4.9
4.6
Travel Information
Compare train, bus, and flight for Jefferson City, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from Jefferson City, MO to Chicago, IL among Omio's users. If you are prioritising price, take the train, with an average ticket price of $91 For those with little time, consider booking a flight, which has an average total journey time of 6h 25m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a train costs an average of $91, while a flight costs an average of $623.
Distance: 328 miles (529 km)
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$91 Average price Cheapest | $623 Average price | $101 Average price | $78 Average price (fuel + tolls) |
8h 22m Average total duration 7h 52m Onboard + 30m Additional time* | 6h 25m Average total duration Fastest 4h 25m Onboard + 2h 0m Additional time* | 11h 53m Average total duration 11h 23m Onboard + 30m Additional time* | 6h 14m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | - CO2 emissions | 0.5 - 1.3kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Jefferson City, MO to Chicago, IL:
A train is $9 (€8) less than a bus for this route with tickets for a bus from Jefferson City, MO to Chicago, IL costing on average $101 (€85).
A train is $532 (€446) less than a flight for this route with tickets for a flight from Jefferson City, MO to Chicago, IL costing on average $623 (€522).
Other travel options to Chicago, IL take longer:
Train takes on average 8h 22m.
Bus takes on average 11h 53m.
Tickets start at around $91 (€77) compared to roughly $78 (€65) in fuel and tolls — a saving of about $-13.54 (€-11.35). The journey takes 7h 52m versus 6h 14m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Jefferson City, MO to Chicago, IL
How to get from Jefferson City, MO to Chicago, IL by train, bus or flight.
Our recommendation
The best way to travel from Jefferson City, MO to Chicago, IL is by taking a bus because it’s the best combination of price and speed.
- · · 7:15 PM18h30Jefferson City, Eastland Dr (Greyhound Bus Station), MO1:45 PMChicago, Union Station (Amtrak), IL$1061One-way2 transfers
Cheapest
- · · 7:15 PM18h30Jefferson City, Eastland Dr (Greyhound Bus Station), MO1:45 PMChicago, Union Station (Amtrak), IL$1061One-way2 transfers
Fastest
AA366210:40 AM1h34Columbia Regional Airport12:14 PMO'Hare International Airport$4561One-way0 transfers
Other options
- 318 Lincoln Service Missouri River Runner · 306 Lincoln Service11:49 AM10h54Jefferson City Station, Jefferson City, MO10:43 PMChicago Union Station, Chicago, IL$1441One-way1 transfer
- 316 Missouri River Runner · 8359 Connecting Bus · 58 City Of New Orleans7:12 PM36h03Jefferson City Station, Jefferson City, MO7:15 AMChicago Union Station, Chicago, IL$1621One-way2 transfers
- 318 Lincoln Service Missouri River Runner11:49 AM8h11Jefferson City Station, Jefferson City, MO8:00 PMChicago Union Station, Chicago, IL$1961One-way0 transfers
- · · 7:15 PM18h55Jefferson City, Eastland Dr (Greyhound Bus Station), MO2:10 PMChicago, Greyhound Bus Station$1061One-way2 transfers
- AA36556:00 AM1h38Columbia Regional Airport7:38 AMO'Hare International Airport$4561One-way0 transfers
- AA33986:24 PM1h46Columbia Regional Airport8:10 PMO'Hare International Airport$4561One-way0 transfers
- AA3402 · AA37905:14 PM5h46Columbia Regional Airport11:00 PMO'Hare International Airport$4661One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Oct 11
Oct 12
Oct 13
Oct 14
Oct 15
Oct 16
Oct 17
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Jefferson City, MO to Chicago, IL
Travel to Chicago, IL easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Jefferson City, MO to Chicago, IL.
This is compared to other travel options from Jefferson City, MO to Chicago, IL:
A train is $9 (€8) less than a bus for this route with tickets for a bus from Jefferson City, MO to Chicago, IL costing on average $101 (€85).
A train is $532 (€446) less than a flight for this route with tickets for a flight from Jefferson City, MO to Chicago, IL costing on average $623 (€522).
Other travel options to Chicago, IL take longer:
Train takes on average 8h 22m.
Bus takes on average 11h 53m.
- Around 29 flights per day.
- Around 2 trains per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Jefferson City, MO and Chicago, IL as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Columbia Regional Airport and arrive in O'Hare International Airport.
- Trains mostly depart from Jefferson City Station, Jefferson City, MO and arrive in Chicago Union Station, Chicago, IL.
- Buses mostly depart from Jefferson City, Eastland Dr (Greyhound Bus Station), MO and arrive in Chicago, Greyhound Bus Station.
- Travel with United, American Airlines to go to Chicago, IL by flight.
- Travel with Greyhound, FlixBus to go to Chicago, IL by bus.
- Travel with Amtrak to go to Chicago, IL by train.
- 3 direct flights per day with United.
- 1 direct trains per day with Amtrak.
Travelling from Jefferson City, MO to Chicago, IL: related information
Here are some other resources that might have the information you need
Travel to popular destinations by train, bus or flight
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
