- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price
$19
Average price
$19
Fastest journey
3 h 15 m
Average duration
3 h 15 m
Buses per day
1
Distance
240 km
The best way to find a cheap bus ticket from Sesto Fiorentino to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Sesto Fiorentino to Rome will cost around $19 if you buy it on the day, but the cheapest tickets can be found for only $19.
Of the 1 buses that leave Sesto Fiorentino for Rome on Thu, Aug 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct buses cover the 240 km distance in an average of 3 h 15 m but if you time it right, some buses will get you there in just 3 h 15 m .
On Thu, Aug 06 the slowest buses will take 3 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Sesto Fiorentino to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $9. For those with little time consider booking a flight which can get you there in 1h 43m. The ticket price range depends on the travel mode: a bus costs an average of $9, and a flight costs an average of $79.
Distance: 149 miles (240 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$15 Average price Cheapest | $32 Average price | $303 Average price |
3h 45m Average total duration 3h 15m Onboard + 30m Additional time* | 2h 28m Average total duration 1h 58m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 1h 43m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Sesto Fiorentino to Rome:
A bus is $17 less than a train for this route with tickets for a train from Sesto Fiorentino to Rome costing on average $32.
A bus is $288 less than a flight for this route with tickets for a flight from Sesto Fiorentino to Rome costing on average $303.
Other travel options to Rome take longer:
Train takes on average 1h 58m.
Bus takes on average 3h 15m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Trenitalia | Departure Time 07:56AM | Arrival Time 03:05PM | Duration 7h09 | Departure days Sun | Cheapest price $34 |
Operator Itabus | Departure Time 09:10AM | Arrival Time 01:00PM | Duration 3h50 | Departure days Mon | Cheapest price $9 |
Operator BlaBlaCar Bus | Departure Time 03:45PM | Arrival Time 07:15PM | Duration 3h30 | Departure days Mon, Fri | Cheapest price $9 |
Operator Itabus | Departure Time 06:30PM | Arrival Time 09:45PM | Duration 3h15 | Departure days Mon, Thu | Cheapest price $9 |
Operator Autolinee Toscane - Urbano Area Metropolitana Fiorentina | Departure Time 11:42PM | Arrival Time 06:10AM | Duration 6h28 | Departure days Wed | Cheapest price $0.00 |
Operator Autolinee Toscane - Urbano Area Metropolitana Fiorentina | Departure Time 11:51PM | Arrival Time 06:10AM | Duration 6h19 | Departure days Sat | Cheapest price $0.00 |
The table below shows live departures for Sesto Fiorentino to Rome buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:42 PM Sesto Fiorentino | 6h28 | 6:10 AM Rome | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Sesto Fiorentino to Rome run on average 51 times per day, taking around 3h 15m. Cheap bus tickets for this journey start at $9 if you book in advance.
There are 48 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 149 miles (240 km) distance in 3h 15m.
Distance 149 miles (240 km) |
Average bus duration 3h 15m |
Cheapest ticket price $9 |
Buses per day 51 |
Direct buses 48 |
Fastest bus 3h 15m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 6 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Sesto Fiorentino to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Sesto Fiorentino to Rome buses use the Scandicci, Villa Costanza (Firenze) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Sesto Fiorentino and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Here are some other resources that might have the information you need