Lyon Part Dieu to Florence Santa Maria Novella train with Trenitalia

Wed, May 27
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Trenitalia
SNCF | TGV INOUI
Regionale
Deutsche Bahn
iryo
2,000+ travel companies
Trenitalia
SNCF | TGV INOUI
Regionale
Deutsche Bahn
iryo
2,000+ travel companies
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The cheapest and fastest trains from Lyon Part Dieu to Florence Santa Maria Novella

Showing times and prices for May 27

Cheapest price

$103

Average price

$103

Fastest journey

20 h 52 m

Average duration

20 h 52 m

Trains per day

1

Distance

550 km

Cheap tickets

The best way to find a cheap train ticket from Lyon Part Dieu to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Lyon Part Dieu to Florence Santa Maria Novella will cost around $103 if you buy it on the day, but the cheapest tickets can be found for only $103.

Fast trains

It's difficult to get from Lyon Part Dieu to Florence Santa Maria Novella without transferring at least once.

  • Trenitalia
    5:23 PM20h52
    Lyon Part Dieu
    2:15 PMFlorence Santa Maria Novella
    $1031One-way
    1 transfer

Travel Information

Compare train, bus, and flight for Lyon Part Dieu to Florence Santa Maria Novella

Omio recommends booking the train as it is the most popular option from Lyon Part Dieu to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from $20. For those with little time consider booking a flight which can get you there in 1h 21m. The ticket price range depends on the travel mode: a bus costs an average of $20, and a train costs an average of $225.

Distance: 341 miles (550 km)

Compare train with

Most popular
Train
Bus
Flight
Driving

$225

Average price

$45

Average price

Cheapest

$197

Average price

$311

Average price

(fuel + tolls)

7h 47m

Average total duration

7h 17m

Onboard

+

30m

Additional time*

10h 57m

Average total duration

10h 27m

Onboard

+

30m

Additional time*

4h 21m

Average total duration

Fastest

1h 21m

Onboard

+

3h 0m

Additional time*

7h 10m

Average total duration

(door-to-door)

Trenitalia

Most popular train company

BlaBlaCar Bus

Most popular bus company

Volotea

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Lyon Part Dieu to Florence Santa Maria Novella is a bus with an average price of $45 (€36).

This is compared to other travel options from Lyon Part Dieu to Florence Santa Maria Novella:

A bus is $152 (€123) less than a flight for this route with tickets for a flight from Lyon Part Dieu to Florence Santa Maria Novella costing on average $197 (€159).

A bus is $180 (€145) less than a train for this route with tickets for a train from Lyon Part Dieu to Florence Santa Maria Novella costing on average $225 (€181).

The fastest way to travel from Lyon Part Dieu to Florence Santa Maria Novella is by flight with an average journey time of 1h 21m.

Other travel options to Florence Santa Maria Novella take longer:

Train takes on average 7h 17m.

Bus takes on average 10h 27m.

It's helpful to compare your options as there are 3 ways to travel between Lyon Part Dieu and Florence Santa Maria Novella including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Lyon Part Dieu to Florence Santa Maria Novella among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.

Tickets start at around $225 (€181) compared to roughly $311 (€251) in fuel and tolls — a saving of about $86 (€69). The journey takes 7h 17m versus 7h 10m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.

Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.

Live departures

Lyon Part Dieu to Florence Santa Maria Novella train times

The table below shows live departures for Lyon Part Dieu to Florence Santa Maria Novella trains for tomorrow, Wednesday, May 27. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Trenitalia5:23 PM Lyon Part Dieu
20h52
2:15 PM Florence Santa Maria Novella1 transfer

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Lyon Part Dieu to Florence Santa Maria Novella by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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May 27
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Why should you book Lyon Part Dieu to Florence Santa Maria Novella trains with Omio?

Trenitalia as well as SNCF | TGV INOUI or Regionale offer trains services from Lyon Part Dieu to Florence Santa Maria Novella.
Omio is an official ticket reseller for all your travel options from Lyon Part Dieu to Florence Santa Maria Novella.

Why book with Omio vs Trenitalia?

  • Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of SNCF | TGV INOUI or Regionale to find the best option for your trip from Lyon Part Dieu to Florence Santa Maria Novella.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon Part Dieu to Florence Santa Maria Novella.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon Part Dieu to Florence Santa Maria Novella.

Journey information

Overview: Train from Lyon Part Dieu to Florence Santa Maria Novella

FranceFrance
ItalyItaly
Icon of train

Trains from Lyon Part Dieu to Florence Santa Maria Novella run on average 1 times per day, taking around 7h 17m. Cheap train tickets for this journey start at $225 (€181) but you can travel from only $20 (€16) by bus.

The earliest train runs at 08:31, the last at 08:31. The fastest train covers the 341 miles (550 km) distance in 7h 19m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $20 (€16)
Distance
341 miles (550 km)
Average train duration
7h 17m
Cheapest ticket price
$225 (€181)
Trains per day
1
Fastest train
7h 19m
First train
8:31 AM
Last train
8:31 AM
Cheapest Month
Oct
Cheapest Day
Wed
High Season
Apr - Jun
Low Season
Oct - Dec
Busiest Day
Sun
Least Busy Day
Sun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $20 (€16)

Train companies: Trenitalia, SNCF | TGV INOUI, Regionale from Lyon Part Dieu to Florence Santa Maria Novella trainsTrenitalia, SNCF | TGV INOUI, Regionale trains will get you between Lyon Part Dieu and Florence Santa Maria Novella from $20 (€16). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Trenitalia

About
Trenitalia is not only Italy's national railroad company but also the country's largest train operator. Trenitalia’s fleet of trains ncludes the high-speed Frecciarossa, Frecciargento and Frecciabianca trains as well as intercity, regional and night trains. Bathrooms and WiFi access are standard on long-distance routes. In most cases, the trains also provide barrier-free access. Trenitalia offers different tickets, which vary in price and flexibility: Base, Economy, Super Economy and Ordinaria. You can even use Trenitalia discount cards on Omio. Make sure to look out for the latest offers from Trenitalia on Omio to score special deals!
Luggage & cancellation policy
Trenitalia frequency
1 a day
Luggage included
2 pieces of hand luggage per passenger included in ticket price
Luggage storage
Overhead racks, luggage areas at end of carriages, and spaces between seat backs
Cancellation Policy
Cancellation policies vary by ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car on high-speed trains, trolley service with snacks and beverages, vending machines on some trains
Seat reservation
Optional seat reservation, costs extra except on high-speed trains where it's mandatory and included
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available with advance notice
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, guide dogs travel free
Quiet zone

SNCF | TGV INOUI

About
SNCF's TGV INOUI is a premium high-speed train service operating across France and to other European cities. Launched in 2017, it aims to provide an enhanced travel experience with greater comfort, connectivity, and services compared to traditional TGV services. TGV INOUI trains offer features like adjustable seats, electrical outlets, fold-down tables, and dedicated luggage spaces. Passengers can enjoy onboard Wi-Fi and access to the TGV INOUI portal for entertainment and journey information. The service also includes a "Bistro TGV INOUI" for dining, with options for online ordering. SNCF is also introducing a new generation of TGV INOUI trains from 2026, which will be more modular, energy-efficient, and 97% recyclable.
Luggage & cancellation policy
Luggage included
1 hand luggage + 2 pieces of luggage free of charge
Luggage storage
Overhead racks, end of carriages, between seats
Cancellation Policy
Refund conditions depend on ticket type
Refund
Full refund if train canceled
Amenities on board the train
Wifi
Food sold onboard
Restaurant car (not all trains), at-seat service in 1st class, snack bar/cafe
Seat reservation
Second class: Optional, additional fee. First class: Included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, boarding assistance available
Pets
Small pets in carriers: Free. Large dogs: Paid ticket required. Guide dogs: Free
Quiet zone

Regionale

About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
20h 52m
Cheapest Price
$103 (€83)
Regionale frequency
1 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone

Complete guide to Firenze Santa Maria Novella

Things to do in Firenze Santa Maria Novella

Discover the best of Firenze Santa Maria Novella — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Firenze Santa Maria Novella trip today.

  • Must visit

Galleria degli Uffizi

World-famous Renaissance gallery with masterpieces by Botticelli, Leonardo, Michelangelo, and Caravaggio. One of Florence’s essential museum visits.

  • Must visit

Galleria dell'Accademia di Firenze

Best known for Michelangelo’s David, this museum also holds important Florentine paintings and sculptures. Timed-entry tickets are commonly used.

  • Recommended

Museo dell'Opera del Duomo

Outstanding museum preserving original works from the Florence Cathedral complex, including sculptures by Michelangelo, Donatello, and Ghiberti.

Euro

Moderate by Italian standards. Cafes and casual meals are reasonable, but hotels and central dining near the station cost more.

Average meal costs

Budget
EUR 8-15 for pizza, panini, or takeaway.
Mid-range
EUR 20-35 per person at a casual restaurant.
Fine dining
EUR 60+ per person at upscale restaurants.
Coffee
EUR 1.50-3 for espresso or cappuccino.

Tipping culture

Service is often included or covered by a coperto. Tipping is not required, but rounding up or leaving EUR 1-3 for good service is appreciated. Taxis are usually rounded up.

FAQs: Trains from Lyon Part Dieu to Florence Santa Maria Novella

Find answers to the most common questions about traveling from Lyon Part Dieu to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Lyon Part Dieu to Florence Santa Maria Novella can vary. The cheapest ticket starts at $225 (€181), while the average price is around $225 (€181).
The train from Lyon Part Dieu to Florence Santa Maria Novella runs once a day and takes approximately 7h 19m.
The first train from Lyon Part Dieu to Florence Santa Maria Novella leaves at 8:31 AM.
The distance by train from Lyon Part Dieu to Florence Santa Maria Novella is 341 miles (550 km).
The last train from Lyon Part Dieu to Florence Santa Maria Novella leaves at 8:31 AM.
There is no high speed train available from Lyon Part Dieu to Florence Santa Maria Novella.
There is no direct train service currently available from Lyon Part Dieu to Florence Santa Maria Novella.
Unfortunately, there is no night train available from Lyon Part Dieu to Florence Santa Maria Novella.
The cheapest way to get from Lyon Part Dieu to Florence Santa Maria Novella is by bus, with a cost of around $20 (€16).
The train journey from Lyon Part Dieu to Firenze Santa Maria Novella is quite scenic, offering views of the picturesque French countryside, the majestic Alps, and the rolling hills of Tuscany, making it a visually delightful experience.
A day trip from Lyon Part Dieu to Firenze Santa Maria Novella is not feasible as the journey takes 7h 19m and the distance is 341 miles (550 km). The frequency of trains is 1 per day.
Yes, you can take the train from Lyon Part Dieu to Florence Santa Maria Novella.
Since both Lyon Part Dieu and Florence Santa Maria Novella are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Florence Santa Maria Novella include Pisa, Bologna, Siena, Lucca, Verona.
We recommend using the train as it is the most popular way to get from Lyon Part Dieu to Florence Santa Maria Novella among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Lyon Part Dieu to Florence Santa Maria Novella

Lyon
Florence
The major train station for departures in Lyon is Lyon Part Dieu. Find all the information you need to know about services, amenities and connections at Lyon Part Dieu for your trip from Lyon to Florence.
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • Mon - Wed: 05:00 - 20:45
  • Thu - Sat: 05:00 - 21:45
  • Sun: 06:45 - 21:45
ticketOfficeHours
Distance to city center
1 km
Wifi
Wifi
  • Free unlimited WiFi.
Lockers
Lockers
  • Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
Dining
Dining
  • Alto Café
  • Paul
  • Paul The Café
  • Starbucks
  • Exki
  • Sushi Shop
  • Carrefour
Accessibility
Accessibility
  • Complimentary personalized care is available.
Hotel
Hotel
  • Radisson Blu Hotel Lyon
  • Mercure Lyon Center
  • ibis Styles Lyon Center
Ticket Office
Ticket Office
  • Mon - Wed: 05:00 - 20:45
  • Thu - Sat: 05:00 - 21:45
  • Sun: 06:45 - 21:45
Information Desk
Information Desk
  • Located in the station's main hall.
Public transit options for Lyon Part Dieu
  • Metro lines: A, B, C, D
  • Tram lines: T4, K240, T3, K100
  • Bus lines: 2960, C2, C3, C6, C9
  • Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE

More options for your journey from Lyon Part Dieu to Florence Santa Maria Novella

Here are some other resources that might have the information you need

Most popular trains to and from Florence Santa Maria Novella and Lyon Part Dieu

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