- Must visit
Greenville County Museum of Art
Major art museum in downtown Greenville with Southern art, traveling exhibitions, and a strong permanent collection.
Cheapest price on Oct 07
$157
Average ticket price on Oct 07
$157
Fastest journey on Oct 07
1 d 18 h 10 m
Average journey duration on Oct 07
1 d 18 h 10 m
Buses on Oct 07
1
Distance
1086 km
The best way to find a cheap bus ticket from Fort Myers, FL to Greenville, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Fort Myers, FL to Greenville, NC will cost around $157 if you buy it on the day, but the cheapest tickets can be found for only $157.
It's difficult to get from Fort Myers, FL to Greenville, NC without transferring at least 2 times.


Buses from Fort Myers, FL to Greenville, NC run on average 1 times per day, taking around 26h 21m. Cheap bus tickets for this journey start at $138 (€115) if you book in advance.
The earliest bus runs at 11:57, the last at 18:20. The fastest bus covers the 674 miles (1086 km) distance in 25h 20m.
Distance 674 miles (1086 km) |
Average bus duration 26h 21m |
Cheapest ticket price $138 (€115) |
Buses per day 1 |
Fastest bus 25h 20m |
First bus 11:57 AM |
Last bus 6:20 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jul - Sep |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Flixbus USA | Departure Time 06:20PM | Arrival Time 12:30PM | Duration 42h10 | Departure days Wed, Thu, Fri, Sat | Cheapest price $157 |
Discover the best of Greenville, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, NC trip today.
Major art museum in downtown Greenville with Southern art, traveling exhibitions, and a strong permanent collection.
Children's museum with hands-on science, art, and play exhibits designed for families and young learners.
Railway museum featuring historic cabooses and locomotives, with seasonal excursions on the Greenville and Western line.
Signature downtown park with waterfalls, gardens, lawns, and river walks centered around the Reedy River.
Tree-lined pedestrian-friendly main street with shops, public art, and easy access to downtown attractions.
Long multi-use greenway for walking and cycling that links parks, public art, and several Greenville districts.
South Carolina barbecue, often pork shoulder with a mustard-based sauce. The Upstate is known for this tangy regional style.
A Lowcountry classic of shrimp simmered in rich gravy and served over creamy grits. Popular across South Carolina, including Greenville.
Stone-ground grits cooked until creamy, often with butter and cheese. A Southern staple frequently served at breakfast in Greenville.
Upscale American restaurant known for wood-fired cooking, seasonal ingredients, and a polished downtown setting.
Stylish Southern restaurant for brunch and dinner, popular for shrimp and grits, fried chicken, and creative cocktails.
Well-known local brewery and pub offering house beers, burgers, and hearty comfort food in a relaxed atmosphere.
Moderate for U.S. travelers; hotels and dining are usually cheaper than major U.S. cities, while car-based transport can add costs.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts; small tips are appreciated.
Find answers to the most common questions about traveling from Fort Myers, FL to Greenville, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, NC, this guide helps you travel smarter and with confidence.

Most Fort Myers, FL to Greenville, NC buses use the Fort Myers, Rosa Parks Transit Center to Greenville, S Pitt St (Butterfield Transportation Center) station pair. Use this guide to compare Fort Myers, FL and Greenville, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Fort Myers, Rosa Parks Transit Center is 3 km from Fort Myers city centre. Public transport options include:
Fort Myers, Rosa Parks Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Fort Myers, Rosa Parks Transit Center. ATMs are available at Fort Myers, Rosa Parks Transit Center.
Ticket office support is available at Fort Myers, Rosa Parks Transit Center.
Available at Fort Myers, Rosa Parks Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at Fort Myers, Rosa Parks Transit Center: Wheelchair accessible routes provided.
Greenville, S Pitt St (Butterfield Transportation Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free wifi available in waiting areas. ATMs are available at Greenville, S Pitt St (Butterfield Transportation Center).
Ticket office support is available at Greenville, S Pitt St (Butterfield Transportation Center).
Available at Greenville, S Pitt St (Butterfield Transportation Center): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, S Pitt St (Butterfield Transportation Center): Wheelchair accessible entrances and seating areas.
Here are some other resources that might have the information you need