- Must visit
Cleveland Museum of Art
World-class art museum famed for encyclopedic collections, free general admission, and standout holdings from ancient to contemporary art.
Omio recommends booking the train as it is the most popular option from Florence, SC to Cleveland, OH among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $173 For those with little time, consider booking a train, which has an average total journey time of 22h 8m. Average ticket prices depend on the travel mode: a bus costs an average of $173, while a train costs an average of $362.
Distance: 515 miles (830 km)
Most popular Train | Bus | Driving |
|---|---|---|
$362 Average price | $173 Average price Cheapest | $126 Average price (fuel + tolls) |
22h 8m Average total duration Fastest 21h 38m Onboard + 30m Additional time* | 25h 18m Average total duration 24h 48m Onboard + 30m Additional time* | 9h 53m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence, SC to Cleveland, OH:
A bus is $189 less than a train for this route with tickets for a train from Florence, SC to Cleveland, OH costing on average $362.
Other travel options to Cleveland, OH take longer:
Bus takes on average 24h 48m.
Tickets start at around $362 compared to roughly $126 in fuel and tolls — a saving of about $-236.35. The journey takes 21h 38m versus 9h 53m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Florence, SC to Cleveland, OH run on average 2 times per day, taking around 21h 38m. Cheap train tickets for this journey start at $297 but you can travel from only $96 by bus.
The earliest train runs at 01:54, the last at 23:32. The fastest train covers the 515 miles (830 km) distance in 18h 49m.
Distance 515 miles (830 km) |
Average train duration 21h 38m |
Cheapest ticket price $297 |
Trains per day 2 |
Fastest train 18h 49m |
First train 1:54 AM |
Last train 11:32 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Cleveland, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Cleveland, OH trip today.
World-class art museum famed for encyclopedic collections, free general admission, and standout holdings from ancient to contemporary art.
Major music museum celebrating rock history with iconic artifacts, immersive exhibits, and strong appeal for first-time visitors.
Excellent science museum with hands-on exhibits, a planetarium, and family-friendly learning in a restored historic mansion setting.
Historic neighborhood known for walkable streets, breweries, galleries, and one of the city’s most local-feeling main corridors.
Flagship urban park with lakefront trails, beaches, gardens, and broad recreation space close to downtown.
Elegant cultural district anchored by museums, gardens, and classic architecture, ideal for a full day of walking and sightseeing.
A Cleveland staple of kielbasa, French fries, barbecue sauce, and slaw stuffed in a bun. It reflects the city's Eastern European and blue-collar food traditions.
Hearty Slovak-style stuffed cabbage rolls baked in tomato sauce. They are traditional in many Cleveland immigrant families and church festival menus.
Crisp potato pancakes often served with applesauce or sour cream. They are closely tied to Cleveland's strong Central and Eastern European heritage.
Beloved deli famous for towering corned beef sandwiches. Casual, no-frills, and widely considered a Cleveland institution.
Historic Ohio City brewpub known for Cleveland beer culture, sausages, pretzels, and hearty pub fare in a lively, landmark setting.
Refined farm-to-table restaurant in Ohio City serving seasonal American dishes with polished service and a warm neighborhood atmosphere.
Moderate for U.S. city travel: hotels and dining are usually cheaper than New York or Chicago, while transit and attractions are generally manageable for visitors.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is good.
Find answers to the most common questions about traveling from Florence, SC to Cleveland, OH by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Cleveland, OH, this guide helps you travel smarter and with confidence.

Most Florence, SC to Cleveland, OH trains use the Florence Station to Cleveland Amtrak station pair. Use this guide to compare Florence, SC and Cleveland, OH train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink options are available at Florence Station.
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage storage is available at Florence Station. Lost and found is available at the station.
Available at Florence Station: Parking, Taxis, WC.
Accessibility facilities are available at Florence Station: Elevators, ramps.
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
Cleveland Amtrak has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Lost and Found Office, Ticket Office, Bike Rental, Information Desk, and Luggage Carts.
Food and drink options are available at Cleveland Amtrak.
Ticket office support is available at Cleveland Amtrak. Information desks are located in the main hall.
Luggage storage is available at Cleveland Amtrak. Lost and found is available at the station.
Available at Cleveland Amtrak: Parking, Taxis, WC.
Available at Cleveland Amtrak: Bike Rental.
Accessibility facilities are available at Cleveland Amtrak.
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