Why should you book San Antonio, TX to Fort Myers, FL buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from San Antonio, TX to Fort Myers, FL
Take a bus from San Antonio, TX to Fort Myers, FL and enjoy the approximately 1033 miles (1663 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 01:05, the last at 21:15.
Distance 1033 miles (1663 km) |
Average bus duration 27h 19m |
Buses per day 7 |
First bus 01:05 |
Last bus 21:15 |
Bus providers: Greyhound from San Antonio, TX to Fort Myers, FLYou can travel by bus between San Antonio, TX to Fort Myers, FL with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Antonio, TX to Fort Myers, FL
Find answers to the most common questions about traveling from San Antonio, TX to Fort Myers, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Antonio, TX to Fort Myers, FL
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Fort Myers, FL
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