- Must visit
Greenville County Museum of Art
Major art museum known for its Southern art collection and works by Andrew Wyeth and Jasper Johns. One of the city’s top cultural attractions.
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The cheapest and fastest buses from Myrtle Beach, SC to Greenville, NC
Showing times and prices for Jun 01
Cheapest price
$56
Average price
$56
Fastest journey
5 h 45 m
Average duration
5 h 45 m
Buses per day
1
Distance
255 km
Cheap tickets
The best way to find a cheap bus ticket from Myrtle Beach, SC to Greenville, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Myrtle Beach, SC to Greenville, NC will cost around $56 if you buy it on the day, but the cheapest tickets can be found for only $56.
Fast buses
Of the 1 buses that leave Myrtle Beach, SC for Greenville, NC on Mon, Jun 01, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 01 the direct buses cover the 255 km distance in an average of 5 h 45 m but if you time it right, some buses will get you there in just 5 h 45 m .
On Mon, Jun 01 the slowest buses will take 5 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:45 PM5h45Myrtle Beach, SC10:30 PMGreenville, NC$561One-way0 transfers
- 4:45 PM5h45Myrtle Beach, SC10:30 PMGreenville, NC$561One-way0 transfers
Travel Information
Compare bus for Myrtle Beach, SC to Greenville, NC
Omio recommends booking the bus as it is the most popular option from Myrtle Beach, SC to Greenville, NC among Omio's users. If you are prioritising price take the bus with prices starting from $42. For those with little time consider booking a bus which can get you there in 5h 35m. The ticket price range depends on the travel mode: a bus costs an average of $42, and a bus costs an average of $42.
Distance: 158 miles (255 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$49 Average price Cheapest | $38 Average price (fuel + tolls) |
6h 5m Average total duration Fastest 5h 35m Onboard + 30m Additional time* | 3h 34m Average total duration (door-to-door) |
Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
The cheapest way to travel from Myrtle Beach, SC to Greenville, NC is a bus with an average price of $49 (€40).
The fastest way to travel from Myrtle Beach, SC to Greenville, NC is by bus with an average journey time of 5h 35m.
Yes, you can take a bus between Myrtle Beach, SC and Greenville, NC.
We recommend using the bus as it is the most popular way to get from Myrtle Beach, SC to Greenville, NC among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about -3h -1m sooner (5h 35m by bus vs 3h 34m by car) and save roughly $-11.02 (€-8.87) compared to fuel and tolls ($49 (€40) vs $38 (€31)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Myrtle Beach, SC to Greenville, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:45PM | Arrival Time 06:30PM | Duration 5h45 | Departure days Thu, Fri, Sat, Sun | Cheapest price $50 |
Operator Greyhound | Departure Time 04:45PM | Arrival Time 10:30PM | Duration 5h45 | Departure days Mon | Cheapest price $56 |
Operator Greyhound | Departure Time 05:45PM | Arrival Time 11:30PM | Duration 5h45 | Departure days Wed | Cheapest price $42 |
Live departures
Myrtle Beach, SC to Greenville, NC bus times
The table below shows live departures for Myrtle Beach, SC to Greenville, NC buses for today, Sunday, May 31. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:45 PM Myrtle Beach, SC | 5h45 | 6:30 PM Greenville, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Myrtle Beach, SC to Greenville, NC by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Myrtle Beach, SC to Greenville, NC buses with Omio?
Greyhound operates all buses services from Myrtle Beach, SC to Greenville, NC.
Omio is an official ticket reseller for all your travel options from Myrtle Beach, SC to Greenville, NC.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Myrtle Beach, SC to Greenville, NC
USAUSA
Buses from Myrtle Beach, SC to Greenville, NC run on average 1 times per day, taking around 5h 35m. Cheap bus tickets for this journey start at $42 (€34) if you book in advance.
There are 1 buses per day. The earliest bus runs at 11:20, the last at 12:45. The fastest bus covers the 158 miles (255 km) distance in 5h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 158 miles (255 km) |
Average bus duration 5h 35m |
Cheapest ticket price $42 (€34) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 5h 45m |
First bus 11:20 AM |
Last bus 12:45 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Apr - Jun |
Best time to book 35 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Myrtle Beach, SC to Greenville, NCYou can travel by bus between Myrtle Beach, SC to Greenville, NC with Greyhound for as low as $42 (€34). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
5h 45m
Cheapest Price
$42 (€34)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Greenville
Things to do in Greenville
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
- Recommended
Upcountry History Museum
Regional history museum with rotating exhibitions on the Upstate’s people, industry, and culture. A strong choice for understanding Greenville beyond downtown.
- Recommended
Sigal Music Museum
Specialized museum displaying historic string, keyboard, and wind instruments from around the world. A lesser-known but distinctive Greenville stop.
- Must visit
Main Street
The core downtown street lined with shops, public art, plazas, and event spaces. It is Greenville’s main walking corridor and a top first stop.
- Must visit
Swamp Rabbit Trail
Multi-use greenway linking Greenville with nearby communities. Highly popular for walking and cycling, and one of the city’s most loved outdoor assets.
- Recommended
West End Historic District
Lively downtown district near Falls Park known for baseball, galleries, restored buildings, and a strong local atmosphere. Popular for strolling and photos.
- Gluten-free
South Carolina Barbecue
Slow-smoked pork, often chopped or pulled, served with the state's famous mustard-based 'Carolina Gold' sauce. It is a defining Upstate and statewide tradition.
- Vegetarian
Fried Green Tomatoes
Unripe green tomatoes sliced, breaded, and fried until crisp. A classic Southern starter found on many Greenville-area menus.
- Gluten-free
Shrimp And Grits
Creamy stone-ground grits topped with shrimp, often with bacon, gravy, or a rich butter sauce. A beloved Lowcountry and broader South Carolina favorite.
The Anchorage
Acclaimed neighborhood restaurant focused on seasonal Southern-influenced cooking, thoughtful plates, and a more polished dining experience.
Soby's New South Cuisine
A long-running downtown favorite serving refined Southern cuisine, including shrimp and grits and seasonal regional dishes, in a lively historic setting.
Jianna
Stylish downtown restaurant known for handmade pasta, oysters, and city views. It is one of Greenville's best-known upscale dining rooms.
United States Dollar
Costs are moderate by U.S. standards. Dining is reasonable, while hotels rise during events and peak weekends.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-35 per person at a casual sit-down restaurant.
- Fine dining
- USD 50-100+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% in restaurants; 20%+ for excellent service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for coffee if desired.
FAQs: Bus from Myrtle Beach, SC to Greenville, NC
Find answers to the most common questions about traveling from Myrtle Beach, SC to Greenville, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, NC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Myrtle Beach, SC to Greenville, NC can start from as little as $42 (€34) when you book in advance. The average bus ticket price for Myrtle Beach, SC to Greenville, NC is $49 (€40) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Myrtle Beach, SC to Greenville, NC is 5h 45m to travel the 158 miles (255 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Myrtle Beach, SC to Greenville, NC leaves at 11:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Myrtle Beach, SC to Greenville, NC leaves at 12:45 PM.
Yes, there are 1 direct buses a day from Myrtle Beach, SC to Greenville, NC with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Myrtle Beach, SC to Greenville, NC, you can count on Greyhound for the best way to get you to Greenville, NC. You can also check all possible bus companies who offer a service between Myrtle Beach, SC and Greenville, NC and compare the amenities they offer before buying a bus ticket.
A trip to Greenville, NC from Myrtle Beach, SC is worth doing but not as a day trip with a journey time of 5h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Myrtle Beach, SC to Greenville, NC is August.
Yes, you can take a bus between Myrtle Beach, SC and Greenville, NC.
Yes, the following accessibility options are available when taking the bus from Myrtle Beach, SC to Greenville, NC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Myrtle Beach, SC to Greenville, NC for bus company Greyhound.
Whether you can cancel your bus ticket from Myrtle Beach, SC to Greenville, NC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Myrtle Beach, SC to Greenville, NC.
Yes, the following luggage options are included when booking a bus ticket from Myrtle Beach, SC to Greenville, NC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Myrtle Beach, SC to Greenville, NC:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Myrtle Beach, SC to Greenville, NC.
You can reserve your seat on the bus from Myrtle Beach, SC to Greenville, NC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Myrtle Beach, SC to Greenville, NC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Myrtle Beach, SC to Greenville, NC with the following bus company: Greyhound.
Since neither Myrtle Beach, SC nor Greenville, NC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Myrtle Beach, SC to Greenville, NC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, NC, travelers should be cautious of petty theft and vehicle break-ins, especially in crowded or tourist-heavy areas. Common scams include overcharging by unofficial taxi or ride-share services and unsolicited offers for tours or accommodations. It’s advisable to use licensed transportation, keep valuables secure, and remain aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Myrtle Beach, SC to Greenville, NC
Myrtle Beach
Greenville
The major bus station for departures in Myrtle Beach is Myrtle Beach, N Oak St (Bus Station). Find all the information you need to know about services, amenities and connections at Myrtle Beach, N Oak St (Bus Station) for your trip from Myrtle Beach to Greenville.
Myrtle Beach, N Oak St (Bus Station)
information
The major bus station for arrivals in Greenville is Greenville, S Pitt St (Butterfield Transportation Center). Find all the information you need to know about services, amenities and connections at Greenville, S Pitt St (Butterfield Transportation Center) for your trip to Greenville from Myrtle Beach.
Greenville, S Pitt St (Butterfield Transportation Center)
information
Most popular bus connections from Myrtle Beach, SC
More options for your journey from Myrtle Beach, SC to Greenville, NC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, NC and Myrtle Beach, SC
Most popular bus connections to Greenville, NC
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