- Recommended
Valley of the Temples Archaeological Museum "Pietro Griffo"
Main archaeological museum for Agrigento, displaying finds from Akragas and providing essential context before visiting the temple park.




Cheapest price
$49
Average price
$50
Fastest journey
11h 35m
Average duration
14h 0m
Buses per day
4
Distance
536 km
Omio recommends booking the flight as it is the most popular option from Rome to Sicily (Island) among Omio's users. If you are prioritising price take the bus with prices starting from $25. For those with little time consider booking a flight which can get you there in 3h 23m. The ticket price range depends on the travel mode: a bus costs an average of $25, and a flight costs an average of $23.
Distance: 311 miles (501 km)
| Bus | Most popular Flight | Train | Ferry | Driving |
|---|---|---|---|---|
$45 Average price Cheapest | $114 Average price | $112 Average price | $68 Average price | $74 Average price (fuel + tolls) |
9h 35m Average total duration 9h 5m Onboard + 30m Additional time* | 6h 23m Average total duration Fastest 3h 23m Onboard + 3h 0m Additional time* | 10h 59m Average total duration 10h 29m Onboard + 30m Additional time* | 15h 16m Average total duration 14h 16m Onboard + 1h 0m Additional time* | 9h 31m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Rome to Sicily (Island):
A bus is $23 (€19) less than a ferry for this route with tickets for a ferry from Rome to Sicily (Island) costing on average $68 (€56).
A bus is $67 (€55) less than a train for this route with tickets for a train from Rome to Sicily (Island) costing on average $112 (€92).
A bus is $69 (€57) less than a flight for this route with tickets for a flight from Rome to Sicily (Island) costing on average $114 (€94).
Other travel options to Sicily (Island) take longer:
Bus takes on average 9h 5m.
Train takes on average 10h 29m.
Ferry takes on average 14h 16m.
You'll arrive about 26m sooner (9h 5m by bus vs 9h 31m by car) and save roughly $29 (€24) compared to fuel and tolls ($45 (€37) vs $74 (€61)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Itabus, FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 09:00AM | Arrival Time 09:05PM | Duration 12h05 | Departure days Thu, Fri | Cheapest price $52 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 10:00PM | Duration 11h00 | Departure days Sun | Cheapest price $77 |
Operator Itabus | Departure Time 04:25PM | Arrival Time 08:30AM | Duration 16h05 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $47 |
Operator Itabus | Departure Time 06:15PM | Arrival Time 06:45AM | Duration 12h30 | Departure days Thu, Fri | Cheapest price $30 |
Operator Itabus | Departure Time 07:30PM | Arrival Time 07:05AM | Duration 11h35 | Departure days Everyday | Cheapest price $43 |
The table below shows live departures for Rome to Sicily (Island) buses for today, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
4411 | 4:25 PM Roma, Autostazione Tiburtina | 16h05 | 8:30 AM Catania, Via D'Amico | 0 transfersDirect | |
4411 | 4:25 PM Roma, Autostazione Tiburtina | 16h25 | 8:50 AM Catania, Aeroporto di Catania-Fontanarossa (P2 Breve Sosta) | 0 transfersDirect | |
2125 | 7:30 PM Roma, Autostazione Tiburtina | 11h35 | 7:05 AM Catania, Via D'Amico | 0 transfersDirect | |
2125 | 7:30 PM Roma, Autostazione Tiburtina | 11h55 | 7:25 AM Catania, Aeroporto di Catania-Fontanarossa (P2 Breve Sosta) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Rome to Sicily (Island) run on average 10 times per day, taking around 9h 5m. Cheap bus tickets for this journey start at $25 (€20) but you can travel from only $23 (€19) by flight.
There are 5 buses per day. The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 311 miles (501 km) distance in 11h 55m.
Distance 311 miles (501 km) |
Average bus duration 9h 5m |
Cheapest ticket price $25 (€20) |
Buses per day 10 |
Direct buses 5 |
Fastest bus 11h 55m |
First bus 1:15 AM |
Last bus 11:30 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 35 days |
Discover the best of Sicily — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Sicily trip today.
Main archaeological museum for Agrigento, displaying finds from Akragas and providing essential context before visiting the temple park.
Major Palermo gallery in a Gothic-Catalan palace, best known for Antonello da Messina and important Sicilian medieval and Renaissance art.
One of Sicily's leading archaeological museums, with Punic, Greek and Roman collections in central Palermo.
Syracuse's atmospheric old island center, packed with baroque streets, waterfront walks and photogenic piazzas.
Taormina's iconic seaside nature spot, linked to the shore by a narrow strip and hugely popular in photos and social media.
Striking white marl cliffs near Realmonte, famous for dramatic coastal views and high visual appeal online.
Fried rice balls stuffed with ragù, mozzarella, or butter and ham. One of Sicily’s most iconic street foods, with local variations across the island.
A classic Catania pasta with tomato, fried eggplant, basil, and salted ricotta. It is one of Sicily’s best-known traditional vegetarian dishes.
Sweet-and-sour eggplant dish with tomato, celery, olives, and capers. Served as an antipasto or side, it reflects Sicily’s Arab and Mediterranean influences.
Acclaimed fine-dining restaurant in Licata offering creative cuisine rooted in Sicilian products, with a sophisticated tasting-menu experience.
Well-known Palermo restaurant serving refined Sicilian dishes with strong local ingredients, combining traditional recipes with a polished atmosphere.
Celebrated Noto pastry and dessert institution, especially known for granita, cannoli, almond sweets, and elegant Sicilian confectionery traditions.
Generally cheaper than Rome or Milan. Food is good value, while resort areas and summer stays cost more.
Service is often included or minimal. Tipping is not required, but rounding up or leaving 5-10% for good service is appreciated. Round up taxi fares slightly.
Find answers to the most common questions about traveling from Rome to Sicily (Island) by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Sicily (Island), this guide helps you travel smarter and with confidence.

Most Rome to Sicily (Island) buses use the Roma, Autostazione Tiburtina to Enna, Via Leonardo da Vinci (Bassa) station pair, with some services arriving at Catania, Via D'Amico. Use this guide to compare Rome and Sicily (Island) bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Here are some other resources that might have the information you need