- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
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The cheapest and fastest buses from Jefferson City, MO to Chicago, IL
Showing times and prices for Aug 05
Cheapest price
€63
Average price
€67
Fastest journey
10 h 30 m
Average duration
14 h 30 m
Buses per day
2
Distance
529 km
Cheap tickets
The best way to find a cheap bus ticket from Jefferson City, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jefferson City, MO to Chicago, IL will cost around €67 if you buy it on the day, but the cheapest tickets can be found for only €63.
Fast buses
It's difficult to get from Jefferson City, MO to Chicago, IL without transferring at least once.
FlixBus+
7:15 PM10h30Jefferson City, Eastland Dr (Greyhound Bus Station), MO5:45 AMChicago, Greyhound Bus Station€631One-way1 transfer- · · 7:15 PM18h30Jefferson City, Eastland Dr (Greyhound Bus Station), MO1:45 PMChicago, Union Station (Amtrak), IL€721One-way2 transfers
- FlixBus+7:15 PM10h30Jefferson City, Eastland Dr (Greyhound Bus Station), MO5:45 AMChicago, Greyhound Bus Station€631One-way1 transfer
- · · 7:15 PM18h30Jefferson City, Eastland Dr (Greyhound Bus Station), MO1:45 PMChicago, Union Station (Amtrak), IL€721One-way2 transfers
Journey information
Overview: Bus from Jefferson City, MO to Chicago, IL
USAUSA
Buses from Jefferson City, MO to Chicago, IL run on average 3 times per day, taking around 13h 26m. Cheap bus tickets for this journey start at €49 but you can travel from only €36 by train.
The earliest bus runs at 00:15, the last at 23:45. The fastest bus covers the 328 miles (529 km) distance in 10h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €36
Distance 328 miles (529 km) |
Average bus duration 13h 26m |
Cheapest ticket price €49 |
Buses per day 3 |
Fastest bus 10h 30m |
First bus 12:15 AM |
Last bus 11:45 PM |
Cheapest Month Oct |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €36
Jefferson City, MO to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 07:10PM | Duration 18h55 | Departure days Wed | Cheapest price €66 |
Operator FlixBus | Departure Time 12:15AM | Arrival Time 10:45AM | Duration 10h30 | Departure days Mon, Tue, Fri, Sat | Cheapest price €96 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 11:45AM | Duration 10h30 | Departure days Mon, Tue, Fri, Sat | Cheapest price €79 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 08:10PM | Duration 18h55 | Departure days Wed | Cheapest price €147 |
Operator FlixBus | Departure Time 07:15PM | Arrival Time 05:45AM | Duration 10h30 | Departure days Wed, Sat | Cheapest price €63 |
Operator Greyhound | Departure Time 07:15PM | Arrival Time 01:45PM | Duration 18h30 | Departure days Wed, Sat | Cheapest price €72 |
Complete guide to Chicago, IL
Things to do in Chicago, IL
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
- Must visit
Field Museum
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
- Must visit
Museum of Science and Industry
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
- Must visit
Millennium Park
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
- Must visit
Magnificent Mile
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
- Must visit
Chicago Riverwalk
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-Dish Pizza
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
Chicago-Style Hot Dog
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian Beef Sandwich
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Johnnie's Beef
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Superdawg Drive-In
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
Alinea
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
US dollar ($)
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
FAQs: Bus from Jefferson City, MO to Chicago, IL
Find answers to the most common questions about traveling from Jefferson City, MO to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Jefferson City, MO to Chicago, IL can start from as little as €49 when you book in advance. The average bus ticket price for Jefferson City, MO to Chicago, IL is €99 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Jefferson City, MO to Chicago, IL is 10h 30m to travel the 328 miles (529 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Jefferson City, MO to Chicago, IL leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Jefferson City, MO to Chicago, IL leaves at 11:45 PM.
It's helpful to compare your options as there are 3 ways to travel between Jefferson City, MO and Chicago, IL including taking a train, bus, and flight.
No, there are no bathrooms on board the bus from Jefferson City, MO to Chicago, IL.
No, the bus from Jefferson City, MO to Chicago, IL has no accessibility options.
No, bikes are not allowed on board the bus from Jefferson City, MO to Chicago, IL.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Jefferson City, MO to Chicago, IL.
No, luggage for the bus from Jefferson City, MO to Chicago, IL needs to be booked in addition.
No, there are no additional luggage options for the bus from Jefferson City, MO to Chicago, IL.
Unfortunately, pets are not allowed on the bus from Jefferson City, MO to Chicago, IL.
No, there are no USB plugs on board the bus from Jefferson City, MO to Chicago, IL.
No, there is no WiFi on board the bus from Jefferson City, MO to Chicago, IL.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Chicago, IL, travelers should be cautious of pickpocketing and purse snatching, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and distraction thefts. It is advisable to stay alert in neighborhoods outside downtown after dark and use authorized transportation services to avoid unlicensed taxi scams. Keeping valuables secure and being aware of surroundings helps mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Jefferson City, MO to Chicago, IL
Most Jefferson City, MO to Chicago, IL buses use the Jefferson City, Eastland Dr (Greyhound Bus Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Jefferson City, MO and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Jefferson City
Arrival bus stations in Chicago
Jefferson City, Eastland Dr (Greyhound Bus Station)
Chicago, Greyhound Bus Station
City-centre transport
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Bus7 · 8m · €3 · every ~6 min
Chicago, Union Station (Amtrak)
City-centre transport
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Bus28, 151 · 7m · €3 · every ~13 min
Chicago, 95th Red Line Station
City-centre transport
Getting to Chicago, 95th Red Line Station from Chicago city centre
BusGreyhound US0100 · 20m · €2
29 · 47m · €3 · every ~11 min
29 · 48m · €3 · every ~11 min
SubwayRed Line · 24m · €5 · every ~23 min
Red Line · 25m · €5 · every ~23 min
More options for your journey from Jefferson City, MO to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and Jefferson City, MO
Most popular bus connections to Chicago, IL
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