- Recommended
Jack and Shanaz Langson Institute and Museum of California Art
Orange County’s leading contemporary art museum, presenting rotating exhibitions and acclaimed modern artists near UC Irvine.
The best way to find a cheap bus ticket from San Luis Obispo, CA to Irvine, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Luis Obispo, CA to Irvine, CA will cost around €49 if you buy it on the day, but the cheapest tickets can be found for only €49.
It's difficult to get from San Luis Obispo, CA to Irvine, CA without transferring at least once.
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Buses from San Luis Obispo, CA to Irvine, CA run on average 2 times per day, taking around 5h 52m. Cheap bus tickets for this journey start at €34 if you book in advance.
The earliest bus runs at 03:45, the last at 23:30. The fastest bus covers the 196 miles (316 km) distance in 5h 30m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Luis Obispo, CA to Irvine, CA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 10:45AM | Arrival Time 05:11PM | Duration 6h26 | Departure days Fri | Cheapest price €138 |
Operator Amtrak | Departure Time 11:30AM | Arrival Time 05:11PM | Duration 5h41 | Departure days Fri | Cheapest price €133 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 10:00PM | Duration 10h00 | Departure days Wed | Cheapest price €49 |
Operator Amtrak | Departure Time 04:00PM | Arrival Time 02:11AM | Duration 10h11 | Departure days Mon | Cheapest price €91 |
Operator FlixBus | Departure Time 07:05PM | Arrival Time 04:40AM | Duration 9h35 | Departure days Mon, Tue, Thu | Cheapest price €77 |
Operator FlixBus | Departure Time 08:55PM | Arrival Time 05:40AM | Duration 8h45 | Departure days Tue, Thu | Cheapest price €61 |
The table below shows live departures for San Luis Obispo, CA to Irvine, CA buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:05 PM San Luis Obispo, CA | 9h35 | 4:40 AM Irvine, CA | 0 transfersDirect | |
![]() | 8:55 PM San Luis Obispo, CA | 8h45 | 5:40 AM Irvine, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from San Luis Obispo, CA to Irvine, CA with FlixBus. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Irvine, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Irvine, CA trip today.
Orange County’s leading contemporary art museum, presenting rotating exhibitions and acclaimed modern artists near UC Irvine.
University art museum featuring exhibitions of contemporary and historical works, with thought-provoking programs and free admission.
Historic farm site with interpretive exhibits, original structures, and programs that bring Orange County’s agricultural past to life.
Major civic park with trails, sports areas, art spaces, and the iconic balloon, popular with both visitors and locals.
Lakeside shopping and entertainment district with landscaped plazas and a lively pedestrian setting day and night.
Circular park at the heart of UC Irvine with mature trees and paths, ideal for walking, picnics, and campus atmosphere.
Fish tacos are a Southern California staple: battered or grilled fish in corn tortillas with cabbage, crema, and salsa. They reflect the region’s Baja and coastal influence.
California rolls were popularized in Southern California sushi culture. Crab, avocado, and cucumber make them approachable and iconic to the region’s Japanese influence.
Avocado toast is a modern California café classic. Fresh avocado on artisan bread showcases the state’s produce culture and everyday brunch habits.
Established Japanese restaurant in Diamond Jamboree known for quality sushi, izakaya dishes, and a polished yet comfortable setting.
Well-known upscale-casual venue serving seasonal Californian cuisine. Stylish room and dependable service make it a strong fine dining option.
Highly regarded Taiwanese bakery café famous for sea salt coffee, breads, and desserts. Casual, busy, and representative of Irvine’s café culture.
Irvine is pricier than many US cities, with higher hotel and dining costs. Transit is limited, so visitors often need taxis or rental cars, raising daily spend.
Tip 18-20% at restaurants, 15-20% for taxis and rideshares, and $1-2 per drink or coffee is appreciated.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Irvine, CA.
Find answers to the most common questions about traveling from San Luis Obispo, CA to Irvine, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Irvine, CA, this guide helps you travel smarter and with confidence.

Most San Luis Obispo, CA to Irvine, CA buses use the San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) to station pair. Use this guide to compare San Luis Obispo, CA and Irvine, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) is 1 km from San Luis Obispo city centre. Public transport options include:
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum). ATMs are available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum).
Ticket office support is available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum).
Available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum): Parking, Taxis, WC.
Accessibility facilities are available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum): Basic accessibility features available.