- Must visit
Vatican Museums
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
Cheapest price
$34
Average price
$34
Fastest journey
7 h 9 m
Average duration
7 h 9 m
Buses per day
1
Distance
240 km
The best way to find a cheap bus ticket from Sesto Fiorentino to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Sesto Fiorentino to Rome will cost around $34 if you buy it on the day, but the cheapest tickets can be found for only $34.
Of the 1 buses that leave Sesto Fiorentino for Rome on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 240 km distance in an average of 7 h 9 m but if you time it right, some buses will get you there in just 7 h 9 m .
On Sun, Jun 21 the slowest buses will take 7 h 9 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Sesto Fiorentino to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $8. For those with little time consider booking a flight which can get you there in 1h 43m. The ticket price range depends on the travel mode: a bus costs an average of $8, and a flight costs an average of $79.
Distance: 149 miles (240 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$15 Average price Cheapest | $31 Average price | $301 Average price |
3h 45m Average total duration 3h 15m Onboard + 30m Additional time* | 2h 28m Average total duration 1h 58m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 1h 43m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Sesto Fiorentino to Rome:
A bus is $17 (€14) less than a train for this route with tickets for a train from Sesto Fiorentino to Rome costing on average $31 (€26).
A bus is $286 (€234) less than a flight for this route with tickets for a flight from Sesto Fiorentino to Rome costing on average $301 (€246).
Other travel options to Rome take longer:
Train takes on average 1h 58m.
Bus takes on average 3h 15m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Trenitalia | Departure Time 07:56AM | Arrival Time 03:05PM | Duration 7h09 | Departure days Sun | Cheapest price $34 |
Operator Itabus | Departure Time 09:10AM | Arrival Time 01:00PM | Duration 3h50 | Departure days Mon | Cheapest price $9 |
Operator BlaBlaCar Bus | Departure Time 03:45PM | Arrival Time 07:15PM | Duration 3h30 | Departure days Mon, Fri | Cheapest price $8 |
Operator Itabus | Departure Time 06:30PM | Arrival Time 09:45PM | Duration 3h15 | Departure days Mon, Thu | Cheapest price $9 |
Operator Autolinee Toscane - Urbano Area Metropolitana Fiorentina | Departure Time 11:42PM | Arrival Time 06:10AM | Duration 6h28 | Departure days Wed | Cheapest price $0.00 |
Operator Autolinee Toscane - Urbano Area Metropolitana Fiorentina | Departure Time 11:51PM | Arrival Time 06:10AM | Duration 6h19 | Departure days Sat | Cheapest price $0.00 |
The table below shows live departures for Sesto Fiorentino to Rome buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:51 PM Sesto Fiorentino | 6h19 | 6:10 AM Rome | 2 transfers | |
| Sunday, June 21 | |||||
![]() | 7:56 AM Sesto Fiorentino | 7h09 | 3:05 PM Rome | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Sesto Fiorentino to Rome run on average 51 times per day, taking around 3h 15m. Cheap bus tickets for this journey start at $8 (€7) if you book in advance.
There are 48 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 149 miles (240 km) distance in 3h 15m.
Distance 149 miles (240 km) |
Average bus duration 3h 15m |
Cheapest ticket price $8 (€7) |
Buses per day 51 |
Direct buses 48 |
Fastest bus 3h 15m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 6 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
A celebrated villa museum with major works by Bernini, Caravaggio, and Canova, set inside Villa Borghese gardens. Timed-entry tickets are required and usually need advance reservation.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, sculpture, paintings, and superb views over the Forum area.
A grand Baroque square lined with fountains, churches, and elegant facades. It remains one of Rome’s classic walking and people-watching spots.
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti, popular for photos, shopping nearby, and city atmosphere.
A characterful district of narrow lanes, ivy-covered facades, and lively evening atmosphere, widely loved for wandering and street photography.
A classic Roman pasta with Pecorino Romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, Pecorino Romano, and black pepper. It is a defining dish of Rome and should not contain cream.
Pasta with tomato, guanciale, Pecorino Romano, and chili. Though linked with Amatrice, it is a staple on Roman menus and deeply rooted in local cooking.
A historic trattoria near the Pantheon, respected for traditional Roman dishes such as carbonara, amatriciana, and seasonal specialties in an intimate atmosphere.
A celebrated central Rome dining room and delicatessen known for classic Roman pasta, cured meats, and an exceptional wine list in a lively upscale setting.
A famous Trastevere trattoria known for authentic Roman comfort food, including cacio e pepe, meatballs, and artichokes, with a classic casual feel.
Moderate for Western Europe: food and coffee can be reasonable, but hotels and major tourist areas cost more.
Service is often included or modest. Locals may round up or leave EUR 1-2 for coffee, 5-10% for good restaurant service; tips are appreciated, not required.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Sesto Fiorentino to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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