The cheapest and fastest trains from Lyon Part Dieu to Florence Santa Maria Novella
Cheapest price
$119
Average price
$164
Fastest journey
8 h 4 m
Average duration
8 h 59 m
Trains per day
20
Distance
550 km
The best way to find a cheap train ticket from Lyon Part Dieu to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon Part Dieu to Florence Santa Maria Novella will cost around $164 if you buy it on the day, but the cheapest tickets can be found for only $119.
It's difficult to get from Lyon Part Dieu to Florence Santa Maria Novella without transferring at least once.
9243+
S5 TRENORD 11857 · Regionale Veloce TTPER 2475 · Regionale 178517:50 AM14h20Lyon Part Dieu10:10 PMFlorence Santa Maria Novella$1191One-way4 transfers
9243+
Regionale 2295 · Regionale Veloce TTPER 3939 · Regionale 178517:50 AM14h20Lyon Part Dieu10:10 PMFlorence Santa Maria Novella$1191One-way4 transfers
9243+
Regionale 2295 · Regionale 18539+
185037:50 AM16h00Lyon Part Dieu11:50 PMFlorence Santa Maria Novella$1251One-way3 transfers
9243+
Regionale 2295 · Regionale Veloce TTPER 3939 · Regionale 178518:08 AM14h02Lyon Part Dieu10:10 PMFlorence Santa Maria Novella$1261One-way5 transfers
9243+
S5 TRENORD 11857 · Regionale Veloce TTPER 2475 · Regionale 178518:08 AM14h02Lyon Part Dieu10:10 PMFlorence Santa Maria Novella$1261One-way5 transfers
FRECCIAROSSA 1000 9281+
99479:31 AM8h04Lyon Part Dieu5:35 PMFlorence Santa Maria Novella$2241One-way1 transfer
FRECCIAROSSA 1000 9281+
99479:31 AM8h04Lyon Part Dieu5:35 PMFlorence Santa Maria Novella$1491One-way1 transfer
FRECCIAROSSA 1000 9281+
99519:31 AM9h04Lyon Part Dieu6:35 PMFlorence Santa Maria Novella$2241One-way1 transfer
9243+
FRECCIAROSSA 9323+
17516 · 179728:08 AM9h42Lyon Part Dieu5:50 PMFlorence Santa Maria Novella$1721One-way3 transfers
9243+
FRECCIAROSSA 9323+
185037:50 AM10h00Lyon Part Dieu5:50 PMFlorence Santa Maria Novella$1661One-way2 transfers
Travel Information
Compare train, bus, and flight for Lyon Part Dieu to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Lyon Part Dieu to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the train with prices starting from $31. For those with little time consider booking a flight which can get you there in 3h 9m. The ticket price range depends on the travel mode: a train costs an average of $31, and a flight costs an average of $36.
Distance: 341 miles (550 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$75 Average price Cheapest | $81 Average price | $521 Average price | $314 Average price (fuel + tolls) |
7h 31m Average total duration 7h 1m Onboard + 30m Additional time* | 11h 46m Average total duration 11h 16m Onboard + 30m Additional time* | 6h 9m Average total duration Fastest 3h 9m Onboard + 3h 0m Additional time* | 7h 10m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon Part Dieu to Florence Santa Maria Novella:
A train is $6 (€5) less than a bus for this route with tickets for a bus from Lyon Part Dieu to Florence Santa Maria Novella costing on average $81 (€65).
A train is $446 (€359) less than a flight for this route with tickets for a flight from Lyon Part Dieu to Florence Santa Maria Novella costing on average $521 (€419).
Other travel options to Florence Santa Maria Novella take longer:
Train takes on average 7h 1m.
Bus takes on average 11h 16m.
The journey is about 9m faster (7h 1m by train vs 7h 10m by car) and roughly $239 (€192) cheaper once you factor in fuel and tolls ($75 (€60) vs $314 (€252)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Live departures
Lyon Part Dieu to Florence Santa Maria Novella train times
The table below shows live departures for Lyon Part Dieu to Florence Santa Maria Novella trains for today, Tuesday, August 25. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FRECCIAROSSA 1000 9281+ 9947 | 9:31 AM Lyon Part Dieu | 8h04 | 5:35 PM Florence Santa Maria Novella | 1 transfer | |
FRECCIAROSSA 1000 9281+ 9947 | 9:31 AM Lyon Part Dieu | 8h04 | 5:35 PM Florence Santa Maria Novella | 1 transfer | |
FRECCIAROSSA 1000 9281+ 9951 | 9:31 AM Lyon Part Dieu | 9h04 | 6:35 PM Florence Santa Maria Novella | 1 transfer | |
FRECCIAROSSA 1000 9281+ 9955 | 9:31 AM Lyon Part Dieu | 10h04 | 7:35 PM Florence Santa Maria Novella | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon Part Dieu to Florence Santa Maria Novella by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 26
Aug 27
Aug 28
Aug 29
Aug 30
Aug 31
Sep 01
Why should you book Lyon Part Dieu to Florence Santa Maria Novella trains with Omio?
Why book with Omio vs Trenitalia?
- Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of SNCF | TGV INOUI or Regionale to find the best option for your trip from Lyon Part Dieu to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon Part Dieu to Florence Santa Maria Novella.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon Part Dieu to Florence Santa Maria Novella.
Journey information
Overview: Train from Lyon Part Dieu to Florence Santa Maria Novella
Trains from Lyon Part Dieu to Florence Santa Maria Novella run on average 3 times per day, taking around 7h 1m. Cheap train tickets for this journey start at $31 (€25) but you can travel from only $19 (€15) by bus.
The earliest train runs at 07:31, the last at 07:31. The fastest train covers the 341 miles (550 km) distance in 6h 21m.
Distance 341 miles (550 km) |
Average train duration 7h 1m |
Cheapest ticket price $31 (€25) |
Trains per day 3 |
Fastest train 6h 21m |
First train 7:31 AM |
Last train 7:31 AM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Thu |
Train companies: Trenitalia, SNCF | TGV INOUI, Regionale from Lyon Part Dieu to Florence Santa Maria Novella trainsTrenitalia, SNCF | TGV INOUI, Regionale trains will get you between Lyon Part Dieu and Florence Santa Maria Novella from $19 (€15). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
SNCF | TGV INOUI
Regionale
FAQs: Trains from Lyon Part Dieu to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Lyon Part Dieu to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Lyon Part Dieu to Florence Santa Maria Novella
Most Lyon Part Dieu to Florence Santa Maria Novella trains use the Lyon Part Dieu to Firenze Santa Maria Novella station pair. Use this guide to compare Lyon Part Dieu and Florence Santa Maria Novella train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Lyon Part Dieu from Lyon city centre
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu train station facilities and services
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Wi-Fi and ATMs
Free unlimited WiFi. ATMs are located in the station's main hall.
Tickets and information
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage and lost property
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Parking, taxis and toilets
Available at Lyon Part Dieu: Parking, Taxis, WC.
Bike and car services
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Shops, hotels and contact
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
Getting to Firenze Santa Maria Novella from Florence city centre
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella train station facilities and services
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Wi-Fi and ATMs
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
Tickets and information
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Parking, taxis and toilets
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Bike and car services
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
More options for your journey from Lyon Part Dieu to Florence Santa Maria Novella
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