Florence, SC to Fort Myers, FL train with Amtrak

Sun, Jun 21
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Amtrak
Regionale
Deutsche Bahn
iryo
Frecciarossa
2,000+ travel companies
Amtrak
Regionale
Deutsche Bahn
iryo
Frecciarossa
2,000+ travel companies
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Travel Information

Compare bus for Florence, SC to Fort Myers, FL

Omio recommends booking the bus as it is the most popular option from Florence, SC to Fort Myers, FL among Omio's users. If you are prioritising price take the bus with prices starting from $114. For those with little time consider booking a bus which can get you there in 18h 20m. The ticket price range depends on the travel mode: a bus costs an average of $114, and a bus costs an average of $114.

Distance: 537 miles (865 km)

Compare bus with

Most popular
Bus
Driving

$114

Average price

Cheapest

$122

Average price

(fuel + tolls)

18h 50m

Average total duration

Fastest

18h 20m

Onboard

+

30m

Additional time*

9h 11m

Average total duration

(door-to-door)

Direct Options

Direct Options

The cheapest way to travel from Florence, SC to Fort Myers, FL is a bus with an average price of $114 (€93).
The fastest way to travel from Florence, SC to Fort Myers, FL is by train with an average journey time of 15h 31m.

Other travel options to Fort Myers, FL take longer:

Bus takes on average 18h 20m.

Yes, you can take a bus between Florence, SC and Fort Myers, FL.
We recommend using the train as it is the most popular way to get from Florence, SC to Fort Myers, FL among Omio's users.

Compare prices and tickets Florence, SC to Fort Myers, FL by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Jun 21
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Journey information

Overview: Train from Florence, SC to Fort Myers, FL

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Take a train from Florence, SC to Fort Myers, FL and enjoy the approximately 537 miles (865 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest train runs at 07:00, the last at 07:00.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $114 (€93)
Distance
537 miles (865 km)
Average train duration
15h 31m
Trains per day
2
First train
7:00 AM
Last train
7:00 AM
Cheapest Month
Nov
Cheapest Day
Sat
High Season
Apr - Jun
Low Season
Jan - Mar
Best time to book
4 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $114 (€93)

Train companies: Amtrak from Florence, SC to Fort Myers, FL trainsAmtrak trains will get you between Florence, SC and Fort Myers, FL from $114 (€93). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Amtrak

About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
22h 58m
Cheapest Price
$177 (€144)
Amtrak frequency
2 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone

Complete guide to Fort Myers

Things to do in Fort Myers

Discover the best of Fort Myers — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Fort Myers trip today.

  • Must visit

Edison and Ford Winter Estates

Historic riverfront estate museum with Thomas Edison and Henry Ford homes, gardens, and a large inventions museum. One of Fort Myers' signature cultural attractions.

  • Recommended

IMAG History & Science Center

Family-friendly science and local history museum with interactive exhibits, aquariums, and hands-on learning. Popular for visitors with children.

  • Recommended

Sidney & Berne Davis Art Center

Downtown visual and performing arts venue hosting exhibitions, events, and community programming in a restored historic federal building.

United States Dollar

Moderate by U.S. standards. Casual dining is affordable, but beach areas, hotels, and seasonal travel can raise costs noticeably.

Average meal costs

Budget
USD 10-18 for fast food or a casual lunch.
Mid-range
USD 20-40 per person at a mid-range restaurant.
Fine dining
USD 60-120+ per person at upscale restaurants.
Coffee
USD 3-6 for drip coffee or a latte.

Tipping culture

Tip 18-20% in restaurants; 20%+ for excellent service. Bartenders: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Not usually needed for fast food.

FAQs: Trains from Florence, SC to Fort Myers, FL

Find answers to the most common questions about traveling from Florence, SC to Fort Myers, FL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.

FAQs
The distance by train from Florence, SC to Fort Myers, FL is 537 miles (865 km).
The first train from Florence, SC to Fort Myers, FL leaves at 7:00 AM.
The last train from Florence, SC to Fort Myers, FL leaves at 7:00 AM.
There is no high speed train available from Florence, SC to Fort Myers, FL.
There is no direct train service currently available from Florence, SC to Fort Myers, FL.
Unfortunately, there is no night train available from Florence, SC to Fort Myers, FL.
The cheapest way to get from Florence, SC to Fort Myers, FL is by bus, with a cost of around $114 (€93).
The train journey from Florence, SC to Fort Myers, FL offers a blend of urban and rural landscapes, passing through charming Southern towns and offering views of the Carolinas’ lush greenery and some coastal areas, though it may not be traditionally considered one of the most scenic routes in the U.S.
For a well-rounded experience in Fort Myers, FL, three to four days are recommended to explore its beautiful beaches, visit the Edison and Ford Winter Estates, and enjoy local dining and shopping options.
Yes, you can take the train from Florence, SC to Fort Myers, FL.
Since neither Florence, SC nor Fort Myers, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Florence, SC to Fort Myers, FL among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Fort Myers, FL, travelers should be cautious of petty theft, especially in crowded areas and on beaches. Common scams include overcharging by taxis or ride services and timeshare presentations that pressure visitors into high-cost deals. It's advisable to use official transportation options, keep valuables secure, and remain aware of surroundings to ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Florence, SC to Fort Myers, FL

Most Florence, SC to Fort Myers, FL trains use the Florence Station to Fort Myers, McDowell Dr (Love's Travel Stop) station pair. Use this guide to compare Florence, SC and Fort Myers, FL train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Florence
Arrival train stations in Fort Myers

Which Florence, SC station do trains to Fort Myers, FL leave from?

Trains from Florence, SC to Fort Myers, FL leave from Florence Station. The station is 0 miles (1 km) from Florence, SC city centre at 805 East Day Street, Florence, SC 29506, USA.
Florence Station805 East Day Street, Florence, SC 29506, USA+1 800-872-7245LockersParkingDiningTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeInformation DeskLuggage Carts
City-centre transport

Getting to Florence Station from Florence city centre

BusGreyhound services available nearby

Florence Station train station facilities and services

Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.

Food and drink

Food and drink options are available at Florence Station.

Tickets and information

Ticket office support is available at Florence Station. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at Florence Station. Lost and found is available at the station.

Parking, taxis and toilets

Available at Florence Station: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Florence Station: Elevators, ramps.

Shops, hotels and contact

Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.

More options for your journey from Florence, SC to Fort Myers, FL

Here are some other resources that might have the information you need

HomeTrainsTrains in USATrain Times to Fort Myers, FLFlorence, SC to Fort Myers, FL train

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