- Must visit
Galleria degli Uffizi
World-famous Renaissance gallery with masterpieces by Botticelli, Leonardo, Michelangelo, and Caravaggio. Timed entry is strongly recommended due to high demand.
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The cheapest and fastest trains from Lyon Part Dieu to Florence Santa Maria Novella
Showing times and prices for Jul 12
Cheapest price
$186
Average price
$333
Fastest journey
8 h 11 m
Average duration
9 h 23 m
Trains per day
5
Distance
550 km
Cheap tickets
The best way to find a cheap train ticket from Lyon Part Dieu to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon Part Dieu to Florence Santa Maria Novella will cost around $333 if you buy it on the day, but the cheapest tickets can be found for only $186.
Fast trains
It's difficult to get from Lyon Part Dieu to Florence Santa Maria Novella without transferring at least once.
FRECCIAROSSA 1000 9281+
99599:24 AM11h11Lyon Part Dieu8:35 PMFlorence Santa Maria Novella$1861One-way1 transfer- FRECCIAROSSA 1000 9281+99479:24 AM8h11Lyon Part Dieu5:35 PMFlorence Santa Maria Novella$2271One-way1 transfer
- FRECCIAROSSA 1000 9281+99479:24 AM8h11Lyon Part Dieu5:35 PMFlorence Santa Maria Novella$4171One-way1 transfer
- FRECCIAROSSA 1000 9281+99519:24 AM9h11Lyon Part Dieu6:35 PMFlorence Santa Maria Novella$4171One-way1 transfer
- FRECCIAROSSA 1000 9281+99559:24 AM10h11Lyon Part Dieu7:35 PMFlorence Santa Maria Novella$4171One-way1 transfer
- FRECCIAROSSA 1000 9281+99479:24 AM8h11Lyon Part Dieu5:35 PMFlorence Santa Maria Novella$4171One-way1 transfer
- FRECCIAROSSA 1000 9281+99479:24 AM8h11Lyon Part Dieu5:35 PMFlorence Santa Maria Novella$2271One-way1 transfer
- FRECCIAROSSA 1000 9281+99519:24 AM9h11Lyon Part Dieu6:35 PMFlorence Santa Maria Novella$4171One-way1 transfer
- FRECCIAROSSA 1000 9281+99559:24 AM10h11Lyon Part Dieu7:35 PMFlorence Santa Maria Novella$4171One-way1 transfer
- FRECCIAROSSA 1000 9281+99599:24 AM11h11Lyon Part Dieu8:35 PMFlorence Santa Maria Novella$1861One-way1 transfer
Travel Information
Compare train, bus, and flight for Lyon Part Dieu to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Lyon Part Dieu to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from $20. For those with little time consider booking a flight which can get you there in 1h 21m. The ticket price range depends on the travel mode: a bus costs an average of $20, and a train costs an average of $221.
Distance: 341 miles (550 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$221 Average price | $44 Average price Cheapest | $193 Average price | $305 Average price (fuel + tolls) |
7h 47m Average total duration 7h 17m Onboard + 30m Additional time* | 10h 57m Average total duration 10h 27m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 1h 21m Onboard + 3h 0m Additional time* | 7h 10m Average total duration (door-to-door) |
Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Lyon Part Dieu to Florence Santa Maria Novella is a bus with an average price of $44 (€36).
This is compared to other travel options from Lyon Part Dieu to Florence Santa Maria Novella:
A bus is $150 (€123) less than a flight for this route with tickets for a flight from Lyon Part Dieu to Florence Santa Maria Novella costing on average $193 (€159).
A bus is $177 (€145) less than a train for this route with tickets for a train from Lyon Part Dieu to Florence Santa Maria Novella costing on average $221 (€181).
The fastest way to travel from Lyon Part Dieu to Florence Santa Maria Novella is by flight with an average journey time of 1h 21m.
Other travel options to Florence Santa Maria Novella take longer:
Train takes on average 7h 17m.
Bus takes on average 10h 27m.
It's helpful to compare your options as there are 3 ways to travel between Lyon Part Dieu and Florence Santa Maria Novella including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Lyon Part Dieu to Florence Santa Maria Novella among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $221 (€181) compared to roughly $305 (€251) in fuel and tolls — a saving of about $84 (€69). The journey takes 7h 17m versus 7h 10m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Lyon Part Dieu to Florence Santa Maria Novella train times
The table below shows live departures for Lyon Part Dieu to Florence Santa Maria Novella trains for today, Saturday, July 11. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FRECCIAROSSA 1000 9281+9947 | 9:24 AM Lyon Part Dieu | 8h11 | 5:35 PM Florence Santa Maria Novella | 1 transfer | |
| FRECCIAROSSA 1000 9281+9951 | On time 9:24 AM Lyon Part Dieu | 9h11 | 6:35 PM Florence Santa Maria Novella | 1 transfer | |
| FRECCIAROSSA 1000 9281+9951 | On time 9:24 AM Lyon Part Dieu | 9h11 | 6:35 PM Florence Santa Maria Novella | 1 transfer | |
| FRECCIAROSSA 1000 9281+8143 | 9:24 AM Lyon Part Dieu | 7h11 | 4:35 PM Florence Santa Maria Novella | 1 transfer | |
| FRECCIAROSSA 1000 9281+9947 | 9:24 AM Lyon Part Dieu | 8h11 | 5:35 PM Florence Santa Maria Novella | 1 transfer | |
| FRECCIAROSSA 1000 9281+9959 | On time 9:24 AM Lyon Part Dieu | 11h11 | 8:35 PM Florence Santa Maria Novella | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon Part Dieu to Florence Santa Maria Novella by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Lyon Part Dieu to Florence Santa Maria Novella trains with Omio?
Trenitalia as well as SNCF | TGV INOUI or Regionale offer trains services from Lyon Part Dieu to Florence Santa Maria Novella.
Omio is an official ticket reseller for all your travel options from Lyon Part Dieu to Florence Santa Maria Novella.
Why book with Omio vs Trenitalia?
- Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of SNCF | TGV INOUI or Regionale to find the best option for your trip from Lyon Part Dieu to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon Part Dieu to Florence Santa Maria Novella.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon Part Dieu to Florence Santa Maria Novella.
Journey information
Overview: Train from Lyon Part Dieu to Florence Santa Maria Novella
France
Italy
Trains from Lyon Part Dieu to Florence Santa Maria Novella run on average 1 times per day, taking around 7h 17m. Cheap train tickets for this journey start at $221 (€181) but you can travel from only $20 (€16) by bus.
The earliest train runs at 08:31, the last at 08:31. The fastest train covers the 341 miles (550 km) distance in 7h 19m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $20 (€16)
Distance 341 miles (550 km) |
Average train duration 7h 17m |
Cheapest ticket price $221 (€181) |
Trains per day 1 |
Fastest train 7h 19m |
First train 8:31 AM |
Last train 8:31 AM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sun |
Least Busy Day Sun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $20 (€16)
Train companies: Trenitalia, SNCF | TGV INOUI, Regionale from Lyon Part Dieu to Florence Santa Maria Novella trainsTrenitalia, SNCF | TGV INOUI, Regionale trains will get you between Lyon Part Dieu and Florence Santa Maria Novella from $20 (€16). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
About
Trenitalia is not only Italy's national railroad company but also the country's largest train operator. Trenitalia’s fleet of trains ncludes the high-speed Frecciarossa, Frecciargento and Frecciabianca trains as well as intercity, regional and night trains. Bathrooms and WiFi access are standard on long-distance routes. In most cases, the trains also provide barrier-free access. Trenitalia offers different tickets, which vary in price and flexibility: Base, Economy, Super Economy and Ordinaria. You can even use Trenitalia discount cards on Omio. Make sure to look out for the latest offers from Trenitalia on Omio to score special deals!
Luggage & cancellation policy
Trenitalia frequency
1 a day
Luggage included
2 pieces of hand luggage per passenger included in ticket price
Luggage storage
Overhead racks, luggage areas at end of carriages, and spaces between seat backs
Cancellation Policy
Cancellation policies vary by ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car on high-speed trains, trolley service with snacks and beverages, vending machines on some trains
Seat reservation
Optional seat reservation, costs extra except on high-speed trains where it's mandatory and included
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available with advance notice
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, guide dogs travel free
Quiet zone
SNCF | TGV INOUI
About
SNCF's TGV INOUI is a premium high-speed train service operating across France and to other European cities. Launched in 2017, it aims to provide an enhanced travel experience with greater comfort, connectivity, and services compared to traditional TGV services. TGV INOUI trains offer features like adjustable seats, electrical outlets, fold-down tables, and dedicated luggage spaces. Passengers can enjoy onboard Wi-Fi and access to the TGV INOUI portal for entertainment and journey information. The service also includes a "Bistro TGV INOUI" for dining, with options for online ordering. SNCF is also introducing a new generation of TGV INOUI trains from 2026, which will be more modular, energy-efficient, and 97% recyclable.
Luggage & cancellation policy
Luggage included
1 hand luggage + 2 pieces of luggage free of charge
Luggage storage
Overhead racks, end of carriages, between seats
Cancellation Policy
Refund conditions depend on ticket type
Refund
Full refund if train canceled
Amenities on board the train
Wifi
Food sold onboard
Restaurant car (not all trains), at-seat service in 1st class, snack bar/cafe
Seat reservation
Second class: Optional, additional fee. First class: Included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, boarding assistance available
Pets
Small pets in carriers: Free. Large dogs: Paid ticket required. Guide dogs: Free
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
20h 52m
Cheapest Price
$101 (€83)
Regionale frequency
1 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Complete guide to Firenze Santa Maria Novella
Things to do in Firenze Santa Maria Novella
Discover the best of Firenze Santa Maria Novella — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Firenze Santa Maria Novella trip today.
- Must visit
Galleria dell'Accademia di Firenze
Best known for Michelangelo's David, this compact museum also holds important Florentine paintings and sculpture. Advance booking is commonly recommended.
- Recommended
Palazzo Pitti
Large palace museum complex with royal apartments, art collections, and access to the Boboli Gardens. A major stop for Medici history and grand interiors.
- Must visit
Piazza del Duomo
The ceremonial heart of Florence, packed with the cathedral, baptistery, and bell tower. Essential for first-time visitors and classic city views.
- Must visit
Piazza della Signoria
Historic square filled with civic symbolism, monumental sculpture, and constant activity. One of Florence's most recognizable public spaces.
- Must visit
Piazzale Michelangelo
The best-known panoramic terrace over Florence, especially popular at sunset and widely featured on social media. Excellent for skyline photography.
- Gluten-free
Bistecca Alla Fiorentina
Thick-cut T-bone steak from Chianina beef, grilled rare over coals. It is the signature Florentine dish and a classic of Tuscan cooking.
- Vegetarian
- Vegan
Ribollita
Hearty Tuscan soup of bread, cannellini beans, kale, and vegetables, traditionally reheated the next day. A beloved local peasant dish.
- Vegetarian
- Vegan
Pappa Al Pomodoro
Rustic tomato and bread soup with garlic, olive oil, and basil. It is a comforting Florentine staple made from simple Tuscan ingredients.
Enoteca Pinchiorri
Celebrated fine-dining destination with refined Italian cuisine and an exceptional wine program. Ideal for a special high-end meal in Florence.
Trattoria Mario
Historic, no-frills trattoria near the central market, known for Bistecca Alla Fiorentina, hearty Tuscan classics, and a lively local atmosphere.
Trattoria ZaZa
Popular long-running trattoria near Mercato Centrale with a broad Tuscan menu, traditional decor, and a busy, welcoming atmosphere.
Euro
Moderate for Italy: cafes and casual meals are manageable, but hotels and tourist-area dining near the station cost more.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or takeaway.
- Mid-range
- EUR 20-35 per person at a standard restaurant.
- Fine dining
- EUR 70+ per person at upscale restaurants.
- Coffee
- EUR 1.50-3 for espresso or cappuccino.
Tipping culture
Service is often included or covered by a coperto. Tipping is not required; round up or leave EUR 1-2 at cafes, 5-10% for great restaurant service.
at bus
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.70
- Day pass
- EUR 5.00
To the city center
Firenze Santa Maria Novella, Florence -> Piazza del Duomo, Florence
- Distance
- 1 km
- Travel time
- 10 min
- Single urban tickets on Autolinee Toscane city buses are time-limited and can also be bought in the official app before boarding.
- Card payment is available on many city buses via contactless tap, but validate your ticket or tap properly when required.
FAQs: Trains from Lyon Part Dieu to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Lyon Part Dieu to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.
Train ticket prices from Lyon Part Dieu to Florence Santa Maria Novella can vary. The cheapest ticket starts at $221 (€181), while the average price is around $221 (€181).
The train from Lyon Part Dieu to Florence Santa Maria Novella runs once a day and takes approximately 7h 19m.
The distance by train from Lyon Part Dieu to Florence Santa Maria Novella is 341 miles (550 km).
The first train from Lyon Part Dieu to Florence Santa Maria Novella leaves at 8:31 AM.
The last train from Lyon Part Dieu to Florence Santa Maria Novella leaves at 8:31 AM.
There is no high speed train available from Lyon Part Dieu to Florence Santa Maria Novella.
There is no direct train service currently available from Lyon Part Dieu to Florence Santa Maria Novella.
Unfortunately, there is no night train available from Lyon Part Dieu to Florence Santa Maria Novella.
The cheapest way to get from Lyon Part Dieu to Florence Santa Maria Novella is by bus, with a cost of around $20 (€16).
The train journey from Lyon Part Dieu to Firenze Santa Maria Novella is quite scenic, offering views of the picturesque French countryside, the majestic Alps, and the rolling hills of Tuscany, making it a visually delightful experience.
A day trip from Lyon Part Dieu to Firenze Santa Maria Novella is not feasible as the journey takes 7h 19m and the distance is 341 miles (550 km). The frequency of trains is 1 per day.
Yes, you can take the train from Lyon Part Dieu to Florence Santa Maria Novella.
Since both Lyon Part Dieu and Florence Santa Maria Novella are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Florence Santa Maria Novella include Pisa, Bologna, Siena, Lucca, Verona.
We recommend using the train as it is the most popular way to get from Lyon Part Dieu to Florence Santa Maria Novella among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
More options for your journey from Lyon Part Dieu to Florence Santa Maria Novella
Here are some other resources that might have the information you need
Most popular trains to and from Florence Santa Maria Novella and Lyon Part Dieu
Most popular train connections to Florence Santa Maria Novella
HomeTrainsTrains in ItalyTrain Times to Florence Santa Maria NovellaLyon Part Dieu to Florence Santa Maria Novella train
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