- Must visit
Museo Archeologico Regionale Paolo Orsi
One of Italy’s most important archaeological museums, with outstanding collections from prehistoric to Greek and Roman Sicily.
Cheapest price
$62
Average price
$74
Fastest journey
11 h 35 m
Average duration
14 h
Buses per day
4
Distance
501 km
The best way to find a cheap bus ticket from Rome to Sicily (Island) is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Sicily (Island) will cost around $74 if you buy it on the day, but the cheapest tickets can be found for only $62.
Of the 4 buses that leave Rome for Sicily (Island) on Thu, May 28, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct buses cover the 501 km distance in an average of 14 h but if you time it right, some buses will get you there in just 11 h 35 m .
On Thu, May 28 the slowest buses will take 16 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4411
4411
2125
2125
2125
2125
4411
4411Omio recommends booking the flight as it is the most popular option from Rome to Sicily (Island) among Omio's users. If you are prioritising price take the bus with prices starting from $25. For those with little time consider booking a flight which can get you there in 3h 23m. The ticket price range depends on the travel mode: a bus costs an average of $25, and a flight costs an average of $23.
Distance: 311 miles (501 km)
| Bus | Most popular Flight | Train | Ferry | Driving |
|---|---|---|---|---|
$46 Average price Cheapest | $116 Average price | $114 Average price | $70 Average price | $75 Average price (fuel + tolls) |
9h 35m Average total duration 9h 5m Onboard + 30m Additional time* | 6h 23m Average total duration Fastest 3h 23m Onboard + 3h 0m Additional time* | 10h 59m Average total duration 10h 29m Onboard + 30m Additional time* | 15h 16m Average total duration 14h 16m Onboard + 1h 0m Additional time* | 9h 31m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Rome to Sicily (Island):
A bus is $24 (€19) less than a ferry for this route with tickets for a ferry from Rome to Sicily (Island) costing on average $70 (€56).
A bus is $68 (€55) less than a train for this route with tickets for a train from Rome to Sicily (Island) costing on average $114 (€92).
A bus is $70 (€57) less than a flight for this route with tickets for a flight from Rome to Sicily (Island) costing on average $116 (€94).
Other travel options to Sicily (Island) take longer:
Bus takes on average 9h 5m.
Train takes on average 10h 29m.
Ferry takes on average 14h 16m.
You'll arrive about 26m sooner (9h 5m by bus vs 9h 31m by car) and save roughly $29 (€24) compared to fuel and tolls ($46 (€37) vs $75 (€61)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Itabus, FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 12:50AM | Arrival Time 03:30PM | Duration 14h40 | Departure days Sat | Cheapest price $62 |
Operator BlaBlaCar | Departure Time 01:00PM | Arrival Time 01:50AM | Duration 12h50 | Departure days Fri | Cheapest price $96 |
Operator Itabus | Departure Time 04:25PM | Arrival Time 08:50AM | Duration 16h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $37 |
Operator Itabus | Departure Time 07:30PM | Arrival Time 07:05AM | Duration 11h35 | Departure days Everyday | Cheapest price $48 |
The table below shows live departures for Rome to Sicily (Island) buses for today, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
2125 | 7:30 PM Roma, Autostazione Tiburtina | 11h35 | 7:05 AM Catania, Via D'Amico | 0 transfersDirect | |
2125 | 7:30 PM Roma, Autostazione Tiburtina | 11h55 | 7:25 AM Catania, Aeroporto di Catania-Fontanarossa (P2 Breve Sosta) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Rome to Sicily (Island) run on average 10 times per day, taking around 9h 5m. Cheap bus tickets for this journey start at $25 (€20) but you can travel from only $23 (€19) by flight.
There are 5 buses per day. The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 311 miles (501 km) distance in 11h 55m.
Distance 311 miles (501 km) |
Average bus duration 9h 5m |
Cheapest ticket price $25 (€20) |
Buses per day 10 |
Direct buses 5 |
Fastest bus 11h 55m |
First bus 1:15 AM |
Last bus 11:30 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 35 days |
Discover the best of Sicily — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Sicily trip today.
One of Italy’s most important archaeological museums, with outstanding collections from prehistoric to Greek and Roman Sicily.
Main archaeological museum for Agrigento, displaying finds from ancient Akragas and giving essential context before visiting the Valley of the Temples.
Palermo’s leading archaeological museum, known for major Phoenician, Greek, and Roman collections from across Sicily.
Historic island heart of Syracuse, loved for baroque streets, waterfront walks, lively piazzas, and sunset views.
Elegant pedestrian old town with famous viewpoints, boutiques, cafés, and access to some of Sicily’s most shared photo spots.
Famous white marl cliff near Realmonte, highly popular online for its dramatic coastal scenery and sunset photos.
Stuffed rice balls coated with breadcrumbs and fried, usually filled with ragù, mozzarella, or butter and ham. One of Sicily’s most iconic street foods.
Traditional Sicilian pasta with tomato sauce, fried eggplant, basil, and salted ricotta. A classic Catania dish loved across the island.
Sweet-and-sour eggplant dish with tomato, celery, olives, and capers. Served as an antipasto or side and deeply rooted in Sicilian home cooking.
Refined Michelin-starred restaurant in Licata led by chef Pino Cuttaia, celebrated for creative interpretations of Sicilian ingredients and traditions.
Beloved Catania pastry shop known for arancini, cannoli, granita, and other Sicilian sweets and snacks. Busy, classic, and very well established.
Well-known Syracuse osteria serving traditional Sicilian seafood and pasta dishes in a relaxed historic-center atmosphere.
Moderate overall. Street food and local trattorias are good value, while resorts, islands, and tourist hotspots cost more.
Service is often included or modest. Tipping is not required, but rounding up or leaving 5-10% for good service is appreciated. Round up taxis; small tips for hotel staff are welcome.
Find answers to the most common questions about traveling from Rome to Sicily (Island) by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Sicily (Island), this guide helps you travel smarter and with confidence.

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