Greenville, SC GSP to Indianapolis, IN IND Flights

Sun, May 31
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Journey information

Overview: Greenville, SC to Indianapolis, IN flight

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Flights from Greenville, SC to Indianapolis, IN depart on average 5 times per day, taking around 7h 22m. Cheap flight tickets for this journey start at $169 (€136) but you can travel from only $111 (€90) by bus.

The earliest flight runs at 05:10, the last at 20:21. The fastest flight covers the 397 miles (640 km) distance in 7h 22m. June is the cheapest month to fly.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $111 (€90)
Distance
397 miles (640 km)
Average flight duration
7h 22m
Cheapest ticket price
$169 (€136)
Flights per day
5
Fastest flight
7h 22m
First flight
5:10 AM
Last flight
8:21 PM
Cheapest Month
Jun
Cheapest Day
Fri
High Season
Apr - Jun
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $111 (€90)

Travel Information

Compare bus, train, and flight for Greenville, SC to Indianapolis, IN

Omio recommends booking the train as it is the most popular option from Greenville, SC to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $111. For those with little time consider booking a flight which can get you there in 7h 22m. The ticket price range depends on the travel mode: a bus costs an average of $111, and a train costs an average of $169.

Distance: 397 miles (640 km)

Compare flight with

Flight
Most popular
Train
Bus
Driving

$169

Average price

$169

Average price

$111

Average price

Cheapest

$101

Average price

(fuel + tolls)

10h 22m

Average total duration

Fastest

7h 22m

Onboard

+

3h 0m

Additional time*

28h 2m

Average total duration

27h 32m

Onboard

+

30m

Additional time*

15h 55m

Average total duration

15h 25m

Onboard

+

30m

Additional time*

8h 12m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Greenville, SC to Indianapolis, IN is a bus with an average price of $111 (€90).

This is compared to other travel options from Greenville, SC to Indianapolis, IN:

A bus is $58 (€46) less than a flight for this route with tickets for a flight from Greenville, SC to Indianapolis, IN costing on average $169 (€136).

A bus is $58 (€47) less than a train for this route with tickets for a train from Greenville, SC to Indianapolis, IN costing on average $169 (€136).

The fastest way to travel from Greenville, SC to Indianapolis, IN is by flight with an average journey time of 7h 22m.

Other travel options to Indianapolis, IN take longer:

Bus takes on average 15h 25m.

Train takes on average 27h 32m.

It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Indianapolis, IN including taking a bus, train, and flight.

Compare prices and tickets Greenville, SC to Indianapolis, IN by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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May 31
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Complete guide to Indianapolis

Things to do in Indianapolis

Discover the best of Indianapolis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis trip today.

  • Must visit

The Children's Museum of Indianapolis

The world's largest children's museum, known for immersive science, history, and culture exhibits for all ages.

  • Must visit

Newfields

A major art campus featuring the Indianapolis Museum of Art, gardens, and rotating exhibitions in a scenic setting.

  • Must visit

Indianapolis Motor Speedway Museum

A must for racing fans, with historic cars, Indianapolis 500 artifacts, and motorsport heritage.

United States Dollar

Moderate by U.S. city standards. Hotels vary by events, while casual dining, coffee, and transport are generally manageable.

Average meal costs

Budget
USD 10-15 for fast food or a simple lunch.
Mid-range
USD 20-35 per person at a mid-range restaurant.
Fine dining
USD 60+ per person before drinks and tax.
Coffee
USD 3-6 for drip coffee or a latte.

Tipping culture

Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for casual services.

FAQs: Greenville, SC to Indianapolis, IN Flight

Find answers to the most common questions about traveling from Greenville, SC to Indianapolis, IN by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
Cheap plane tickets from Greenville, SC to Indianapolis, IN can start from as little as $169 (€136) when you book in advance. The average flight ticket price for Greenville, SC to Indianapolis, IN is $169 (€136) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Greenville, SC to Indianapolis, IN is 7h 22m to travel the 397 miles (640 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Greenville, SC to Indianapolis, IN leaves at 5:10 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Greenville, SC to Indianapolis, IN leaves at 8:21 PM.
The cheapest month for a flight from Greenville, SC to Indianapolis, IN is June.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Indianapolis, IN including taking a bus, train, and flight.
Since neither Greenville, SC nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is no time difference between Greenville, SC and Indianapolis, IN.
The best events to attend in Indianapolis, IN include:
  • Indy 500, the iconic automobile race held annually on Memorial Day weekend, attracting racing fans from around the world
  • Indiana State Fair, a beloved summer tradition featuring agricultural exhibits, live entertainment, and delicious local food
  • Gen Con, one of the largest tabletop gaming conventions in North America, offering a vibrant atmosphere for gamers and enthusiasts alike.
Some of the most interesting sights to explore in Indianapolis, IN are:
  • Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
  • The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
  • Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
  • Indiana State Museum, showcasing the state's history, art, and science through various exhibits
  • White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best holidays to experience in Indianapolis, IN include:
  • Independence Day, vibrant fireworks and festive parades celebrating American heritage
  • Labor Day, pleasant weather perfect for outdoor activities and local events
  • Thanksgiving, a time for family gatherings with a cozy atmosphere and fewer crowds.
The best things to do in Indianapolis, IN include:
  • Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
  • Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
  • Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
  • Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
  • Enjoy a walk along the canal and cultural attractions at White River State Park.
The best season to visit Indianapolis, IN is Spring or Fall. The best weather to explore Indianapolis, IN is during April-May or September-October.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular airports

Popular airports from Greenville, SC to Indianapolis, IN

Greenville
Indianapolis
The major airport for departures in Greenville is Greenville-Spartanburg International Airport. Find all the information you need to know about services, amenities and connections at Greenville-Spartanburg International Airport for your trip from Greenville to Indianapolis.
Greenville-Spartanburg International Airport (GSP)
information

Most popular flights from Greenville, SC

More options for your journey from Greenville, SC to Indianapolis, IN

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