA 1000 941309:58AM5h27
Venezia Mestre Ospedale03:25PMRome Termini
$1261One-way
1 transfer
Regionale 16811 · Regionale Veloce 3967+FRECCIAROSSA 931108:36AM5h48
Venezia Mestre Ospedale02:24PMRome Termini
$1021One-way
2 transfers
Travel Information
Compare train, bus, and flight for Mestre to Rome
Omio recommends booking the train as it is the most popular option from Mestre to Rome among Omio's users. If you are prioritising price take the train with prices starting from $28. For those with little time consider booking a flight which can get you there in 1h 9m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a train costs an average of $28, and a flight costs an average of $49.
Distance: 248 miles (400 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$60 Average price Cheapest | $67 Average price | $208 Average price |
6h 38m Average total duration 6h 8m Onboard + 30m Additional time* | 7h 20m Average total duration 6h 50m Onboard + 30m Additional time* | 4h 9m Average total duration Fastest 1h 9m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.4kg CO2 emissions |
Most popular train company |  Most popular bus company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mestre to Rome train times
The table below shows live departures for Mestre to Rome trains for today, Saturday, March 21. You can also manually refresh the results below to see updated train journeys.
Last updated at 6:49 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| Regionale 16825 · Regionale 33691+InterCityNotte 763 | 7:28 PM Venezia Mestre Ospedale | 9h38 | 5:06 AM Rome Termini | 2 transfers | |
| Regionale 16825+InterCityNotte 770 | 7:28 PM Venezia Mestre Ospedale | 10h07 | 5:35 AM Rome Termini | 1 transfer | |
| Regionale 16826 · Regionale Veloce 3898+InterCityNotte 770 | 8:02 PM Venezia Mestre Ospedale | 9h33 | 5:35 AM Rome Termini | 2 transfers | |
| Sunday, March 22 | |||||
| Regionale 16037+FRECCIAROSSA 9401 | 4:20 AM Venezia Mestre Ospedale | 4h13 | 8:33 AM Rome Termini | 1 transfer | |
| Regionale 16238+FRECCIAROSSA 9466 | 6:58 AM Venezia Mestre Ospedale | 4h07 | 11:05 AM Rome Termini | 1 transfer | |
| Regionale 16811+Intercity 584 | 7:36 AM Venezia Mestre Ospedale | 7h44 | 3:20 PM Rome Termini | 1 transfer | |
| Regionale 16811 · Regionale Veloce 3967+FRECCIAROSSA 9311 | 7:36 AM Venezia Mestre Ospedale | 5h48 | 1:24 PM Rome Termini | 2 transfers | |
| Regionale 16680+FRECCIAROSSA 1000 9413 | 8:58 AM Venezia Mestre Ospedale | 5h27 | 2:25 PM Rome Termini | 1 transfer | |
| Regionale 16777 · Regionale Veloce 3975+Intercity 597 | 11:26 AM Venezia Mestre Ospedale | 8h54 | 8:20 PM Rome Ostiense | 2 transfers | |
| Regionale 16812 · Regionale Veloce 3665+FRECCIAROSSA 9435 | 4:34 PM Venezia Mestre Ospedale | 4h51 | 9:25 PM Rome Termini | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Mestre to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Mestre to Rome trains with Omio?
Frecciarossa as well as Italo, Intercity Notte, Intercity, Regionale and more offer trains services from Mestre to Rome.
Omio is an official ticket reseller for all your travel options from Mestre to Rome.
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Intercity Notte, Intercity or Regionale to find the best option for your trip from Mestre to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mestre to Rome.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Mestre to Rome.
How far in advance should I book train tickets from Mestre to Rome?
The best time to book your train from Mestre to Rome is 63 days before departure. See how prices for trains change on the Mestre to Rome route.
Prices are for one-way tickets for one passenger from Mestre to Rome per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Mestre to Rome.
Trains
from $34Buses
from $11Flights
from $79Journey information
Overview: Train from Mestre to Rome
ItalyItaly
Trains from Mestre to Rome run on average 25 times per day, taking around 6h 8m. Cheap train tickets for this journey start at $28 (€22) but you can travel from only $21 (€17) by bus.
There are 2 trains per day. The earliest train runs at 00:15, the last at 23:49. The fastest train covers the 248 miles (400 km) distance in 3h 37m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $21 (€17)
Distance 248 miles (400 km) |
Average train duration 6h 8m |
Cheapest ticket price $28 (€22) |
Trains per day 25 |
Direct trains 2 |
Fastest train 3h 37m |
First train 00:15 |
Last train 23:49 |
Cheapest month Aug |
Cheapest day Sun |
High season Apr - Jun |
Low season Jan - Mar |
Busiest day Fri |
Least busy day Thu |
Best day to book ahead 77 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $21 (€17)
Train companies: Frecciarossa, Italo, Intercity Notte, Intercity, Regionale from Mestre to Rome trainsFrecciarossa, Italo, Intercity Notte, Intercity, Regionale trains will get you between Mestre and Rome from $21 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
3h 31m
Cheapest Price
$105 (€85)
Frecciarossa frequency
14 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Italo
About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
3h 37m
Cheapest Price
$53 (€43)
Italo frequency
8 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Intercity Notte
About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Average Duration
8h 18m
Cheapest Price
$28 (€22)
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
7h 22m
Cheapest Price
$29 (€23)
Intercity frequency
2 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
9h 52m
Cheapest Price
$61 (€49)
Regionale frequency
2 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
FAQs: Trains from Mestre to Rome
Find answers to the most common questions about traveling from Mestre to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.
Train ticket prices from Mestre to Rome can vary. The cheapest ticket starts at $28 (€22), while the average price is around $60 (€48).
The train from Mestre to Rome takes 3h 37m and runs 25 per day.
The first train from Mestre to Rome leaves at 12:15 AM.
The distance by train from Mestre to Rome is 248 miles (400 km).
The last train from Mestre to Rome leaves at 11:49 PM.
Yes, there is a high-speed train from Mestre to Rome.
Yes, there is a direct train from Mestre to Rome. This service operates 2 times per day, provided by Frecciarossa, Italo, Intercity.
Yes, there is a night train from Mestre to Rome.
The train station in Mestre that goes to Rome is Venezia Mestre Ospedale, which connects to Rome Termini.
The cheapest way to get from Mestre to Rome is by bus, with a cost of around $21 (€17).
The train journey from Mestre to Rome offers scenic views primarily in the first half, as it passes through picturesque vineyards and rolling hills of the Veneto and Emilia-Romagna regions. However, the landscape becomes more urban and industrial closer to Rome.
A day trip from Mestre to Rome is not feasible as the journey takes 3h 37m. The distance is 248 miles (400 km). Trains run 24 times per day.
In Rome, explore Trastevere's charming streets and nightlife, stroll through Villa Borghese's parks and museums, enjoy gelato at the lively Piazza Navona, and visit the Spanish Steps for views and people-watching. Discover the ancient Catacombs with guided tours, and don't miss the best sights: the iconic Colosseum, the art-filled Vatican Museums including the Sistine Chapel, the ruins of the Roman Forum, the well-preserved Pantheon, and the famous Trevi Fountain where you can toss a coin for good luck.
To experience Rome's main attractions, a stay of 3 to 4 days is generally recommended, allowing time to visit landmarks like the Colosseum, Vatican City, and explore local neighborhoods.
Yes, you can take the train from Mestre to Rome.
popular train stations
Popular train stations from Mestre to Rome
Mestre
Rome
The major train station for departures in Mestre is Venezia Mestre Ospedale. Find all the information you need to know about services, amenities and connections at Venezia Mestre Ospedale for your trip from Mestre to Rome.
Amenities at train station
Parking
Dining
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Information Deskinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
2 km
Number of platforms
2Parking
- Parking is available near the station, open 24/7.
Taxis
- Outside the main entrance.
WC
- €1
Hotel
- Hotel Villa Sara
- Hotel Altieri
- Hotel Ducale
Information Desk
- Located near the main entrance
Station Plan
- The station has a simple layout with two platforms and a small waiting area.
Public transit options for Venezia Mestre Ospedale
- Bus: Several ACTV lines available
- Tram: Line T1
The major train station for arrivals in Rome is Roma Termini. Find all the information you need to know about services, amenities and connections at Roma Termini for your journey to Rome from Mestre.
Amenities at train station
Wifi
LockersParkingDining
ATMTaxisAccessibilityWCHotelTicket OfficeBike Parking
Car RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 06:30 - 22:00
Distance to city center
1 kmWifi
- Free WiFi in the station.
Lockers
- Provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Dining
- Acafe
- Moka Café
- Roadhouse Grill
- McDonald's
- Gusto
- Chef Express
- Coop Minimarket
- Mercato Centrale
Accessibility
- The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Hotel
- Archi di Roma Guest House
- Gemma di Roma
- The Liberty Boutique Hotel
Ticket Office
- Mon - Sun: 06:30 - 22:00
Information Desk
- Located near Platform 24.
Public transit options for Roma Termini
- Metro lines: A (red), B (blue)
- Bus lines: 5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
- Tram lines: 5, 14
- Train lines: Italo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 06:35 - 20:20
Distance to city center
4 kmWifi
- Free, limited Wi-Fi available in the station for 15 minutes.
Lockers
- Luggage lockers are located in the station lobby.
Dining
- Rock n’ Coffee Roma
- Arabian Kebab
- Ingredienti
- McDonald’s
- Numb's Bakery Café
Accessibility
- Accessible facilities include elevators and escalators.
Hotel
- B&B Rome Tiburtina
- B&B Alba Domus Roma
- Hotel delle Province
Ticket Office
- Mon - Sun: 06:35 - 20:20
Information Desk
- Located inside the main terminal.
Public transit options for Roma Tiburtina
- Metro lines: LB
- Bus lines: 62, 71, 111, 111F, 120F, 135, 163, 168, 211, 309, 409, n409, n041, C2, C3, Airport Shuttle
- Train lines: FR, FA, IC, REG, FL1, FL2, FL3
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotel
Lost and Found OfficeTicket OfficeBike ParkingCar RentalInformation Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
2 kmNumber of platforms
11Wifi
- Free
Parking
- Parking is available near the station with both short-term and long-term options.
Dining
- Ramen Bar Akira
- Eataly Roma
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps, restrooms.
WC
- €1
Hotel
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
Public transit options for Roma Ostiense
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
Most popular train connections from Mestre
More options for your journey from Mestre to Rome
Here are some other resources that might have the information you need
Most popular trains to and from Rome and Mestre
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