- Must visit
Pinacoteca di Brera
Milan’s premier fine art gallery, known for masterpieces by Raphael, Caravaggio, and Mantegna. A top choice for Italian art lovers.
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The cheapest and fastest trains from Isernia station to Milan
Showing times and prices for Jun 26
Cheapest price
$120
Average price
$127
Fastest journey
5 h 35 m
Average duration
5 h 52 m
Trains per day
4
Distance
592 km
Cheap tickets
The best way to find a cheap train ticket from Isernia station to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Isernia station to Milan will cost around $127 if you buy it on the day, but the cheapest tickets can be found for only $120.
Fast trains
It's difficult to get from Isernia station to Milan without transferring at least once.
6:40 AM5h35Isernia station12:15 PMMilan$1201One-way1 transfer- 8:38 AM5h37Isernia station2:15 PMMilan$1201One-way1 transfer
- 6:00 PM6h20Isernia station12:20 AMMilan$1201One-way1 transfer
- 3:03 PM5h57Isernia station9:00 PMMilan$1501One-way1 transfer
- 6:40 AM5h35Isernia station12:15 PMMilan$1201One-way1 transfer
- 8:38 AM5h37Isernia station2:15 PMMilan$1201One-way1 transfer
- 3:03 PM5h57Isernia station9:00 PMMilan$1501One-way1 transfer
- 6:00 PM6h20Isernia station12:20 AMMilan$1201One-way1 transfer
Travel Information
Compare train, bus, and flight for Isernia station to Milan
Omio recommends booking the train as it is the most popular option from Isernia station to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 30m. The ticket price range depends on the travel mode: a bus costs an average of $32, and a train costs an average of $61.
Distance: 367 miles (592 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$61 Average price | $32 Average price Cheapest | $54 Average price | $141 Average price (fuel + tolls) |
6h 20m Average total duration 5h 50m Onboard + 30m Additional time* | 13h 50m Average total duration 13h 20m Onboard + 30m Additional time* | 4h 30m Average total duration Fastest 1h 30m Onboard + 3h 0m Additional time* | 7h 33m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Isernia station to Milan is a bus with an average price of $32 (€26).
This is compared to other travel options from Isernia station to Milan:
A bus is $22 (€19) less than a flight for this route with tickets for a flight from Isernia station to Milan costing on average $54 (€45).
A bus is $29 (€24) less than a train for this route with tickets for a train from Isernia station to Milan costing on average $61 (€51).
The fastest way to travel from Isernia station to Milan is by flight with an average journey time of 1h 30m.
Other travel options to Milan take longer:
Train takes on average 5h 50m.
Bus takes on average 13h 20m.
It's helpful to compare your options as there are 3 ways to travel between Isernia station and Milan including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Isernia station to Milan among Omio's users.
Take the train. On this route, it beats driving on both time and money.
The journey is about 1h 43m faster (5h 50m by train vs 7h 33m by car) and roughly $80 (€66) cheaper once you factor in fuel and tolls ($61 (€51) vs $141 (€117)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Live departures
Isernia station to Milan train times
The table below shows live departures for Isernia station to Milan trains for today, Thursday, June 25. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 6:40 AM Isernia station | 5h35 | 12:15 PM Milan | 1 transfer | |
| 8:38 AM Isernia station | 5h37 | 2:15 PM Milan | 1 transfer | |
| 3:03 PM Isernia station | 5h57 | 9:00 PM Milan | 1 transfer | |
| 6:00 PM Isernia station | 6h20 | 12:20 AM Milan | 1 transfer | |
| 8:35 PM Isernia station | 11h55 | 8:30 AM Milan | 1 transfer |
Find all the dates and times for this journey
Compare prices and tickets Isernia station to Milan by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Isernia station to Milan trains with Omio?
Frecciarossa as well as Regionale offer trains services from Isernia station to Milan.
Omio is an official ticket reseller for all your travel options from Isernia station to Milan.
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Regionale to find the best option for your trip from Isernia station to Milan.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Isernia station to Milan.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Isernia station to Milan.
Journey information
Overview: Train from Isernia station to Milan
ItalyItaly
Trains from Isernia station to Milan run on average 7 times per day, taking around 5h 50m. Cheap train tickets for this journey start at $61 (€51) but you can travel from only $32 (€26) by bus.
The earliest train runs at 06:10, the last at 06:10. The fastest train covers the 367 miles (592 km) distance in 12h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $32 (€26)
Distance 367 miles (592 km) |
Average train duration 5h 50m |
Cheapest ticket price $61 (€51) |
Trains per day 7 |
Fastest train 12h 15m |
First train 6:10 AM |
Last train 6:10 AM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $32 (€26)
Train companies: Frecciarossa, Regionale from Isernia station to Milan trainsFrecciarossa, Regionale trains will get you between Isernia station and Milan from $32 (€26). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
6h 22m
Cheapest Price
$103 (€85)
Frecciarossa frequency
6 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
5h 33m
Cheapest Price
$120 (€99)
Regionale frequency
1 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Complete guide to Milan
Things to do in Milan
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
- Must visit
Fondazione Prada
Contemporary art venue in a striking converted distillery complex, widely popular for exhibitions and architecture.
- Recommended
Museo del Novecento
Major museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist and modern collections.
- Must visit
Navigli
Canal-side district famous for walks, historic waterways, and photogenic corners. Highly popular with visitors and on social media.
- Must visit
Brera
Charming central neighborhood with elegant streets, art atmosphere, independent shops, and classic Milan character.
- Must visit
Piazza del Duomo
Milan’s main square and urban heart, surrounded by major landmarks and ideal as a starting point for exploring the city.
- Vegetarian
- Gluten-free
Risotto Alla Milanese
Milan’s signature saffron risotto, rich with butter and cheese. It is one of the city’s most iconic dishes and a classic of Lombard cuisine.
Cotoletta Alla Milanese
A breaded veal cutlet fried in butter, traditionally served bone-in. It is one of Milan’s best-known historic dishes.
- Gluten-free
Ossobuco
Braised veal shanks, often served with risotto alla Milanese. The marrow, tender meat, and slow-cooked sauce make it a Milanese favorite.
Luini
A famous casual stop near the Duomo, best known for its panzerotti. It is not strictly Milanese cuisine but is one of the city’s most iconic quick bites.
Ratanà
A respected modern Milanese restaurant known for refined Lombard dishes such as risotto and mondeghili in a stylish but relaxed setting.
Antica Trattoria Della Pesa
A long-established traditional trattoria serving classic Milanese cuisine, including ossobuco and cotoletta, in a historic atmosphere.
Euro
Prices are high by Italian standards, especially for hotels and central dining, though cafés, transit, and casual meals remain manageable.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or street food.
- Mid-range
- EUR 20-40 per person at a standard restaurant.
- Fine dining
- EUR 80+ per person at upscale restaurants.
- Coffee
- EUR 1.50-3 for espresso or cappuccino.
Tipping culture
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave 5-10% for good restaurant service. Small change is fine for cafés and taxis.
ATM Milano Official App
Get the appOfficial public transport app
Prices
- Single ticket
- 2.20 EUR
- Day pass
- 7.60 EUR
To the city center
Milan Centrale, Milan -> Duomo di Milano, Milan
- Distance
- 3 km
- Travel time
- 10 min
- Validate your ticket before boarding and keep it until the end of the trip, as inspections are frequent.
- You can pay contactless by card or device on Milan metro gates and on many buses and trams using ATM's tap-in system.
FAQs: Trains from Isernia station to Milan
Find answers to the most common questions about traveling from Isernia station to Milan by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.
Train ticket prices from Isernia station to Milan can vary. The cheapest ticket starts at $61 (€51), while the average price is around $61 (€51).
The train from Isernia station to Milan takes 12h 15m and runs 7 per day.
The distance by train from Isernia station to Milan is 367 miles (592 km).
The first train from Isernia station to Milan leaves at 6:10 AM.
The last train from Isernia station to Milan leaves at 6:10 AM.
Yes, there is a high-speed train from Isernia station to Milan.
There is no direct train service currently available from Isernia station to Milan.
Unfortunately, there is no night train available from Isernia station to Milan.
The cheapest way to get from Isernia station to Milan is by bus, with a cost of around $32 (€26).
The train journey from Isernia to Milan offers varied scenery, initially showcasing the mountainous landscapes of the Molise region and the rolling hills of Central Italy, before transitioning to the urban and industrial views as it approaches Milan.
A day trip from Isernia to Milan is not feasible as the journey takes 12h 15m. There are 10 train trips available per day for this route.
In Milan, you can visit the iconic Duomo di Milano for its stunning Gothic architecture and panoramic views, explore Leonardo da Vinci's The Last Supper at the Convent of Santa Maria delle Grazie, and stroll through the historic Galleria Vittorio Emanuele II with its luxury boutiques. Discover the grand Sforza Castle, which houses various museums and art collections, and relax in the serene Sempione Park near the city center.
To fully experience Milan's key attractions, including the Duomo, The Last Supper, and shopping in the fashion district, plan for around 3 to 4 days.
Yes, you can take the train from Isernia station to Milan.
Since both Isernia station and Milan are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Milan include Como, Varenna, Turin, Bergamo, Genoa.
We recommend using the train as it is the most popular way to get from Isernia station to Milan among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Milan, travelers should be cautious of pickpocketing, especially in crowded areas like public transportation, popular tourist sites, and busy shopping streets such as Corso Buenos Aires. Common scams include distraction techniques used by groups to steal wallets or phones, and fake charity collectors near landmarks. It's advisable to avoid unlicensed taxi services and to confirm fares beforehand. Staying alert and securing valuables can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Isernia station to Milan
Isernia
Milan
The major train station for departures in Isernia is Isernia. Find all the information you need to know about services, amenities and connections at Isernia for your trip from Isernia to Milan.
Amenities at train station
Wifi
Lockers
Parking
Dining
Taxis
Accessibility
WC
Hotel
Lost and Found Office
Ticket Office
Bike Parking
Information Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 8:00 PM Monday - Sunday
Number of platforms
2Wifi
- Free
Parking
- Parking is available 24/7 with access from Via Giovanni XXIII
Dining
- Pasta e Pizza
- Ristorante da Adriano
Taxis
- Outside the main entrance
Accessibility
- Ramps
WC
- €0.50
Hotel
- Grand Hotel Europa
- Hotel Ristorante Sayonara
- Hotel La Tequila
Lost and Found Office
- Located in the main hall
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for regional trains
Public transit options for Isernia
- Bus: Several local lines available
- Train: Regional connections
The major train station for arrivals in Milan is Milano Centrale. Find all the information you need to know about services, amenities and connections at Milano Centrale for your journey to Milan from Isernia.
Amenities at train station
WifiLockersParkingDining
ATMTaxisAccessibilityWCHotelTicket OfficeBike Parking
Bike Rental
Car RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 05:50 - 22:20
Distance to city center
2 kmWifi
- Free WiFi in the station
Lockers
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00
Dining
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
Accessibility
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4
Hotel
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
Ticket Office
- Mon - Sun: 05:50 - 22:20
Information Desk
- Located next to the ticket office on the ground floor in the shopping gallery
Public transit options for Milano Centrale
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Amenities at train station
WifiParkingDiningATMTaxisAccessibilityWCHotelBike ParkingBike Rentalinformation
Distance to city center
2 kmWifi
- Free Wi-Fi in the station
Dining
- Caffeteria Panni Caldi
- Princi
- Burgez
- Bricco Café
- U! Come tu mi vuoi
- Autogrill
- Culto
Accessibility
- Accessible facilities such as ticket machines, toilets, and ramps and additional assistance as needed from 07:45 to 22:30
Hotel
- Hotel NH Milano Palazzo Moscova
- AC Hotel by Marriott Milano
- Tocq Hotel
Public transit options for Milano Porta Garibaldi
- Metro lines: M2, M5
- Bus lines: 43, 56, 70, 94
- Train lines: R21, R31, S1, S11, S2, S5, S7, S8
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
5 kmNumber of platforms
8Wifi
- Free
Parking
- The car park is open 7 days a week, 24 hours a day. Access is available from Via G Battista Cassinis
Dining
- Ristorante Pizzeria Il Moro
- Osteria La Piola
Taxis
- Outside the main entrance
Accessibility
- Elevators, ramps
WC
- €1
Hotel
- Starhotels Business Palace
- Hotel Mistral
- Hotel Brenta Milano
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platforms 1-8 for trains to various destinations
- Hall 2: metro connections
Public transit options for Milano Rogoredo
- Metro: Line M3
- Bus: Several lines available
- Train: Regional and high-speed services
More options for your journey from Isernia station to Milan
Here are some other resources that might have the information you need
Most popular trains to and from Milan and Isernia station
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