The cheapest and fastest trains from Florence, SC to Lancaster, PA
Cheapest price
$173
Average price
$173
Fastest journey
15 h 18 m
Average duration
15 h 18 m
Trains per day
1
Distance
718 km
The best way to find a cheap train ticket from Florence, SC to Lancaster, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Lancaster, PA will cost around $173 if you buy it on the day, but the cheapest tickets can be found for only $173.
Of the 1 trains that leave Florence, SC for Lancaster, PA on Sat, Jun 27, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 27 the direct trains cover the 718 km distance in an average of 15 h 18 m but if you time it right, some trains will get you there in just 15 h 18 m .
On Sat, Jun 27 the slowest trains will take 15 h 18 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3:32 AM15h18Florence, SC6:50 PMLancaster, PA$1731One-way0 transfers
3:32 AM15h18Florence, SC6:50 PMLancaster, PA$1731One-way0 transfers
Travel Information
Compare train for Florence, SC to Lancaster, PA
Omio recommends booking the train as it is the most popular option from Florence, SC to Lancaster, PA among Omio's users. If you are prioritising price take the train with prices starting from $169. For those with little time consider booking a train which can get you there in 11h 36m. The ticket price range depends on the travel mode: a train costs an average of $169, and a train costs an average of $169.
Distance: 446 miles (718 km)
Compare train with
Most popular Train | Driving |
|---|---|
$186 Average price Cheapest | $102 Average price (fuel + tolls) |
12h 6m Average total duration Fastest 11h 36m Onboard + 30m Additional time* | 8h 10m Average total duration (door-to-door) |
![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options |
Tickets start at around $186 (€152) compared to roughly $102 (€83) in fuel and tolls — a saving of about $-83.79 (€-68.55). The journey takes 11h 36m versus 8h 10m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Florence, SC to Lancaster, PA train times
The table below shows live departures for Florence, SC to Lancaster, PA trains for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:32 AM Florence, SC | 15h18 | 6:50 PM Lancaster, PA | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Lancaster, PA by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 21
Jun 22
Jun 23
Jun 24
Jun 25
Jun 26
Jun 27
Journey information
Overview: Train from Florence, SC to Lancaster, PA
Trains from Florence, SC to Lancaster, PA run on average 2 times per day, taking around 11h 36m. Cheap train tickets for this journey start at $169 (€138) if you book in advance.
The earliest train runs at 05:35, the last at 13:45. The fastest train covers the 446 miles (718 km) distance in 13h 37m.
Distance 446 miles (718 km) |
Average train duration 11h 36m |
Cheapest ticket price $169 (€138) |
Trains per day 2 |
Fastest train 13h 37m |
First train 5:35 AM |
Last train 1:45 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
Train companies: Amtrak from Florence, SC to Lancaster, PA trainsAmtrak trains will get you between Florence, SC and Lancaster, PA from $169 (€138). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Florence, SC to Lancaster, PA
Find answers to the most common questions about traveling from Florence, SC to Lancaster, PA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lancaster, PA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence, SC to Lancaster, PA
Most Florence, SC to Lancaster, PA trains use the Florence Station to Lancaster Station station pair. Use this guide to compare Florence, SC and Lancaster, PA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Which Florence, SC station do trains to Lancaster, PA leave from?
Getting to Florence Station from Florence city centre
Florence Station train station facilities and services
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink
Food and drink options are available at Florence Station.
Tickets and information
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Florence Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Florence Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence Station: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
Which Lancaster, PA station do trains from Florence, SC arrive at?
Getting to Lancaster Station from Lancaster city centre
Lancaster Station is 1 km from Lancaster city centre. Public transport options include:
Lancaster Station train station facilities and services
Lancaster Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Rental, Information Desk, and Luggage Carts.
Food and drink
Food and drink options are available at Lancaster Station.
Tickets and information
Ticket office support is available at Lancaster Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Lancaster Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Lancaster Station: Parking, Taxis, WC.
Bike and car services
Available at Lancaster Station: Bike Rental.
Accessibility
Accessibility facilities are available at Lancaster Station: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Lancaster Marriott at Penn Square, The Hotel Lancaster, Cork Factory Hotel.
Most popular train connections from Florence, SC
More options for your journey from Florence, SC to Lancaster, PA
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