The cheapest and fastest buses from Santarém to Brussels
Cheapest price
$120
Average price
$133
Fastest journey
1 d 7 h 30 m
Average duration
1 d 7 h 38 m
Buses per day
2
Distance
1643 km
The best way to find a cheap bus ticket from Santarém to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santarém to Brussels will cost around $133 if you buy it on the day, but the cheapest tickets can be found for only $120.
It's difficult to get from Santarém to Brussels without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare bus and flight for Santarém to Brussels
Omio recommends booking the bus as it is the most popular option from Santarém to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €86. For those with little time consider booking a flight which can get you there in 3h 28m. The ticket price range depends on the travel mode: a bus costs an average of €86, and a flight costs an average of €54.
Distance: 1020 miles (1643 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€127 Average price Cheapest | €199 Average price |
30h 48m Average total duration 30h 18m Onboard + 30m Additional time* | 6h 28m Average total duration Fastest 3h 28m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Santarém to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:05AM | Arrival Time 03:50PM | Duration 31h45 | Departure days Tue | Cheapest price $120 |
Operator BlaBlaCar Bus | Departure Time 08:00AM | Arrival Time 02:25PM | Duration 29h25 | Departure days Wed | Cheapest price $99 |
Compare prices and tickets Santarém to Brussels by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 25
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Dec 01
Journey information
Overview: Bus from Santarém to Brussels
Buses from Santarém to Brussels run on average 5 times per day, taking around 30h 18m. Cheap bus tickets for this journey start at $106 (€86) but you can travel from only $66 (€54) by flight.
The earliest bus runs at 00:45, the last at 22:55. The fastest bus covers the 1020 miles (1643 km) distance in 29h 25m.
Distance 1020 miles (1643 km) |
Average bus duration 30h 18m |
Cheapest ticket price $106 (€86) |
Buses per day 5 |
Fastest bus 29h 25m |
First bus 00:45 |
Last bus 22:55 |
Bus providers: FlixBus, Alsa, BlaBlaCar Bus from Santarém to BrusselsYou can travel by bus between Santarém to Brussels with FlixBus, Alsa, BlaBlaCar Bus for as low as $66 (€54). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Alsa
BlaBlaCar Bus
FAQs: Bus from Santarém to Brussels
Find answers to the most common questions about traveling from Santarém to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
To find the cheapest bus tickets for your trip from Santarém to Brussels, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Alsa
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Alsa
- Small pets allowed in carriers
- Larger pets must travel in the hold.
popular bus stations
Popular bus stations from Santarém to Brussels
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
Most popular bus connections from Santarém
More options for your journey from Santarém to Brussels
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