- Must visit
Greenville County Museum of Art
Major art museum in downtown Greenville with Southern art, traveling exhibitions, and a strong permanent collection.
Cheapest price on Oct 21
Kč 881
Average ticket price on Oct 21
Kč 881
Fastest journey on Oct 21
5 h 45 m
Average journey duration on Oct 21
5 h 45 m
Buses on Oct 21
1
Distance
255 km
The best way to find a cheap bus ticket from Myrtle Beach, SC to Greenville, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Myrtle Beach, SC to Greenville, NC will cost around Kč 881 if you buy it on the day, but the cheapest tickets can be found for only Kč 881.
On Wed, Oct 21, we found 1 buses from Myrtle Beach, SC to Greenville, NC, including 1 direct services.
On Wed, Oct 21 the direct buses cover the 255 km distance in an average of 5 h 45 m but if you time it right, some buses will get you there in just 5 h 45 m .
On Wed, Oct 21 the slowest buses will take 5 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Buses from Myrtle Beach, SC to Greenville, NC run on average 1 times per day, taking around 5h 54m. Cheap bus tickets for this journey start at Kč 700 if you book in advance.
There are 1 buses per day. The earliest bus runs at 11:20, the last at 12:45. The fastest bus covers the 158 miles (255 km) distance in 5h 45m.
Distance 158 miles (255 km) |
Average bus duration 5h 54m |
Cheapest ticket price Kč 700 |
Buses per day 1 |
Direct buses 1 |
Fastest bus 5h 45m |
First bus 11:20 AM |
Last bus 12:45 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Apr - Jun |
Best time to book 35 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:45PM | Arrival Time 06:30PM | Duration 5h45 | Departure days Thu, Fri, Sat, Sun | Cheapest price Kč 1,033 |
Operator Greyhound | Departure Time 04:45PM | Arrival Time 10:30PM | Duration 5h45 | Departure days Mon | Cheapest price Kč 1,174 |
Operator Greyhound | Departure Time 05:45PM | Arrival Time 11:30PM | Duration 5h45 | Departure days Wed | Cheapest price Kč 881 |
Discover the best of Greenville, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, NC trip today.
Major art museum in downtown Greenville with Southern art, traveling exhibitions, and a strong permanent collection.
Children's museum with hands-on science, art, and play exhibits designed for families and young learners.
Railway museum featuring historic cabooses and locomotives, with seasonal excursions on the Greenville and Western line.
Signature downtown park with waterfalls, gardens, lawns, and river walks centered around the Reedy River.
Tree-lined pedestrian-friendly main street with shops, public art, and easy access to downtown attractions.
Long multi-use greenway for walking and cycling that links parks, public art, and several Greenville districts.
South Carolina barbecue, often pork shoulder with a mustard-based sauce. The Upstate is known for this tangy regional style.
A Lowcountry classic of shrimp simmered in rich gravy and served over creamy grits. Popular across South Carolina, including Greenville.
Stone-ground grits cooked until creamy, often with butter and cheese. A Southern staple frequently served at breakfast in Greenville.
Upscale American restaurant known for wood-fired cooking, seasonal ingredients, and a polished downtown setting.
Stylish Southern restaurant for brunch and dinner, popular for shrimp and grits, fried chicken, and creative cocktails.
Well-known local brewery and pub offering house beers, burgers, and hearty comfort food in a relaxed atmosphere.
Moderate for U.S. travelers; hotels and dining are usually cheaper than major U.S. cities, while car-based transport can add costs.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts; small tips are appreciated.
Find answers to the most common questions about traveling from Myrtle Beach, SC to Greenville, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, NC, this guide helps you travel smarter and with confidence.

Most Myrtle Beach, SC to Greenville, NC buses use the Myrtle Beach, N Oak St (Bus Station) to Greenville, S Pitt St (Butterfield Transportation Center) station pair. Use this guide to compare Myrtle Beach, SC and Greenville, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Myrtle Beach, N Oak St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Myrtle Beach, N Oak St (Bus Station). ATMs are available at Myrtle Beach, N Oak St (Bus Station).
Ticket office support is available at Myrtle Beach, N Oak St (Bus Station).
Available at Myrtle Beach, N Oak St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Myrtle Beach, N Oak St (Bus Station): Wheelchair accessible entry available.
Greenville, S Pitt St (Butterfield Transportation Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free wifi available in waiting areas. ATMs are available at Greenville, S Pitt St (Butterfield Transportation Center).
Ticket office support is available at Greenville, S Pitt St (Butterfield Transportation Center).
Available at Greenville, S Pitt St (Butterfield Transportation Center): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, S Pitt St (Butterfield Transportation Center): Wheelchair accessible entrances and seating areas.
Here are some other resources that might have the information you need