- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Cheapest price
$174
Average price
$174
Fastest journey
1 d 4 h 40 m
Average duration
1 d 4 h 40 m
Buses per day
1
Distance
978 km
The best way to find a cheap bus ticket from Tampa, FL to Greenville, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tampa, FL to Greenville, NC will cost around $174 if you buy it on the day, but the cheapest tickets can be found for only $174.
Of the 1 buses that leave Tampa, FL for Greenville, NC on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 978 km distance in an average of 1 d 4 h 40 m but if you time it right, some buses will get you there in just 1 d 4 h 40 m .
On Sat, Jun 20 the slowest buses will take 1 d 4 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Tampa, FL to Greenville, NC among Omio's users. If you are prioritising price take the bus with prices starting from $174. For those with little time consider booking a bus which can get you there in 28h 40m. The ticket price range depends on the travel mode: a bus costs an average of $174, and a bus costs an average of $174.
Distance: 607 miles (978 km)
Most popular Bus | Driving |
|---|---|
$174 Average price Cheapest | $139 Average price (fuel + tolls) |
29h 10m Average total duration Fastest 28h 40m Onboard + 30m Additional time* | 10h 25m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 06:50AM | Arrival Time 12:30PM | Duration 29h40 | Departure days Thu, Fri, Sun | Cheapest price $155 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 12:30PM | Duration 25h20 | Departure days Wed | Cheapest price $176 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 04:30PM | Duration 28h40 | Departure days Sat | Cheapest price $174 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 12:30PM | Duration 38h05 | Departure days Wed | Cheapest price $156 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 12:30PM | Duration 37h55 | Departure days Wed | Cheapest price $135 |
The table below shows live departures for Tampa, FL to Greenville, NC buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:50 AM Tampa, FL | 28h40 | 4:30 PM Greenville, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Tampa, FL to Greenville, NC run on average 4 times per day, taking around 28h 40m. Cheap bus tickets for this journey start at $174 (€142) if you book in advance.
The earliest bus runs at 06:50, the last at 22:35. The fastest bus covers the 607 miles (978 km) distance in 28h 40m.
Distance 607 miles (978 km) |
Average bus duration 28h 40m |
Cheapest ticket price $174 (€142) |
Buses per day 4 |
Fastest bus 28h 40m |
First bus 6:50 AM |
Last bus 10:35 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
Find answers to the most common questions about traveling from Tampa, FL to Greenville, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, NC, this guide helps you travel smarter and with confidence.

Most Tampa, FL to Greenville, NC buses use the Tampa, Marion Transit Center to Greenville, S Pitt St (Butterfield Transportation Center) station pair. Use this guide to compare Tampa, FL and Greenville, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need