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4.9
4.6The cheapest and fastest trains from Mainz Hbf to Milan Centrale
Cheapest price
$328
Average price
$328
Fastest journey
11 h 55 m
Average duration
12 h 55 m
Trains per day
3
Distance
507 km
The best way to find a cheap train ticket from Mainz Hbf to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mainz Hbf to Milan Centrale will cost around $328 if you buy it on the day, but the cheapest tickets can be found for only $328.
It's difficult to get from Mainz Hbf to Milan Centrale without transferring at least 2 times.
ICE 991 · RJ 83+
Regionale TRENORD 26385:40 AM12h55Mainz Hbf6:35 PMMilan Centrale$3281One-way2 transfers- ICE 991 · RJ 83+Regionale TRENORD 26365:40 AM11h55Mainz Hbf5:35 PMMilan Centrale$3281One-way2 transfers
- ICE 991 · RJ 83+Regionale TRENORD 26405:40 AM13h55Mainz Hbf7:35 PMMilan Centrale$3281One-way2 transfers
- ICE 991 · RJ 83+Regionale TRENORD 26365:40 AM11h55Mainz Hbf5:35 PMMilan Centrale$3281One-way2 transfers
- ICE 991 · RJ 83+Regionale TRENORD 26385:40 AM12h55Mainz Hbf6:35 PMMilan Centrale$3281One-way2 transfers
- ICE 991 · RJ 83+Regionale TRENORD 26405:40 AM13h55Mainz Hbf7:35 PMMilan Centrale$3281One-way2 transfers
Travel Information
Compare bus, train, and flight for Mainz Hbf to Milan Centrale
Omio recommends booking the train as it is the most popular option from Mainz Hbf to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $45. For those with little time consider booking a flight which can get you there in 1h 20m. The ticket price range depends on the travel mode: a bus costs an average of $45, and a train costs an average of $161.
Distance: 315 miles (507 km)
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$201 Average price | $187 Average price | $70 Average price Cheapest | $133 Average price (fuel + tolls) |
7h 59m Average total duration 7h 29m Onboard + 30m Additional time* | 4h 20m Average total duration Fastest 1h 20m Onboard + 3h 0m Additional time* | 14h 15m Average total duration 13h 45m Onboard + 30m Additional time* | 6h 52m Average total duration (door-to-door) |
Most popular train company |  Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Mainz Hbf to Milan Centrale:
A bus is $117 (€94) less than a flight for this route with tickets for a flight from Mainz Hbf to Milan Centrale costing on average $187 (€151).
A bus is $131 (€106) less than a train for this route with tickets for a train from Mainz Hbf to Milan Centrale costing on average $201 (€162).
Other travel options to Milan Centrale take longer:
Train takes on average 7h 29m.
Bus takes on average 13h 45m.
Tickets start at around $201 (€162) compared to roughly $133 (€108) in fuel and tolls — a saving of about $-67.84 (€-54.79). The journey takes 7h 29m versus 6h 52m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Mainz Hbf to Milan Centrale train times
The table below shows live departures for Mainz Hbf to Milan Centrale trains for tomorrow, Friday, May 29. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| ICE 991 · RJ 83+Regionale TRENORD 2638 | On time 5:40 AM Mainz Hbf | 12h55 | 6:35 PM Milan Centrale | 2 transfers | |
| ICE 991 · RJ 83+Regionale TRENORD 2636 | On time 5:40 AM Mainz Hbf | 11h55 | 5:35 PM Milan Centrale | 2 transfers | |
| ICE 991 · RJ 83+Regionale TRENORD 2640 | On time 5:40 AM Mainz Hbf | 13h55 | 7:35 PM Milan Centrale | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mainz Hbf to Milan Centrale by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 29
May 30
May 31
Jun 01
Jun 02
Jun 03
Jun 04
Why should you book Mainz Hbf to Milan Centrale trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC) or Deutsche Bahn Regio (DB Regional) to find the best option for your trip from Mainz Hbf to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mainz Hbf to Milan Centrale.
Why book with Omio over Trainline or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC) or Deutsche Bahn Regio (DB Regional) to find the best option for your trip from Mainz Hbf to Milan Centrale.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mainz Hbf to Milan Centrale.
Journey information
Overview: Train from Mainz Hbf to Milan Centrale
Germany
Italy
Trains from Mainz Hbf to Milan Centrale run on average 1 times per day, taking around 7h 29m. Cheap train tickets for this journey start at $161 (€130) but you can travel from only $25 (€20) by flight.
The earliest train runs at 06:22, the last at 06:22. The fastest train covers the 315 miles (507 km) distance in 8h 28m.
Distance 315 miles (507 km) |
Average train duration 7h 29m |
Cheapest ticket price $161 (€130) |
Trains per day 1 |
Fastest train 8h 28m |
First train 6:22 AM |
Last train 6:22 AM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Oct - Dec |
Train companies: Deutsche Bahn, Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) from Mainz Hbf to Milan Centrale trainsDeutsche Bahn, Trenitalia, Süwex, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) trains will get you between Mainz Hbf and Milan Centrale from $25 (€20). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Trenitalia
Süwex
Deutsche Bahn Intercity (DB IC)
Deutsche Bahn Regio (DB Regional)
Nederlandse Spoorwegen (NS)
FAQs: Trains from Mainz Hbf to Milan Centrale
Find answers to the most common questions about traveling from Mainz Hbf to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.
popular train stations
Popular train stations from Mainz Hbf to Milan Centrale
Wifi
Lockers
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Lounge
Lost and Found Office
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Desk
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Mainz Hbf
More options for your journey from Mainz Hbf to Milan Centrale
Here are some other resources that might have the information you need
Most popular trains to and from Milan Centrale and Mainz Hbf
Most popular train connections to Milan Centrale
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