The cheapest and fastest trains from Mestre to Rome
Cheapest price
$66
Average price
$112
Fastest journey
4 h 7 m
Average duration
4 h 18 m
Trains per day
29
Distance
400 km
The best way to find a cheap train ticket from Mestre to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Rome will cost around $112 if you buy it on the day, but the cheapest tickets can be found for only $66.
It's difficult to get from Mestre to Rome without transferring at least once.
Regionale 16831+
InterCityNotte 770
Regionale 16791+
Intercity 594
Regionale 16775+
Intercity 584
Regionale 16037 · Regionale Veloce 3961+
Intercity 583
Regionale 16781 · Regionale Veloce 3977+
Intercity 597
Regionale 16870+
FRECCIAROSSA 9466
Regionale 16037+
FRECCIAROSSA 9401
Regionale 16836 · Regionale Veloce 3637+
FRECCIAROSSA 9405
Regionale 16757+
FRECCIAROSSA 9405
Regionale 16779+
FRECCIAROSSA 9421Travel Information
Compare train, bus, and flight for Mestre to Rome
Omio recommends booking the bus as it is the most popular option from Mestre to Rome among Omio's users. If you are prioritising price take the train with prices starting from €28. For those with little time consider booking a flight which can get you there in 1h 9m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a train costs an average of €28, and a flight costs an average of €50.
Distance: 248 miles (400 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€52 Average price Cheapest | €57 Average price | €151 Average price |
6h 5m Average total duration 5h 35m Onboard + 30m Additional time* | 7h 8m Average total duration 6h 38m Onboard + 30m Additional time* | 4h 9m Average total duration Fastest 1h 9m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.4kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mestre to Rome train times
The table below shows live departures for Mestre to Rome trains for today, Sunday, December 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 16811+ Intercity 584 | 7:36 AM Venezia Mestre Ospedale | 7h44 | 3:20 PM Rome Termini | 1 transfer | |
Regionale 16811 · Regionale Veloce 3967+ FRECCIAROSSA 1000 9619 | 7:36 AM Venezia Mestre Ospedale | 4h34 | 12:10 PM Rome Termini | 2 transfers | |
Regionale 16811+ FRECCIAROSSA 1000 9411 | 7:36 AM Venezia Mestre Ospedale | 4h54 | 12:30 PM Rome Termini | 1 transfer | |
Regionale 16680+ FRECCIAROSSA 1000 9413 | 8:58 AM Venezia Mestre Ospedale | 4h27 | 1:25 PM Rome Termini | 1 transfer | |
Regionale 17277+ FRECCIAROSSA 1000 9415 | 9:26 AM Venezia Mestre Ospedale | 5h04 | 2:30 PM Rome Termini | 1 transfer | |
Regionale 17277 · Regionale Veloce 3971+ FRECCIAROSSA 1000 9627 | 9:26 AM Venezia Mestre Ospedale | 4h44 | 2:10 PM Rome Termini | 2 transfers | |
Regionale 16232+ FRECCIAROSSA 1000 8419 | 10:58 AM Venezia Mestre Ospedale | 4h26 | 3:24 PM Rome Termini | 1 transfer | |
Regionale 16777 · Regionale Veloce 3975+ Intercity 597 | 11:26 AM Venezia Mestre Ospedale | 8h41 | 8:07 PM Rome Tiburtina | 2 transfers | |
Regionale 16777 · Regionale Veloce 3975+ FRECCIAROSSA 1000 9637 | 11:26 AM Venezia Mestre Ospedale | 4h44 | 4:10 PM Rome Termini | 2 transfers | |
Regionale 16777+ FRECCIAROSSA 9421 | 11:26 AM Venezia Mestre Ospedale | 4h58 | 4:24 PM Rome Termini | 1 transfer | |
Regionale 16787+ FRECCIAROSSA 1000 9427 | 1:28 PM Venezia Mestre Ospedale | 4h57 | 6:25 PM Rome Termini | 1 transfer | |
Regionale 16787 · Regionale Veloce 3979+ FRECCIAROSSA 1000 9645 | 1:28 PM Venezia Mestre Ospedale | 4h47 | 6:15 PM Rome Termini | 2 transfers | |
Regionale 16787+ Intercity 594 | 1:28 PM Venezia Mestre Ospedale | 7h52 | 9:20 PM Rome Termini | 1 transfer | |
Regionale 16768+ FRECCIAROSSA 1000 9431 | 2:58 PM Venezia Mestre Ospedale | 4h27 | 7:25 PM Rome Termini | 1 transfer | |
Regionale 16801 · Regionale Veloce 3983+ FRECCIAROSSA 1000 9653 | 3:28 PM Venezia Mestre Ospedale | 4h42 | 8:10 PM Rome Termini | 2 transfers | |
Regionale 16801+ FRECCIAROSSA 1000 9433 | 3:28 PM Venezia Mestre Ospedale | 5h02 | 8:30 PM Rome Termini | 1 transfer | |
Regionale 16812 · Regionale Veloce 3665+ FRECCIAROSSA 9435 | 4:34 PM Venezia Mestre Ospedale | 4h51 | 9:25 PM Rome Termini | 2 transfers | |
Regionale 16258+ FRECCIAROSSA 1000 9437 | 5:58 PM Venezia Mestre Ospedale | 4h32 | 10:30 PM Rome Termini | 1 transfer | |
Regionale 16825 · Regionale Veloce 3518+ InterCityNotte 763 | 7:28 PM Venezia Mestre Ospedale | 9h38 | 5:06 AM Rome Termini | 2 transfers | |
Regionale 16831+ InterCityNotte 770 | 8:26 PM Venezia Mestre Ospedale | 9h09 | 5:35 AM Rome Termini | 1 transfer | |
Regionale 16037 · Regionale Veloce 3961+ Intercity 583 | 4:20 AM Venezia Mestre Ospedale | 8h07 | 12:27 PM Rome Tiburtina | 2 transfers | |
Regionale 16037+ FRECCIAROSSA 9401 | 4:20 AM Venezia Mestre Ospedale | 4h13 | 8:33 AM Rome Termini | 1 transfer | |
Regionale 16845+ FRECCIAROSSA 9403 | 4:58 AM Venezia Mestre Ospedale | 4h27 | 9:25 AM Rome Termini | 1 transfer | |
Regionale 16121+ FRECCIAROSSA 8801 · FRECCIAROSSA 1000 9611 | 5:26 AM Venezia Mestre Ospedale | 4h44 | 10:10 AM Rome Termini | 2 transfers | |
Regionale 16757+ FRECCIAROSSA 9405 | 5:58 AM Venezia Mestre Ospedale | 4h24 | 10:22 AM Rome Termini | 1 transfer | |
Regionale 16836 · Regionale Veloce 3637+ FRECCIAROSSA 9405 | 6:02 AM Venezia Mestre Ospedale | 4h20 | 10:22 AM Rome Termini | 2 transfers | |
Regionale 16870+ FRECCIAROSSA 9466 | 6:58 AM Venezia Mestre Ospedale | 4h07 | 11:05 AM Rome Termini | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mestre to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 22
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Why should you book Mestre to Rome trains with Omio?
Frecciarossa as well as Italo, Intercity Notte and Intercity offer trains services from Mestre to Rome. Omio is an official ticket reseller for all your travel options from Mestre to Rome.
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Intercity Notte and Intercity to find the best option for your trip from Mestre to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mestre to Rome.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Frecciarossa tickets can be bought on Frecciarossa's website or third party sellers, Omio allows you to compare with the likes of Italo, Intercity Notte and Intercity to help you choose the right option for your journey from Mestre to Rome.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Mestre to Rome.
How far in advance should I book train tickets from Mestre to Rome?
Journey information
Overview: Train from Mestre to Rome
Trains from Mestre to Rome run on average 24 times per day, taking around 5h 35m. Cheap train tickets for this journey start at $35 (€28) if you book in advance.
There are 2 trains per day. The earliest train runs at 00:02, the last at 23:49. The fastest train covers the 248 miles (400 km) distance in 4h 44m.
Distance 248 miles (400 km) |
Average train duration 5h 35m |
Cheapest ticket price $35 (€28) |
Trains per day 24 |
Direct trains 2 |
Fastest train 4h 44m |
First train 00:02 |
Last train 23:49 |
Train companies: Frecciarossa, Italo, Intercity Notte, Intercity, Frecciargento, Regionale from Mestre to Rome trainsFrecciarossa, Italo, Intercity Notte, Intercity, Frecciargento, Regionale trains will get you between Mestre and Rome from $35 (€28). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Intercity Notte
Intercity
Frecciargento
Regionale
FAQs: Trains from Mestre to Rome
Find answers to the most common questions about traveling from Mestre to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mestre to Rome
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available near the station, open 24/7.
- Outside the main entrance.
- €1
- Hotel Villa Sara
- Hotel Altieri
- Hotel Ducale
- Located near the main entrance
- The station has a simple layout with two platforms and a small waiting area.
- Bus: Several ACTV lines available
- Tram: Line T1
- Mon - Sun: 06:30 - 22:00
- Free WiFi in the station.
- Provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
- Acafe
- Moka Café
- Roadhouse Grill
- McDonald's
- Gusto
- Chef Express
- Coop Minimarket
- Mercato Centrale
- The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
- Archi di Roma Guest House
- Gemma di Roma
- The Liberty Boutique Hotel
- Mon - Sun: 06:30 - 22:00
- Located near Platform 24.
- Metro lines: A (red), B (blue)
- Bus lines: 5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
- Tram lines: 5, 14
- Train lines: Italo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
- Mon - Sun: 06:35 - 20:20
- Free, limited Wi-Fi available in the station for 15 minutes.
- Luggage lockers are located in the station lobby.
- Rock n’ Coffee Roma
- Arabian Kebab
- Ingredienti
- McDonald’s
- Numb's Bakery Café
- Accessible facilities include elevators and escalators.
- B&B Rome Tiburtina
- B&B Alba Domus Roma
- Hotel delle Province
- Mon - Sun: 06:35 - 20:20
- Located inside the main terminal.
- Metro lines: LB
- Bus lines: 62, 71, 111, 111F, 120F, 135, 163, 168, 211, 309, 409, n409, n041, C2, C3, Airport Shuttle
- Train lines: FR, FA, IC, REG, FL1, FL2, FL3
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
Most popular train connections from Mestre
More options for your journey from Mestre to Rome
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