- Must visit
Museo Archeologico Regionale Paolo Orsi
Important museum in Syracuse focused on Greek and Roman Sicily, with statues, sarcophagi, and archaeological discoveries from the area.
Cheapest price on Oct 12
CHF40
Average ticket price on Oct 12
CHF40
Fastest journey on Oct 12
11 h 35 m
Average journey duration on Oct 12
11 h 45 m
Buses on Oct 12
2
Distance
501 km
The best way to find a cheap bus ticket from Rome to Sicily (Island) is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Sicily (Island) will cost around CHF40 if you buy it on the day, but the cheapest tickets can be found for only CHF40.
On Mon, Oct 12, we found 2 buses from Rome to Sicily (Island), including 2 direct services.
On Mon, Oct 12 the direct buses cover the 501 km distance in an average of 11 h 45 m but if you time it right, some buses will get you there in just 11 h 35 m .
On Mon, Oct 12 the slowest buses will take 11 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2125
2125
2125
2125Buses from Rome to Sicily (Island) run on average 5 times per day, taking around 13h 23m. Cheap bus tickets for this journey start at CHF13 if you book in advance.
There are 4 buses per day. The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 311 miles (501 km) distance in 11h 25m.
Distance 311 miles (501 km) |
Average bus duration 13h 23m |
Cheapest ticket price CHF13 |
Buses per day 5 |
Direct buses 4 |
Fastest bus 11h 25m |
First bus 1:15 AM |
Last bus 11:30 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Thu |
Best time to book 6 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 04:25PM | Arrival Time 08:50AM | Duration 16h25 | Departure days Thu, Fri, Sat, Sun | Cheapest price CHF23 |
Operator Itabus | Departure Time 07:30PM | Arrival Time 07:25AM | Duration 11h55 | Departure days Everyday | Cheapest price CHF30 |
The table below shows live departures for Rome to Sicily (Island) buses for today, Sunday, October 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
4411 | 4:25 PM Roma, Autostazione Tiburtina | 16h25 | 8:50 AM Catania, Aeroporto di Catania-Fontanarossa (P2 Breve Sosta) | 0 transfersDirect | |
4411 | 4:25 PM Roma, Autostazione Tiburtina | 16h05 | 8:30 AM Catania, Via D'Amico | 0 transfersDirect | |
4411 | 4:25 PM Roma, Autostazione Tiburtina | 15h20 | 7:45 AM Giardini Naxos, Viale Dionisio (Bus Terminal Recanati) | 0 transfersDirect | |
2125 | 7:30 PM Roma, Autostazione Tiburtina | 11h55 | 7:25 AM Catania, Aeroporto di Catania-Fontanarossa (P2 Breve Sosta) | 0 transfersDirect | |
2125 | 7:30 PM Roma, Autostazione Tiburtina | 11h35 | 7:05 AM Catania, Via D'Amico | 0 transfersDirect |
Find all the dates and times for this journey
Discover the best of Sicily (Island) — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Sicily (Island) trip today.
Important museum in Syracuse focused on Greek and Roman Sicily, with statues, sarcophagi, and archaeological discoveries from the area.
Major archaeology museum in Palermo with Phoenician, Greek, and Roman finds, including sculpture, bronzes, and artifacts from across Sicily.
Elegant palace museum in Palermo displaying Sicilian decorative arts, painting, and richly furnished historic rooms near the harbor.
Main square of Ortigia in Syracuse, framed by Baroque buildings and the cathedral, ideal for strolling and soaking up the historic setting.
Lively seafront promenade in Catania facing the Ionian Sea, popular for sunset walks, lava-rock views, and a local evening atmosphere.
Historic market street area in Palermo with narrow lanes, churches, and an energetic everyday atmosphere that reveals the city's character.
Crisp fried rice balls stuffed with ragù, peas and cheese. A hallmark Sicilian street food with regional variations across the island.
Pasta with fried eggplant, tomato, basil and salted ricotta. A classic Catania dish tied to Sicilian produce and simple bold flavors.
Fresh sardines with wild fennel, pine nuts, raisins and saffron, usually served with pasta. It reflects Sicily’s Arab and Mediterranean influences.
Refined seafood-focused dining in Taormina with elegant tasting menus and polished service in a central historic setting.
Historic Palermo street-food institution known for pani ca meusa and classic local snacks in a simple, traditional setting.
Traditional Catania restaurant serving Sicilian home-style dishes, seafood and local specialties in a warm, rustic atmosphere.
Moderate for Italy. Prices rise in Taormina and peak summer, but many Sicilian towns still offer good-value stays, meals, and regional trains or buses.
Service may be included as coperto. Restaurants: round up or leave 5-10% for great service. Cafes: small change. Taxis: round up to the nearest euro; tipping is appreciated, not required.
Find answers to the most common questions about traveling from Rome to Sicily (Island) by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Sicily (Island), this guide helps you travel smarter and with confidence.

Most Rome to Sicily (Island) buses use the Roma, Autostazione Tiburtina to Catania, Via D'Amico station pair, with some services arriving at Enna, Via Leonardo da Vinci (Bassa). Use this guide to compare Rome and Sicily (Island) bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Enna, Via Leonardo da Vinci (Bassa) is 1 km from Sicily city centre. Public transport options include:
Enna, Via Leonardo da Vinci (Bassa) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Enna, Via Leonardo da Vinci (Bassa). ATMs are available at Enna, Via Leonardo da Vinci (Bassa).
Ticket office support is available at Enna, Via Leonardo da Vinci (Bassa).
Available at Enna, Via Leonardo da Vinci (Bassa): Parking, Taxis, WC.
Accessibility facilities are available at Enna, Via Leonardo da Vinci (Bassa): Limited accessibility features.
Caltanissetta, Via Rochester (Autostazione) is 1 km from Sicily city centre. Public transport options include:
Caltanissetta, Via Rochester (Autostazione) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Caltanissetta, Via Rochester (Autostazione). ATMs are available at Caltanissetta, Via Rochester (Autostazione).
Ticket office support is available at Caltanissetta, Via Rochester (Autostazione).
Available at Caltanissetta, Via Rochester (Autostazione): Parking, Taxis, WC.
Accessibility facilities are available at Caltanissetta, Via Rochester (Autostazione): Basic accessibility features available.
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