Journey information
Overview: Greenville, SC to Portland, ME flight
Flights from Greenville, SC to Portland, ME depart on average 20 times per day, taking around 6h 5m. Cheap flight tickets for this journey start at $506 (€410) but you can travel from only $269 (€218) by bus.
The earliest flight runs at 05:20, the last at 19:56. The fastest flight covers the 888 miles (1430 km) distance in 4h 5m. April is the cheapest month to fly.
Distance 888 miles (1430 km) |
Average flight duration 6h 5m |
Cheapest ticket price $506 (€410) |
Flights per day 20 |
Fastest flight 4h 5m |
Cheapest month April |
First flight 05:20 |
Last flight 19:56 |
The cheapest and fastest flights from Greenville, SC to Portland, ME
Cheapest price
$506
Average price
$506
Fastest journey
4 h 5 m
Average duration
4 h 5 m
Flights per day
1
Distance
1430 km
The best way to find a cheap flight ticket from Greenville, SC to Portland, ME is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Portland, ME will cost around $506 if you buy it on the day, but the cheapest tickets can be found for only $506.
Of the 1 flights that leave Greenville, SC for Portland, ME onMon, Mar 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 23 the direct flights cover the 1430 km distance in an average of 4 h 5 m but if you time it right, some flights will get you there in just 4 h 5 m .
On Mon, Mar 23 the longest flights will take 4 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Greenville, SC to Portland, ME
Omio recommends booking the flight as it is the most popular option from Greenville, SC to Portland, ME among Omio's users. If you are prioritising price take the bus with prices starting from $269. For those with little time consider booking a flight which can get you there in 6h 5m. The ticket price range depends on the travel mode: a bus costs an average of $269, and a flight costs an average of $506.
Distance: 888 miles (1430 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
$513 Average price | $270 Average price Cheapest |
9h 5m Average total duration Fastest 6h 5m Onboard + 3h 0m Additional time* | 42h 5m Average total duration 41h 35m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Greenville, SC to Portland, ME by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Greenville, SC to Portland, ME Flight
Find answers to the most common questions about traveling from Greenville, SC to Portland, ME by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Portland, ME, this guide helps you travel smarter and with confidence.

- Portland Rose Festival, a vibrant celebration of roses featuring parades, carnival rides, and cultural events
- Portland International Beer Fest, a lively festival showcasing craft beers from around the world with tastings and food pairings
- Waterfront Blues Festival, an annual music event featuring top blues artists and benefiting local charities.
- Independence Day, vibrant fireworks and festive celebrations throughout the city
- Labor Day, pleasant weather perfect for outdoor activities and local events
- Thanksgiving, a time for family gatherings with a cozy atmosphere and fewer crowds.
popular airports
Popular airports from Greenville, SC to Portland, ME
- Free Wi-Fi available throughout the airport.
- Shops include Paradies Lagardère and Hudson News in the terminal.
- Parking available near terminals, approximately 0.47€ ($0.50) per hour.
- Restaurants available include Linda Bean's Lobster Cafe and Starbucks in the terminal.
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Lounge access available for Delta Sky Club members.
- Lost and Found located in the main terminal.
- Car rental services are available from companies like Avis, Budget, and Hertz on-site.
- Bus Route 5, Portland Transportation Center, 3 miles
Most popular flights from Greenville, SC
More options for your journey from Greenville, SC to Portland, ME
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