- Must visit
Museo del Canal Interoceánico de Panamá
Museum in a former convent in Casco Antiguo presenting pre-Columbian, colonial, and modern artifacts for a concise overview of Panama's history.
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The cheapest and fastest flights from Mexico City to Panama City
Showing times, prices and bookable tickets for Nov 10
- Cheapest price on Nov 10
- €594
- Average ticket price on Nov 10
- €864
- Fastest journey on Nov 10
- 3 h 44 m
- Average journey duration on Nov 10
- 3 h 48 m
- Flights on Nov 10
- 53
- Distance
- 2408 km
Cheap tickets
The best way to find a cheap flight ticket from Mexico City to Panama City is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mexico City to Panama City will cost around €864 if you buy it on the day, but the cheapest tickets can be found for only €594.
Fast flights
On Tue, Nov 10, we found 53 flights from Mexico City to Panama City, including 7 direct services.
On Tue, Nov 10 the direct flights cover the 2408 km distance in an average of 3 h 48 m but if you time it right, some flights will get you there in just 3 h 44 m .
On Tue, Nov 10 the longest flights will take 3 h 52 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
CM1955:55 AM 3h52 Mexico City 10:47 AM Panama City €594 1 One-way 0 transfers- CM536
3:25 AM 3h46 Mexico City 8:11 AM Panama City €594 1 One-way 0 transfers 
AV187 · AV5812:30 AM 7h40 Mexico City 9:10 AM Panama City €654 1 One-way 1 transfer- AV187 · AV56
12:30 AM 13h45 Mexico City 3:15 PM Panama City €654 1 One-way 1 transfer - AV187 · AV60
12:30 AM 15h45 Mexico City 5:15 PM Panama City €654 1 One-way 1 transfer
- CM149
1:20 AM 3h44 Mexico City 6:04 AM Panama City €920 1 One-way 0 transfers - CM536
3:25 AM 3h46 Mexico City 8:11 AM Panama City €594 1 One-way 0 transfers - CM135
3:30 PM 3h48 Mexico City 8:18 PM Panama City €920 1 One-way 0 transfers - CM121
1:10 PM 3h49 Mexico City 5:59 PM Panama City €920 1 One-way 0 transfers - CM195
5:55 AM 3h52 Mexico City 10:47 AM Panama City €594 1 One-way 0 transfers
Journey information
Overview: Mexico City to Panama City flight
Mexico
Panama
Flights from Mexico City to Panama City depart on average 34 times per day, taking around 6h 10m. Cheap flight tickets for this journey start at €108 if you book in advance.
There are 7 flights per day. The earliest flight runs at 00:40, the last at 23:20. The fastest flight covers the 1496 miles (2408 km) distance in 3h 40m. June is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1496 miles (2408 km) |
Average flight duration 6h 10m |
Cheapest ticket price €108 |
Flights per day 34 |
Direct flights 7 |
Fastest flight 3h 40m |
First flight 12:40 AM |
Last flight 11:20 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Mexico City to Panama City trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Mexico City to Panama City.
Cheap plane tickets from Mexico City to Panama City can start from as little as €108 when you book in advance. The average flight ticket price for Mexico City to Panama City is €416 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest flight from Mexico City to Panama City leaves at 12:40 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Mexico City to Panama City leaves at 11:20 PM.
Yes, there are 7 direct flights a day from Mexico City to Panama City with Aeromexico, COPA Airlines. Schedules can vary on holidays or weekends with fewer direct flights.
Live departures
Mexico City to Panama City flight times
The table below shows live departures for Mexico City to Panama City flights for today, Monday, November 9. You can also manually refresh the results below to see updated flight journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 7:20 AM Mexico City | 3h36 | 10:56 AM Panama City | 0 transfersDirect | |
| 7:50 PM Mexico City | 18h00 | 1:50 PM Panama City | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Why should you book Mexico City to Panama City flights with Omio?
Avianca as well as Aeromexico, COPA Airlines, American Airlines and more offer flights services from Mexico City to Panama City.
Omio is an official ticket reseller for all your travel options from Mexico City to Panama City.
Why book with Omio vs Avianca?
- Compare with other providers: On Omio, you can not only buy tickets for Avianca, but also compare tickets for the likes of Aeromexico, COPA Airlines or American Airlines to find the best option for your trip from Mexico City to Panama City.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Trip, Kayak or Edreams?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Aeromexico, COPA Airlines or American Airlines to find the best option for your trip from Mexico City to Panama City.
Airlines: Avianca, COPA Airlines, American Airlines, Aeromexico from Mexico City to Panama CityFind the best flights between Mexico City to Panama City with Omio's travel partners Avianca, COPA Airlines, American Airlines, Aeromexico from €108. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Avianca
About
Avianca is the national and largest airline of Colombia, and one of the oldest airlines in the world, tracing its origins back to 1919. It serves as the flagship of a group of airlines across the Americas, operating under a codesharing system. Avianca boasts an extensive network of destinations throughout the Americas, with its main hub located at El Dorado International Airport in Bogotá. The airline is a member of the Star Alliance, offering various classes of service from economy to business and first-class. Its fleet includes modern aircraft such as the Airbus A320 family, Airbus A330, and Boeing 787 Dreamliner.
Luggage & cancellation policy
Average Avianca Duration
4h 5m
Cheapest Avianca Price
€197
Avianca frequency
22 a day
Luggage included
1 carry-on bag (10kg) and 1 personal item included in most fares
Additional luggage
Additional checked baggage can be purchased, up to 32kg per piece
Cancellation Policy
Refunds available depending on fare type, some tickets non-refundable. Changes permitted with fee.
Pregnant on board
Pregnant women can travel up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-17 can travel as unaccompanied minors with additional service fee. Must be booked at least 48 hours in advance
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested 48h before flight
Pets
Small pets in cabin, max 8kg including carrier
Entertaiment on board
COPA Airlines
About
Copa Airlines, Panama's flag carrier, was founded in 1947 and is headquartered in Panama City with its main hub at Tocumen International Airport. The airline operates as a full-service carrier, connecting North, Central, and South America, as well as the Caribbean. As a member of the Star Alliance, Copa Airlines serves over 80 destinations in more than 30 countries. The airline's fleet primarily consists of Boeing 737 aircraft, with some Embraer 190s for regional flights. Copa Airlines is recognized for its punctuality and its strategic "Hub of the Americas" at Tocumen, which consolidates passenger traffic for efficient service.
Luggage & cancellation policy
Average COPA Airlines Duration
3h 40m
Cheapest COPA Airlines Price
€108
COPA Airlines frequency
7 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item
Additional luggage
Additional checked bags can be purchased, fees vary by route
Cancellation Policy
Refundable tickets available for full refund, non-refundable tickets can be changed for fee
Pregnant on board
Up to 36 weeks for single pregnancy, 32 weeks for multiple. Medical certificate required after 28 weeks
Unaccompagned minor
Ages 5-11 must use Unaccompanied Minor service. Ages 12-17 optional. Service fee applies
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
Wheelchair assistance available with 48-hour advance notice
Pets
Small pets in cabin, must be in approved carrier under seat
Entertaiment on board
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average American Airlines Duration
6h 28m
Cheapest American Airlines Price
€697
American Airlines frequency
25 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board
Aeromexico
About
Aeromexico, Mexico's flag carrier, was established in 1934 as Aeronaves de México. It operates over 600 daily flights from its main hub at Mexico City International Airport to 89 cities across three continents, including destinations in Mexico, the United States, Latin America, Europe, Canada, and Asia. As a founding member of the SkyTeam airline alliance, Aeromexico partners with 20 airlines, offering access to over 1,000 destinations in 177 countries. The airline's fleet includes Boeing 787 and 737 jet airliners, and Embraer 190 models.
Luggage & cancellation policy
Average Aeromexico Duration
3h 45m
Cheapest Aeromexico Price
€109
Aeromexico frequency
1 a day
Luggage included
1 carry-on bag (21.5 x 15.7 x 10 inches) and 1 personal item included
Additional luggage
Additional checked baggage can be purchased, fees vary by route and fare class
Cancellation Policy
Refunds available depending on fare type, most restrictive basic fares are non-refundable
Pregnant on board
Pregnant passengers can travel up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required after 28 weeks
Unaccompagned minor
Unaccompanied minor service available for children 5-17 years, mandatory for 5-11 years, fees apply
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Aeromexico provides wheelchair assistance and special services for passengers with disabilities, must be requested 48h in advance
Pets
Small pets in cabin allowed, must be in carrier under seat, max weight 20lbs including carrier
Entertaiment on board
Companies, tickets, and onboard amenities between Mexico City and Panama City
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a flight from Mexico City to Panama City, you can count on Avianca, Aeromexico, COPA Airlines, American Airlines for the best way to get you to Panama City. You can also check all possible airlines who offer a service between Mexico City and Panama City and compare the amenities they offer before buying a plane ticket.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
Complete guide to Panama City
Things to do in Panama City
Discover the best of Panama City — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Panama City trip today.
- Must visit
Biomuseo
Modern museum by Frank Gehry exploring biodiversity, geology, and regional ecosystems through interactive exhibits on the Amador Causeway.
- Recommended
Museo de Arte Contemporáneo de Panamá
Contemporary art museum in Ancón with rotating exhibitions by Panamanian and international artists, plus a sculpture garden and canal views nearby.
- Must visit
Casco Antiguo
Atmospheric old quarter of plazas, churches, rooftops, and restored streets. Ideal for walking, architecture, and sunset views over the bay.
- Must visit
Cinta Costera
Long waterfront promenade popular for walking, cycling, skyline views, and breezes. A classic urban outing linking neighborhoods along the bay.
- Must visit
Amador Causeway
Scenic causeway built with canal excavation rock, known for bay views, marinas, bike rides, and easy access to museums and the cruise terminal area.
- Gluten-free
Tamal De Olla
Corn dough stuffed with meat, wrapped in banana leaves and boiled. A festive Panamanian staple with strong Afro-Caribbean and rural traditions.
- Gluten-free
Sancocho Panameño
Shredded chicken and rice soup thickened with vegetables and herbs. A comforting national favorite often served at family meals and celebrations.
- Gluten-free
Carimañola
Fried corn dough topped with stewed beef or chicken. A beloved street snack and breakfast item rooted in Panama’s corn-based cooking.
Donde José
Upscale dining in Casco Viejo focused on refined Panamanian ingredients and contemporary local cuisine in an elegant setting.
El Trapiche
Traditional Panamanian restaurant serving local classics in a casual setting, popular for breakfast, soups, and home-style dishes.
Mercado De Mariscos
Historic seafood market complex known for fresh ceviche and casual local seafood counters with lively daytime atmosphere.
Panamanian balboa (B/.) and US dollar ($)
Moderate for the region: hotels and dining cost more than many Central American capitals, but local transit and casual meals stay fairly affordable for tourists.
Average meal costs
- Budget
- B/.5-B/.10 for fast food or local eateries.
- Mid-range
- B/.15-B/.30 per person for a meal.
- Fine dining
- B/.35+ per person for upscale restaurants.
- Coffee
- B/.2-B/.4 for coffee or cappuccino.
Tipping culture
Service may be included. If not, tip 10% in restaurants. Round up or add a little for taxis. Small tips are appreciated in cafes.
MiBus Maps Panamá
Get the appOfficial public transport app
Prices
- Single ticket
- B/. 0.35
- Day pass
- null
To the city center
Aeropuerto Station -> Albrook, Panama City
- Distance
- 24 km
- Travel time
- 35 min
- Use a reloadable transit card for Metro and MiBus. MiBus states bus fares are B/. 0.25 on trunk routes and B/. 0.75 on corredor services, while Metro regular fare is B/. 0.35.
- Airport access is by Metro Line 2 via Aeropuerto Station. The official Metro network map shows Aeropuerto on Line 2 for trips toward Panama City.
Plan your visit to Panama City
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Panama City.
Panama uses the Balboa (PAB) alongside the US Dollar (USD), which is widely accepted. For travelers, using cards is convenient in cities and tourist areas, but carrying some cash is recommended for smaller vendors and rural locations.
In Panama City, travelers should be cautious of petty theft, especially pickpocketing and bag snatching in crowded areas like Casco Viejo and public transportation. Avoid flashing valuables and be vigilant at ATMs to prevent card skimming. Scams involving unofficial taxi drivers overcharging or taking longer routes are common, so using authorized taxi services or ride-hailing apps is recommended. Additionally, travelers should stay aware of their surroundings at night and avoid poorly lit or isolated areas to ensure personal safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Mexico City to Panama City Flight
Find answers to the most common questions about traveling from Mexico City to Panama City by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Panama City, this guide helps you travel smarter and with confidence.
Yes, you can take a flight between Mexico City and Panama City.
popular airports
Popular airports from Mexico City to Panama City
Most Mexico City to Panama City flights use the Mexico City to Panama City airport pair. Use this guide to compare Mexico City and Panama City airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Departure airports in Mexico City
Arrival airports in Panama City
Which Mexico City airport do flights to Panama City leave from?
Flights from Mexico City to Panama City depart from Mexico City. The airport is 3 miles (5 km) from Mexico City city centre at Av. Capitán Carlos León s/n, Peñón de los Baños, Venustiano Carranza, 15620 Ciudad de México, CDMX, Mexico.
Mexico City (MEX)Av. Capitán Carlos León s/n, Peñón de los Baños, Venustiano Carranza, 15620 Ciudad de México, CDMX, Mexico
City-centre transport
Getting to Mexico City from Mexico City city centre
Mexico City is 4 km from Mexico City city centre. Public transport options include:
Metro Line 5, terminal Aérea, 8 km
Mexico City airport facilities and services
Mexico City has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants are located in both terminals, offering Mexican and intertiol cuisines. Top options include Toks and Wings.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located throughout the airport, near entrances and exits.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Mexico City: Parking, Taxis, WC.
Bike and car services
Available at Mexico City: Car Rental.
Accessibility
Accessibility facilities are available at Mexico City: Elevators, ramps, assistance.
Shops, hotels and contact
Nearby hotels include Hotels such as Hilton Mexico City Airport are located within the airport and others like Courtyard by Marriott within walking distance..
Toluca International Airport (TLC)Lic. Adolfo López Mateos International Airport, San Pedro Totoltepec, 50226 Toluca de Lerdo, Méx., Mexico
City-centre transport
Getting to Toluca International Airport from Mexico City city centre
Toluca International Airport is 11 km from Mexico City city centre. Public transport options include:
Train1h 26m · €6 · every ~50 min
Bus1h 16m · €6 · every ~8 min
Estrella · 3h 9m · €1 · every ~26 min
Shuttle1h 0m · €9 · every ~1 min
Toluca International Airport airport facilities and services
Toluca International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options available inside terminal.
Wi-Fi and ATMs
WiFi available throughout the airport. ATMs are aTMs available near check-in areas.
Tickets and information
Ticket office support is available at Toluca International Airport.
Parking, taxis and toilets
Available at Toluca International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Toluca International Airport: Facilities are accessible to disabled passengers.
Which Panama City airport do flights from Mexico City arrive at?
Flights from Mexico City to Panama City arrive at Panama City. Panama City is 1 miles (2 km) from Panama City city centre.
Panama City (PTY)Tocumen Intertiol Airport, Avenida Domingo Díaz, Pama City, Pama
City-centre transport
Getting to Panama City from Panama City city centre
Panama City is 1 km from Panama City city centre. Public transport options include:
Metro Line 2, Estación Corredor Sur, 24 km
Panama City airport facilities and services
Panama City has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Various restaurants in food court, including local cuisine and fast food
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in all terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Panama City: Parking, Taxis, WC.
Bike and car services
Available at Panama City: Car Rental.
Accessibility
Accessibility facilities are available at Panama City: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels nearby, such as Crowne Plaza Pama Airport..
Airports for flights from Mexico City to Panama City
See which airports are used for flights between Mexico City and Panama City, including airport details.
Flights from Mexico City to Panama City generally leave from Mexico City and arrive in Panama City.Mexico City is 3 miles (5 km) away from Mexico City city centre and Panama City is 1 miles (2 km) from Panama City city centre.
More options for your journey from Mexico City to Panama City
Here are some other resources that might have the information you need
Most popular flights to and from Panama City and Mexico City
Most popular flights to Panama City
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