The cheapest and fastest trains from Karlsruhe to San Vincenzo
Cheapest price
$279
Average price
$279
Fastest journey
8 h 22 m
Average duration
8 h 52 m
Trains per day
5
Distance
678 km
The best way to find a cheap train ticket from Karlsruhe to San Vincenzo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to San Vincenzo will cost around $279 if you buy it on the day, but the cheapest tickets can be found for only $279.
It's difficult to get from Karlsruhe to San Vincenzo without transferring at least 3 times.
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Live departures
Karlsruhe to San Vincenzo train times
The table below shows live departures for Karlsruhe to San Vincenzo trains for tomorrow, Thursday, March 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:04 AM Karlsruhe | 9h49 | 1:53 PM Genova Brignole | 3 transfers | |
![]() | 7:01 AM Karlsruhe | 8h52 | 3:53 PM Genova Brignole | 3 transfers | |
![]() | 9:01 AM Karlsruhe | 8h52 | 5:53 PM Genova Brignole | 3 transfers | |
![]() | 11:01 AM Karlsruhe | 8h51 | 7:52 PM Genova Brignole | 3 transfers | |
![]() | 1:01 PM Karlsruhe | 9h23 | 10:24 PM Genova Brignole | 3 transfers |
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to San Vincenzo by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Why should you book Karlsruhe to San Vincenzo trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Train from Karlsruhe to San Vincenzo
Trains from Karlsruhe to San Vincenzo run on average 2 times per day, taking around 17h 47m. Cheap train tickets for this journey start at $338 (€274) if you book in advance.
The earliest train runs at 06:09, the last at 10:03. The fastest train covers the 421 miles (678 km) distance in 13h 36m.
Distance 421 miles (678 km) |
Average train duration 17h 47m |
Cheapest ticket price $338 (€274) |
Trains per day 2 |
Fastest train 13h 36m |
First train 06:09 |
Last train 10:03 |
Train companies: Deutsche Bahn from Karlsruhe to San Vincenzo trainsDeutsche Bahn trains will get you between Karlsruhe and San Vincenzo from $338 (€274). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FAQs: Trains from Karlsruhe to San Vincenzo
Find answers to the most common questions about traveling from Karlsruhe to San Vincenzo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at San Vincenzo, this guide helps you travel smarter and with confidence.

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