- Must visit
Vatican Museums
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
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Travel Information
Compare flight for Santorini (Island) to Rome
Omio recommends booking the flight as it is the most popular option from Santorini (Island) to Rome among Omio's users. If you are prioritising price take the flight with prices starting from $100. For those with little time consider booking a flight which can get you there in 3h 28m. The ticket price range depends on the travel mode: a flight costs an average of $100, and a flight costs an average of $100.
Distance: 791 miles (1273 km)
Compare flight with
Most popular Flight | Driving |
|---|---|
$242 Average price Cheapest | $102 Average price (fuel + tolls) |
6h 28m Average total duration Fastest 3h 28m Onboard + 3h 0m Additional time* | 28h 20m Average total duration (door-to-door) |
 Most popular airline | Your own car or car rental |
Direct Options | Direct Options |
The cheapest way to travel from Santorini (Island) to Rome is a flight with an average price of $242 (€200).
The fastest way to travel from Santorini (Island) to Rome is by flight with an average journey time of 3h 28m.
Yes, you can take a flight between Santorini (Island) and Rome.
We recommend using the flight as it is the most popular way to get from Santorini (Island) to Rome among Omio's users.
Compare prices and tickets Santorini (Island) to Rome by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Santorini (Island) to Rome
Greece
Italy
Take a bus from Santorini (Island) to Rome and enjoy the approximately 791 miles (1273 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $100 (€82)
Distance 791 miles (1273 km) |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Thu |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $100 (€82)
Complete guide to Rome
Things to do in Rome
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
- Must visit
Galleria Borghese
A celebrated villa museum with major works by Bernini, Caravaggio, and Canova, set inside Villa Borghese gardens. Timed-entry tickets are required and usually need advance reservation.
- Recommended
Capitoline Museums
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, sculpture, paintings, and superb views over the Forum area.
- Must visit
Piazza Navona
A grand Baroque square lined with fountains, churches, and elegant facades. It remains one of Rome’s classic walking and people-watching spots.
- Must visit
Spanish Steps
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti, popular for photos, shopping nearby, and city atmosphere.
- Must visit
Trastevere
A characterful district of narrow lanes, ivy-covered facades, and lively evening atmosphere, widely loved for wandering and street photography.
- Vegetarian
Cacio E Pepe
A classic Roman pasta with Pecorino Romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Carbonara
Traditional Roman pasta made with guanciale, egg yolk, Pecorino Romano, and black pepper. It is a defining dish of Rome and should not contain cream.
Amatriciana
Pasta with tomato, guanciale, Pecorino Romano, and chili. Though linked with Amatrice, it is a staple on Roman menus and deeply rooted in local cooking.
Armando Al Pantheon
A historic trattoria near the Pantheon, respected for traditional Roman dishes such as carbonara, amatriciana, and seasonal specialties in an intimate atmosphere.
Roscioli Salumeria Con Cucina
A celebrated central Rome dining room and delicatessen known for classic Roman pasta, cured meats, and an exceptional wine list in a lively upscale setting.
Da Enzo Al 29
A famous Trastevere trattoria known for authentic Roman comfort food, including cacio e pepe, meatballs, and artichokes, with a classic casual feel.
Euro
Moderate for Western Europe: food and coffee can be reasonable, but hotels and major tourist areas cost more.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or takeaway.
- Mid-range
- EUR 20-35 per person at a casual restaurant.
- Fine dining
- EUR 70+ per person at upscale restaurants.
- Coffee
- EUR 1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or modest. Locals may round up or leave EUR 1-2 for coffee, 5-10% for good restaurant service; tips are appreciated, not required.
TicketAppy
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.50
- Day pass
- EUR 7.00
To the city center
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
- Distance
- 0.4 km
- Travel time
- 5 min
- A BIT ticket is valid for 100 min on buses, trams, metro, and urban rail, but only one metro entry is allowed. Validate your ticket at the start of the journey.
- Onboard card payment is not generally available on Rome buses and trams, so buy and validate tickets in advance or use official digital ticket options.
FAQs: Bus from Santorini (Island) to Rome
Find answers to the most common questions about traveling from Santorini (Island) to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.
Yes, you can take a flight between Santorini (Island) and Rome.
No, the bus from Santorini (Island) to Rome has no accessibility options.
No, there are no bathrooms on board the bus from Santorini (Island) to Rome.
Some of the most interesting sights to explore in Rome are:
- Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
- Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
- Roman Forum, the ruins of ancient Rome's center for public life and government
- Pantheon, a well-preserved Roman temple with a striking dome and oculus
- Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.
The best things to do in Rome include:
- Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
- Take a stroll through Villa Borghese, a beautiful park with museums and gardens
- Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
- Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
- Discover the Catacombs, ancient underground burial sites with guided tours.
No, bikes are not allowed on board the bus from Santorini (Island) to Rome.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Santorini (Island) to Rome.
No, luggage for the bus from Santorini (Island) to Rome needs to be booked in addition.
No, there are no additional luggage options for the bus from Santorini (Island) to Rome.
Unfortunately, pets are not allowed on the bus from Santorini (Island) to Rome.
No, there are no USB plugs on board the bus from Santorini (Island) to Rome.
No, there is no WiFi on board the bus from Santorini (Island) to Rome.
Since both Santorini (Island) and Rome are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Santorini (Island) to Rome among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Rome, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, major landmarks, and popular squares. Common scams include unofficial taxi drivers overcharging and street vendors selling counterfeit goods. It's advisable to use authorized taxis, keep valuables secure, and be wary of distraction techniques used by scammers in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
More options for your journey from Santorini (Island) to Rome
Here are some other resources that might have the information you need
Most popular buses to and from Rome and Santorini (Island)
Most popular bus connections to Rome
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