The cheapest and fastest trains from Lyon Part Dieu to Florence Santa Maria Novella
Cheapest price
$163
Average price
$163
Fastest journey
7 h 20 m
Average duration
7 h 20 m
Trains per day
1
Distance
550 km
The best way to find a cheap train ticket from Lyon Part Dieu to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon Part Dieu to Florence Santa Maria Novella will cost around $163 if you buy it on the day, but the cheapest tickets can be found for only $163.
Of the 1 trains that leave Lyon Part Dieu for Florence Santa Maria Novella on Wed, Nov 26, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 26 the direct trains cover the 550 km distance in an average of 7 h 20 m but if you time it right, some trains will get you there in just 7 h 20 m .
On Wed, Nov 26 the slowest trains will take 7 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for Lyon Part Dieu to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Lyon Part Dieu to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a flight which can get you there in 1h 21m. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €29.
Distance: 341 miles (550 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€111 Average price | €37 Average price Cheapest | €130 Average price |
7h 25m Average total duration 6h 55m Onboard + 30m Additional time* | 10h 31m Average total duration 10h 1m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 1h 21m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Lyon Part Dieu to Florence Santa Maria Novella train times
The table below shows live departures for Lyon Part Dieu to Florence Santa Maria Novella trains for today, Tuesday, November 25. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FRECCIAROSSA 1000 9281+ 9947 | On time 8:30 AM Lyon Part Dieu | 8h05 | 4:35 PM Florence Santa Maria Novella | 1 transfer | |
FRECCIAROSSA 1000 9281+ 9951 | 8:30 AM Lyon Part Dieu | 9h05 | 5:35 PM Florence Santa Maria Novella | 1 transfer | |
FRECCIAROSSA 1000 9281+ 8143 | 8:30 AM Lyon Part Dieu | 7h05 | 3:35 PM Florence Santa Maria Novella | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon Part Dieu to Florence Santa Maria Novella by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 26
Nov 27
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Why should you book Lyon Part Dieu to Florence Santa Maria Novella trains with Omio?
Trenitalia as well as SNCF offer trains services from Lyon Part Dieu to Florence Santa Maria Novella. Omio is an official ticket reseller for all your travel options from Lyon Part Dieu to Florence Santa Maria Novella.
Why book with Omio vs Trenitalia?
- Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of SNCF to find the best option for your trip from Lyon Part Dieu to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon Part Dieu to Florence Santa Maria Novella.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Trenitalia tickets can be bought on Trenitalia's website or third party sellers, Omio allows you to compare with the likes of SNCF to help you choose the right option for your journey from Lyon Part Dieu to Florence Santa Maria Novella.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon Part Dieu to Florence Santa Maria Novella.
Journey information
Overview: Train from Lyon Part Dieu to Florence Santa Maria Novella
Trains from Lyon Part Dieu to Florence Santa Maria Novella run on average 1 times per day, taking around 6h 55m. Cheap train tickets for this journey start at $75 (€61) but you can travel from only $24 (€19) by bus.
The earliest train runs at 07:30, the last at 07:30. The fastest train covers the 341 miles (550 km) distance in 7h 20m.
Distance 341 miles (550 km) |
Average train duration 6h 55m |
Cheapest ticket price $75 (€61) |
Trains per day 1 |
Fastest train 7h 20m |
First train 07:30 |
Last train 07:30 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Lyon Part Dieu to Florence Santa Maria Novella start from as low as $75 (€61) if booked well in advance.
- Standard Fares: Typically, trains cost $137 (€111) depending on the train type and class.
Journey Duration & Frequency
- On average there are 1 daily trains from Lyon Part Dieu to Florence Santa Maria Novella with 0 direct service.
- The fastest trains can take as little as 7h 20m but the average duration is 6h 55m
Train Operators
- Travel from Lyon Part Dieu to Florence Santa Maria Novella with Trenitalia and SNCF
- The most booked train company for this route on Omio is Trenitalia.
Stations & Schedule
- First train typically departs at 07:30 AM and the last at 07:30 AM
Train companies: Trenitalia, SNCF from Lyon Part Dieu to Florence Santa Maria Novella trainsTrenitalia, SNCF trains will get you between Lyon Part Dieu and Florence Santa Maria Novella from $24 (€19). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
SNCF
FAQs: Trains from Lyon Part Dieu to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Lyon Part Dieu to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Lyon Part Dieu to Florence Santa Maria Novella
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Free unlimited WiFi.
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
- Complimentary personalized care is available.
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Located in the station's main hall.
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
More options for your journey from Lyon Part Dieu to Florence Santa Maria Novella
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