- Must visit
Greenville County Museum of Art
Major art museum in downtown Greenville with Southern art, traveling exhibitions, and a strong permanent collection.
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The cheapest and fastest buses from Frederick, MD to Greenville, NC
Showing times, prices and bookable tickets for Nov 03
- Cheapest price on Nov 03
- $74
- Average ticket price on Nov 03
- $78
- Fastest journey on Nov 03
- 11 h 55 m
- Average journey duration on Nov 03
- 11 h 55 m
- Buses on Nov 03
- 2
- Distance
- 423 km
Cheap tickets
The best way to find a cheap bus ticket from Frederick, MD to Greenville, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Greenville, NC will cost around $78 if you buy it on the day, but the cheapest tickets can be found for only $74.
Fast buses
On Tue, Nov 03, we found 2 buses from Frederick, MD to Greenville, NC, including 2 direct services.
On Tue, Nov 03 the direct buses cover the 423 km distance in an average of 11 h 55 m but if you time it right, some buses will get you there in just 11 h 55 m .
On Tue, Nov 03 the slowest buses will take 11 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:35 AM 11h55 Frederick, MD 4:30 PM Greenville, NC $74 1 One-way 0 transfers5:35 AM 11h55 Frederick, MD 5:30 PM Greenville, NC $82 1 One-way 0 transfers
5:35 AM 11h55 Frederick, MD 5:30 PM Greenville, NC $82 1 One-way 0 transfers4:35 AM 11h55 Frederick, MD 4:30 PM Greenville, NC $74 1 One-way 0 transfers
Journey information
Overview: Bus from Frederick, MD to Greenville, NC
USAUSA
Take a bus from Frederick, MD to Greenville, NC and enjoy the approximately 262 miles (423 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Plan this route
Journey facts
- Distance262 miles (423 km)
- Cheapest MonthMar
- Cheapest DayWed
- High SeasonJan - Mar
- Low SeasonJan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frederick, MD to Greenville, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:35AM | Arrival Time 04:30PM | Duration 11h55 | Departure days Everyday | Cheapest price $74 |
Operator Greyhound | Departure Time 05:35AM | Arrival Time 05:30PM | Duration 11h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $82 |
Live departures
Frederick, MD to Greenville, NC bus times
The table below shows live departures for Frederick, MD to Greenville, NC buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 4:35 AM Frederick, MD | 11h55 | 4:30 PM Greenville, NC | 0 transfersDirect | |
| 5:35 AM Frederick, MD | 11h55 | 5:30 PM Greenville, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Complete guide to Greenville, NC
Things to do in Greenville, NC
Discover the best of Greenville, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, NC trip today.
- Recommended
The Children's Museum of the Upstate
Children's museum with hands-on science, art, and play exhibits designed for families and young learners.
- Recommended
Upcountry History Museum
Railway museum featuring historic cabooses and locomotives, with seasonal excursions on the Greenville and Western line.
- Must visit
Falls Park on the Reedy
Signature downtown park with waterfalls, gardens, lawns, and river walks centered around the Reedy River.
- Must visit
Main Street
Tree-lined pedestrian-friendly main street with shops, public art, and easy access to downtown attractions.
- Recommended
Prisma Health Swamp Rabbit Trail
Long multi-use greenway for walking and cycling that links parks, public art, and several Greenville districts.
- Gluten-free
Mustard-Based Barbecue
South Carolina barbecue, often pork shoulder with a mustard-based sauce. The Upstate is known for this tangy regional style.
- Gluten-free
Shrimp And Grits
A Lowcountry classic of shrimp simmered in rich gravy and served over creamy grits. Popular across South Carolina, including Greenville.
- Vegetarian
- Gluten-free
Cheese Grits
Stone-ground grits cooked until creamy, often with butter and cheese. A Southern staple frequently served at breakfast in Greenville.
Jianna
Upscale American restaurant known for wood-fired cooking, seasonal ingredients, and a polished downtown setting.
Soby's
Stylish Southern restaurant for brunch and dinner, popular for shrimp and grits, fried chicken, and creative cocktails.
Yee-Haw Brewing Greenville
Well-known local brewery and pub offering house beers, burgers, and hearty comfort food in a relaxed atmosphere.
United States dollar ($)
Moderate for U.S. travelers; hotels and dining are usually cheaper than major U.S. cities, while car-based transport can add costs.
Average meal costs
- Budget
- $10-15 for fast food or a casual meal.
- Mid-range
- $18-35 per person for a restaurant meal.
- Fine dining
- $50+ per person for upscale restaurants.
- Coffee
- $3-5 for cappuccino or latte.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts; small tips are appreciated.
Plan your visit to Greenville, NC
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Greenville, NC.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, NC, travelers should be cautious of petty theft and vehicle break-ins, especially in crowded or tourist-heavy areas. Common scams include overcharging by unofficial taxi or ride-share services and unsolicited offers for tours or accommodations. It’s advisable to use licensed transportation, keep valuables secure, and remain aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Frederick, MD to Greenville, NC
Find answers to the most common questions about traveling from Frederick, MD to Greenville, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, NC, this guide helps you travel smarter and with confidence.
Yes, you can take a between Frederick, MD and Greenville, NC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Frederick, MD to Greenville, NC
Most Frederick, MD to Greenville, NC buses use the Frederick, East Street (Transit Center) to Greenville, S Pitt St (Butterfield Transportation Center) station pair. Use this guide to compare Frederick, MD and Greenville, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Frederick
Arrival bus stations in Greenville
Which Frederick, MD station do buses to Greenville, NC leave from?
Buses from Frederick, MD to Greenville, NC leave from Frederick, East Street (Transit Center). The station is 0 miles (1 km) from Frederick, MD city centre at Frederick, MD, USA.
Frederick, East Street (Transit Center)Frederick, MD, USA
City-centre transport
Getting to Frederick, East Street (Transit Center) from Frederick city centre
TrainSouthwest Chief · 63h 13m · $949
Southwest Chief · 67h 1m · $1,160
BusGreyhound US1210 · 63h 11m · $630
Frederick, East Street (Transit Center) bus station facilities and services
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Tickets and information
Ticket office support is available at Frederick, East Street (Transit Center).
Parking, taxis and toilets
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Which Greenville, NC station do buses from Frederick, MD arrive at?
Buses from Frederick, MD to Greenville, NC arrive at Greenville, S Pitt St (Butterfield Transportation Center). Greenville, S Pitt St (Butterfield Transportation Center) is 0 miles (1 km) from Greenville, NC city centre.
Greenville, S Pitt St (Butterfield Transportation Center)600 S Pitt St, Greenville, NC 27834, USA
City-centre transport
Getting to Greenville, S Pitt St (Butterfield Transportation Center) from Greenville city centre
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Greenville, S Pitt St (Butterfield Transportation Center) bus station facilities and services
Greenville, S Pitt St (Butterfield Transportation Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free wifi available in waiting areas. ATMs are available at Greenville, S Pitt St (Butterfield Transportation Center).
Tickets and information
Ticket office support is available at Greenville, S Pitt St (Butterfield Transportation Center).
Parking, taxis and toilets
Available at Greenville, S Pitt St (Butterfield Transportation Center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, S Pitt St (Butterfield Transportation Center): Wheelchair accessible entrances and seating areas.
Bus stations for Frederick, MD to Greenville, NC
Check bus stations information for Frederick, MD and Greenville, NC, including where buses depart and arrive on this route.
Passengers board the bus most frequently from Frederick, East Street (Transit Center), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Greenville, S Pitt St (Butterfield Transportation Center), located 1 away from the city centre.
Most popular buses to and from Greenville, NC and Frederick, MD
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