The cheapest and fastest trains from Karlsruhe to San Vincenzo
Cheapest price
$276
Average price
$281
Fastest journey
8 h 22 m
Average duration
8 h 52 m
Trains per day
7
Distance
678 km
The best way to find a cheap train ticket from Karlsruhe to San Vincenzo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to San Vincenzo will cost around $281 if you buy it on the day, but the cheapest tickets can be found for only $276.
It's difficult to get from Karlsruhe to San Vincenzo without transferring at least 3 times.
4:04 AM9h49Karlsruhe1:53 PMGenova Brignole$2761One-way3 transfers
7:01 AM8h52Karlsruhe3:53 PMGenova Brignole$2761One-way3 transfers
9:01 AM8h52Karlsruhe5:53 PMGenova Brignole$2761One-way3 transfers
11:01 AM8h51Karlsruhe7:52 PMGenova Brignole$2761One-way3 transfers
1:01 PM9h23Karlsruhe10:24 PMGenova Brignole$2761One-way3 transfers
3:01 PM8h22Karlsruhe11:23 PMBrignole$3091One-way3 transfers
11:01 AM8h51Karlsruhe7:52 PMGenova Brignole$2761One-way3 transfers
7:01 AM8h52Karlsruhe3:53 PMGenova Brignole$2761One-way3 transfers
9:01 AM8h52Karlsruhe5:53 PMGenova Brignole$2761One-way3 transfers
1:01 PM9h23Karlsruhe10:24 PMGenova Brignole$2761One-way3 transfers
Travel Information
Compare bus and train for Karlsruhe to San Vincenzo
Omio recommends booking the train as it is the most popular option from Karlsruhe to San Vincenzo among Omio's users. If you are prioritising price take the bus with prices starting from $72. For those with little time consider booking a train which can get you there in 9h 58m. The ticket price range depends on the travel mode: a bus costs an average of $72, and a train costs an average of $276.
Distance: 421 miles (678 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$284 Average price | $72 Average price Cheapest | $134 Average price (fuel + tolls) |
10h 28m Average total duration Fastest 9h 58m Onboard + 30m Additional time* | 12h 25m Average total duration 11h 55m Onboard + 30m Additional time* | 9h 41m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Karlsruhe to San Vincenzo:
A bus is $212 (€173) less than a train for this route with tickets for a train from Karlsruhe to San Vincenzo costing on average $284 (€232).
Other travel options to San Vincenzo take longer:
Bus takes on average 11h 55m.
Tickets start at around $284 (€232) compared to roughly $134 (€110) in fuel and tolls — a saving of about $-150.03 (€-122.68). The journey takes 9h 58m versus 9h 41m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Karlsruhe to San Vincenzo train times
The table below shows live departures for Karlsruhe to San Vincenzo trains for today, Thursday, June 18. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:01 PM Karlsruhe | 9h23 | 10:24 PM Genova Brignole | 3 transfers | |
![]() | 3:01 PM Karlsruhe | 8h22 | 11:23 PM Brignole | 3 transfers | |
![]() | 7:01 PM Karlsruhe | 14h52 | 9:53 AM Genova Brignole | 3 transfers | |
| Friday, June 19 | |||||
![]() | 4:04 AM Karlsruhe | 9h49 | 1:53 PM Genova Brignole | 3 transfers | |
![]() | 7:01 AM Karlsruhe | 8h52 | 3:53 PM Genova Brignole | 3 transfers | |
![]() | 9:01 AM Karlsruhe | 8h52 | 5:53 PM Genova Brignole | 3 transfers | |
![]() | 11:01 AM Karlsruhe | 8h51 | 7:52 PM Genova Brignole | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to San Vincenzo by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 19
Jun 20
Jun 21
Jun 22
Jun 23
Jun 24
Jun 25
Journey information
Overview: Train from Karlsruhe to San Vincenzo
Trains from Karlsruhe to San Vincenzo run on average 5 times per day, taking around 9h 58m. Cheap train tickets for this journey start at $276 (€226) but you can travel from only $72 (€59) by bus.
The earliest train runs at 06:09, the last at 10:03. The fastest train covers the 421 miles (678 km) distance in 8h 22m.
Distance 421 miles (678 km) |
Average train duration 9h 58m |
Cheapest ticket price $276 (€226) |
Trains per day 5 |
Fastest train 8h 22m |
First train 6:09 AM |
Last train 10:03 AM |
High Season Jan - Mar |
Low Season Apr - Jun |
Train companies: Deutsche Bahn Intercity (DB IC), Nederlandse Spoorwegen (NS) from Karlsruhe to San Vincenzo trainsDeutsche Bahn Intercity (DB IC), Nederlandse Spoorwegen (NS) trains will get you between Karlsruhe and San Vincenzo from $72 (€59). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn Intercity (DB IC)
Nederlandse Spoorwegen (NS)
FAQs: Trains from Karlsruhe to San Vincenzo
Find answers to the most common questions about traveling from Karlsruhe to San Vincenzo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at San Vincenzo, this guide helps you travel smarter and with confidence.

Most popular train connections from Karlsruhe
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