Travel Information
Compare train, bus, and flight for Rome to San Donato Milanese
Omio recommends booking the bus as it is the most popular option from Rome to San Donato Milanese among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $37 For those with little time, consider booking a flight, which has an average total journey time of 4h 47m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $37, while a flight costs an average of $563.
Distance: 292 miles (470 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$37 Average price Cheapest | $563 Average price | $102 Average price | $167 Average price (fuel + tolls) |
8h 24m Average total duration 7h 54m Onboard + 30m Additional time* | 4h 47m Average total duration Fastest 2h 47m Onboard + 2h 0m Additional time* | 5h 0m Average total duration 4h 30m Onboard + 30m Additional time* | 6h 3m Average total duration (door-to-door) |
0.5 - 1.2kg CO2 emissions | - CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Rome to San Donato Milanese
Compare the available ways to get from Rome to San Donato Milanese, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Rome to San Donato Milanese:
A bus is $65 (€55) less than a train for this route with tickets for a train from Rome to San Donato Milanese costing on average $102 (€86).
A bus is $526 (€441) less than a flight for this route with tickets for a flight from Rome to San Donato Milanese costing on average $563 (€472).
Other travel options to San Donato Milanese take longer:
Train takes on average 5h 0m.
Bus takes on average 8h 24m.
Tickets start at around $37 (€31) compared to roughly $167 (€140) in fuel and tolls — a saving of about $130 (€109). The journey takes 7h 54m versus 6h 3m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Rome to San Donato Milanese
How to get from Rome to San Donato Milanese by train, bus or flight.
Our recommendation
The best way to travel from Rome to San Donato Milanese is by taking a bus because it’s the best combination of price and speed.
24141:00 PM 8h25 Roma, Autostazione Tiburtina 9:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) $14 1 One-way 0 transfers
Cheapest
24141:00 PM 8h25 Roma, Autostazione Tiburtina 9:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) $14 1 One-way 0 transfers
Fastest
Intercity 590+
S1 TRENORD 2416612:43 PM 6h37 Rome Tiburtina 7:20 PM San Donato Milanese station $72 1 One-way 1 transfer
Other options
Regionale Veloce 4134 · Regionale 2296 · S1 TRENORD 241822:12 PM 9h08 Rome Termini 11:20 PM San Donato Milanese station $56 1 One-way 2 transfers
InterCityNotte 798+
S1 TRENORD 24117 · Regionale TRENORD 1085411:51 PM 7h18 Rome Tiburtina 7:09 AM San Donato Milanese station $68 1 One-way 2 transfers
InterCityNotte 794+
Regionale Veloce 3030 · S1 TRENORD 241496:06 AM 9h03 Rome Ostiense 3:09 PM San Donato Milanese station $72 1 One-way 2 transfers
FlixBus10:40 AM 7h50 Roma, Autostazione Tiburtina 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) $21 1 One-way 0 transfers
FlixBus · FlixBus1:05 PM 8h50 Roma, Autostazione (Metro Anagnina) 9:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) $29 1 One-way 1 transfer
2494 · 221410:15 PM 9h20 Roma, Autostazione Tiburtina 7:35 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) $30 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Rome to San Donato Milanese
Travel to San Donato Milanese easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to San Donato Milanese.

This is compared to other travel options from Rome to San Donato Milanese:
A bus is $65 (€55) less than a train for this route with tickets for a train from Rome to San Donato Milanese costing on average $102 (€86).
A bus is $526 (€441) less than a flight for this route with tickets for a flight from Rome to San Donato Milanese costing on average $563 (€472).
Other travel options to San Donato Milanese take longer:
Train takes on average 5h 0m.
Bus takes on average 8h 24m.
- Around 23 flights per day.
- Around 16 trains per day.
- Around 13 buses per day.
However, we recommend checking specific travel dates for your route between Rome and San Donato Milanese as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Rome Leonardo da Vinci Fiumicino Airport and arrive in Milan Linate Airport.
- Trains mostly depart from Rome Termini and arrive in Milan Rogoredo.
- Buses mostly depart from Roma, Autostazione Tiburtina and arrive in Milano, San Donato - Settore B (Viale Giuseppe Impastato).
- Travel with FlixBus, Itabus, Marino Autolinee, Salemi to go to San Donato Milanese by bus.
- Travel with Italo, Intercity, Frecciarossa, Intercity Notte, Regionale to go to San Donato Milanese by train.
- Travel with ITA, British Airways, Lufthansa, Aeroitalia, Austrian Airlines, Swiss, Lufthansa City Airlines, Brussels Airlines to go to San Donato Milanese by flight.
- 8 direct buses per day with FlixBus, Itabus, Marino Autolinee, Salemi.
- 12 direct trains per day with Italo, Frecciarossa.
- 11 direct flights per day with ITA, Aeroitalia.
Travelling from Rome to San Donato Milanese: related information
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