The cheapest and fastest trains from Jefferson City, MO to Chicago, IL
Cheapest price
$146
Average price
$146
Fastest journey
8 h 11 m
Average duration
8 h 11 m
Trains per day
1
Distance
529 km
The best way to find a cheap train ticket from Jefferson City, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jefferson City, MO to Chicago, IL will cost around $146 if you buy it on the day, but the cheapest tickets can be found for only $146.
Of the 1 trains that leave Jefferson City, MO for Chicago, IL on Thu, Nov 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 20 the direct trains cover the 529 km distance in an average of 8 h 11 m but if you time it right, some trains will get you there in just 8 h 11 m .
On Thu, Nov 20 the slowest trains will take 8 h 11 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Live departures
Jefferson City, MO to Chicago, IL train times
The table below shows live departures for Jefferson City, MO to Chicago, IL trains for today, Wednesday, November 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
318 Lincoln Service Missouri River Runner | 5:49 PM Jefferson City Station, Jefferson City, MO | 8h11 | 2:00 AM Chicago Union Station, Chicago, IL | 0 transfersDirect | |
318 Lincoln Service Missouri River Runner · 306 Lincoln Service | 5:49 PM Jefferson City Station, Jefferson City, MO | 10h54 | 4:43 AM Chicago Union Station, Chicago, IL | 1 transfer | |
| Thursday, November 20 | |||||
316 Missouri River Runner · 8359 AMTRAK · 58 City Of New Orleans | 1:12 AM Jefferson City Station, Jefferson City, MO | 14h03 | 3:15 PM Chicago Union Station, Chicago, IL | 2 transfers | |
![]() | 11:49 AM Jefferson City, MO | 8h11 | 8:00 PM Chicago, IL | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Jefferson City, MO to Chicago, IL by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 20
Nov 21
Nov 22
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Nov 24
Nov 25
Nov 26
Journey information
Overview: Train from Jefferson City, MO to Chicago, IL
Trains from Jefferson City, MO to Chicago, IL run on average 3 times per day, taking around 8h 29m. Cheap train tickets for this journey start at $147 (€119) if you book in advance.
There are 1 trains per day. The earliest train runs at 07:15, the last at 21:05. The fastest train covers the 328 miles (529 km) distance in 8h 11m.
Distance 328 miles (529 km) |
Average train duration 8h 29m |
Cheapest ticket price $147 (€119) |
Trains per day 3 |
Direct trains 1 |
Fastest train 8h 11m |
First train 07:15 |
Last train 21:05 |
Train companies: Amtrak from Jefferson City, MO to Chicago, IL trainsAmtrak trains will get you between Jefferson City, MO and Chicago, IL from $147 (€119). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Jefferson City, MO to Chicago, IL
Find answers to the most common questions about traveling from Jefferson City, MO to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Jefferson City, MO to Chicago, IL
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Ramps, restrooms.
- Courtyard Jefferson City
- Fairfield Inn & Suites Jefferson City
- Capitol Plaza Hotel
- Located in the main hall
- Free
- The station is located on the ground floor of the former Union Hotel.
- Bus: Local bus services available
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
Most popular train connections from Jefferson City, MO
More options for your journey from Jefferson City, MO to Chicago, IL
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