- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and vast papal collections. Timed entry is strongly recommended due to heavy demand.
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Travel Information
Compare flight for Santorini (Island) to Rome
Omio recommends booking the flight as it is the most popular option from Santorini (Island) to Rome among Omio's users. If you are prioritising price take the flight with prices starting from $102. For those with little time consider booking a flight which can get you there in 3h 28m. The ticket price range depends on the travel mode: a flight costs an average of $102, and a flight costs an average of $102.
Distance: 791 miles (1273 km)
Compare flight with
Most popular Flight | Driving |
|---|---|
$247 Average price Cheapest | $104 Average price (fuel + tolls) |
6h 28m Average total duration Fastest 3h 28m Onboard + 3h 0m Additional time* | 28h 20m Average total duration (door-to-door) |
 Most popular airline | Your own car or car rental |
Direct Options | Direct Options |
The cheapest way to travel from Santorini (Island) to Rome is a flight with an average price of $247 (€200).
The fastest way to travel from Santorini (Island) to Rome is by flight with an average journey time of 3h 28m.
Yes, you can take a flight between Santorini (Island) and Rome.
We recommend using the flight as it is the most popular way to get from Santorini (Island) to Rome among Omio's users.
Compare prices and tickets Santorini (Island) to Rome by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Santorini (Island) to Rome
Greece
Italy
Take a bus from Santorini (Island) to Rome and enjoy the approximately 791 miles (1273 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $102 (€82)
Distance 791 miles (1273 km) |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Thu |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $102 (€82)
Complete guide to Rome
Things to do in Rome
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
- Must visit
Galleria Borghese
Premier art gallery in Villa Borghese, known for Bernini sculptures and masterpieces by Caravaggio and Raphael. Advance reservation is typically required.
- Recommended
Capitoline Museums
Rome’s historic civic museums on Capitoline Hill, featuring ancient Roman sculpture, bronzes, and sweeping views over the Forum.
- Must visit
Piazza Navona
Elegant baroque square famed for Bernini fountains, church facades, and lively street atmosphere. A classic place to stroll day or night.
- Must visit
Trastevere
Beloved neighborhood of narrow lanes, ivy-clad buildings, and vibrant evening life, popular with both locals and visitors.
- Must visit
Spanish Steps
Iconic monumental staircase and social gathering point linking Piazza di Spagna with Trinità dei Monti, especially photogenic at golden hour.
- Vegetarian
Cacio e Pepe
Iconic Roman pasta made with tonnarelli or spaghetti, Pecorino Romano, and black pepper. A minimalist classic strongly associated with Rome.
Carbonara
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. It is one of the city’s most famous traditional dishes.
Amatriciana
Roman favorite of pasta dressed with tomato, guanciale, Pecorino Romano, and chili or black pepper. Deeply rooted in local trattoria culture.
La Pergola
Rome’s landmark fine-dining restaurant offering refined Italian cuisine, luxury service, and panoramic city views. Best for a splurge experience.
Armando al Pantheon
Historic trattoria near the Pantheon, famous for classic Roman dishes such as carbonara, amatriciana, and seasonal specialties. Traditional and intimate.
Roscioli Salumeria con Cucina
Celebrated central Rome dining room known for Roman pasta, cured meats, cheeses, and an excellent wine list. Busy, polished, and very popular.
Euro
Compared with many Western European capitals, Rome is moderate overall: budget dining is accessible, but central hotels and tourist-area restaurants can be costly.
Average meal costs
- Budget
- EUR 8-15 for pizza al taglio, panini, or simple trattoria meals.
- Mid-range
- EUR 20-40 per person for a meal at a mid-range restaurant.
- Fine dining
- EUR 80+ per person at upscale restaurants, often more with wine.
- Coffee
- EUR 1.20-2.50 for espresso or cappuccino, depending on bar service or table service.
Tipping culture
Service is often included or reflected in menu prices, and tipping is not as obligatory as in some countries. In restaurants, rounding up the bill or leaving about EUR 1-5 for good service is common;
TicketAppy
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.50
- Day pass
- EUR 7.00
To the city center
Rome, Via Marsala / Viale Enrico De Nicola, Rome -> Roma Termini, Rome
- Distance
- 0.3 km
- Travel time
- 4 min
- A BIT ticket is valid for 100 min on buses, trams, and metro, with one metro entry allowed. Validate it at the start of your trip.
- On buses and trams, card payment is available via Tap and Go on many ATAC vehicles. A contactless bank card or device can be used directly at the validator.
FAQs: Bus from Santorini (Island) to Rome
Find answers to the most common questions about traveling from Santorini (Island) to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.
Yes, you can take a flight between Santorini (Island) and Rome.
No, the bus from Santorini (Island) to Rome has no accessibility options.
No, there are no bathrooms on board the bus from Santorini (Island) to Rome.
Some of the most interesting sights to explore in Rome are:
- Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
- Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
- Roman Forum, the ruins of ancient Rome's center for public life and government
- Pantheon, a well-preserved Roman temple with a striking dome and oculus
- Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.
The best things to do in Rome include:
- Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
- Take a stroll through Villa Borghese, a beautiful park with museums and gardens
- Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
- Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
- Discover the Catacombs, ancient underground burial sites with guided tours.
No, bikes are not allowed on board the bus from Santorini (Island) to Rome.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Santorini (Island) to Rome.
No, luggage for the bus from Santorini (Island) to Rome needs to be booked in addition.
No, there are no additional luggage options for the bus from Santorini (Island) to Rome.
Unfortunately, pets are not allowed on the bus from Santorini (Island) to Rome.
No, there are no USB plugs on board the bus from Santorini (Island) to Rome.
No, there is no WiFi on board the bus from Santorini (Island) to Rome.
Since both Santorini (Island) and Rome are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Santorini (Island) to Rome among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Rome, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, major landmarks, and popular squares. Common scams include unofficial taxi drivers overcharging and street vendors selling counterfeit goods. It's advisable to use authorized taxis, keep valuables secure, and be wary of distraction techniques used by scammers in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
More options for your journey from Santorini (Island) to Rome
Here are some other resources that might have the information you need
Most popular buses to and from Rome and Santorini (Island)
Most popular bus connections to Rome
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