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Jefferson City, MO to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:15PM | Arrival Time 05:45AM | Duration 10h30 | Departure days Sat | Cheapest price $133 |
Operator Greyhound | Departure Time 07:15PM | Arrival Time 02:10PM | Duration 18h55 | Departure days Tue, Wed, Sat | Cheapest price $126 |
Live departures
Jefferson City, MO to Chicago, IL bus times
The table below shows live departures for Jefferson City, MO to Chicago, IL buses for tomorrow, Thursday, February 5. You can also manually refresh the results below to see updated bus journeys.
Last updated at 4:34 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 undefined · undefined · undefined | 1:15 AM Jefferson City, Eastland Dr (Greyhound Bus Station), MO | 18h55 | 8:10 PM Chicago, Union Station (Amtrak), IL | 2 transfers | |
| undefined · undefined · undefined | 1:15 AM Jefferson City, Eastland Dr (Greyhound Bus Station), MO | 19h20 | 8:35 PM Chicago, Greyhound Bus Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Jefferson City, MO to Chicago, IL by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Jefferson City, MO to Chicago, IL
USAUSA
Take a bus from Jefferson City, MO to Chicago, IL and enjoy the approximately 328 miles (529 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 00:15, the last at 23:50.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $150 (€119)
Distance 328 miles (529 km) |
Buses per day 3 |
First bus 00:15 |
Last bus 23:50 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $150 (€119)
FAQs: Bus from Jefferson City, MO to Chicago, IL
Find answers to the most common questions about traveling from Jefferson City, MO to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
The earliest bus from Jefferson City, MO to Chicago, IL leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Jefferson City, MO to Chicago, IL leaves at 11:50 PM.
Yes, you can take a train between Jefferson City, MO and Chicago, IL.
No, the bus from Jefferson City, MO to Chicago, IL has no accessibility options.
No, there are no bathrooms on board the bus from Jefferson City, MO to Chicago, IL.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
No, bikes are not allowed on board the bus from Jefferson City, MO to Chicago, IL.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Jefferson City, MO to Chicago, IL.
No, luggage for the bus from Jefferson City, MO to Chicago, IL needs to be booked in addition.
No, there are no additional luggage options for the bus from Jefferson City, MO to Chicago, IL.
Unfortunately, pets are not allowed on the bus from Jefferson City, MO to Chicago, IL.
No, there are no USB plugs on board the bus from Jefferson City, MO to Chicago, IL.
No, there is no WiFi on board the bus from Jefferson City, MO to Chicago, IL.
popular bus stations
Popular bus stations from Jefferson City, MO to Chicago, IL
Jefferson City
Chicago
The major bus station for departures in Jefferson City is Jefferson City, Eastland Dr (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Jefferson City, Eastland Dr (Greyhound Bus Station) for your trip from Jefferson City to Chicago.
Jefferson City, Eastland Dr (Greyhound Bus Station)
information
The major bus station for arrivals in Chicago is Chicago, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Chicago, Greyhound Bus Station for your trip to Chicago from Jefferson City.
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information
Chicago, 95th Red Line Station
information
More options for your journey from Jefferson City, MO to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and Jefferson City, MO
Most popular bus connections to Chicago, IL
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