- Must visit
Royal Museums of Fine Arts of Belgium
Major museum complex with Old Masters, Magritte works, and Belgian art; one of the city’s essential cultural visits.
Cheapest price
$117
Average price
$122
Fastest journey
1 d 4 h 10 m
Average duration
1 d 4 h 18 m
Buses per day
2
Distance
1318 km
The best way to find a cheap bus ticket from Santiago de Compostela to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santiago de Compostela to Brussels will cost around $122 if you buy it on the day, but the cheapest tickets can be found for only $117.
It's difficult to get from Santiago de Compostela to Brussels without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Santiago de Compostela to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $82. For those with little time consider booking a flight which can get you there in 3h 12m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.3kg. The ticket price range depends on the travel mode: a bus costs an average of $82, and a train costs an average of $583.
Distance: 818 miles (1318 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$151 Average price Cheapest | $246 Average price | $583 Average price | $358 Average price (fuel + tolls) |
24h 53m Average total duration 24h 23m Onboard + 30m Additional time* | 6h 12m Average total duration Fastest 3h 12m Onboard + 3h 0m Additional time* | 26h 10m Average total duration 25h 40m Onboard + 30m Additional time* | 17h 50m Average total duration (door-to-door) |
1.3 - 3.3kg CO2 emissions Lowest | 4.0 - 7.9kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Santiago de Compostela to Brussels:
A bus is $95 (€77) less than a flight for this route with tickets for a flight from Santiago de Compostela to Brussels costing on average $246 (€199).
A bus is $432 (€349) less than a train for this route with tickets for a train from Santiago de Compostela to Brussels costing on average $583 (€471).
Other travel options to Brussels take longer:
Bus takes on average 24h 23m.
Train takes on average 25h 40m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:25AM | Arrival Time 01:40PM | Duration 26h15 | Departure days Everyday | Cheapest price $117 |
Operator BlaBlaCar Bus | Departure Time 12:50PM | Arrival Time 01:30PM | Duration 24h40 | Departure days Thu, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 08:15AM | Duration 39h10 | Departure days Wed | Cheapest price $211 |
The table below shows live departures for Santiago de Compostela to Brussels buses for tomorrow, Tuesday, June 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:25 AM Santiago de Compostela, Estación de Autobuses | 28h10 | 3:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 11:25 AM Santiago de Compostela, Estación de Autobuses | 28h25 | 3:50 PM Brussels, Gare Du Midi | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santiago de Compostela to Brussels run on average 3 times per day, taking around 24h 23m. Cheap bus tickets for this journey start at $82 (€66) but you can travel from only $29 (€23) by flight.
The earliest bus runs at 03:15, the last at 22:55. The fastest bus covers the 818 miles (1318 km) distance in 24h 40m.
Distance 818 miles (1318 km) |
Average bus duration 24h 23m |
Cheapest ticket price $82 (€66) |
Buses per day 3 |
Fastest bus 24h 40m |
First bus 3:15 AM |
Last bus 10:55 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 63 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Major museum complex with Old Masters, Magritte works, and Belgian art; one of the city’s essential cultural visits.
Dedicated to René Magritte, with the world’s largest collection of his surrealist works in a central historic setting.
Celebrated museum in an Art Nouveau building, known for its global instrument collection and audio-guided displays.
Popular cultural hill and viewpoint linking the upper and lower city, especially photogenic at sunset.
Historic covered arcade of elegant passages, shops, and architecture, often highlighted in social media imagery.
Stylish square known for antiques, refined atmosphere, and easy access to nearby churches and museums.
Brussels classic of mussels steamed with white wine, celery, onions, or cream, served with crisp fries. It is one of the city’s most iconic comfort dishes.
Traditional Belgian beef and onion stew slowly cooked with dark beer, often slightly sweet-sour and served with fries or bread. A staple in Brussels brasseries.
Rustic mashed potatoes mixed with vegetables such as carrots, leeks, or spinach, often served with sausage or meat. The base preparation is a classic local side dish.
One of Brussels’ most famous fine-dining restaurants, celebrated for refined Belgian and French cuisine in an elegant Art Nouveau setting.
Respected restaurant specializing in carefully prepared Belgian cuisine and strong beer pairings, with a cozy, polished brasserie feel.
Well-known old-school restaurant serving generous Belgian specialties such as carbonnade, stoemp, and sausage in a rustic, bustling atmosphere.
Moderate by Western European standards. Food and transport are manageable, but central hotels cost more.
Service is usually included. Rounding up or leaving 5-10% for great restaurant service is appreciated, not required. Round up taxi fares; no tip is expected for bars or cafés.
Official public transport app
Brussels South (Gare du Midi), Brussels -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Santiago de Compostela to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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