The cheapest and fastest trains from Mestre to Florence Santa Maria Novella
Cheapest price
$33
Average price
$79
Fastest journey
2 h 19 m
Average duration
2 h 36 m
Trains per day
19
Distance
206 km
The best way to find a cheap train ticket from Mestre to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Florence Santa Maria Novella will cost around $79 if you buy it on the day, but the cheapest tickets can be found for only $33.
It's difficult to get from Mestre to Florence Santa Maria Novella without transferring at least once.
Regionale 16809 · Regionale Veloce 3985 · Regionale 178515:26 PM4h44Venezia Mestre Ospedale10:10 PMFlorence Santa Maria Novella$331One-way2 transfers
Regionale 16809 · Regionale Veloce 3985+
Intercity 5995:26 PM3h56Venezia Mestre Ospedale9:22 PMFlorence Santa Maria Novella$401One-way2 transfers
Regionale 16791+
Intercity 594+
Regionale 183122:58 PM3h45Venezia Mestre Ospedale6:43 PMFlorence Santa Maria Novella$481One-way2 transfers
Regionale 16775+
Intercity 584+
Regionale Veloce 404212:26 PM4h07Venezia Mestre Ospedale4:33 PMFlorence Santa Maria Novella$481One-way2 transfers
Regionale 16757+
FRECCIAROSSA 94056:58 AM2h41Venezia Mestre Ospedale9:39 AMFlorence Santa Maria Novella$891One-way1 transfer
Regionale 16037+
FRECCIAROSSA 94015:20 AM2h19Venezia Mestre Ospedale7:39 AMFlorence Santa Maria Novella$891One-way1 transfer
Regionale 16836 · Regionale Veloce 3637+
FRECCIAROSSA 94057:02 AM2h37Venezia Mestre Ospedale9:39 AMFlorence Santa Maria Novella$891One-way2 transfers
Regionale 16757+
FRECCIAROSSA 94056:58 AM2h41Venezia Mestre Ospedale9:39 AMFlorence Santa Maria Novella$891One-way1 transfer
Regionale 16783+
FRECCIAROSSA 94251:58 PM2h41Venezia Mestre Ospedale4:39 PMFlorence Santa Maria Novella$891One-way1 transfer
Regionale 16232+
FRECCIAROSSA 841911:58 AM2h41Venezia Mestre Ospedale2:39 PMFlorence Santa Maria Novella$891One-way1 transfer
Travel Information
Compare bus and train for Mestre to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Mestre to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from $8. For those with little time consider booking a train which can get you there in 2h 42m. The ticket price range depends on the travel mode: a bus costs an average of $8, and a train costs an average of $19.
Distance: 128 miles (206 km)
Compare train with
Most popular Train | Bus |
|---|---|
$38 Average price | $18 Average price Cheapest |
3h 12m Average total duration Fastest 2h 42m Onboard + 30m Additional time* | 4h 11m Average total duration 3h 41m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Mestre to Florence Santa Maria Novella train times
The table below shows live departures for Mestre to Florence Santa Maria Novella trains for today, Wednesday, May 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 16783+ FRECCIAROSSA 9425 | 1:58 PM Venezia Mestre Ospedale | 2h41 | 4:39 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 16791+ Intercity 594+ Regionale 18312 | 2:58 PM Venezia Mestre Ospedale | 3h45 | 6:43 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 16791+ FRECCIAROSSA 9427 | 2:58 PM Venezia Mestre Ospedale | 2h41 | 5:39 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 16768+ FRECCIAROSSA 9431 | 3:58 PM Venezia Mestre Ospedale | 2h41 | 6:39 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 16805+ FRECCIAROSSA 9433 | 4:58 PM Venezia Mestre Ospedale | 2h41 | 7:39 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 16809 · Regionale Veloce 3985+ Intercity 599 | 5:26 PM Venezia Mestre Ospedale | 3h56 | 9:22 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 16809 · Regionale Veloce 3985 · Regionale 17851 | 5:26 PM Venezia Mestre Ospedale | 4h44 | 10:10 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 16852+ FRECCIAROSSA 9435 | 5:58 PM Venezia Mestre Ospedale | 2h41 | 8:39 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 16258+ FRECCIAROSSA 9437 | 6:58 PM Venezia Mestre Ospedale | 2h41 | 9:39 PM Florence Santa Maria Novella | 1 transfer | |
| Thursday, May 7 | |||||
Regionale 16037+ FRECCIAROSSA 9401 | 5:20 AM Venezia Mestre Ospedale | 2h19 | 7:39 AM Florence Santa Maria Novella | 1 transfer | |
Regionale 16845+ FRECCIAROSSA 9403 | 5:58 AM Venezia Mestre Ospedale | 2h41 | 8:39 AM Florence Santa Maria Novella | 1 transfer | |
Regionale 16757+ FRECCIAROSSA 9405 | 6:58 AM Venezia Mestre Ospedale | 2h41 | 9:39 AM Florence Santa Maria Novella | 1 transfer | |
Regionale 16836 · Regionale Veloce 3637+ FRECCIAROSSA 9405 | 7:02 AM Venezia Mestre Ospedale | 2h37 | 9:39 AM Florence Santa Maria Novella | 2 transfers | |
Regionale 16870+ FRECCIAROSSA 9409 | 7:58 AM Venezia Mestre Ospedale | 2h41 | 10:39 AM Florence Santa Maria Novella | 1 transfer | |
Regionale 16874+ FRECCIAROSSA 9411 | 8:58 AM Venezia Mestre Ospedale | 2h41 | 11:39 AM Florence Santa Maria Novella | 1 transfer | |
Regionale 16680+ FRECCIAROSSA 9413 | 9:58 AM Venezia Mestre Ospedale | 2h41 | 12:39 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 16232+ FRECCIAROSSA 8419 | 11:58 AM Venezia Mestre Ospedale | 2h41 | 2:39 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 16775+ Intercity 584+ Regionale Veloce 4042 | 12:26 PM Venezia Mestre Ospedale | 4h07 | 4:33 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 16779+ FRECCIAROSSA 9421 | 12:58 PM Venezia Mestre Ospedale | 2h41 | 3:39 PM Florence Santa Maria Novella | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mestre to Florence Santa Maria Novella by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Mestre to Florence Santa Maria Novella trains with Omio?
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Regionale or Intercity to find the best option for your trip from Mestre to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are bus and train to ensure you get the best deal for traveling from Mestre to Florence Santa Maria Novella.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Mestre to Florence Santa Maria Novella.
Journey information
Overview: Train from Mestre to Florence Santa Maria Novella
Trains from Mestre to Florence Santa Maria Novella run on average 17 times per day, taking around 2h 42m. Cheap train tickets for this journey start at $19 (€15) but you can travel from only $8 (€6) by bus.
There are 2 trains per day. The earliest train runs at 04:20, the last at 17:58. The fastest train covers the 128 miles (206 km) distance in 2h 1m.
Distance 128 miles (206 km) |
Average train duration 2h 42m |
Cheapest ticket price $19 (€15) |
Trains per day 17 |
Direct trains 2 |
Fastest train 2h 1m |
First train 4:20 AM |
Last train 5:58 PM |
Cheapest Month Apr |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Train companies: Frecciarossa, Italo, Regionale, Intercity from Mestre to Florence Santa Maria Novella trainsFrecciarossa, Italo, Regionale, Intercity trains will get you between Mestre and Florence Santa Maria Novella from $8 (€6). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Regionale
Intercity
FAQs: Trains from Mestre to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Mestre to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mestre to Florence Santa Maria Novella
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available near the station, open 24/7.
- Outside the main entrance.
- €1
- Hotel Villa Sara
- Hotel Altieri
- Hotel Ducale
- Located near the main entrance
- The station has a simple layout with two platforms and a small waiting area.
- Bus: Several ACTV lines available
- Tram: Line T1
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Mestre
More options for your journey from Mestre to Florence Santa Maria Novella
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