The cheapest and fastest trains from Lyon Part Dieu to Brussels-Midi
Cheapest price
$125
Average price
$253
Fastest journey
3 h 54 m
Average duration
3 h 58 m
Trains per day
18
Distance
566 km
The best way to find a cheap train ticket from Lyon Part Dieu to Brussels-Midi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon Part Dieu to Brussels-Midi will cost around $253 if you buy it on the day, but the cheapest tickets can be found for only $125.
Of the 18 trains that leave Lyon Part Dieu for Brussels-Midi on Fri, May 08, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 08 the direct trains cover the 566 km distance in an average of 3 h 58 m but if you time it right, some trains will get you there in just 3 h 54 m .
On Fri, May 08 the slowest trains will take 4 h 6 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
98827:00 PM3h56Lyon Part Dieu10:56 PMBrussels-Midi$1251One-way0 transfers
6628+
93936:04 PM4h43Lyon Part Dieu10:47 PMBrussels-Midi$1581One-way1 transfer
98685:00 PM3h56Lyon Part Dieu8:56 PMBrussels-Midi$1691One-way0 transfers
98525:49 AM3h54Lyon Part Dieu9:43 AMBrussels-Midi$1931One-way0 transfers
6622+
93713:04 PM4h13Lyon Part Dieu7:17 PMBrussels-Midi$2071One-way1 transfer
98525:49 AM3h54Lyon Part Dieu9:43 AMBrussels-Midi$1931One-way0 transfers
98645:00 PM3h56Lyon Part Dieu8:56 PMBrussels-Midi$2331One-way0 transfers
98685:00 PM3h56Lyon Part Dieu8:56 PMBrussels-Midi$1691One-way0 transfers
98827:00 PM3h56Lyon Part Dieu10:56 PMBrussels-Midi$1251One-way0 transfers
6696+
93875:38 PM4h06Lyon Part Dieu9:44 PMBrussels-Midi$2181One-way1 transfer
Travel Information
Compare train, bus, and flight for Lyon Part Dieu to Brussels-Midi
Omio recommends booking the train as it is the most popular option from Lyon Part Dieu to Brussels-Midi among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 46m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $68.
Distance: 351 miles (566 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$123 Average price | $45 Average price Cheapest | $242 Average price | $200 Average price (fuel + tolls) |
4h 15m Average total duration 3h 45m Onboard + 30m Additional time* | 10h 2m Average total duration 9h 32m Onboard + 30m Additional time* | 4h 46m Average total duration Fastest 1h 46m Onboard + 3h 0m Additional time* | 6h 45m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon Part Dieu to Brussels-Midi:
A bus is $78 (€62) less than a train for this route with tickets for a train from Lyon Part Dieu to Brussels-Midi costing on average $123 (€98).
A bus is $197 (€157) less than a flight for this route with tickets for a flight from Lyon Part Dieu to Brussels-Midi costing on average $242 (€193).
Other travel options to Brussels-Midi take longer:
Train takes on average 3h 45m.
Bus takes on average 9h 32m.
The journey is about 3h 0m faster (3h 45m by train vs 6h 45m by car) and roughly $77 (€62) cheaper once you factor in fuel and tolls ($123 (€98) vs $200 (€160)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with TGV, SNCF | TGV INOUI.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Live departures
Lyon Part Dieu to Brussels-Midi train times
The table below shows live departures for Lyon Part Dieu to Brussels-Midi trains for today, Thursday, May 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
6628+ 9393 | 6:04 PM Lyon Part Dieu | 4h43 | 10:47 PM Brussels-Midi | 1 transfer | |
| Friday, May 8 | |||||
6690+ 9423 | 7:04 AM Lyon Part Dieu | 4h13 | 11:17 AM Brussels-Midi | 1 transfer | |
6608+ 9429 | 8:04 AM Lyon Part Dieu | 4h13 | 12:17 PM Brussels-Midi | 1 transfer | |
6608+ 9329 | 8:04 AM Lyon Part Dieu | 4h13 | 12:17 PM Brussels-Midi | 1 transfer | |
6612+ 9341 | 10:04 AM Lyon Part Dieu | 4h13 | 2:17 PM Brussels-Midi | 1 transfer | |
6614+ 9351 | 11:04 AM Lyon Part Dieu | 4h44 | 3:48 PM Brussels-Midi | 1 transfer | |
6616+ 9357 | 12:00 PM Lyon Part Dieu | 4h44 | 4:44 PM Brussels-Midi | 1 transfer | |
6694+ 9359 | 1:04 PM Lyon Part Dieu | 4h13 | 5:17 PM Brussels-Midi | 1 transfer | |
6694+ 9459 | 1:04 PM Lyon Part Dieu | 4h13 | 5:17 PM Brussels-Midi | 1 transfer | |
6620+ 9365 | 2:04 PM Lyon Part Dieu | 4h13 | 6:17 PM Brussels-Midi | 1 transfer | |
6622+ 9471 | 3:04 PM Lyon Part Dieu | 4h13 | 7:17 PM Brussels-Midi | 1 transfer | |
6622+ 9371 | 3:04 PM Lyon Part Dieu | 4h13 | 7:17 PM Brussels-Midi | 1 transfer | |
6624+ 9381 | 4:04 PM Lyon Part Dieu | 4h43 | 8:47 PM Brussels-Midi | 1 transfer | |
9868 | 5:00 PM Lyon Part Dieu | 3h56 | 8:56 PM Brussels-Midi | 0 transfersDirect | |
9864 | 5:00 PM Lyon Part Dieu | 3h56 | 8:56 PM Brussels-Midi | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Lyon Part Dieu to Brussels-Midi by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 08
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Why should you book Lyon Part Dieu to Brussels-Midi trains with Omio?
Why book with Omio vs TGV?
- Compare with other providers: On Omio, you can not only buy tickets for TGV, but also compare tickets for the likes of SNCF | TGV INOUI or Frecciarossa to find the best option for your trip from Lyon Part Dieu to Brussels-Midi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare TGV with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon Part Dieu to Brussels-Midi.
Journey information
Overview: Train from Lyon Part Dieu to Brussels-Midi
Trains from Lyon Part Dieu to Brussels-Midi run on average 4 times per day, taking around 3h 45m. Cheap train tickets for this journey start at $59 (€47) but you can travel from only $24 (€19) by bus.
There are 3 trains per day. The earliest train runs at 04:48, the last at 18:00. The fastest train covers the 351 miles (566 km) distance in 3h 43m.
Distance 351 miles (566 km) |
Average train duration 3h 45m |
Cheapest ticket price $59 (€47) |
Trains per day 4 |
Direct trains 3 |
Fastest train 3h 43m |
First train 4:48 AM |
Last train 6:00 PM |
Cheapest Month Apr |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Sun |
Train companies: TGV, SNCF | TGV INOUI, Frecciarossa from Lyon Part Dieu to Brussels-Midi trainsTGV, SNCF | TGV INOUI, Frecciarossa trains will get you between Lyon Part Dieu and Brussels-Midi from $24 (€19). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
SNCF | TGV INOUI
Frecciarossa
FAQs: Trains from Lyon Part Dieu to Brussels-Midi
Find answers to the most common questions about traveling from Lyon Part Dieu to Brussels-Midi by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels-Midi, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Lyon Part Dieu to Brussels-Midi
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Free unlimited WiFi.
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
- Complimentary personalized care is available.
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Located in the station's main hall.
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
More options for your journey from Lyon Part Dieu to Brussels-Midi
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