The cheapest and fastest buses from Santarém to Brussels
Cheapest price
$52
Average price
$52
Fastest journey
1 d 18 h 5 m
Average duration
1 d 18 h 5 m
Buses per day
1
Distance
1643 km
The best way to find a cheap bus ticket from Santarém to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santarém to Brussels will cost around $52 if you buy it on the day, but the cheapest tickets can be found for only $52.
Of the 1 buses that leave Santarém for Brussels on Mon, Mar 02, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 02 the direct buses cover the 1643 km distance in an average of 1 d 18 h 5 m but if you time it right, some buses will get you there in just 1 d 18 h 5 m .
On Mon, Mar 02 the slowest buses will take 1 d 18 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Santarém to Brussels
Omio recommends booking the bus as it is the most popular option from Santarém to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $52. For those with little time consider booking a flight which can get you there in 3h 23m. The ticket price range depends on the travel mode: a bus costs an average of $52, and a flight costs an average of $38.
Distance: 1020 miles (1643 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$93 Average price Cheapest | $122 Average price |
31h 15m Average total duration 30h 45m Onboard + 30m Additional time* | 6h 23m Average total duration Fastest 3h 23m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Live departures
Santarém to Brussels bus times
The table below shows live departures for Santarém to Brussels buses for today, Sunday, March 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:00 AM Santarém | 29h10 | 1:10 PM Brussels | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santarém to Brussels by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Why should you book Santarém to Brussels buses with Omio?
Why book with Omio vs BlaBlaCar Bus?
- Compare with other providers: On Omio, you can not only buy tickets for BlaBlaCar Bus, but also compare tickets for the likes of FlixBus or Alsa to find the best option for your trip from Santarém to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare BlaBlaCar Bus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Santarém to Brussels.
Why book with Omio over Checkmybus, Wanderu or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or Alsa to find the best option for your trip from Santarém to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Santarém to Brussels.
Journey information
Overview: Bus from Santarém to Brussels
Buses from Santarém to Brussels run on average 4 times per day, taking around 30h 45m. Cheap bus tickets for this journey start at $52 (€41) but you can travel from only $38 (€30) by flight.
There are 1 buses per day. The earliest bus runs at 00:45, the last at 22:55. The fastest bus covers the 1020 miles (1643 km) distance in 29h 10m.
Distance 1020 miles (1643 km) |
Average bus duration 30h 45m |
Cheapest ticket price $52 (€41) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 29h 10m |
First bus 00:45 |
Last bus 22:55 |
Bus providers: BlaBlaCar Bus, FlixBus, Alsa from Santarém to BrusselsYou can travel by bus between Santarém to Brussels with BlaBlaCar Bus, FlixBus, Alsa for as low as $38 (€30). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Alsa
BlaBlaCar Bus
FAQs: Bus from Santarém to Brussels
Find answers to the most common questions about traveling from Santarém to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Alsa
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Santarém to Brussels
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
Most popular bus connections from Santarém
More options for your journey from Santarém to Brussels
Here are some other resources that might have the information you need


