The cheapest and fastest buses from Rome to Sicily (Island)
Cheapest price
$51
Average price
$51
Fastest journey
11 h 55 m
Average duration
14 h 38 m
Buses per day
3
Distance
501 km
The best way to find a cheap bus ticket from Rome to Sicily (Island) is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Sicily (Island) will cost around $51 if you buy it on the day, but the cheapest tickets can be found for only $51.
Of the 3 buses that leave Rome for Sicily (Island) on Fri, Feb 27, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 27 the direct buses cover the 501 km distance in an average of 14 h 38 m but if you time it right, some buses will get you there in just 11 h 55 m .
On Fri, Feb 27 the slowest buses will take 16 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare train, bus, flight, and ferry for Rome to Sicily (Island)
Omio recommends booking the flight as it is the most popular option from Rome to Sicily (Island) among Omio's users. If you are prioritising price take the bus with prices starting from $23. For those with little time consider booking a flight which can get you there in 1h 16m. The ticket price range depends on the travel mode: a bus costs an average of $23, and a flight costs an average of $22.
Distance: 311 miles (501 km)
Compare bus with
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
$55 Average price Cheapest | $148 Average price | $100 Average price | $69 Average price |
13h 52m Average total duration 13h 22m Onboard + 30m Additional time* | 4h 16m Average total duration Fastest 1h 16m Onboard + 3h 0m Additional time* | 11h 5m Average total duration 10h 35m Onboard + 30m Additional time* | 15h 16m Average total duration 14h 16m Onboard + 1h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Rome to Sicily (Island) Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 04:40AM | Arrival Time 03:10PM | Duration 10h30 | Departure days Sat | Cheapest price $99 |
Operator Itabus | Departure Time 04:25PM | Arrival Time 08:30AM | Duration 16h05 | Departure days Thu, Sat, Sun | Cheapest price $41 |
Operator Itabus | Departure Time 07:30PM | Arrival Time 07:25AM | Duration 11h55 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $30 |
Live departures
Rome to Sicily (Island) bus times
The table below shows live departures for Rome to Sicily (Island) buses for today, Thursday, February 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
4411 | 3:25 PM Roma, Autostazione Tiburtina | 16h05 | 7:30 AM Catania, Via D'Amico | 0 transfersDirect | |
4411 | 3:25 PM Roma, Autostazione Tiburtina | 16h25 | 7:50 AM Catania, Aeroporto di Catania-Fontanarossa (P2 Breve Sosta) | 0 transfersDirect | |
2125 | 6:30 PM Roma, Autostazione Tiburtina | 11h55 | 6:25 AM Catania, Aeroporto di Catania-Fontanarossa (P2 Breve Sosta) | 0 transfersDirect | |
2125 | 6:30 PM Roma, Autostazione Tiburtina | 11h35 | 6:05 AM Catania, Via D'Amico | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Sicily (Island) by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 26
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
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Mar 07
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Mar 10
Mar 11
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Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Why should you book Rome to Sicily (Island) buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Rome to Sicily (Island).
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Rome to Sicily (Island).
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Rome to Sicily (Island).
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Rome to Sicily (Island).
Journey information
Overview: Bus from Rome to Sicily (Island)
Buses from Rome to Sicily (Island) run on average 12 times per day, taking around 13h 22m. Cheap bus tickets for this journey start at $23 (€18) but you can travel from only $22 (€17) by flight.
There are 5 buses per day. The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 311 miles (501 km) distance in 11h 55m.
Distance 311 miles (501 km) |
Average bus duration 13h 22m |
Cheapest ticket price $23 (€18) |
Buses per day 12 |
Direct buses 5 |
Fastest bus 11h 55m |
First bus 01:15 |
Last bus 23:30 |
Bus providers: FlixBus, Itabus from Rome to Sicily (Island)You can travel by bus between Rome to Sicily (Island) with FlixBus, Itabus for as low as $22 (€17). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
FAQs: Bus from Rome to Sicily (Island)
Find answers to the most common questions about traveling from Rome to Sicily (Island) by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Sicily (Island), this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Rome to Sicily (Island)
- 06:00-23:00
- Free Wi-Fi
- Ristorante Italiano (in the station)
- Fast Food Express (in the station)
- Caffè del Terminal (in the station).
- Available outside the arrivals terminal.
- Elevators, ramps
- Available in the station.
- Bus: 520, 720 Train: Leonardo Express
More options for your journey from Rome to Sicily (Island)
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