- Must visit
Edison and Ford Winter Estates Museum
Major local museum at the Edison and Ford estates with inventions, automobiles, and exhibits on two influential American innovators.
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Travel Information
Compare bus for Florence, SC to Fort Myers, FL
Omio recommends booking the bus as it is the most popular option from Florence, SC to Fort Myers, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €113 For those with little time, consider booking a bus, which has an average total journey time of 20h 24m. Average ticket prices depend on the travel mode: a bus costs an average of €113, while a bus costs an average of €113.
Distance: 537 miles (865 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
€113 Average price Cheapest | €101 Average price (fuel + tolls) |
20h 24m Average total duration Fastest 19h 54m Onboard + 30m Additional time* | 9h 11m Average total duration (door-to-door) |
 Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
The cheapest way to travel from Florence, SC to Fort Myers, FL is a bus with an average price of €113.
The fastest way to travel from Florence, SC to Fort Myers, FL is by bus with an average journey time of 19h 54m.
Yes, you can take a bus between Florence, SC and Fort Myers, FL.
We recommend using the bus as it is the most popular way to get from Florence, SC to Fort Myers, FL among Omio's users.
Compare prices and tickets Florence, SC to Fort Myers, FL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Florence, SC to Fort Myers, FL
USAUSA
Take a train from Florence, SC to Fort Myers, FL and enjoy the approximately 537 miles (865 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 07:00, the last at 07:00.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €66
Distance 537 miles (865 km) |
First train 7:00 AM |
Last train 7:00 AM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 4 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €66
Complete guide to Fort Myers, FL
Things to do in Fort Myers, FL
Discover the best of Fort Myers, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Fort Myers, FL trip today.
- Recommended
IMAG History & Science Center
Excellent regional history museum covering Southwest Florida's people, places, and development through engaging permanent exhibitions.
- Recommended
IMAG Science Exhibits
Interactive science museum with aquariums, live animals, and hands-on exhibits that make it especially strong for families and curious adults.
- Must visit
Fort Myers River District
Walkable historic downtown filled with shops, galleries, event spaces, and river views, making it the city's main strolling district.
- Must visit
Six Mile Cypress Slough Preserve
Large urban nature preserve with boardwalks, trails, and birding, offering a wild contrast to the built-up city center.
- Recommended
First Street
Palm-lined downtown street known for preserved architecture, boutiques, murals, and an easy introduction to the city's historic core.
- Gluten-free
Gulf Pink Shrimp
Fresh Gulf shrimp, often peeled and eaten chilled or quickly sautéed. A Southwest Florida staple thanks to nearby shrimping waters and seafood culture.
Grouper Sandwich
A Florida classic of flaky local fish, usually grouper, served blackened, grilled, or fried in a sandwich. Popular along Fort Myers waterfronts.
- Gluten-free
Stone Crab Claws
Cracked Florida stone crab claws served chilled with mustard sauce. A prized seasonal seafood known across coastal South Florida and the Gulf.
The Veranda
Established fine dining restaurant serving refined seafood and steaks in an elegant historic downtown setting.
Doc Ford's Rum Bar & Grille
Casual waterfront seafood spot known for fresh local shrimp, grouper, and island atmosphere near the marina.
Bennett's Fresh Roast
Beloved local Cuban cafe offering pressed sandwiches, coffee, pastries, and traditional Latin comfort food in a casual setting.
US Dollar ($)
Moderate for Florida beach travel. Hotels and dining run mid-range, while car travel and parking add costs. Cheaper than Miami, but pricier than many inland US cities.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $50+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 per drink or coffee in cafes and bars.
FAQs: Trains from Florence, SC to Fort Myers, FL
Find answers to the most common questions about traveling from Florence, SC to Fort Myers, FL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.
The distance by train from Florence, SC to Fort Myers, FL is 537 miles (865 km).
The first train from Florence, SC to Fort Myers, FL leaves at 7:00 AM.
The last train from Florence, SC to Fort Myers, FL leaves at 7:00 AM.
Unfortunately, there is no night train available from Florence, SC to Fort Myers, FL.
The cheapest way to get from Florence, SC to Fort Myers, FL is by bus, with a cost of around €66.
The train journey from Florence, SC to Fort Myers, FL offers a blend of urban and rural landscapes, passing through charming Southern towns and offering views of the Carolinas’ lush greenery and some coastal areas, though it may not be traditionally considered one of the most scenic routes in the U.S.
For a well-rounded experience in Fort Myers, FL, three to four days are recommended to explore its beautiful beaches, visit the Edison and Ford Winter Estates, and enjoy local dining and shopping options.
No, you cannot take the train from Florence, SC to Fort Myers, FL.
Since neither Florence, SC nor Fort Myers, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Florence, SC to Fort Myers, FL among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Fort Myers, FL, travelers should be cautious of petty theft, especially in crowded areas and on beaches. Common scams include overcharging by taxis or ride services and timeshare presentations that pressure visitors into high-cost deals. It's advisable to use official transportation options, keep valuables secure, and remain aware of surroundings to ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
Most popular train connections from Florence, SC
More options for your journey from Florence, SC to Fort Myers, FL
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Most popular trains to and from Fort Myers, FL and Florence, SC
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