The cheapest and fastest trains from Florence, SC to Lancaster, PA
Cheapest price
$171
Average price
$171
Fastest journey
13 h 37 m
Average duration
13 h 37 m
Trains per day
1
Distance
718 km
The best way to find a cheap train ticket from Florence, SC to Lancaster, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Lancaster, PA will cost around $171 if you buy it on the day, but the cheapest tickets can be found for only $171.
Of the 1 trains that leave Florence, SC for Lancaster, PA on Tue, Mar 24, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 24 the direct trains cover the 718 km distance in an average of 13 h 37 m but if you time it right, some trains will get you there in just 13 h 37 m .
On Tue, Mar 24 the slowest trains will take 13 h 37 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Compare prices and tickets Florence, SC to Lancaster, PA by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Mar 29
Journey information
Overview: Train from Florence, SC to Lancaster, PA
Trains from Florence, SC to Lancaster, PA run on average 2 times per day, taking around 11h 28m. Cheap train tickets for this journey start at $171 (€138) if you book in advance.
The earliest train runs at 05:35, the last at 13:45. The fastest train covers the 446 miles (718 km) distance in 12h 36m.
Distance 446 miles (718 km) |
Average train duration 11h 28m |
Cheapest ticket price $171 (€138) |
Trains per day 2 |
Fastest train 12h 36m |
First train 05:35 |
Last train 13:45 |
Train companies: Amtrak from Florence, SC to Lancaster, PA trainsAmtrak trains will get you between Florence, SC and Lancaster, PA from $171 (€138). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Florence, SC to Lancaster, PA
Find answers to the most common questions about traveling from Florence, SC to Lancaster, PA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lancaster, PA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence, SC to Lancaster, PA
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Elevators, ramps.
- Aloft Florence
- Hyatt Place Florence Downtown
- Hotel Florence, Tapestry Collection by Hilton
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Greyhound services available nearby
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Elevators, ramps.
- Lancaster Marriott at Penn Square
- The Hotel Lancaster
- Cork Factory Hotel
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Red Rose Transit Authority (RRTA) services available
Most popular train connections from Florence, SC
More options for your journey from Florence, SC to Lancaster, PA
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