- Must visit
National Museum
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
Cheapest price
$94
Average price
$133
Fastest journey
1 d 13 h 25 m
Average duration
1 d 19 h 15 m
Buses per day
2
Distance
1255 km
The best way to find a cheap bus ticket from Thessaloniki International Airport to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Thessaloniki International Airport to Prague will cost around $133 if you buy it on the day, but the cheapest tickets can be found for only $94.
Of the 2 buses that leave Thessaloniki International Airport for Prague on Fri, Jul 10, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 10 the direct buses cover the 1255 km distance in an average of 1 d 19 h 15 m but if you time it right, some buses will get you there in just 1 d 13 h 25 m .
On Fri, Jul 10 the slowest buses will take 2 d 1 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the flight as it is the most popular option from Thessaloniki International Airport to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $94. For those with little time consider booking a flight which can get you there in 3h 30m. The ticket price range depends on the travel mode: a bus costs an average of $94, and a flight costs an average of $164.
Distance: 779 miles (1255 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$145 Average price Cheapest | $236 Average price | $341 Average price (fuel + tolls) |
46h 30m Average total duration 46h 0m Onboard + 30m Additional time* | 6h 30m Average total duration Fastest 3h 30m Onboard + 3h 0m Additional time* | 15h 47m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Thessaloniki International Airport to Prague:
A bus is $91 (€75) less than a flight for this route with tickets for a flight from Thessaloniki International Airport to Prague costing on average $236 (€194).
Other travel options to Prague take longer:
Bus takes on average 46h 0m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:20AM | Arrival Time 06:45PM | Duration 37h25 | Departure days Fri | Cheapest price $172 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 06:00PM | Duration 51h30 | Departure days Sat | Cheapest price $168 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 04:35PM | Duration 49h05 | Departure days Fri | Cheapest price $94 |
The table below shows live departures for Thessaloniki International Airport to Prague buses for tomorrow, Friday, July 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:20 AM Thessaloniki International Airport | 37h25 | 6:45 PM Prague | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare flight and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Thessaloniki International Airport to Prague run on average 4 times per day, taking around 46h 0m. Cheap bus tickets for this journey start at $94 (€78) if you book in advance.
The earliest bus runs at 05:20, the last at 15:30. The fastest bus covers the 779 miles (1255 km) distance in 37h 25m.
Distance 779 miles (1255 km) |
Average bus duration 46h 0m |
Cheapest ticket price $94 (€78) |
Buses per day 4 |
Fastest bus 37h 25m |
First bus 5:20 AM |
Last bus 3:30 PM |
Cheapest Month Mar |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
One of Prague’s most significant museum institutions, preserving Jewish history through synagogues, exhibitions, and the Old Jewish Cemetery.
A leading city gallery in a Gothic landmark on Old Town Square, hosting major modern and contemporary art exhibitions.
Prague’s historic heart, surrounded by major monuments and lively at all times of day; essential for first-time visitors.
A picturesque Baroque district below Prague Castle with quiet lanes, embassies, gardens, and classic city charm.
A major boulevard-like square central to modern Czech history, shopping, and the city’s urban energy.
Marinated beef sirloin with a creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the most iconic Czech Sunday and festive dishes.
Roast pork served with bread dumplings and braised sauerkraut. This is a classic Czech pub and home-style meal strongly associated with Bohemian cooking.
Czech goulash is a rich beef stew seasoned with onion and paprika, usually served with bread dumplings. It is a staple of traditional Prague taverns and beer halls.
A Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients, tasting menus, and a sophisticated modern atmosphere.
An elegant grand café offering refined Czech and Central European dishes, excellent breakfasts, and classic pastries in a beautifully restored interior.
A well-regarded Old Town restaurant focused on updated Czech cuisine, including svíčková and goulash, in a polished but approachable setting.
Moderate for Europe: beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip is expected for fast food, but small change is appreciated in cafés.
Official public transport app
Prague Main Railway Station -> Old Town Square, Prague
Find answers to the most common questions about traveling from Thessaloniki International Airport to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
