- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price
$91
Average price
$105
Fastest journey
1 d 5 h 10 m
Average duration
1 d 5 h 10 m
Buses per day
2
Distance
1643 km
The best way to find a cheap bus ticket from Santarém to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santarém to Brussels will cost around $105 if you buy it on the day, but the cheapest tickets can be found for only $91.
Of the 2 buses that leave Santarém for Brussels on Sun, Jul 19, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jul 19 the direct buses cover the 1643 km distance in an average of 1 d 5 h 10 m but if you time it right, some buses will get you there in just 1 d 5 h 10 m .
On Sun, Jul 19 the slowest buses will take 1 d 5 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Santarém to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $91. For those with little time consider booking a flight which can get you there in 3h 23m. The ticket price range depends on the travel mode: a bus costs an average of $91, and a flight costs an average of $83.
Distance: 1020 miles (1643 km)
Most popular Bus | Flight |
|---|---|
$138 Average price Cheapest | $258 Average price |
31h 15m Average total duration 30h 45m Onboard + 30m Additional time* | 6h 23m Average total duration Fastest 3h 23m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
This is compared to other travel options from Santarém to Brussels:
A bus is $120 (€98) less than a flight for this route with tickets for a flight from Santarém to Brussels costing on average $258 (€212).
Other travel options to Brussels take longer:
Bus takes on average 30h 45m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:00AM | Arrival Time 01:45PM | Duration 31h45 | Departure days Thu | Cheapest price $160 |
Operator BlaBlaCar Bus | Departure Time 07:00AM | Arrival Time 12:10PM | Duration 29h10 | Departure days Fri, Sun | Cheapest price $118 |
Operator BlaBlaCar Bus | Departure Time 08:00AM | Arrival Time 01:10PM | Duration 29h10 | Departure days Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 11:10PM | Duration 37h30 | Departure days Mon | Cheapest price $178 |
Operator FlixBus | Departure Time 07:45PM | Arrival Time 01:50PM | Duration 42h05 | Departure days Wed | Cheapest price $184 |
The table below shows live departures for Santarém to Brussels buses for tomorrow, Sunday, July 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:00 AM Santarém | 29h10 | 12:10 PM Brussels | 0 transfersDirect | |
![]() | 8:00 AM Santarém | 29h10 | 1:10 PM Brussels | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santarém to Brussels run on average 4 times per day, taking around 30h 45m. Cheap bus tickets for this journey start at $91 (€75) but you can travel from only $83 (€68) by flight.
There are 1 buses per day. The earliest bus runs at 00:45, the last at 22:55. The fastest bus covers the 1020 miles (1643 km) distance in 29h 10m.
Distance 1020 miles (1643 km) |
Average bus duration 30h 45m |
Cheapest ticket price $91 (€75) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 29h 10m |
First bus 12:45 AM |
Last bus 10:55 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Sun |
Least Busy Day Sun |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Santarém to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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