- Must visit
Edison and Ford Winter Estates
Historic estate complex with museum galleries on Thomas Edison and Henry Ford, period homes, gardens, and a laboratory. One of Fort Myers' signature cultural attractions.
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The cheapest and fastest buses from San Antonio, TX to Fort Myers, FL
Showing times and prices for Jun 01
Cheapest price
$312
Average price
$312
Fastest journey
2 d 1 h 35 m
Average duration
2 d 1 h 35 m
Buses per day
1
Distance
1663 km
Cheap tickets
The best way to find a cheap bus ticket from San Antonio, TX to Fort Myers, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Fort Myers, FL will cost around $312 if you buy it on the day, but the cheapest tickets can be found for only $312.
Fast buses
Of the 1 buses that leave San Antonio, TX for Fort Myers, FL on Mon, Jun 01, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 01 the direct buses cover the 1663 km distance in an average of 2 d 1 h 35 m but if you time it right, some buses will get you there in just 2 d 1 h 35 m .
On Mon, Jun 01 the slowest buses will take 2 d 1 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:45 PM49h35San Antonio, TX2:20 PMFort Myers, FL$3121One-way0 transfers
- 12:45 PM49h35San Antonio, TX2:20 PMFort Myers, FL$3121One-way0 transfers
Travel Information
Compare bus, train, and flight for San Antonio, TX to Fort Myers, FL
Omio recommends booking the bus as it is the most popular option from San Antonio, TX to Fort Myers, FL among Omio's users. If you are prioritising price take the bus with prices starting from $279. For those with little time consider booking a flight which can get you there in 7h 8m. The ticket price range depends on the travel mode: a bus costs an average of $279, and a train costs an average of $573.
Distance: 1033 miles (1663 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$300 Average price Cheapest | $1147 Average price | $579 Average price | $260 Average price (fuel + tolls) |
27h 49m Average total duration 27h 19m Onboard + 30m Additional time* | 82h 12m Average total duration 81h 42m Onboard + 30m Additional time* | 10h 8m Average total duration Fastest 7h 8m Onboard + 3h 0m Additional time* | 18h 33m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from San Antonio, TX to Fort Myers, FL is a bus with an average price of $300 (€241).
This is compared to other travel options from San Antonio, TX to Fort Myers, FL:
A bus is $279 (€225) less than a flight for this route with tickets for a flight from San Antonio, TX to Fort Myers, FL costing on average $579 (€466).
A bus is $847 (€682) less than a train for this route with tickets for a train from San Antonio, TX to Fort Myers, FL costing on average $1147 (€923).
The fastest way to travel from San Antonio, TX to Fort Myers, FL is by flight with an average journey time of 7h 8m.
Other travel options to Fort Myers, FL take longer:
Bus takes on average 27h 19m.
Train takes on average 81h 42m.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Fort Myers, FL including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from San Antonio, TX to Fort Myers, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Antonio, TX to Fort Myers, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45PM | Arrival Time 02:20PM | Duration 49h35 | Departure days Mon, Fri, Sat, Sun | Cheapest price $279 |
Live departures
San Antonio, TX to Fort Myers, FL bus times
The table below shows live departures for San Antonio, TX to Fort Myers, FL buses for tomorrow, Monday, June 1. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:45 PM San Antonio, TX | 49h35 | 2:20 PM Fort Myers, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Antonio, TX to Fort Myers, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book San Antonio, TX to Fort Myers, FL buses with Omio?
Greyhound operates all buses services from San Antonio, TX to Fort Myers, FL.
Omio is an official ticket reseller for all your travel options from San Antonio, TX to Fort Myers, FL.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from San Antonio, TX to Fort Myers, FL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from San Antonio, TX to Fort Myers, FL.
Journey information
Overview: Bus from San Antonio, TX to Fort Myers, FL
USAUSA
Buses from San Antonio, TX to Fort Myers, FL run on average 8 times per day, taking around 27h 19m. Cheap bus tickets for this journey start at $279 (€225) if you book in advance.
The earliest bus runs at 01:05, the last at 21:15. The fastest bus covers the 1033 miles (1663 km) distance in 49h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1033 miles (1663 km) |
Average bus duration 27h 19m |
Cheapest ticket price $279 (€225) |
Buses per day 8 |
Fastest bus 49h 35m |
First bus 1:05 AM |
Last bus 9:15 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from San Antonio, TX to Fort Myers, FLYou can travel by bus between San Antonio, TX to Fort Myers, FL with Greyhound for as low as $279 (€225). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
40h 40m
Cheapest Price
$410 (€330)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Fort Myers
Things to do in Fort Myers
Discover the best of Fort Myers — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Fort Myers trip today.
- Recommended
IMAG History & Science Center
Family-friendly science and local history museum with hands-on exhibits, aquariums, and regional ecology displays. Popular for interactive indoor visits.
- Recommended
Sidney & Berne Davis Art Center
Downtown visual arts venue in a restored historic building, hosting exhibitions, cultural programming, and community arts events.
- Must visit
Fort Myers River District
Historic downtown core with brick streets, murals, shops, galleries, and nightlife. The city's main walking district and a top place to explore.
- Recommended
Centennial Park
Waterfront downtown park along the Caloosahatchee River with open lawns, event space, and views toward the bridge and river traffic.
- Recommended
McGregor Boulevard
Scenic palm-lined corridor strongly associated with Fort Myers history, especially the route toward the Edison and Ford estates.
Grouper Sandwich
A Florida Gulf Coast staple made with fresh local grouper, usually grilled, blackened, or fried on a bun. It is one of the most recognizable seafood dishes in Southwest Florida.
- Gluten-free
Stone Crab Claws
Seasonal Florida stone crab claws are served chilled with mustard sauce. They are prized across coastal Florida for their sweet, firm meat.
Conch Fritters
A popular Florida and Caribbean-influenced snack of chopped conch in seasoned batter, deep-fried and served with dipping sauce. Common on seafood menus in the area.
Roadhouse Cafe
An established upscale restaurant recognized for polished service, steaks, seafood, and live jazz. It offers a more refined dinner experience.
The Veranda
A long-running fine dining restaurant in historic downtown Fort Myers, known for Southern-influenced cuisine, seafood, and elegant old-Florida atmosphere.
Doc Ford's Rum Bar & Grille
A well-known casual restaurant popular for seafood, Caribbean-inspired dishes, and rum drinks. It is a reliable local favorite with a lively waterfront Florida feel.
United States Dollar
Moderate by U.S. standards. Casual dining is reasonable, but beach areas, resorts, and seasonal stays cost more.
Average meal costs
- Budget
- USD 10-18 for fast food or a simple lunch.
- Mid-range
- USD 20-40 per person at a casual sit-down restaurant.
- Fine dining
- USD 60-120+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis and rideshares: 10-15%. Hotel staff: USD 2-5. Not expected for fast food.
FAQs: Bus from San Antonio, TX to Fort Myers, FL
Find answers to the most common questions about traveling from San Antonio, TX to Fort Myers, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Antonio, TX to Fort Myers, FL can start from as little as $279 (€225) when you book in advance. The average bus ticket price for San Antonio, TX to Fort Myers, FL is $300 (€241) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Antonio, TX to Fort Myers, FL is 49h 35m to travel the 1033 miles (1663 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Antonio, TX to Fort Myers, FL leaves at 1:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Antonio, TX to Fort Myers, FL leaves at 9:15 PM.
There are 8 buses a day from San Antonio, TX to Fort Myers, FL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Antonio, TX to Fort Myers, FL, you can count on Greyhound for the best way to get you to Fort Myers, FL. You can also check all possible bus companies who offer a service between San Antonio, TX and Fort Myers, FL and compare the amenities they offer before buying a bus ticket.
A trip to Fort Myers, FL from San Antonio, TX is worth doing but not as a day trip with a journey time of 49h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Antonio, TX to Fort Myers, FL is September.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Fort Myers, FL including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from San Antonio, TX to Fort Myers, FL for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from San Antonio, TX to Fort Myers, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from San Antonio, TX to Fort Myers, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Antonio, TX to Fort Myers, FL.
Yes, the following luggage options are included when booking a bus ticket from San Antonio, TX to Fort Myers, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Antonio, TX to Fort Myers, FL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Antonio, TX to Fort Myers, FL.
You can reserve your seat on the bus from San Antonio, TX to Fort Myers, FL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Antonio, TX to Fort Myers, FL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Antonio, TX to Fort Myers, FL with the following bus company: Greyhound.
Since neither San Antonio, TX nor Fort Myers, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from San Antonio, TX to Fort Myers, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Fort Myers, FL, travelers should be cautious of petty theft, especially in crowded areas and on beaches. Common scams include overcharging by taxis or ride services and timeshare presentations that pressure visitors into high-cost deals. It's advisable to use official transportation options, keep valuables secure, and remain aware of surroundings to ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from San Antonio, TX to Fort Myers, FL
San Antonio
Fort Myers
The major bus station for departures in San Antonio is San Antonio, N St Mary's St (Greyhound). Find all the information you need to know about services, amenities and connections at San Antonio, N St Mary's St (Greyhound) for your trip from San Antonio to Fort Myers.
San Antonio, N St Mary's St (Greyhound)
information
San Antonio, Avenue A / Pearl Pkwy
information
The major bus station for arrivals in Fort Myers is Fort Myers, Rosa Parks Transit Center. Find all the information you need to know about services, amenities and connections at Fort Myers, Rosa Parks Transit Center for your trip to Fort Myers from San Antonio.
Fort Myers, Rosa Parks Transit Center
information
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Fort Myers, FL
Here are some other resources that might have the information you need
Most popular buses to and from Fort Myers, FL and San Antonio, TX
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