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The cheapest and fastest trains from Mainz Hbf to Milan Centrale
Showing times and prices for Feb 27
Cheapest price
$245
Average price
$245
Fastest journey
8 h 28 m
Average duration
8 h 28 m
Trains per day
1
Distance
507 km
Cheap tickets
The best way to find a cheap train ticket from Mainz Hbf to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mainz Hbf to Milan Centrale will cost around $245 if you buy it on the day, but the cheapest tickets can be found for only $245.
Fast trains
It's difficult to get from Mainz Hbf to Milan Centrale without transferring at least once.
S5 · ECE 15107:22AM8h28
Mainz Hbf03:50PMMilan Centrale
$2451One-way
1 transfer
S5 · ECE 15107:22AM8h28
Mainz Hbf03:50PMMilan Centrale
$2451One-way
1 transfer
Travel Information
Compare bus, train, and flight for Mainz Hbf to Milan Centrale
Omio recommends booking the train as it is the most popular option from Mainz Hbf to Milan Centrale among Omio's users. If you are prioritising price take the flight with prices starting from $25. For those with little time consider booking a flight which can get you there in 1h 20m. The ticket price range depends on the travel mode: a flight costs an average of $25, and a train costs an average of $253.
Distance: 315 miles (507 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$288 Average price | $64 Average price Cheapest | $69 Average price |
7h 59m Average total duration 7h 29m Onboard + 30m Additional time* | 4h 20m Average total duration Fastest 1h 20m Onboard + 3h 0m Additional time* | 14h 15m Average total duration 13h 45m Onboard + 30m Additional time* |
Most popular train company |  Most popular airline |  Most popular bus company |
Direct Options | Direct Options | Direct Options |
Live departures
Mainz Hbf to Milan Centrale train times
The table below shows live departures for Mainz Hbf to Milan Centrale trains for tomorrow, Friday, February 27. You can also manually refresh the results below to see updated train journeys.
Last updated at 11:44 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| S5 · ECE 151 | On time 6:22 AM Mainz Hbf | 8h28 | 2:50 PM Milan Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mainz Hbf to Milan Centrale by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Fri
Feb 27
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Feb 28
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Why should you book Mainz Hbf to Milan Centrale trains with Omio?
Deutsche Bahn as well as Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and more offer trains services from Mainz Hbf to Milan Centrale.
Omio is an official ticket reseller for all your travel options from Mainz Hbf to Milan Centrale.
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC) or Deutsche Bahn Regio (DB Regional) to find the best option for your trip from Mainz Hbf to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mainz Hbf to Milan Centrale.
Why book with Omio over Trainline or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC) or Deutsche Bahn Regio (DB Regional) to find the best option for your trip from Mainz Hbf to Milan Centrale.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mainz Hbf to Milan Centrale.
Journey information
Overview: Train from Mainz Hbf to Milan Centrale
Germany
Italy
Trains from Mainz Hbf to Milan Centrale run on average 1 times per day, taking around 7h 29m. Cheap train tickets for this journey start at $253 (€201) but you can travel from only $25 (€20) by flight.
The earliest train runs at 00:08, the last at 20:42. The fastest train covers the 315 miles (507 km) distance in 7h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $25 (€20)
Distance 315 miles (507 km) |
Average train duration 7h 29m |
Cheapest ticket price $253 (€201) |
Trains per day 1 |
Fastest train 7h 35m |
First train 00:08 |
Last train 20:42 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $25 (€20)
Train companies: Deutsche Bahn, Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) from Mainz Hbf to Milan Centrale trainsDeutsche Bahn, Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) trains will get you between Mainz Hbf and Milan Centrale from $25 (€20). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
8h 10m
Cheapest Price
$297 (€236)
Deutsche Bahn frequency
1 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone
Trenitalia
About
Trenitalia is not only Italy's national railroad company but also the country's largest train operator. Trenitalia’s fleet of trains ncludes the high-speed Frecciarossa, Frecciargento and Frecciabianca trains as well as intercity, regional and night trains. Bathrooms and WiFi access are standard on long-distance routes. In most cases, the trains also provide barrier-free access. Trenitalia offers different tickets, which vary in price and flexibility: Base, Economy, Super Economy and Ordinaria. You can even use Trenitalia discount cards on Omio. Make sure to look out for the latest offers from Trenitalia on Omio to score special deals!
Luggage & cancellation policy
Luggage included
2 pieces of hand luggage per passenger included in ticket price
Luggage storage
Overhead racks, luggage areas at end of carriages, and spaces between seat backs
Cancellation Policy
Cancellation policies vary by ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car on high-speed trains, trolley service with snacks and beverages, vending machines on some trains
Seat reservation
Optional seat reservation, costs extra except on high-speed trains where it's mandatory and included
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available with advance notice
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, guide dogs travel free
Quiet zone
Süwex
Luggage & cancellation policy
Average Duration
8h 0m
Cheapest Price
$254 (€202)
Süwex frequency
5 a day
Deutsche Bahn Intercity (DB IC)
Luggage & cancellation policy
Average Duration
7h 35m
Cheapest Price
$293 (€233)
Deutsche Bahn Intercity (DB IC) frequency
6 a day
Deutsche Bahn Regio (DB Regional)
Luggage & cancellation policy
Average Duration
8h 15m
Cheapest Price
$253 (€201)
Deutsche Bahn Regio (DB Regional) frequency
7 a day
Nederlandse Spoorwegen (NS)
Luggage & cancellation policy
Average Duration
10h 34m
Nederlandse Spoorwegen (NS) frequency
1 a day
FAQs: Trains from Mainz Hbf to Milan Centrale
Find answers to the most common questions about traveling from Mainz Hbf to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.
Train ticket prices from Mainz Hbf to Milan Centrale can vary. The cheapest ticket starts at $253 (€201), while the average price is around $288 (€229).
The train from Mainz Hbf to Milan Centrale runs once a day and takes approximately 7h 35m.
The distance by train from Mainz Hbf to Milan Centrale is 315 miles (507 km).
The first train from Mainz Hbf to Milan Centrale leaves at 12:08 AM.
The last train from Mainz Hbf to Milan Centrale leaves at 8:42 PM.
There is no direct train service currently available from Mainz Hbf to Milan Centrale.
Unfortunately, there is no night train available from Mainz Hbf to Milan Centrale.
The cheapest way to get from Mainz Hbf to Milan Centrale is by flight, with a cost of around $25 (€20).
The train journey from Mainz Hbf to Milano Centrale is scenic, offering views of the Rhine Valley, rolling vineyards, and picturesque Swiss landscapes, including the Alps, providing a visually appealing travel experience.
A day trip from Mainz Hbf to Milano Centrale is not feasible, as the journey takes 7h 35m and trains operate 1 time per day over a distance of 315 miles (507 km).
Yes, you can take the train from Mainz Hbf to Milan Centrale.
popular train stations
Popular train stations from Mainz Hbf to Milan Centrale
Mainz
Milan
The major train station for departures in Mainz is Mainz Hbf. Find all the information you need to know about services, amenities and connections at Mainz Hbf for your trip from Mainz to Milan.
Amenities at train station
Wifi
Lockers
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Lounge
Lost and Found Office
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
Distance to city center
2 kmDining
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
Hotel
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
The major train station for arrivals in Milan is Milano Centrale. Find all the information you need to know about services, amenities and connections at Milano Centrale for your journey to Milan from Mainz.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 05:50 - 22:20
Distance to city center
2 kmWifi
- Free WiFi in the station.
Lockers
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Dining
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
Accessibility
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Hotel
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
Ticket Office
- Mon - Sun: 05:50 - 22:20
Information Desk
- Located next to the ticket office on the ground floor in the shopping gallery.
Public transit options for Milano Centrale
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Mainz Hbf
More options for your journey from Mainz Hbf to Milan Centrale
Here are some other resources that might have the information you need
Most popular trains to and from Milan Centrale and Mainz Hbf
Most popular train connections to Milan Centrale
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